A.S.Brumm
@asbrumm.bsky.social
PostDoc with Sally Lowell @cellysally.bsky.social at the University of Edinburgh, previously PhD Student with Kathy Niakan at the Francis Crick Institute @thecrick.bsky.social.
Reposted by A.S.Brumm
new out in Nature www.nature.com/articles/d41...
John Gurdon obituary: Biologist who made cloning possible
He showed that specialized cells retain the genes to form an organism.
www.nature.com
October 21, 2025 at 7:22 AM
new out in Nature www.nature.com/articles/d41...
Reposted by A.S.Brumm
One of our favourite tabs is Resources: we're listing all of our datasets, codes, beginning to upload and make accessible raw imaging data and lab protocols. Please check it out, we hope this is useful!
niakanlab.com/resources/
niakanlab.com/resources/
September 30, 2025 at 5:57 PM
One of our favourite tabs is Resources: we're listing all of our datasets, codes, beginning to upload and make accessible raw imaging data and lab protocols. Please check it out, we hope this is useful!
niakanlab.com/resources/
niakanlab.com/resources/
Reposted by A.S.Brumm
Found this unbelievably accurate “integrated stem
cell model” by JA Thomson in 1996 of marmoset ESCs 🐒
pubmed.ncbi.nlm.nih.gov/8828827/
The simplest protocol one can think of built quite remarkable structures !?!?
cell model” by JA Thomson in 1996 of marmoset ESCs 🐒
pubmed.ncbi.nlm.nih.gov/8828827/
The simplest protocol one can think of built quite remarkable structures !?!?
July 24, 2025 at 7:31 PM
Found this unbelievably accurate “integrated stem
cell model” by JA Thomson in 1996 of marmoset ESCs 🐒
pubmed.ncbi.nlm.nih.gov/8828827/
The simplest protocol one can think of built quite remarkable structures !?!?
cell model” by JA Thomson in 1996 of marmoset ESCs 🐒
pubmed.ncbi.nlm.nih.gov/8828827/
The simplest protocol one can think of built quite remarkable structures !?!?
Reposted by A.S.Brumm
Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu
July 16, 2025 at 1:07 PM
Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu
Reposted by A.S.Brumm
Can peer review be done faster, without compromising on quality? Biology Open has embarked on an exciting experiment to find out - Editor-in-Chief Dan Gorelick @danielgorelick.bsky.social explains.
www.youtube.com/watch?v=Tt5h...
www.youtube.com/watch?v=Tt5h...
Why is Biology Open's Fast & Fair peer review initiative exciting?
YouTube video by The Company of Biologists
www.youtube.com
July 1, 2025 at 8:54 AM
Can peer review be done faster, without compromising on quality? Biology Open has embarked on an exciting experiment to find out - Editor-in-Chief Dan Gorelick @danielgorelick.bsky.social explains.
www.youtube.com/watch?v=Tt5h...
www.youtube.com/watch?v=Tt5h...
Reposted by A.S.Brumm
Join us! This will be a great meeting.
Are you a biologist with a research interest in #embryogenesis or synthetic biology? Join our upcoming residential scientific meeting in Brighton on the topic of generative biology: royalsociety.org/science-even... @jcornwallscoones.bsky.social @dbenzinger.bsky.social @cellysally.bsky.social
June 24, 2025 at 11:35 AM
Join us! This will be a great meeting.
Our protocol with all the details you'll need to detect and quantify phospo-SMAD proteins in your (human) embryo, is finally out today @cp-starprotocols.bsky.social.
Thanks again to my wonderful co-author @toddfallesen.bsky.social and the @niakanlab.bsky.social.
www.sciencedirect.com/science/arti...
Thanks again to my wonderful co-author @toddfallesen.bsky.social and the @niakanlab.bsky.social.
www.sciencedirect.com/science/arti...
Protocol for immunofluorescence detection and quantification of phosphorylated SMAD proteins in human blastocysts
The transforming growth factor β (TGF-β) signaling superfamily includes NODAL and bone morphogenetic protein (BMP) signaling, which lead to the phosph…
www.sciencedirect.com
May 28, 2025 at 9:42 AM
Our protocol with all the details you'll need to detect and quantify phospo-SMAD proteins in your (human) embryo, is finally out today @cp-starprotocols.bsky.social.
Thanks again to my wonderful co-author @toddfallesen.bsky.social and the @niakanlab.bsky.social.
www.sciencedirect.com/science/arti...
Thanks again to my wonderful co-author @toddfallesen.bsky.social and the @niakanlab.bsky.social.
www.sciencedirect.com/science/arti...
Reposted by A.S.Brumm
If you’re a PhD or postdoc developmental biologist in the UK who cares about the field and the community, please nominate yourself to join the BSDB committee. Great opportunity to get involved, have real input and give back to the community @bsdb.bsky.social #biologists100
March 25, 2025 at 5:19 PM
If you’re a PhD or postdoc developmental biologist in the UK who cares about the field and the community, please nominate yourself to join the BSDB committee. Great opportunity to get involved, have real input and give back to the community @bsdb.bsky.social #biologists100
Excited to share how we use neighbour labelling to investigate cell fate decisions in neuromesodermal progenitors. Find me at Poster 165 @biologists.bsky.social #biologists100.
March 24, 2025 at 3:46 PM
Excited to share how we use neighbour labelling to investigate cell fate decisions in neuromesodermal progenitors. Find me at Poster 165 @biologists.bsky.social #biologists100.
Reposted by A.S.Brumm
🧪Attending your first scientific #conference? Thinking about what to pack, or just looking to make sure you prepared all the essentials? Have a look at The Beginner’s Guide to Scientific Conferences I got to publish for @the-node.bsky.social, out now! ☺️☺️ thenode.biologists.com/the-beginner...
the-beginners-guide-to-scientific-conferences
The Beginners Guide to Scientific Conferences
thenode.biologists.com
March 17, 2025 at 4:02 PM
🧪Attending your first scientific #conference? Thinking about what to pack, or just looking to make sure you prepared all the essentials? Have a look at The Beginner’s Guide to Scientific Conferences I got to publish for @the-node.bsky.social, out now! ☺️☺️ thenode.biologists.com/the-beginner...
Reposted by A.S.Brumm
Have you been following the work of the HDBI - the Human Developmental Biology Initiative? A lay summary of a recent paper from researchers involved in the HDBI is now available, written by the paper's first author @asbrumm.bsky.social
hdbi.org/human-epibla...
#Embryos #HumanDevelopment
hdbi.org/human-epibla...
#Embryos #HumanDevelopment
February 26, 2025 at 10:19 AM
Have you been following the work of the HDBI - the Human Developmental Biology Initiative? A lay summary of a recent paper from researchers involved in the HDBI is now available, written by the paper's first author @asbrumm.bsky.social
hdbi.org/human-epibla...
#Embryos #HumanDevelopment
hdbi.org/human-epibla...
#Embryos #HumanDevelopment
Reposted by A.S.Brumm
www.biorxiv.org/content/10.1...
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan
Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that ...
www.biorxiv.org
January 13, 2025 at 11:36 AM
www.biorxiv.org/content/10.1...
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.