Andrew Payne
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andrewcpayne.bsky.social
Andrew Payne
@andrewcpayne.bsky.social
Current: E11 Bio. Previously: PhD MIT with Ed Boyden and Fei Chen. I develop technologies to accelerate biological research.
Reposted by Andrew Payne
Wonderful to collaborate with, and to support as an advisor, E11 Bio - and to announce PRISM, a technology for mapping brains in a self-correcting way, by barcoding neurons followed by expansion microscopy! Thread below by E11 Bio CEO Andrew Payne, with preprint at, www.biorxiv.org/content/10.1...
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism
October 2, 2025 at 6:43 PM
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism
October 1, 2025 at 2:16 PM
Congrats to Arlo Sheridan and Will Patton for releasing Volara, our first open-source library for scalable image processing, and also for a great technical writeup!
E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets! 🧪🔬

Volara features block-wise task abstractions, making scalable image processing more accessible, robust, and repeatable.

Read more: e11.bio/blog/volara
May 30, 2025 at 3:58 PM
@e11bio.bsky.social needs help to scale optical connectomics to humans and other mammals! Huge opportunity to have an impact on brain science as part of a world-class, mission-driven team. #hiring computational scientists at all levels to build data pipelines for brain microscopy images! 🧪
🚀 We are looking for Image Data Scientists to join our mission to advance connectomics towards whole brain scale for humans and other mammals (1/3) 🚀
February 5, 2025 at 9:37 PM
🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap
December 3, 2024 at 2:58 PM