Rob Noble
@robjohnnoble.bsky.social
Senior Lecturer (≡ associate professor) in applied maths, investigating the evolution and ecology of cancer. Dad of two small kids. On sabbatical @isemevol.bsky.social 🇫🇷 (otherwise @citystgeorges.bsky.social 🇬🇧)
robjohnnoble.github.io
robjohnnoble.github.io
Yesterday I got a COVID booster at a French pharmacy for 7.50€. In the UK last year it cost me £100. It's worth a cross-Channel day trip just to get immunised.
November 9, 2025 at 10:38 AM
Yesterday I got a COVID booster at a French pharmacy for 7.50€. In the UK last year it cost me £100. It's worth a cross-Channel day trip just to get immunised.
Reposted by Rob Noble
James D. Watson died on Thursday in East Northport, N.Y., on Long Island. He was 97.
www.nytimes.com/2025/11/07/s...
www.nytimes.com/2025/11/07/s...
James Watson, Who Helped Discover the Structure of DNA, Is Dead at 97
www.nytimes.com
November 7, 2025 at 7:35 PM
James D. Watson died on Thursday in East Northport, N.Y., on Long Island. He was 97.
www.nytimes.com/2025/11/07/s...
www.nytimes.com/2025/11/07/s...
Reposted by Rob Noble
The deadline for applications is Nov 15 - please repost!
Join us at SFU for a 2-year Mekler Postdoctoral Fellowship in mathematical biology to work with me and Ailene MacPherson. Apply at www.mathjobs.org/jobs/list/27... by Nov 15.
MathJobs from the the American Mathematical Society
Mathjobs is an automated job application system sponsored by the AMS.
www.mathjobs.org
November 3, 2025 at 8:01 PM
The deadline for applications is Nov 15 - please repost!
Reposted by Rob Noble
Great last didactic at #MathOnco25 by @andriy-marusyk.bsky.social describing the complex landscape of evolutionary and ecological mechanisms aiding cancers become treatment-resistant. Andriy and I both share the idea of maps as an example of what models can be
October 31, 2025 at 4:05 PM
Great last didactic at #MathOnco25 by @andriy-marusyk.bsky.social describing the complex landscape of evolutionary and ecological mechanisms aiding cancers become treatment-resistant. Andriy and I both share the idea of maps as an example of what models can be
In her #MathOnco25 plenary, Sarah Brüningk motivates mechanistic learning in mathematical oncology, drawing on her recent review paper: www.frontiersin.org/journals/imm...
October 31, 2025 at 1:16 PM
In her #MathOnco25 plenary, Sarah Brüningk motivates mechanistic learning in mathematical oncology, drawing on her recent review paper: www.frontiersin.org/journals/imm...
Bob Gatenby finishes his phenomenal #MathOnco25 talk with this stunning figure and conclusion: "Cycles within cycles may allow metastatic prostate cancer to be converted to a chronic disease". The results are from a new paper: onlinelibrary.wiley.com/doi/10.1002/...
October 30, 2025 at 9:23 PM
Bob Gatenby finishes his phenomenal #MathOnco25 talk with this stunning figure and conclusion: "Cycles within cycles may allow metastatic prostate cancer to be converted to a chronic disease". The results are from a new paper: onlinelibrary.wiley.com/doi/10.1002/...
Joel Brown at #MathOnco25 draws parallels between the evolution and ecology of cancer and of dogs, elephant shrews and (of course) squirrels. Cancer redefined as "a disease of uncontrolled proliferation by transformed cells subject to evolution by natural selection". aacrjournals.org/mcr/article/...
October 30, 2025 at 6:19 PM
Joel Brown at #MathOnco25 draws parallels between the evolution and ecology of cancer and of dogs, elephant shrews and (of course) squirrels. Cancer redefined as "a disease of uncontrolled proliferation by transformed cells subject to evolution by natural selection". aacrjournals.org/mcr/article/...
Now @kitcgallagher.bsky.social at #MathOnco25 presents his recent research on predicting treatment outcomes to identify which patients will benefit the most from adaptive therapy. Preprints and papers at scholar.google.com/citations?us...
October 30, 2025 at 4:04 PM
Now @kitcgallagher.bsky.social at #MathOnco25 presents his recent research on predicting treatment outcomes to identify which patients will benefit the most from adaptive therapy. Preprints and papers at scholar.google.com/citations?us...
Franco Pradelli presents one of the most beautiful slides so far at #MathOnco25, on the topic of exploiting the cost of addiction in anaplastic large cell lymphoma
October 30, 2025 at 3:47 PM
Franco Pradelli presents one of the most beautiful slides so far at #MathOnco25, on the topic of exploiting the cost of addiction in anaplastic large cell lymphoma
Fantastic to have adaptive therapy pioneer Jingsong Zhang here at #MathOnco25 talking about a third-generation adaptive therapy trial for metastatic prostate cancer underway at the Moffitt Cancer Center, informed by Jill Gallagher's mathematical modelling. Preprint: www.medrxiv.org/content/10.1...
October 30, 2025 at 3:36 PM
Fantastic to have adaptive therapy pioneer Jingsong Zhang here at #MathOnco25 talking about a third-generation adaptive therapy trial for metastatic prostate cancer underway at the Moffitt Cancer Center, informed by Jill Gallagher's mathematical modelling. Preprint: www.medrxiv.org/content/10.1...
Reposted by Rob Noble
Thursday keynote at #MathOnco25 with @robjohnnoble.bsky.social showing a wealth of #MathOnco models of cancer evolution and evolutionary-enlightened therapies. Notice the bingo card: he showed enough different math models to fill up the card!
October 30, 2025 at 2:00 PM
Thursday keynote at #MathOnco25 with @robjohnnoble.bsky.social showing a wealth of #MathOnco models of cancer evolution and evolutionary-enlightened therapies. Notice the bingo card: he showed enough different math models to fill up the card!
Really nice #MathOnco25 talk by Einar Bjarki Gunnarsson on optimal dosing of anti-cancer treatment under drug-induced plasticity, showing "that the optimal dosing strategy steers the tumor to a fixed equilibrium composition between sensitive and tolerant cells" www.nature.com/articles/s41...
Optimal dosing of anti-cancer treatment under drug-induced plasticity - npj Systems Biology and Applications
npj Systems Biology and Applications - Optimal dosing of anti-cancer treatment under drug-induced plasticity
www.nature.com
October 29, 2025 at 9:36 PM
Really nice #MathOnco25 talk by Einar Bjarki Gunnarsson on optimal dosing of anti-cancer treatment under drug-induced plasticity, showing "that the optimal dosing strategy steers the tumor to a fixed equilibrium composition between sensitive and tolerant cells" www.nature.com/articles/s41...
Now at #MathOnco25, co-organiser @gliomath.bsky.social presents recent work showing that the predictions of an AI method massively improved when coupled with a mechnaistic mathematical model www.nature.com/articles/s41...
Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma - npj Digital Medicine
npj Digital Medicine - Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma
www.nature.com
October 29, 2025 at 9:22 PM
Now at #MathOnco25, co-organiser @gliomath.bsky.social presents recent work showing that the predictions of an AI method massively improved when coupled with a mechnaistic mathematical model www.nature.com/articles/s41...
Reposted by Rob Noble
Great talk by collaborator Joon Hyun Song from @ceel-damaghilab.bsky.social working on a simple model of the storage effect to explain the role of temporal fluctuations in intra tumor heterogeneity #MathOnco25
October 29, 2025 at 8:22 PM
Great talk by collaborator Joon Hyun Song from @ceel-damaghilab.bsky.social working on a simple model of the storage effect to explain the role of temporal fluctuations in intra tumor heterogeneity #MathOnco25
Reposted by Rob Noble
Great didactic at #MathOnco25 by @rrockne.bsky.social who starts his presentation with a very Freudian slip by thanking organizers @gliomath.bsky.social and #SINDy (meaning @sandyanderson.bsky.social)
October 29, 2025 at 3:49 PM
Great didactic at #MathOnco25 by @rrockne.bsky.social who starts his presentation with a very Freudian slip by thanking organizers @gliomath.bsky.social and #SINDy (meaning @sandyanderson.bsky.social)
Reposted by Rob Noble
How bowhead whales live for centuries—and how we might borrow some of their biology to extend our healthy lifespan. Gift link to my new column: nyti.ms/4hyD9ry
October 29, 2025 at 4:33 PM
How bowhead whales live for centuries—and how we might borrow some of their biology to extend our healthy lifespan. Gift link to my new column: nyti.ms/4hyD9ry
At #MathOnco25, @rrockne.bsky.social explains why he so loves SINDy (sparse identification of nonlinear dynamics).
October 29, 2025 at 4:19 PM
At #MathOnco25, @rrockne.bsky.social explains why he so loves SINDy (sparse identification of nonlinear dynamics).
Phenomenal talk. I've never seen a more elegant integration of mathematical modelling and molecular biology. #MathOnco25
First plenary talk at #MathOnco25 today is Harvard's Galit Lahav about the temporal dynamics of p53 and how it lends itself to #MathModeling
Galit Lahav - Wikipedia
en.wikipedia.org
October 29, 2025 at 1:54 PM
Phenomenal talk. I've never seen a more elegant integration of mathematical modelling and molecular biology. #MathOnco25
Reposted by Rob Noble
Our own Tatiana Miti highlighting the importance of data to find out the initial configuration of an ABM describing early stages in metastasis, something which is hard to study with experimental models and clinical data #MathOnco25
October 28, 2025 at 9:57 PM
Our own Tatiana Miti highlighting the importance of data to find out the initial configuration of an ABM describing early stages in metastasis, something which is hard to study with experimental models and clinical data #MathOnco25
Reposted by Rob Noble
Great didactic at #MathOnco25 by @dwodarz.bsky.social showing the importance of space...and turnover in #cancerevolution
October 28, 2025 at 9:59 PM
Great didactic at #MathOnco25 by @dwodarz.bsky.social showing the importance of space...and turnover in #cancerevolution
A man after my own heart! @dwodarz.bsky.social on the importance of spatial structure in tumour evolution #MathOnco25
October 28, 2025 at 9:02 PM
A man after my own heart! @dwodarz.bsky.social on the importance of spatial structure in tumour evolution #MathOnco25
At #MathOnco25, @cancerevo.org talks about how to model the role of the tumor microenvironment in cancer initiation, progression, and treatment resistance. He finishes by advertising the Moffitt IMO PhD program www.moffitt.org/education/re...
October 28, 2025 at 8:12 PM
At #MathOnco25, @cancerevo.org talks about how to model the role of the tumor microenvironment in cancer initiation, progression, and treatment resistance. He finishes by advertising the Moffitt IMO PhD program www.moffitt.org/education/re...
Now at #MathOnco25, @ceel-damaghilab.bsky.social advocates "3D spheroids as a simplest model of tumor ecosystem". His beautiful data make a strong case.
October 28, 2025 at 7:36 PM
Now at #MathOnco25, @ceel-damaghilab.bsky.social advocates "3D spheroids as a simplest model of tumor ecosystem". His beautiful data make a strong case.
Reposted by Rob Noble
First didactic of the day at #MathOnco25 is Stony Brook's @ceel-damaghilab.bsky.social about the breast ecosystem. The early breast cancer ecosystem is a tumor incubator
October 28, 2025 at 7:18 PM
First didactic of the day at #MathOnco25 is Stony Brook's @ceel-damaghilab.bsky.social about the breast ecosystem. The early breast cancer ecosystem is a tumor incubator
Setting the tone for #MathOnco25, @stroblmar.bsky.social (now based in London) outlines the benefits of theory-experiment integration
October 28, 2025 at 6:12 PM
Setting the tone for #MathOnco25, @stroblmar.bsky.social (now based in London) outlines the benefits of theory-experiment integration