Annahita Delfan
anahitadelfan.bsky.social
Annahita Delfan
@anahitadelfan.bsky.social
Neuroscience
Reposted by Annahita Delfan
How can we make progress in developing a general model of neural computation rather than a series of disjointed models tied to specific experimental circumstances, ask Eva Dyer and @tyrellturing.bsky.social in the latest entry in our NeuroAI series.

www.thetransmitter.org/neuroai/acce...
Accepting “bitter lesson” and embracing brain’s complexity
To gain insight into complex neural data, we must move toward a data-driven regime, employing large models trained on vast amounts of data. Experts weigh in.
www.thetransmitter.org
March 26, 2025 at 4:12 PM
Reposted by Annahita Delfan
LLMs are about to make the problems in science visible. Let us be ready. This will make science better but we must make sure that what we will discover is taken the right way. An opportunity to do even more great things. open.substack.com/pub/kording/...
March 24, 2025 at 12:30 PM
Reposted by Annahita Delfan
Two cool papers out in Neuron today on memory.

1. Animals can be trained to activate specific remote memories at will:

www.cell.com/neuron/fullt...

2. Interactions between cortex and amygdala during reactivation in NREM sleep help enhance perceptual memories:

www.cell.com/neuron/fullt...

🧠📈 🧪
Closed-loop modulation of remote hippocampal representations with neurofeedback
Animal models of memory retrieval trigger retrieval with cues and measure retrieval using behavior. Coulter et al. developed a neurofeedback paradigm that rewards hippocampal activity patterns associa...
www.cell.com
March 20, 2025 at 3:12 PM
Reposted by Annahita Delfan
I am incredibly proud to share my first, first-author paper as a postdoc with @benhayden.bsky.social . How does the human hippocampus, known for encoding concepts, represent the meanings of words while listening to narrative speech?
www.biorxiv.org/content/10.1...
February 27, 2025 at 8:17 PM
Reposted by Annahita Delfan
𝗧𝗵𝗲 𝗽𝗿𝗼𝗯𝗹𝗲𝗺 𝘄𝗶𝘁𝗵 𝗔𝗜 𝗮𝗻𝗱 𝗿𝗲𝗹𝗮𝘁𝗲𝗱 𝘄𝗮𝘆𝘀 𝗼𝗳 𝘂𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱𝗶𝗻𝗴 𝗯𝗿𝗮𝗶𝗻 𝗮𝗻𝗱 𝗯𝗲𝗵𝗮𝘃𝗶𝗼𝗿: Lack of robustness to a qualitatively unknown future in an open world.
"Evolution and The Knightian Blindspot of Machine Learning".
Old lesson about AI from the 1970s that has been forgotten.
arxiv.org/abs/2501.13075
Evolution and The Knightian Blindspot of Machine Learning
This paper claims that machine learning (ML) largely overlooks an important facet of general intelligence: robustness to a qualitatively unknown future in an open world. Such robustness relates to Kni...
arxiv.org
January 24, 2025 at 10:55 PM
Reposted by Annahita Delfan
Quite the indictment of AI products: they are more appealing to people who don't understand how they work and see them as magical

The paper concludes: "businesses may benefit from targeting those with lower AI literacy" and "maintaining an aura of magic around AI" ✨

tinyurl.com/ynefd8zk
January 26, 2025 at 9:09 PM
Reposted by Annahita Delfan
As we attempt to build autonomous AI systems, we're discovering that agency—a capability we take for granted in animals—may be much more complex than we imagined, writes @tonyzador.bsky.social, in the latest essay in our NeuroAI series.

#neuroskyence

www.thetransmitter.org/neuroai/neur...
NeuroAI and the hidden complexity of agency
As we attempt to build autonomous AI systems, we’re discovering that a capability we take for granted in animals may be more complex than we imagined.
www.thetransmitter.org
February 5, 2025 at 2:23 PM
Reposted by Annahita Delfan
Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data.
🔗 www.nature.com/articles/s44...
🧪🧵
An initiative for living evidence synthesis in clinical psychedelic research - Nature Mental Health
Renewed interest in psychedelics as treatments for mental disorders has recently emerged, but substantial challenges remain in obtaining evidence from available data to inform clinical decision-making...
www.nature.com
January 10, 2025 at 4:12 PM
Reposted by Annahita Delfan
Is neuroscience research really working to understand the human brain? Or do we get lost in mouse cognition? I’ve asked myself this a lot since starting to work with human tissue. Our first Jonas Lab foray into untangling human hippocampal circuits is now online! www.cell.com/cell/fulltex... 1/a few
Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory
Human hippocampal CA3 networks use sparse and broad synaptic connectivity, and their recurrent synapses employ reliability, precision, and long integration times to enhance memory capacity. Thus, the human hippocampus is distinct from both rodent counterparts and human neocortical circuits.
www.cell.com
December 11, 2024 at 7:46 PM
Reposted by Annahita Delfan
🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap
December 3, 2024 at 2:58 PM
Reposted by Annahita Delfan
📯📯Photopharmacology and Switches communities📯📯

Here is a Feed reposting #molswitch #photoswitch #photopharma

bsky.app/profile/did:...

#chemsky #chembio #scisky 🧪
November 23, 2024 at 10:40 PM
Reposted by Annahita Delfan
105 cool microscopists in this starter pack, but I know there are more out there! I want to find more 45 to complete the list, can you help me? 🤓🔬
go.bsky.app/Aaf8sKT
November 21, 2024 at 6:30 PM
Reposted by Annahita Delfan
I created a genomics+bioinformatics starter pack. If I left you off, *please* reply and I'll add you! go.bsky.app/B5YYBfq
Genomics+Bioinformatics Starter Pack 🧬🖥️
Join the conversation
go.bsky.app
October 22, 2024 at 12:34 PM
Reposted by Annahita Delfan
I couldn't find a starter pack for the hematology community so I created one:
go.bsky.app/8K9pgxU
November 11, 2024 at 1:16 AM
Reposted by Annahita Delfan
Genomics, evolution, and more starter pack!

Help build community with this starter pack.

This list is currently incomplete. Want to be included? Reply and I will remedy that!
go.bsky.app/JjvzkWU
November 10, 2024 at 8:27 PM
Reposted by Annahita Delfan
November 17, 2024 at 12:25 PM
Reposted by Annahita Delfan
We've now filled one #Epigenetics, Chromatin and Gene regulation starter pack. Thanks for all the enthusiasm and support, if you'd like to be listed @raduzabet.bsky.social has been hard at work getting part II up and running:
go.bsky.app/SqLa3aw
November 25, 2024 at 3:50 PM
Reposted by Annahita Delfan
Wonderful to see the #immunology community growing here.

The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD
November 15, 2024 at 12:35 PM
Reposted by Annahita Delfan
We have quite a range of PhD projects this year, covering cryo-EM methods, bacteriology/bioenergetics, and infection/antibiotics/vaccines. Would really appreciate if people can RT and share with their teams!
November 29, 2024 at 11:55 AM
Reposted by Annahita Delfan
Everyone is worried about not being taken seriously, about being regarded as a crackpot, loose cannon, intellectual lightweight, dilettante, gadfly. I'm more worried about what happens when the spirit of subversion ebbs away. Everyone plows forward dutifully in their furrows.
November 27, 2024 at 3:14 PM
Reposted by Annahita Delfan
I have not seen a starter pack for the study of brain rhythms. So, here's a start.
go.bsky.app/A6zgHeE
November 26, 2024 at 5:52 PM
Reposted by Annahita Delfan
📯Chemical Biology Starter Pack #2: Probes Aficionadas👩‍🔬 go.bsky.app/DEjVGEn

as generalist ChemBio Pack #1
go.bsky.app/KLrTWoj is full

🚩Feed reposting #ChemBio: bsky.app/profile/trac...

🚩 #Photoswitch: bsky.app/profile/trac...

🚩 #FluorescenceFriday:
bsky.app/profile/trac...

#chemsky #realtimechem
November 23, 2024 at 11:50 PM
Reposted by Annahita Delfan
Super list Ellis! 📌📌 for #Chemsky. Thankyou!!

Lines 34-35 are doubled, should be:
Women in Chemical Biology (Probes & Tools) at bsky.app/starter-pack...
Chemical Biology (General) at bsky.app/starter-pack...

Will you add tabs Lists eg bsky.app/profile/did:... & Feeds eg bsky.app/profile/did:... ?
bsky.app
November 25, 2024 at 5:22 PM
Reposted by Annahita Delfan
Did some tidying up of the links for chemistry related starter packs, arranged loosely by subject area, and added who maintains the list so you know who to speak with if you'd like to be added!

tinyurl.com/ChemSkyStart...

#ChemSky #Chemistry #Chemists #StarterPacks 🧪
Bluesky Chem Starter Packs
tinyurl.com
November 25, 2024 at 2:01 PM