E11 Bio
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e11bio.bsky.social
E11 Bio
@e11bio.bsky.social
A non-profit Focused Research Organization developing next-generation technology to accelerate neuroscience and improve human health. A part of Convergent Research.
E11 is thrilled to welcome Will Patton as our newest Machine Learning Scientist!! Before E11, Will worked at Janelia and contributed significantly to gunpowder, daisy and volara, three libraries that simplify training and application of machine learning to large microscopy volumes Welcome, Will!
October 10, 2025 at 6:20 PM
Reposted by E11 Bio
Proud of @e11bio.bsky.social's early progress here, and excited for so much more to come (that I've seen previews of as a FRO board member 😍).

Optics + expansion + barcoding + AI + molecules = beginning of infinity for scalable brain circuit mapping, with wide implications across science.
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism
October 1, 2025 at 2:28 PM
All the DNA from our preprint is available on @addgene.bsky.social!
New AAV tools from @e11bio.bsky.social! PRISM uses protein-tag barcodes for high-throughput reconstruction of neurons and other cell-labeling applications. https://twp.ai/4iruEB
October 1, 2025 at 3:52 PM
Reposted by E11 Bio
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism
October 1, 2025 at 2:16 PM
E11 is hiring a machine learning scientist to automate spatial reconstruction using our petabyte-scale microscopy data. Help us build the tools that will make neuronal mapping a reality and change the way we think about the brain.

lnkd.in/gxf_a4AB
September 12, 2025 at 9:10 PM
E11 Bio is seeking a creative and passionate spatial ‘omics scientist to co-develop next-generation technology for high-throughput barcoded connectomic imaging. Organized as a non-profit but operating like a startup, E11 is pursuing ambitious neuroscience to benefit society.

lnkd.in/gRHERZwZ
August 28, 2025 at 10:56 PM
E11 seeks a research associate with experience in fluorescence microscopy and tissue sectioning for our sample processing team. Work at a Focused Research Organization with great people, solid benefits, and tons of energy to complete the first mammalian connectome.

jobs.lever.co/convergentre...
Convergent Research - E11 Bio - Research Assistant, Biological Sample Processing
E11 Bio is on a mission to reach a whole-brain human connectome. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a r...
jobs.lever.co
August 18, 2025 at 7:56 PM
How to make frontier AI models safer and accelerate drug discovery with the connectome. We are featured in this
@ifp.bsky.social article by @adammarblestone.bsky.social & @andrewcpayne.bsky.social

ifp.org/mapping-the-...
Mapping the Brain for Alignment | IFP
How to map the mammalian brain’s connectome to solve fundamental problems in neuroscience, psychology, and AI robustness
ifp.org
August 12, 2025 at 1:39 AM
E11 welcomes Michelle Wu to our brain mapping team! Michelle just finished her BASc in Biomedical Engineering at University of Toronto. Her research experience includes UofT, the Broad Institute of MIT and Harvard, and a previous year with us at E11. We're super excited to have her back.
July 25, 2025 at 8:29 PM
This week we’re thrilled to welcome Victor Holmes to the E11 team as our new Chief of Staff!

Victor brings deep experience in scientific operations, project strategy, and team management. He’ll help build the connective tissue that supports our progress toward mammalian connectomics. Welcome!
July 22, 2025 at 10:27 PM
This summer we welcome Julia Lyudchik and Jakob Troidl to the team!

Julia got her PhD at ISTA developing light microscopy visualization and reconstruction methods: LIONESS, CATS & LICONN.

Jakob is a PhD candidate at Harvard University interested in data visualization and applied machine learning.
June 16, 2025 at 6:05 PM
We're excited to welcome Jeff Chen and JinYoung Lee to the team! 🎉

Both are University of Toronto undergrads joining us for a gap year. Jeff will work on barcode design and viral payloads, while JinYoung will focus on expansion microscopy and imaging.
June 10, 2025 at 4:49 PM
Reposted by E11 Bio
"Academic research groups and startups are essential drivers of scientific progress. But some projects, like the Hubble Space Telescope or the Human Genome Project, are too big for any one academic lab or loose consortium..."
Former MIT researchers advance a new model for innovation
Developed by former MIT researchers, focused research organizations (FROs) undertake large research efforts and have begun to contribute to scientific advances.
news.mit.edu
June 9, 2025 at 7:46 PM
E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets! 🧪🔬

Volara features block-wise task abstractions, making scalable image processing more accessible, robust, and repeatable.

Read more: e11.bio/blog/volara
May 29, 2025 at 3:29 PM
✨E11 Bio is hiring a Chief of Staff / Project Manager!

This unique role blends scientific project management with day-to-day operations—and gives you a front-row seat and bird’s-eye view as we advance the field of connectomics toward mammalian brains.

Job posting: jobs.lever.co/convergentre...
Convergent Research - E11 Bio - Chief of Staff / Project Manager
E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuro...
jobs.lever.co
May 7, 2025 at 8:24 PM
Our work in connectomics is featured in @asimovpress.bsky.social! We’re building new tools to map the brain with greater precision and scale!
Can we treat brain disorders by restoring neural connections?

For centuries, neuroscientists could only guess. But connectomics—a method seeking to create a 3D model of every neural connection in the brain—is moving closer to providing answers.

E11 Bio is at the forefront...🧵
February 9, 2025 at 7:02 PM
We're hiring! Join our team as an Image Data Scientist and help create stunning and impactful connectomic datasets! 🧠✨
🚀 We are looking for Image Data Scientists to join our mission to advance connectomics towards whole brain scale for humans and other mammals (1/3) 🚀
February 5, 2025 at 9:41 PM
Reposted by E11 Bio
🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap
December 3, 2024 at 2:58 PM