Ahmet O. Ceceli
@aoceceli.bsky.social
Instructor @ Mt. Sinai. Studying the neuroscience of addiction, reward, habits, and some related things with NIDA K99. Also makes a mean pizza.
Reposted by Ahmet O. Ceceli
We have at least TWO postdoctoral fellowship openings on our @unm.edu @casaa.bsky.social T32 NIAAA Training Grant, best consideration date for applications is Nov 15 2025. Join our phenomenal community and enjoy incredible quality of life in beautiful New Mexico. casaa.unm.edu/training/ins...
Application Process ::
Center on Alcohol, Substance use, And Addictions (CASAA) | The University of New Mexico
casaa.unm.edu
November 5, 2025 at 10:30 PM
We have at least TWO postdoctoral fellowship openings on our @unm.edu @casaa.bsky.social T32 NIAAA Training Grant, best consideration date for applications is Nov 15 2025. Join our phenomenal community and enjoy incredible quality of life in beautiful New Mexico. casaa.unm.edu/training/ins...
Excited to share our new paper in @pnas.org!!
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
The synergy of methylphenidate- and reconsolidation-based extinction normalizes ventromedial prefrontal function in drug addiction | PNAS
Drug-related memories can hinder abstinence goals in drug addiction. Promoting nondrugmemories
via ventromedial prefrontal cortex (vmPFC)- and amyg...
www.pnas.org
November 4, 2025 at 10:20 PM
Excited to share our new paper in @pnas.org!!
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
Reposted by Ahmet O. Ceceli
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
October 30, 2025 at 3:21 PM
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
Reposted by Ahmet O. Ceceli
Our new paper is out! It offers a tool to assess collinearity impact on contrast estimates
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
Unintended bias in the pursuit of collinearity solutions in fMRI analysis
Abstract. In task functional magnetic resonance imaging (fMRI), collinearity between task regressors in time series models may impact power. When collinearity is identified after data collection, rese...
direct.mit.edu
October 29, 2025 at 7:13 PM
Our new paper is out! It offers a tool to assess collinearity impact on contrast estimates
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
Reposted by Ahmet O. Ceceli
New paper out in cognition with @arikahn.bsky.social, @nathanieldaw.bsky.social, Cate Hartley, and @katenuss.bsky.social !!
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
Children leverage predictive representations for flexible, value-guided choice
By harnessing a mental model of how the world works, learners can make flexible choices in changing environments. However, while children and adolesce…
www.sciencedirect.com
October 15, 2025 at 10:52 AM
New paper out in cognition with @arikahn.bsky.social, @nathanieldaw.bsky.social, Cate Hartley, and @katenuss.bsky.social !!
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
Reposted by Ahmet O. Ceceli
Really interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine:
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
October 14, 2025 at 11:05 AM
Really interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine:
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
Reposted by Ahmet O. Ceceli
Motivations are like emotions about (what we know about) possible outcomes. Sometimes incentives spur urgency to act, other times to comprehend. Neuromodulatory systems reflect these motivational moods and shape memories. Out now w @jiahou-poh.bsky.social!
www.annualreviews.org/content/jour...
www.annualreviews.org/content/jour...
Motivation as Neural Context for Adaptive Learning and Memory Formation
Our memories shape our perception of the world and guide adaptive behavior. Rather than a veridical record of experiences, memory is selective. An accumulating body of work suggests that motivational ...
www.annualreviews.org
October 13, 2025 at 4:39 AM
Motivations are like emotions about (what we know about) possible outcomes. Sometimes incentives spur urgency to act, other times to comprehend. Neuromodulatory systems reflect these motivational moods and shape memories. Out now w @jiahou-poh.bsky.social!
www.annualreviews.org/content/jour...
www.annualreviews.org/content/jour...
Reposted by Ahmet O. Ceceli
Excited to share recent collaborative work led by Hayley Thorpe published in Molecular Psychiatry: Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals www.nature.com/articles/s41...
Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals - Molecular Psychiatry
Molecular Psychiatry - Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals
www.nature.com
October 13, 2025 at 12:41 PM
Excited to share recent collaborative work led by Hayley Thorpe published in Molecular Psychiatry: Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals www.nature.com/articles/s41...
Reposted by Ahmet O. Ceceli
Using neuroimaging, @mountsinainyc.bsky.social's Dr. Rita Z. Goldstein, et al. simultaneously examine sex differences & hormonal effects on brain responses to drug cues, and their down-regulation thru cognitive reappraisal, in subjects w/ #SubstanceUseDisorders👉
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
October 8, 2025 at 12:57 PM
Using neuroimaging, @mountsinainyc.bsky.social's Dr. Rita Z. Goldstein, et al. simultaneously examine sex differences & hormonal effects on brain responses to drug cues, and their down-regulation thru cognitive reappraisal, in subjects w/ #SubstanceUseDisorders👉
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Ahmet O. Ceceli
Reposted by Ahmet O. Ceceli
Excited to finally share this collaborative effort led by Philip Boone, Michael Talkowski and @abepalmer.bsky.social!
Aberrant recursive splicing in a human disease locus https://www.biorxiv.org/content/10.1101/2025.08.14.666599v1
August 15, 2025 at 3:23 PM
Excited to finally share this collaborative effort led by Philip Boone, Michael Talkowski and @abepalmer.bsky.social!
Reposted by Ahmet O. Ceceli
I will be interviewing for a clinical psychology PhD student in the Precision Psychopathology + Dynamic Immunopsychiatry Lab this interview cycle.
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Precision Psychopathology + Dynamic Immunopsychiatry Lab – University of Pennsylvania, Department of Psychology
share.google
August 7, 2025 at 11:23 AM
I will be interviewing for a clinical psychology PhD student in the Precision Psychopathology + Dynamic Immunopsychiatry Lab this interview cycle.
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Overwhelmed (in the best way!), speechless, and many other adjectives..Thank you, @bbrfoundation.bsky.social for propelling my research in addiction neuroscience with the 2025 Young Investigator Award + thanks as always to @narcatms.bsky.social and Mount Sinai for the unwavering support!
August 6, 2025 at 2:49 PM
Overwhelmed (in the best way!), speechless, and many other adjectives..Thank you, @bbrfoundation.bsky.social for propelling my research in addiction neuroscience with the 2025 Young Investigator Award + thanks as always to @narcatms.bsky.social and Mount Sinai for the unwavering support!
Reposted by Ahmet O. Ceceli
Neat registered report from @mattmattoni.bsky.social @dvsmith.bsky.social @mindimager.bsky.social and @olinotom.bsky.social diving into the tension between nomothetic (group-level) v. idiographic (individual specific) in functional connectivity models.
#Neuroskyence
direct.mit.edu/imag/article...
#Neuroskyence
direct.mit.edu/imag/article...
Functional Connectivity Heterogeneity and Consequences for Clinical and Cognitive Prediction
AbstractFunctional connectivity is frequently used to assess dynamic brain functioning and predict individual differences in behavioral outcomes, such as psychopathology. Inferences from functional co...
direct.mit.edu
July 27, 2025 at 9:36 PM
Neat registered report from @mattmattoni.bsky.social @dvsmith.bsky.social @mindimager.bsky.social and @olinotom.bsky.social diving into the tension between nomothetic (group-level) v. idiographic (individual specific) in functional connectivity models.
#Neuroskyence
direct.mit.edu/imag/article...
#Neuroskyence
direct.mit.edu/imag/article...
Reposted by Ahmet O. Ceceli
I’m looking for a postdoc to join me at UCSD, ideally a clinical psychologist PhD who can deliver mindfulness interventions as well as write papers and do analyses. I have one of the world’s largest psychophysiology datasets of opioid misuse, OUD, & chronic pain. Competitive salary. DM or email.
July 27, 2025 at 8:15 PM
I’m looking for a postdoc to join me at UCSD, ideally a clinical psychologist PhD who can deliver mindfulness interventions as well as write papers and do analyses. I have one of the world’s largest psychophysiology datasets of opioid misuse, OUD, & chronic pain. Competitive salary. DM or email.
Reposted by Ahmet O. Ceceli
This will change everything!
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
July 27, 2025 at 10:38 AM
This will change everything!
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
Reposted by Ahmet O. Ceceli
Ok, reinforcement learning fans: RL is great, but what do we do when there's no obvious reward from the environment? What about perfecting a golf swing or a foxtrot or a musical performance? We may have an answer. A tale of 🐦 🎶 + 🧠. 🧵1/ #bioacoustics #prattle 💬 #neuroai #compneuro
I am happy to share our new preprint! In this work, we proposed a theory about how zebra finches bootstrap their error signals for self-guided RL via predictive coding 👇 www.biorxiv.org/content/10.1...
Correctness is its own reward: bootstrapping error signals in self-guided reinforcement learning
Reinforcement learning (RL) offers a compelling account of how agents learn complex behaviors by trial and error, yet RL is predicated on the existence of a reward function provided by the agent's env...
www.biorxiv.org
July 24, 2025 at 2:29 PM
Ok, reinforcement learning fans: RL is great, but what do we do when there's no obvious reward from the environment? What about perfecting a golf swing or a foxtrot or a musical performance? We may have an answer. A tale of 🐦 🎶 + 🧠. 🧵1/ #bioacoustics #prattle 💬 #neuroai #compneuro
Reposted by Ahmet O. Ceceli
In an MRI study with 45 participants using deep-learning models, hippocampal activity was predictive of experiential choices, such as choosing a song to listen to. For choices involving risk, the ventral striatum and insula were active. In PNAS: www.pnas.org/doi/10.1073/...
July 25, 2025 at 5:57 PM
In an MRI study with 45 participants using deep-learning models, hippocampal activity was predictive of experiential choices, such as choosing a song to listen to. For choices involving risk, the ventral striatum and insula were active. In PNAS: www.pnas.org/doi/10.1073/...
Reposted by Ahmet O. Ceceli
Online #fMRI course coming up August 6-8!
3-day intensive with lectures and hands-on analysis for all skill levels. #SPM, #ICA, #DataScience with @vcalhoun.bsky.social and Kent Kiehl. We love teaching this course and meeting students from all areas! Info+Reg here:
sites.google.com/dartmouth.ed...
3-day intensive with lectures and hands-on analysis for all skill levels. #SPM, #ICA, #DataScience with @vcalhoun.bsky.social and Kent Kiehl. We love teaching this course and meeting students from all areas! Info+Reg here:
sites.google.com/dartmouth.ed...
fMRI Course
Instructors
sites.google.com
July 23, 2025 at 6:24 PM
Online #fMRI course coming up August 6-8!
3-day intensive with lectures and hands-on analysis for all skill levels. #SPM, #ICA, #DataScience with @vcalhoun.bsky.social and Kent Kiehl. We love teaching this course and meeting students from all areas! Info+Reg here:
sites.google.com/dartmouth.ed...
3-day intensive with lectures and hands-on analysis for all skill levels. #SPM, #ICA, #DataScience with @vcalhoun.bsky.social and Kent Kiehl. We love teaching this course and meeting students from all areas! Info+Reg here:
sites.google.com/dartmouth.ed...
A colossal effort from the NARC lab: we reviewed the recent advances in drug addiction research from the lens of the impaired response inhibition and salience attribution model. A one stop shop for theory, severity, recovery, and novel directions.
osf.io/preprints/ps...
osf.io/preprints/ps...
OSF
osf.io
July 22, 2025 at 2:21 AM
A colossal effort from the NARC lab: we reviewed the recent advances in drug addiction research from the lens of the impaired response inhibition and salience attribution model. A one stop shop for theory, severity, recovery, and novel directions.
osf.io/preprints/ps...
osf.io/preprints/ps...
Super excited to contribute to this book with our chapter "Enhancing Ecological Validity in Habit Research via Naturalistic Methods" (with Elizabeth Tricomi). Thanks, @dvsmith.bsky.social, @thepsychologist.bsky.social, and @dfareri.bsky.social for organizing!
osf.io/preprints/ps...
osf.io/preprints/ps...
July 19, 2025 at 3:59 AM
Super excited to contribute to this book with our chapter "Enhancing Ecological Validity in Habit Research via Naturalistic Methods" (with Elizabeth Tricomi). Thanks, @dvsmith.bsky.social, @thepsychologist.bsky.social, and @dfareri.bsky.social for organizing!
osf.io/preprints/ps...
osf.io/preprints/ps...
Reposted by Ahmet O. Ceceli
Changes in Model-Based and Model-Free Control Prospectively Predict Drinking Trajectories in Young Men www.biologicalpsychiatryjournal.com/article/S000...
Changes in Model-Based and Model-Free Control Prospectively Predict Drinking Trajectories in Young Men
Expanding our previous findings that model-based/model-free (MB/MF) control—often
conceptualized as goal-directed and habitual behavior—at age 18 is associated with
alcohol drinking trajectories over ...
www.biologicalpsychiatryjournal.com
July 18, 2025 at 6:29 PM
Changes in Model-Based and Model-Free Control Prospectively Predict Drinking Trajectories in Young Men www.biologicalpsychiatryjournal.com/article/S000...
Reposted by Ahmet O. Ceceli
Challenging the status quo: A guide to open and reproducible neuroimaging for early career researchers direct.mit.edu/imag/article...
July 18, 2025 at 2:55 PM
Challenging the status quo: A guide to open and reproducible neuroimaging for early career researchers direct.mit.edu/imag/article...
Reposted by Ahmet O. Ceceli
9/ Check out the actual study for many more analyses, e.g., phenotypic variation, scan parameters, signal to noise ratio, etc! doi.org/10.1038/s415...
Thank you to the editor @meharpist.bsky.social and anonymous reviewers for the many helpful suggestions, which greatly improved the study.
Thank you to the editor @meharpist.bsky.social and anonymous reviewers for the many helpful suggestions, which greatly improved the study.
Longer scans boost prediction and cut costs in brain-wide association studies - Nature
Although the number of participants is important for phenotypic prediction accuracy in brain-wide association studies using functional MRI, scanning for at least 30 min offers the greatest cost effect...
doi.org
July 17, 2025 at 1:36 AM
9/ Check out the actual study for many more analyses, e.g., phenotypic variation, scan parameters, signal to noise ratio, etc! doi.org/10.1038/s415...
Thank you to the editor @meharpist.bsky.social and anonymous reviewers for the many helpful suggestions, which greatly improved the study.
Thank you to the editor @meharpist.bsky.social and anonymous reviewers for the many helpful suggestions, which greatly improved the study.