Babraham Institute
@babrahaminst.bsky.social
We make discoveries that help us understand human biology and improve lifelong health. Leaders in #AgeingResearch and cell biology.
Research themes in #Epigenetics, #Immunology and #Signalling
📌 Cambridge, UK
Funded by UKRI-BBSRC
Research themes in #Epigenetics, #Immunology and #Signalling
📌 Cambridge, UK
Funded by UKRI-BBSRC
Happy holidays from all of us at the Babraham Institute!✨Our card includes an image of a mouse intestine that has been stained for DNA (blue), e-cadherin (green) and muc2 (red). 📸 Petrina Tan, Christophorou lab
December 24, 2025 at 12:42 PM
Happy holidays from all of us at the Babraham Institute!✨Our card includes an image of a mouse intestine that has been stained for DNA (blue), e-cadherin (green) and muc2 (red). 📸 Petrina Tan, Christophorou lab
Reposted by Babraham Institute
Our team has successfully achieved human embryo implantation in the lab using a 3D endometrial scaffold.
The Goal: Implantation is of the biggest hurdle in pregnancy. By understanding this process in the lab, we can develop new therapeutics to improve clinical outcomes and IVF success rates.
The Goal: Implantation is of the biggest hurdle in pregnancy. By understanding this process in the lab, we can develop new therapeutics to improve clinical outcomes and IVF success rates.
December 24, 2025 at 11:21 AM
Our team has successfully achieved human embryo implantation in the lab using a 3D endometrial scaffold.
The Goal: Implantation is of the biggest hurdle in pregnancy. By understanding this process in the lab, we can develop new therapeutics to improve clinical outcomes and IVF success rates.
The Goal: Implantation is of the biggest hurdle in pregnancy. By understanding this process in the lab, we can develop new therapeutics to improve clinical outcomes and IVF success rates.
Reposted by Babraham Institute
Christmas has come early. Fantastic to see this beautiful study from Peter Rugg-Gunn's lab at The Babraham Institute published today. Congratulations to Matteo Mole, Sarah Elderkin, Irene Zorzan and all other authors!
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Modeling human embryo implantation in vitro
Building an in vitro model of receptive endometrium allows investigation of human
embryo implantation and early post-implantation development and recapitulates the
earliest stages in establishing the ...
www.cell.com
December 23, 2025 at 3:55 PM
Christmas has come early. Fantastic to see this beautiful study from Peter Rugg-Gunn's lab at The Babraham Institute published today. Congratulations to Matteo Mole, Sarah Elderkin, Irene Zorzan and all other authors!
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
NEWS | Researchers ‘listen in’ to embryo-mother interactions during implantation using a culture system replicating the womb lining
www.babraham.ac.uk/news/2025/12...
www.babraham.ac.uk/news/2025/12...
December 23, 2025 at 4:26 PM
NEWS | Researchers ‘listen in’ to embryo-mother interactions during implantation using a culture system replicating the womb lining
www.babraham.ac.uk/news/2025/12...
www.babraham.ac.uk/news/2025/12...
Christmas special: buy one ticket, bring a colleague for free!
Join leading academics, industry experts, and biotech innovators and explore next-generation stem cell technology, disease modelling, and translational breakthroughs at the Frontiers in Stem Cell Innovation Conference!
buff.ly/oMmTmYd
Join leading academics, industry experts, and biotech innovators and explore next-generation stem cell technology, disease modelling, and translational breakthroughs at the Frontiers in Stem Cell Innovation Conference!
buff.ly/oMmTmYd
December 15, 2025 at 1:45 PM
Christmas special: buy one ticket, bring a colleague for free!
Join leading academics, industry experts, and biotech innovators and explore next-generation stem cell technology, disease modelling, and translational breakthroughs at the Frontiers in Stem Cell Innovation Conference!
buff.ly/oMmTmYd
Join leading academics, industry experts, and biotech innovators and explore next-generation stem cell technology, disease modelling, and translational breakthroughs at the Frontiers in Stem Cell Innovation Conference!
buff.ly/oMmTmYd
Earlybird deadline extended 🚨Join us at the Frontiers in Stem Cell Innovation (FISCI) Conference on the 5th –6th February 2026 in Cambridge.
Up to 50% off ends 16th January: www.eventbrite.co.uk/e/frontiers-...
Up to 50% off ends 16th January: www.eventbrite.co.uk/e/frontiers-...
Frontiers in Stem Cell Innovation 2026
Join leading academics and industry professionals exploring cutting-edge stem cell technologies and disease modelling for drug discovery
www.eventbrite.co.uk
December 5, 2025 at 4:52 PM
Earlybird deadline extended 🚨Join us at the Frontiers in Stem Cell Innovation (FISCI) Conference on the 5th –6th February 2026 in Cambridge.
Up to 50% off ends 16th January: www.eventbrite.co.uk/e/frontiers-...
Up to 50% off ends 16th January: www.eventbrite.co.uk/e/frontiers-...
Reposted by Babraham Institute
www.embopress.org/doi/full/10....
Congratulations to Suzan Ber and @aesposito1975.bsky.social on their lovely study of KRAS alleles on glutamine and nitrogen metablism and signalling - just out in EMBO Reports. Such a pleasure to collaborate on this fascinating project! 👏
Congratulations to Suzan Ber and @aesposito1975.bsky.social on their lovely study of KRAS alleles on glutamine and nitrogen metablism and signalling - just out in EMBO Reports. Such a pleasure to collaborate on this fascinating project! 👏
FOXO1 links KRAS G12D and G12V alleles to glutamine and nitrogen metabolism in colorectal cancer | EMBO reports
imageimageKRAS mutations at codon 12 induce profound metabolic changes in colorectal cancer
cells. These oncogenic mutations promote FOXO1-dependent glutamine and nitrogen recycling,
uncovering a vuln...
www.embopress.org
November 21, 2025 at 9:20 AM
www.embopress.org/doi/full/10....
Congratulations to Suzan Ber and @aesposito1975.bsky.social on their lovely study of KRAS alleles on glutamine and nitrogen metablism and signalling - just out in EMBO Reports. Such a pleasure to collaborate on this fascinating project! 👏
Congratulations to Suzan Ber and @aesposito1975.bsky.social on their lovely study of KRAS alleles on glutamine and nitrogen metablism and signalling - just out in EMBO Reports. Such a pleasure to collaborate on this fascinating project! 👏
Reposted by Babraham Institute
I’m really pleased to share the link to a new Cook Lab paper published today in Nature Communications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
RAF inhibitors activate the integrated stress response by direct activation of GCN2 - Nature Communications
Three BRAF inhibitors are used to treat melanoma and colorectal cancer. Here, the authors demonstrate that these drugs bind and activate the protein kinase GCN2, a previously unappreciated off-target ...
www.nature.com
November 17, 2025 at 12:12 PM
I’m really pleased to share the link to a new Cook Lab paper published today in Nature Communications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Babraham Institute
🚨UK Ageing Research League Table update
@babrahaminst.bsky.social claims 1st 🥇
@unibirmingham.bsky.social in 2nd 🥈
@ox.ac.uk in 3rd 🥉
@ucl.ac.uk & (bluesky shy?) Univeristy of Westmisnter narroly miss the podium & are tied for 4th.
How did your institution rank?
bsra.org.uk/uk-ageing-re...
@babrahaminst.bsky.social claims 1st 🥇
@unibirmingham.bsky.social in 2nd 🥈
@ox.ac.uk in 3rd 🥉
@ucl.ac.uk & (bluesky shy?) Univeristy of Westmisnter narroly miss the podium & are tied for 4th.
How did your institution rank?
bsra.org.uk/uk-ageing-re...
UK Ageing Research League Table update Sept 2025 - BSRA
bsra.org.uk
November 17, 2025 at 10:40 AM
🚨UK Ageing Research League Table update
@babrahaminst.bsky.social claims 1st 🥇
@unibirmingham.bsky.social in 2nd 🥈
@ox.ac.uk in 3rd 🥉
@ucl.ac.uk & (bluesky shy?) Univeristy of Westmisnter narroly miss the podium & are tied for 4th.
How did your institution rank?
bsra.org.uk/uk-ageing-re...
@babrahaminst.bsky.social claims 1st 🥇
@unibirmingham.bsky.social in 2nd 🥈
@ox.ac.uk in 3rd 🥉
@ucl.ac.uk & (bluesky shy?) Univeristy of Westmisnter narroly miss the podium & are tied for 4th.
How did your institution rank?
bsra.org.uk/uk-ageing-re...
The countdown is on! One week left for early birds to get their tickets to the Frontiers in Stem Cell Innovation conference 🎟️
📅 5–6 February 2026
📍 Cambridge, UK
Hosted by The Babraham Institute and Newcastle University.
Register now www.eventbrite.co.uk/e/frontiers-...
📅 5–6 February 2026
📍 Cambridge, UK
Hosted by The Babraham Institute and Newcastle University.
Register now www.eventbrite.co.uk/e/frontiers-...
Frontiers in Stem Cell Innovation 2026
Join leading academics and industry professionals exploring cutting-edge stem cell technologies and disease modelling for drug discovery
www.eventbrite.co.uk
November 14, 2025 at 4:44 PM
The countdown is on! One week left for early birds to get their tickets to the Frontiers in Stem Cell Innovation conference 🎟️
📅 5–6 February 2026
📍 Cambridge, UK
Hosted by The Babraham Institute and Newcastle University.
Register now www.eventbrite.co.uk/e/frontiers-...
📅 5–6 February 2026
📍 Cambridge, UK
Hosted by The Babraham Institute and Newcastle University.
Register now www.eventbrite.co.uk/e/frontiers-...
It’s #AnimalStats day in the UK today. You can see our animal stats at any time on our website, as well as finding out how and why we use mice in our research.
www.babraham.ac.uk/our-research...
www.babraham.ac.uk/our-research...
October 23, 2025 at 9:57 AM
It’s #AnimalStats day in the UK today. You can see our animal stats at any time on our website, as well as finding out how and why we use mice in our research.
www.babraham.ac.uk/our-research...
www.babraham.ac.uk/our-research...
Reposted by Babraham Institute
Check out the line up of amazing speakers at the 2026 GRC Autophagy meeting in Ventura, California, 15-20 March. Register now and share your latest findings.
www.grc.org/autophagy-in...
www.grc.org/autophagy-in...
2026 Autophagy in Stress, Development and Disease Conference GRC
The 2026 Gordon Research Conference on Autophagy in Stress, Development and Disease will be held in Ventura, California. Apply today to reserve your spot.
www.grc.org
October 21, 2025 at 10:28 AM
Check out the line up of amazing speakers at the 2026 GRC Autophagy meeting in Ventura, California, 15-20 March. Register now and share your latest findings.
www.grc.org/autophagy-in...
www.grc.org/autophagy-in...
Interested in #StemCell research and technologies? Then hopefully this pairing of events is already marked in your calendar for February 2026. If not, take a longer look!
www.eventbrite.co.uk/e/frontiers-...
www.eventbrite.co.uk/e/frontiers-...
October 16, 2025 at 3:38 PM
Interested in #StemCell research and technologies? Then hopefully this pairing of events is already marked in your calendar for February 2026. If not, take a longer look!
www.eventbrite.co.uk/e/frontiers-...
www.eventbrite.co.uk/e/frontiers-...
Reposted by Babraham Institute
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
Postdoctoral Researcher (Howard Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.
www.jic.ac.uk
October 6, 2025 at 4:49 PM
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
ICYM our announcement from last week: Two incredible events unite to make one unmissable opportunity!
www.eventbrite.co.uk/e/frontiers-...
www.eventbrite.co.uk/e/frontiers-...
October 6, 2025 at 11:32 AM
ICYM our announcement from last week: Two incredible events unite to make one unmissable opportunity!
www.eventbrite.co.uk/e/frontiers-...
www.eventbrite.co.uk/e/frontiers-...
NEW PUBLICATION | A research collaboration between the Rugg-Gunn lab and Lonza is moving researchers towards the ability to drive transgene expression (in CHO cells) at higher levels to improve biopharmaceuticals yields.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10....
analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10....
Comprehensive Mapping of Functional Enhancers in Chinese Hamster Ovary Cells
analyticalsciencejournals.onlinelibrary.wiley.com
October 6, 2025 at 8:44 AM
NEW PUBLICATION | A research collaboration between the Rugg-Gunn lab and Lonza is moving researchers towards the ability to drive transgene expression (in CHO cells) at higher levels to improve biopharmaceuticals yields.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10....
analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10....
Reposted by Babraham Institute
🚀 Applications are open for the Bio-spark Entrepreneurial Programme!
Are you an early career researcher hoping to consider options outside the academic world? Are you looking for advice, experience or mentorship?
🗓️ Apply by 13 Oct
🔗 www.gravity.cam.ac.u...
Are you an early career researcher hoping to consider options outside the academic world? Are you looking for advice, experience or mentorship?
🗓️ Apply by 13 Oct
🔗 www.gravity.cam.ac.u...
September 29, 2025 at 7:00 AM
🚀 Applications are open for the Bio-spark Entrepreneurial Programme!
Are you an early career researcher hoping to consider options outside the academic world? Are you looking for advice, experience or mentorship?
🗓️ Apply by 13 Oct
🔗 www.gravity.cam.ac.u...
Are you an early career researcher hoping to consider options outside the academic world? Are you looking for advice, experience or mentorship?
🗓️ Apply by 13 Oct
🔗 www.gravity.cam.ac.u...
3 days - 2 events - 1 amazing opportunity!
Get set for two events showcasing bioscience innovation.
4-5 Feb - WORD+ 2026 event
5-6 Feb - our Frontiers in Stem Cell Innovation (FISCI) conference
📍Cambridge
Registration for FISCI is open now: www.eventbrite.co.uk/e/frontiers-...
Get set for two events showcasing bioscience innovation.
4-5 Feb - WORD+ 2026 event
5-6 Feb - our Frontiers in Stem Cell Innovation (FISCI) conference
📍Cambridge
Registration for FISCI is open now: www.eventbrite.co.uk/e/frontiers-...
Frontiers in Stem Cell Innovation 2026
Join leading academics and industry professionals exploring cutting-edge stem cell technologies and disease modelling for drug discovery
www.eventbrite.co.uk
September 30, 2025 at 2:27 PM
3 days - 2 events - 1 amazing opportunity!
Get set for two events showcasing bioscience innovation.
4-5 Feb - WORD+ 2026 event
5-6 Feb - our Frontiers in Stem Cell Innovation (FISCI) conference
📍Cambridge
Registration for FISCI is open now: www.eventbrite.co.uk/e/frontiers-...
Get set for two events showcasing bioscience innovation.
4-5 Feb - WORD+ 2026 event
5-6 Feb - our Frontiers in Stem Cell Innovation (FISCI) conference
📍Cambridge
Registration for FISCI is open now: www.eventbrite.co.uk/e/frontiers-...
NEWS | A new multi-omics method enabling the profiling of multiple histone modifications and gene expression in single cells, and the researchers behind it, have been recognised with two awards. Congrats to the Rugg-Gunn lab and everyone involved!
www.babraham.ac.uk/news/2025/09...
#epigenetics
www.babraham.ac.uk/news/2025/09...
#epigenetics
September 30, 2025 at 10:33 AM
NEWS | A new multi-omics method enabling the profiling of multiple histone modifications and gene expression in single cells, and the researchers behind it, have been recognised with two awards. Congrats to the Rugg-Gunn lab and everyone involved!
www.babraham.ac.uk/news/2025/09...
#epigenetics
www.babraham.ac.uk/news/2025/09...
#epigenetics
Reposted by Babraham Institute
Publishing Your Research? Resource for early career researchers from Alzheimer's Society Retreat
Dr Johanna Jackson @imperialcollegeldn.bsky.social
Dr Simon Andrews @babrahaminst.bsky.social
Dr Christian Schnell @plosbiology.org
Cherie Nyota @alzheimerssoc.bsky.social
youtu.be/ACqKndCoM3Q?...
Dr Johanna Jackson @imperialcollegeldn.bsky.social
Dr Simon Andrews @babrahaminst.bsky.social
Dr Christian Schnell @plosbiology.org
Cherie Nyota @alzheimerssoc.bsky.social
youtu.be/ACqKndCoM3Q?...
Advise on Publishing Your Research
YouTube video by Dementia Researcher
youtu.be
September 29, 2025 at 2:19 PM
Publishing Your Research? Resource for early career researchers from Alzheimer's Society Retreat
Dr Johanna Jackson @imperialcollegeldn.bsky.social
Dr Simon Andrews @babrahaminst.bsky.social
Dr Christian Schnell @plosbiology.org
Cherie Nyota @alzheimerssoc.bsky.social
youtu.be/ACqKndCoM3Q?...
Dr Johanna Jackson @imperialcollegeldn.bsky.social
Dr Simon Andrews @babrahaminst.bsky.social
Dr Christian Schnell @plosbiology.org
Cherie Nyota @alzheimerssoc.bsky.social
youtu.be/ACqKndCoM3Q?...
Reposted by Babraham Institute
We've updated our first #preprint from the lab! A collaboration with @jamesbriscoe.bsky.social
🔥 now including in vivo 🐭&👤 embryo data
www.biorxiv.org/content/10.1...
🔥 now including in vivo 🐭&👤 embryo data
www.biorxiv.org/content/10.1...
September 28, 2025 at 10:05 AM
We've updated our first #preprint from the lab! A collaboration with @jamesbriscoe.bsky.social
🔥 now including in vivo 🐭&👤 embryo data
www.biorxiv.org/content/10.1...
🔥 now including in vivo 🐭&👤 embryo data
www.biorxiv.org/content/10.1...
Reposted by Babraham Institute
2nd Meeting on Early Embryogenesis and Epigenetics
16 - 18 Feb 2026 at MPI for Molecular Genetics, Berlin
with support by the Weizmann Institute for Science.
Early bird registration until 30 Sep - register now👇
www.molgen.mpg.de/embryo2026
16 - 18 Feb 2026 at MPI for Molecular Genetics, Berlin
with support by the Weizmann Institute for Science.
Early bird registration until 30 Sep - register now👇
www.molgen.mpg.de/embryo2026
September 26, 2025 at 1:09 PM
2nd Meeting on Early Embryogenesis and Epigenetics
16 - 18 Feb 2026 at MPI for Molecular Genetics, Berlin
with support by the Weizmann Institute for Science.
Early bird registration until 30 Sep - register now👇
www.molgen.mpg.de/embryo2026
16 - 18 Feb 2026 at MPI for Molecular Genetics, Berlin
with support by the Weizmann Institute for Science.
Early bird registration until 30 Sep - register now👇
www.molgen.mpg.de/embryo2026
Reposted by Babraham Institute
Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social
So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063
dx.doi.org/10.1111/imr.70063
Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers
Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...
dx.doi.org
September 25, 2025 at 7:53 PM
Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social
Reposted by Babraham Institute
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
tinyurl.com
September 19, 2025 at 10:53 AM
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
Reposted by Babraham Institute
This #TrainingTuesday why not check out our recently scheduled dates for the autumn term
#Bioinformatics #ComputationalBiology #ECRchat
www.bioinformatics.babraham.ac.uk/cgi-bin/publ...
@babrahaminst.bsky.social
#Bioinformatics #ComputationalBiology #ECRchat
www.bioinformatics.babraham.ac.uk/cgi-bin/publ...
@babrahaminst.bsky.social
a man with a mustache wearing a black hat and a blue shirt
ALT: a man with a mustache wearing a black hat and a blue shirt
media.tenor.com
September 23, 2025 at 8:40 AM
This #TrainingTuesday why not check out our recently scheduled dates for the autumn term
#Bioinformatics #ComputationalBiology #ECRchat
www.bioinformatics.babraham.ac.uk/cgi-bin/publ...
@babrahaminst.bsky.social
#Bioinformatics #ComputationalBiology #ECRchat
www.bioinformatics.babraham.ac.uk/cgi-bin/publ...
@babrahaminst.bsky.social