Becki Lee
@beckilee.bsky.social
Melanoma oncologist at The Christie. Wellcome early career fellow at University of Manchester, The Francis Crick and UCL. Interested in tumour local and systemic immune changes, metastasis, ctdna and cancer evolution. Music, art, politics, hiking.
Cancer detectives a hit in our house!
Bench to bedside look at the DETECTION trial- Inspiring scientists of the future and an insight into why science is important, the breakthroughs they fund and what it means to the people involved
www.channel4.com/programmes/c...
Bench to bedside look at the DETECTION trial- Inspiring scientists of the future and an insight into why science is important, the breakthroughs they fund and what it means to the people involved
www.channel4.com/programmes/c...
November 22, 2025 at 10:54 AM
Cancer detectives a hit in our house!
Bench to bedside look at the DETECTION trial- Inspiring scientists of the future and an insight into why science is important, the breakthroughs they fund and what it means to the people involved
www.channel4.com/programmes/c...
Bench to bedside look at the DETECTION trial- Inspiring scientists of the future and an insight into why science is important, the breakthroughs they fund and what it means to the people involved
www.channel4.com/programmes/c...
Happy Halloween from these two!
October 31, 2025 at 6:27 AM
Happy Halloween from these two!
Melanoma UK today visited the Smiths Melanoma hub today learning about the amazing work all of these lovely people are doing! Thanks for funding us! @mcrcnews.bsky.social
October 16, 2025 at 10:57 AM
Melanoma UK today visited the Smiths Melanoma hub today learning about the amazing work all of these lovely people are doing! Thanks for funding us! @mcrcnews.bsky.social
Reposted by Becki Lee
Attending #ESMO25
Join us to learn about sustainability integration into cancer care and the environmental impacts of AI 👇
@myesmo.bsky.social @robchuter.bsky.social @beckilee.bsky.social @pawelsobczuk.bsky.social @ouchinternational.bsky.social @irishdocsenv.bsky.social @cancertrialsie.bsky.social
Join us to learn about sustainability integration into cancer care and the environmental impacts of AI 👇
@myesmo.bsky.social @robchuter.bsky.social @beckilee.bsky.social @pawelsobczuk.bsky.social @ouchinternational.bsky.social @irishdocsenv.bsky.social @cancertrialsie.bsky.social
October 14, 2025 at 5:31 PM
Attending #ESMO25
Join us to learn about sustainability integration into cancer care and the environmental impacts of AI 👇
@myesmo.bsky.social @robchuter.bsky.social @beckilee.bsky.social @pawelsobczuk.bsky.social @ouchinternational.bsky.social @irishdocsenv.bsky.social @cancertrialsie.bsky.social
Join us to learn about sustainability integration into cancer care and the environmental impacts of AI 👇
@myesmo.bsky.social @robchuter.bsky.social @beckilee.bsky.social @pawelsobczuk.bsky.social @ouchinternational.bsky.social @irishdocsenv.bsky.social @cancertrialsie.bsky.social
Amazing work throughout the UK to smash our recruitment target!
Congratulations to the DETECTION-2 team for reaching this recruitment milestone!
This #ClinicalTrial is seeing if a simple blood test can detect #melanoma returning earlier than a routine scan.
A larger phase III trial is now being planned.
Read more - bit.ly/3YRtqok
@cancerresearchuk.org
This #ClinicalTrial is seeing if a simple blood test can detect #melanoma returning earlier than a routine scan.
A larger phase III trial is now being planned.
Read more - bit.ly/3YRtqok
@cancerresearchuk.org
October 7, 2025 at 10:43 AM
Amazing work throughout the UK to smash our recruitment target!
Reposted by Becki Lee
We are pleased to announce the publication of our STEMM sector-wide survey
The report highlights our findings & suggests recommendations. Now available to download here carersinstemm.co.uk
Please share especially w/ institutions, funders & allies
@laurawolz.bsky.social @carterlj.bsky.social
The report highlights our findings & suggests recommendations. Now available to download here carersinstemm.co.uk
Please share especially w/ institutions, funders & allies
@laurawolz.bsky.social @carterlj.bsky.social
September 26, 2025 at 2:08 PM
We are pleased to announce the publication of our STEMM sector-wide survey
The report highlights our findings & suggests recommendations. Now available to download here carersinstemm.co.uk
Please share especially w/ institutions, funders & allies
@laurawolz.bsky.social @carterlj.bsky.social
The report highlights our findings & suggests recommendations. Now available to download here carersinstemm.co.uk
Please share especially w/ institutions, funders & allies
@laurawolz.bsky.social @carterlj.bsky.social
Reposted by Becki Lee
NEW: Nature trained AI to predict which NIH grants from 2014 would have been cut if the Trump admin had its way back then — and what science would have been lost to history.
"The results show the damage that cuts in funding can do to research, and the unpredictable nature of the research process."
"The results show the damage that cuts in funding can do to research, and the unpredictable nature of the research process."
We used machine-learning tools in an attempt to recreate the method for cutting funding, and then applied it to past US NIH grants to reveal the broad-reaching consequences
go.nature.com/4pBArFH
go.nature.com/4pBArFH
What research might be lost after the NIH’s cuts? Nature trained a bot to find out
We used machine-learning tools in an attempt to recreate the method for cutting funding, and then applied it to past US National Institutes of Health grants to reveal the broad-reaching consequences of such action.
go.nature.com
September 25, 2025 at 2:49 PM
NEW: Nature trained AI to predict which NIH grants from 2014 would have been cut if the Trump admin had its way back then — and what science would have been lost to history.
"The results show the damage that cuts in funding can do to research, and the unpredictable nature of the research process."
"The results show the damage that cuts in funding can do to research, and the unpredictable nature of the research process."
Reposted by Becki Lee
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
currentprotocols.onlinelibrary.wiley.com
September 19, 2025 at 2:39 PM
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
Very pleased to say DETECTION2 has just randomised it's 50th patient! Awesome work by patient groups @melanomafocus.bsky.social , UK clinical teams @christieinstitute.bsky.social R+I and SCTU funded by @cancerresearchuk.org
snoopy is standing in front of a fireworks display and says `` congratulations ! ''
Alt: snoopy is standing in front of a fireworks display and says `` congratulations ! ''
media.tenor.com
September 11, 2025 at 4:03 PM
Very pleased to say DETECTION2 has just randomised it's 50th patient! Awesome work by patient groups @melanomafocus.bsky.social , UK clinical teams @christieinstitute.bsky.social R+I and SCTU funded by @cancerresearchuk.org
Reposted by Becki Lee
v1.108 is rolling out today 🚚
Now live, at long last: Bookmarks, aka Saved Posts. For all those posts you'll definitely plan to come back to!
Update the app and give it a try. The button is right down there 👇
Now live, at long last: Bookmarks, aka Saved Posts. For all those posts you'll definitely plan to come back to!
Update the app and give it a try. The button is right down there 👇
September 8, 2025 at 6:24 PM
v1.108 is rolling out today 🚚
Now live, at long last: Bookmarks, aka Saved Posts. For all those posts you'll definitely plan to come back to!
Update the app and give it a try. The button is right down there 👇
Now live, at long last: Bookmarks, aka Saved Posts. For all those posts you'll definitely plan to come back to!
Update the app and give it a try. The button is right down there 👇
The Lee lab is expanding! We are really interested in mechanisms of local and systemic immune tolerance particularly in liver metastases - X2 research technicians
💡 Creative fun environment
🌱 Opportunities to grow
🫂 Highly collaborative with clinical+basic research
📢 Please spread word!
💡 Creative fun environment
🌱 Opportunities to grow
🫂 Highly collaborative with clinical+basic research
📢 Please spread word!
Research Technician:Oxford Road
www.jobs.manchester.ac.uk
August 22, 2025 at 4:03 PM
The Lee lab is expanding! We are really interested in mechanisms of local and systemic immune tolerance particularly in liver metastases - X2 research technicians
💡 Creative fun environment
🌱 Opportunities to grow
🫂 Highly collaborative with clinical+basic research
📢 Please spread word!
💡 Creative fun environment
🌱 Opportunities to grow
🫂 Highly collaborative with clinical+basic research
📢 Please spread word!
Reposted by Becki Lee
Calling all ECRs in cancer and metastasis research. Don't forget to register for the upcoming ECR Virtual Symposium in November (FREE for MRS members). More details here metastasis-research.org/2025/08/06/2...
August 6, 2025 at 7:05 AM
Calling all ECRs in cancer and metastasis research. Don't forget to register for the upcoming ECR Virtual Symposium in November (FREE for MRS members). More details here metastasis-research.org/2025/08/06/2...
⭐We have a clinical fellow opportunity with the melanoma team! ⭐
Very friendly and supportive team
Lots of learning opportunities including clinical trials and immune therapy
Apply here👇
urldefense.com/v3/__https:/...
Very friendly and supportive team
Lots of learning opportunities including clinical trials and immune therapy
Apply here👇
urldefense.com/v3/__https:/...
Job vacancy: Clinical Research Fellow, The Christie NHS Foundation Trust, Manchester | trac.jobs
urldefense.com
July 30, 2025 at 2:29 PM
⭐We have a clinical fellow opportunity with the melanoma team! ⭐
Very friendly and supportive team
Lots of learning opportunities including clinical trials and immune therapy
Apply here👇
urldefense.com/v3/__https:/...
Very friendly and supportive team
Lots of learning opportunities including clinical trials and immune therapy
Apply here👇
urldefense.com/v3/__https:/...
🚨 Exciting new paper alert 🚨 From the Marie lab
⭐They have identified new melanoblast cell states which are reawakened in metastasizing and immunotherapy resistant melanoma
⭐ Can target using hdac inhibitors
#melsm #melanoma #cancer
www.biorxiv.org/content/10.1...
⭐They have identified new melanoblast cell states which are reawakened in metastasizing and immunotherapy resistant melanoma
⭐ Can target using hdac inhibitors
#melsm #melanoma #cancer
www.biorxiv.org/content/10.1...
Transitory Schwann Cell Precursor and hybrid states underpin melanoma therapy resistance and metastasis
Melanoma plasticity, driven by phenotype state switching, underlies clinically relevant traits such as metastasis and therapy resistance. As melanoma progression is thought to recapitulate aspects of ...
www.biorxiv.org
July 24, 2025 at 4:21 AM
🚨 Exciting new paper alert 🚨 From the Marie lab
⭐They have identified new melanoblast cell states which are reawakened in metastasizing and immunotherapy resistant melanoma
⭐ Can target using hdac inhibitors
#melsm #melanoma #cancer
www.biorxiv.org/content/10.1...
⭐They have identified new melanoblast cell states which are reawakened in metastasizing and immunotherapy resistant melanoma
⭐ Can target using hdac inhibitors
#melsm #melanoma #cancer
www.biorxiv.org/content/10.1...
Reposted by Becki Lee
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
July 17, 2025 at 11:28 AM
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mathematical models and ctdna have reached the clinic - the ultimate personalised trial testing adaptive targeted therapy highlighted in the news today!
#EBEcancer25
www.express.co.uk/life-style/h...
#EBEcancer25
www.express.co.uk/life-style/h...
UK cancer breakthrough as simple blood test could help pinpoint treatment
EXCLUSIVE: Skin cancers can be among the most aggressive forms of the disease so using drugs to shrink them must be used with precision.
www.express.co.uk
July 2, 2025 at 5:29 PM
Mathematical models and ctdna have reached the clinic - the ultimate personalised trial testing adaptive targeted therapy highlighted in the news today!
#EBEcancer25
www.express.co.uk/life-style/h...
#EBEcancer25
www.express.co.uk/life-style/h...
Absolutely loving this course - fantastic discussions between all and the delegates and faculty. So many exciting Q's coming out of this!
Now medical oncologist and clinician scientist @beckilee.bsky.social leading the first clinical session. Discussing how to bring evolutionary and ecological ideas into molecular tumour boards, and how to design evo clinical trials for better treatment regimens. #EBEcancer25 @eventswcs.bsky.social
July 2, 2025 at 5:26 PM
Absolutely loving this course - fantastic discussions between all and the delegates and faculty. So many exciting Q's coming out of this!
Reposted by Becki Lee
Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer 👇🏽 Stellar work @colindhratcliffe.bsky.social www.biorxiv.org/content/10.1...
and also surprisingly/worryingly good AI generated podcast 🎧 notebooklm.google.com/notebook/28e...
and also surprisingly/worryingly good AI generated podcast 🎧 notebooklm.google.com/notebook/28e...
June 17, 2025 at 8:44 AM
Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer 👇🏽 Stellar work @colindhratcliffe.bsky.social www.biorxiv.org/content/10.1...
and also surprisingly/worryingly good AI generated podcast 🎧 notebooklm.google.com/notebook/28e...
and also surprisingly/worryingly good AI generated podcast 🎧 notebooklm.google.com/notebook/28e...
Reposted by Becki Lee
The deadline for early bird registration for the 5th Crick Cancer Conference has been extended.
See the full programme and book by 15 July to take advantage of reduced ticket rates for early bookers ⤵️ www.crick.ac.uk/whats-on/5th...
See the full programme and book by 15 July to take advantage of reduced ticket rates for early bookers ⤵️ www.crick.ac.uk/whats-on/5th...
5th Crick International Cancer Conference
www.crick.ac.uk
June 3, 2025 at 4:36 PM
The deadline for early bird registration for the 5th Crick Cancer Conference has been extended.
See the full programme and book by 15 July to take advantage of reduced ticket rates for early bookers ⤵️ www.crick.ac.uk/whats-on/5th...
See the full programme and book by 15 July to take advantage of reduced ticket rates for early bookers ⤵️ www.crick.ac.uk/whats-on/5th...
Super proud of our fellow Tomasso Bosetti presenting his poster at #ASCO25 on the impact of timing of immune therapy and outcomes across cancers - the early 🐦catches the 🪱!
June 3, 2025 at 6:05 PM
Super proud of our fellow Tomasso Bosetti presenting his poster at #ASCO25 on the impact of timing of immune therapy and outcomes across cancers - the early 🐦catches the 🪱!
Our data and the lung cancer trial also presented are very compelling for early time of day immune therapy treatment
urldefense.com/v3/__https:/...
urldefense.com/v3/__https:/...
June 3, 2025 at 6:20 AM
Our data and the lung cancer trial also presented are very compelling for early time of day immune therapy treatment
urldefense.com/v3/__https:/...
urldefense.com/v3/__https:/...
Reposted by Becki Lee
Single cell whizz with green fingers for molecular genomics? Want to develop and apply new technologies for profiling #cancer #evolution? Like single cell WGS + ATAC: www.biorxiv.org/content/10.1...
Perhaps our senior scientific officer role is for you?
jobs.icr.ac.uk/vacancies/12...
@icr.ac.uk
Perhaps our senior scientific officer role is for you?
jobs.icr.ac.uk/vacancies/12...
@icr.ac.uk
Higher or Senior Scientific Officer in Sutton | The Institute of Cancer Research
View details and apply for this Higher or Senior Scientific Officer vacancy in Sutton.
Salary : Salary from 39,805 to 49,023
Reporting to: Prof Trevor Graham
Duration of ...
jobs.icr.ac.uk
May 22, 2025 at 3:47 PM
Single cell whizz with green fingers for molecular genomics? Want to develop and apply new technologies for profiling #cancer #evolution? Like single cell WGS + ATAC: www.biorxiv.org/content/10.1...
Perhaps our senior scientific officer role is for you?
jobs.icr.ac.uk/vacancies/12...
@icr.ac.uk
Perhaps our senior scientific officer role is for you?
jobs.icr.ac.uk/vacancies/12...
@icr.ac.uk
Happy international trials day! Bit more info on one of the trials we have developed from research done @cruk-mi.bsky.social and now bringing to patients thanks to CRUK and @southamptonctu.bsky.social
On #InternationalClinicalTrialsDay, we share a Q&A about the DETECTION-2 clinical trial with Jemima Lawrance, a melanoma patient & patient representative on the trial and Dr
@beckilee.bsky.social one of the lead investigators, about the trial. buff.ly/ttajShm
@southamptonctu.bsky.social
@beckilee.bsky.social one of the lead investigators, about the trial. buff.ly/ttajShm
@southamptonctu.bsky.social
The DETECTION-2 Trial - Q&A with Dr Becki Lee and Jemima Lawrance
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
buff.ly
May 20, 2025 at 9:19 AM
Happy international trials day! Bit more info on one of the trials we have developed from research done @cruk-mi.bsky.social and now bringing to patients thanks to CRUK and @southamptonctu.bsky.social
Reposted by Becki Lee
The Department of Integrated Mathematical Oncology @mathonco.bsky.social (Moffitt Cancer Center, Tampa, Florida) is also advertising an Open Rank Tenure-earning Faculty Position in Mathematical Oncology. For this and other openings see mathematical-oncology.org/jobs
Jobs
mathematical-oncology.org
mathematical-oncology.org
May 6, 2025 at 10:49 AM
The Department of Integrated Mathematical Oncology @mathonco.bsky.social (Moffitt Cancer Center, Tampa, Florida) is also advertising an Open Rank Tenure-earning Faculty Position in Mathematical Oncology. For this and other openings see mathematical-oncology.org/jobs
Reposted by Becki Lee
Review @cp-immunity.bsky.social
Role of specialized sensory neuron subtypes in modulating peripheral immune responses
www.cell.com/immunity/ful...
Role of specialized sensory neuron subtypes in modulating peripheral immune responses
www.cell.com/immunity/ful...
May 5, 2025 at 8:06 PM
Review @cp-immunity.bsky.social
Role of specialized sensory neuron subtypes in modulating peripheral immune responses
www.cell.com/immunity/ful...
Role of specialized sensory neuron subtypes in modulating peripheral immune responses
www.cell.com/immunity/ful...