Sarah Yip
@yiplab.bsky.social
Director, Yale Imaging & Psychopharmacology (YIP), Assoc Prof in Psychiatry & Child Study, addiction, mood, neuroimaging, tries to predict clinical stuff
Pinned
Sarah Yip
@yiplab.bsky.social
· 15d
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
Reposted by Sarah Yip
Happy New Preprint Friday!* Thrilled to share new results in collab with Sarah Lichenstein & @yiplab.bsky.social showing our brain's functional connections reflect the environments we grow up in!
tinyurl.com/exposomeConnectivity
#neuroskyence #PsychSciSky #DevPsy #cognition
*can this be a thing??
tinyurl.com/exposomeConnectivity
#neuroskyence #PsychSciSky #DevPsy #cognition
*can this be a thing??
November 14, 2025 at 1:40 PM
Happy New Preprint Friday!* Thrilled to share new results in collab with Sarah Lichenstein & @yiplab.bsky.social showing our brain's functional connections reflect the environments we grow up in!
tinyurl.com/exposomeConnectivity
#neuroskyence #PsychSciSky #DevPsy #cognition
*can this be a thing??
tinyurl.com/exposomeConnectivity
#neuroskyence #PsychSciSky #DevPsy #cognition
*can this be a thing??
Amazing opportunity to work at the intersection of complex clinical psychiatry and advanced neuroimaging research!!!
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
November 11, 2025 at 11:36 PM
Amazing opportunity to work at the intersection of complex clinical psychiatry and advanced neuroimaging research!!!
Reposted by Sarah Yip
Been thinking for a few years about what I call the *replication ceiling*: the maximum replicability of an effect given constraints in data in which replication takes place (power, measurement error, sampling variability, etc). This leads to a maximum theoretical replicability which can be achieved.
November 5, 2025 at 3:09 AM
Been thinking for a few years about what I call the *replication ceiling*: the maximum replicability of an effect given constraints in data in which replication takes place (power, measurement error, sampling variability, etc). This leads to a maximum theoretical replicability which can be achieved.
Reposted by Sarah Yip
Take a look at our paper! Led by @francimandi.bsky.social in the Lake lab: "Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice" !!!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice
Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...
www.biorxiv.org
October 31, 2025 at 4:39 PM
Take a look at our paper! Led by @francimandi.bsky.social in the Lake lab: "Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice" !!!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sarah Yip
Really interesting, brief ideas paper. Clearly relevant to treatment research-- the mechanism by which you leave an illness state is unlikely to just be the opposite of the mechanism by which you entered it (can see how this might apply to e.g. SSRIs in depression).
Thrilled to share a new paper in @jamapsychiatry.com on path asymmetry in complex dynamic systems of psychopathology! jamanetwork.com/journals/jam...
With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳
With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳
Path Asymmetry in Complex Dynamic Systems of Psychopathology
This article illustrates the assumption of path symmetry in current theories of psychopathology and calls for the development of dynamical systems of mental illness that incorporate asymmetry.
jamanetwork.com
October 31, 2025 at 11:09 AM
Really interesting, brief ideas paper. Clearly relevant to treatment research-- the mechanism by which you leave an illness state is unlikely to just be the opposite of the mechanism by which you entered it (can see how this might apply to e.g. SSRIs in depression).
Reposted by Sarah Yip
Check out the latest work from this superstar team to learn how you can go from big data to small data with transfer learning to advance precision psychiatry!
🧠
🧠
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
October 30, 2025 at 4:16 PM
Check out the latest work from this superstar team to learn how you can go from big data to small data with transfer learning to advance precision psychiatry!
🧠
🧠
Reposted by Sarah Yip
Anybody else worried that because of the long standing Republican war on SNAP people are going to experience painful hunger. Lets do something. @nanopharmnc.bsky.social and i are going to donate to some local nc food banks. Join us! Gonna match up to $500.
October 30, 2025 at 11:20 PM
Anybody else worried that because of the long standing Republican war on SNAP people are going to experience painful hunger. Lets do something. @nanopharmnc.bsky.social and i are going to donate to some local nc food banks. Join us! Gonna match up to $500.
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
October 30, 2025 at 3:21 PM
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
Reposted by Sarah Yip
😅
thrilled!! but speaking after @monicarosenb.bsky.social ??? that's too tough to follow
October 30, 2025 at 1:17 AM
😅
Reposted by Sarah Yip
Interested in the maternal brain and addiction? @yiplab.bsky.social and I are hiring a postdoc to work on our study examining psychosocial and neural markers of stress during the perinatal period in moms receiving treatment for OUD. See link for more details: postdocs.yale.edu/posts/2025-1...
Postdoctoral Associate Position — Child Study Center, Yale School of Medicine — The BABL Lab
Title of the Position: Postdoctoral Associate
postdocs.yale.edu
October 20, 2025 at 11:16 PM
Interested in the maternal brain and addiction? @yiplab.bsky.social and I are hiring a postdoc to work on our study examining psychosocial and neural markers of stress during the perinatal period in moms receiving treatment for OUD. See link for more details: postdocs.yale.edu/posts/2025-1...
Reposted by Sarah Yip
New paper in Imaging Neuroscience by Sam Laxer, Ravi S. Menon, et al:
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
doi.org/10.1162/IMAG...
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
doi.org/10.1162/IMAG...
October 11, 2025 at 1:35 PM
New paper in Imaging Neuroscience by Sam Laxer, Ravi S. Menon, et al:
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
doi.org/10.1162/IMAG...
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
doi.org/10.1162/IMAG...
Reposted by Sarah Yip
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
September 19, 2025 at 8:37 PM
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
New paper from @annierhcheng.bsky.social
using data from IMAGEN and ABCD she identifies distinct signatures of impulsivity and negative affect in youth that uniquely overlap with a neuromarker of risky alcohol use
#development #equifinality #abcd #connectome
www.nature.com/articles/s41...
using data from IMAGEN and ABCD she identifies distinct signatures of impulsivity and negative affect in youth that uniquely overlap with a neuromarker of risky alcohol use
#development #equifinality #abcd #connectome
www.nature.com/articles/s41...
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth - Molecular Psychiatry
Molecular Psychiatry - Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth
www.nature.com
September 27, 2025 at 2:35 PM
New paper from @annierhcheng.bsky.social
using data from IMAGEN and ABCD she identifies distinct signatures of impulsivity and negative affect in youth that uniquely overlap with a neuromarker of risky alcohol use
#development #equifinality #abcd #connectome
www.nature.com/articles/s41...
using data from IMAGEN and ABCD she identifies distinct signatures of impulsivity and negative affect in youth that uniquely overlap with a neuromarker of risky alcohol use
#development #equifinality #abcd #connectome
www.nature.com/articles/s41...
Reposted by Sarah Yip
The Biological Psychiatry family of journals is now officially on Bluesky!
Follow us for the latest research in psychiatric neuroscience, cognitive neuroimaging, and global open science from our three leading journals.
Follow us for the latest research in psychiatric neuroscience, cognitive neuroimaging, and global open science from our three leading journals.
September 25, 2025 at 9:36 AM
The Biological Psychiatry family of journals is now officially on Bluesky!
Follow us for the latest research in psychiatric neuroscience, cognitive neuroimaging, and global open science from our three leading journals.
Follow us for the latest research in psychiatric neuroscience, cognitive neuroimaging, and global open science from our three leading journals.
Reposted by Sarah Yip
A fresh, new @npp-journal.bsky.social paper from @yiplab.bsky.social & @lester-rodriguez.bsky.social is out now 👇
Massive congrats to @lester-rodriguez.bsky.social for his 1st (of many!) 1st authored paper!!!
Identification and external replication of a neuromarker of subjective drug effects to acute methamphetamine (vs placebo)!!!
nature.com/articles/s41...
@npp-journal.bsky.social
Identification and external replication of a neuromarker of subjective drug effects to acute methamphetamine (vs placebo)!!!
nature.com/articles/s41...
@npp-journal.bsky.social
Connectome-based encoding of subjective drug responses to acute oral methamphetamine - Neuropsychopharmacology
Neuropsychopharmacology - Connectome-based encoding of subjective drug responses to acute oral methamphetamine
nature.com
August 27, 2025 at 7:32 PM
A fresh, new @npp-journal.bsky.social paper from @yiplab.bsky.social & @lester-rodriguez.bsky.social is out now 👇
Massive congrats to @lester-rodriguez.bsky.social for his 1st (of many!) 1st authored paper!!!
Identification and external replication of a neuromarker of subjective drug effects to acute methamphetamine (vs placebo)!!!
nature.com/articles/s41...
@npp-journal.bsky.social
Identification and external replication of a neuromarker of subjective drug effects to acute methamphetamine (vs placebo)!!!
nature.com/articles/s41...
@npp-journal.bsky.social
Connectome-based encoding of subjective drug responses to acute oral methamphetamine - Neuropsychopharmacology
Neuropsychopharmacology - Connectome-based encoding of subjective drug responses to acute oral methamphetamine
nature.com
August 27, 2025 at 6:16 PM
Massive congrats to @lester-rodriguez.bsky.social for his 1st (of many!) 1st authored paper!!!
Identification and external replication of a neuromarker of subjective drug effects to acute methamphetamine (vs placebo)!!!
nature.com/articles/s41...
@npp-journal.bsky.social
Identification and external replication of a neuromarker of subjective drug effects to acute methamphetamine (vs placebo)!!!
nature.com/articles/s41...
@npp-journal.bsky.social
Reposted by Sarah Yip
I'm thrilled that my lab at NYU is now supported by an NIH MIRA grant! I'm looking to hire 1-2 senior lab members (outstanding postdoc candidates or experienced staff scientists) with expertise in computational or statistical methods in human genetics or genomics. Please share!
July 25, 2025 at 8:29 PM
I'm thrilled that my lab at NYU is now supported by an NIH MIRA grant! I'm looking to hire 1-2 senior lab members (outstanding postdoc candidates or experienced staff scientists) with expertise in computational or statistical methods in human genetics or genomics. Please share!
Reposted by Sarah Yip
As chair of the @acnporg.bsky.social Global Outreach Committee, I am happy to answer any questions about the Global Scholarship! Please share with your networks! Excellent opportunity to attend what might be the best science meeting in this space!
The ACNP Global Scholarship Application link is OPEN! The ACNP 64th Annual Meeting is January 12-15, 2026, in Nassau, Bahamas. The deadline to apply is August 15, 2025, at 5:00pm Central. Don’t miss out! #ACNP2026 Click here for more info: tinyurl.com/j8a9zybu
July 24, 2025 at 11:31 PM
As chair of the @acnporg.bsky.social Global Outreach Committee, I am happy to answer any questions about the Global Scholarship! Please share with your networks! Excellent opportunity to attend what might be the best science meeting in this space!
Reposted by Sarah Yip
Excited to share our latest preprint looking at the neuroanatomical basis of impulsivity in youth! 🧠
Neuroanatomy Reflects Individual Variability In Impulsivity in Youth
Individual differences in neural circuits underlying emotional regulation, motivation, and decision-making are implicated in many psychiatric illnesses. Interindividual variability in these circuits m...
www.biorxiv.org
April 24, 2025 at 11:53 AM
Excited to share our latest preprint looking at the neuroanatomical basis of impulsivity in youth! 🧠
Reposted by Sarah Yip
FYI, if you want to be prepared to apply for the next ABCD Study data release, prepare for these new NIST security requirements 🧠: @ohbmofficial.bsky.social abcdstudy.org/scientists/d...
Data Sharing - ABCD Study
abcdstudy.org
March 31, 2025 at 5:53 PM
FYI, if you want to be prepared to apply for the next ABCD Study data release, prepare for these new NIST security requirements 🧠: @ohbmofficial.bsky.social abcdstudy.org/scientists/d...
Reposted by Sarah Yip
Computational Phenotyping of Effort-Based Decision Making in Unmedicated Adults with Remitted Depression www.sciencedirect.com/science/arti...
February 27, 2025 at 4:23 AM
Computational Phenotyping of Effort-Based Decision Making in Unmedicated Adults with Remitted Depression www.sciencedirect.com/science/arti...
Reposted by Sarah Yip
Present your great work at #CPConf25 and join us in Tübingen - poster abstract submission now open!
Poster submissions for the Computational Psychiatry Conference 2025 in Tübingen are now open. Deadline is 7th February. Symposium submissions are open until 15th January. www.cpconf.org. Please RB.
Computational Psychiatry Conference
Tübingen, Germany (July 14-16, 2025)
www.cpconf.org
January 10, 2025 at 7:04 PM
Present your great work at #CPConf25 and join us in Tübingen - poster abstract submission now open!
Reposted by Sarah Yip
📣 Attn researchers interested in movie fcMRI x reliability! Glad to have been part of this work led by @halleeshearer.bsky.social & @vanderlab.bsky.social
Great work by @halleeshearer.bsky.social in her first first-author paper. With 🎀 shiny app 🎀 to explore how FC reliability fares ACROSS DIFFERENT movies versus rest, region-by-region. Thanks @sneuroble.bsky.social @tingsterx.bsky.social @ninetlab.bsky.social for 👍 collab.
doi.org/10.1162/imag...
doi.org/10.1162/imag...
January 4, 2025 at 12:27 AM
📣 Attn researchers interested in movie fcMRI x reliability! Glad to have been part of this work led by @halleeshearer.bsky.social & @vanderlab.bsky.social
Thrilled to kick 2025 off w/ this amazing tour de force led by @elvisha.bsky.social. Grateful to have been involved in this work highlighting the importance of considering #intersectionality in #neuroimaging @natureneuro.bsky.social
Thrilled to share our latest work on the importance of considering social identities in brain imaging research, now out in @natureneuro.bsky.social.
rdcu.be/d4XWM
rdcu.be/d4XWM
January 6, 2025 at 4:46 PM
Thrilled to kick 2025 off w/ this amazing tour de force led by @elvisha.bsky.social. Grateful to have been involved in this work highlighting the importance of considering #intersectionality in #neuroimaging @natureneuro.bsky.social