Amber Howell
@ambrains.bsky.social
Neuroscientist studying corticosubcortical circuitry in humans and NHP. Currently a postdoc at Rutgers; PhD at Yale
Reposted by Amber Howell
The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
November 11, 2025 at 4:50 PM
The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
Reposted by Amber Howell
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
November 11, 2025 at 3:48 PM
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
Reposted by Amber Howell
Holmes Lab + Parkes Lab had a great fall social a few weeks back!! Pottery painting (including an awesome brain-art mug by @ambrains.bsky.social 🧠). Thank you to our awesome mentors @avramholmes.bsky.social and @lindenmp.bsky.social for encouraging these great lab events! 💫
October 7, 2025 at 4:16 PM
Holmes Lab + Parkes Lab had a great fall social a few weeks back!! Pottery painting (including an awesome brain-art mug by @ambrains.bsky.social 🧠). Thank you to our awesome mentors @avramholmes.bsky.social and @lindenmp.bsky.social for encouraging these great lab events! 💫
Reposted by Amber Howell
Interesting approach that aligns mouse and human brain-wide data using transcriptomics and structural connectivity. I'm curious if anyone here has tried using it yet? #neuroskyence www.biorxiv.org/content/10.1... transbrain.readthedocs.io/en/latest/
TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice
Despite remarkable advances in whole-brain imaging technologies, the lack of quantitative approaches to bridge rodent preclinical and human studies remains a critical challenge. Here we present TransB...
www.biorxiv.org
October 15, 2025 at 4:29 PM
Interesting approach that aligns mouse and human brain-wide data using transcriptomics and structural connectivity. I'm curious if anyone here has tried using it yet? #neuroskyence www.biorxiv.org/content/10.1... transbrain.readthedocs.io/en/latest/
Reposted by Amber Howell
the climate's probably just changing for attention
September 29, 2025 at 9:51 AM
the climate's probably just changing for attention
Reposted by Amber Howell
Resting-State fMRI and the Risk of Overinterpretation: Noise, Mechanisms, and a Missing Rosetta Stone https://www.biorxiv.org/content/10.1101/2025.09.16.676611v1
September 19, 2025 at 9:15 PM
Resting-State fMRI and the Risk of Overinterpretation: Noise, Mechanisms, and a Missing Rosetta Stone https://www.biorxiv.org/content/10.1101/2025.09.16.676611v1
Reposted by Amber Howell
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
September 19, 2025 at 8:37 PM
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Reposted by Amber Howell
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Reposted by Amber Howell
Absolutely thrilled to share the 🌟 FIRST PAPER 🌟 from ACORN Lab! 🐿️ I’m beyond proud of all-star grad student @heatherarobinson.bsky.social for this review of “exposome” effects on neurodevelopment & cognition! Paper here rdcu.be/ezUqx & thread below 👇 /1
#neuroskyence #PsychSciSky #devsky #cogdev
#neuroskyence #PsychSciSky #devsky #cogdev
The effect of the “exposome” on developmental brain health and cognitive outcomes
Neuropsychopharmacology - The effect of the “exposome” on developmental brain health and cognitive outcomes
rdcu.be
August 8, 2025 at 4:22 PM
Absolutely thrilled to share the 🌟 FIRST PAPER 🌟 from ACORN Lab! 🐿️ I’m beyond proud of all-star grad student @heatherarobinson.bsky.social for this review of “exposome” effects on neurodevelopment & cognition! Paper here rdcu.be/ezUqx & thread below 👇 /1
#neuroskyence #PsychSciSky #devsky #cogdev
#neuroskyence #PsychSciSky #devsky #cogdev
Reposted by Amber Howell
🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘
www.biorxiv.org/content/10.1...
Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
www.biorxiv.org/content/10.1...
Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
May 30, 2025 at 7:47 PM
🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘
www.biorxiv.org/content/10.1...
Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
www.biorxiv.org/content/10.1...
Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
Reposted by Amber Howell
On behalf of Nicole Carr: new preprint from the Chand/Moore labs! High-resolution laminar recordings reveal structure-function relationships in monkey V1.
1/4
www.biorxiv.org/content/10.1...
1/4
www.biorxiv.org/content/10.1...
High–resolution laminar recordings reveal structure–function relationships in monkey V1
The relationship between the structural properties of diverse neuronal populations in the monkey primary visual cortex (V1) and their functional visual processing in vivo remains a critical knowledge ...
www.biorxiv.org
May 19, 2025 at 9:09 PM
On behalf of Nicole Carr: new preprint from the Chand/Moore labs! High-resolution laminar recordings reveal structure-function relationships in monkey V1.
1/4
www.biorxiv.org/content/10.1...
1/4
www.biorxiv.org/content/10.1...
Reposted by Amber Howell
Info theory offers powerful measures for capturing complexity & interaction among elements of a complex system, like the brain! 🧠 Here's our new unified reference for key info-theoretic time series measures ft. 📊 visuals, ➗equations, & 💬descriptions:
arxiv.org/abs/2505.13080
arxiv.org/abs/2505.13080
May 20, 2025 at 3:26 AM
Info theory offers powerful measures for capturing complexity & interaction among elements of a complex system, like the brain! 🧠 Here's our new unified reference for key info-theoretic time series measures ft. 📊 visuals, ➗equations, & 💬descriptions:
arxiv.org/abs/2505.13080
arxiv.org/abs/2505.13080
Reposted by Amber Howell
🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis.
Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3
www.medrxiv.org/content/10.1...
Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3
www.medrxiv.org/content/10.1...
May 12, 2025 at 1:09 AM
🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis.
Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3
www.medrxiv.org/content/10.1...
Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3
www.medrxiv.org/content/10.1...
Reposted by Amber Howell
Check out our new special issue on cognitive flexibility @coolscontrol.bsky.social: authors.elsevier.com/a/1l4vl8MqMi...
authors.elsevier.com
May 12, 2025 at 10:23 PM
Check out our new special issue on cognitive flexibility @coolscontrol.bsky.social: authors.elsevier.com/a/1l4vl8MqMi...
Reposted by Amber Howell
🧠 Check out the new preprint from Dr. Linden Parkes, Assistant Professor of Psychiatry at Rutgers Robert Wood Johnson Medical School and Core member of Rutgers Center for Advanced Human Brain Imaging Research (CAHBIR) and BHI! @lindenmp.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Inferring macroscopic intrinsic neural timescales using optimal control theory
The temporal evolution of brain activity relies on complex interactions within and between brain regions that are mediated by neurobiology and connectivity. To understand these interactions, many larg...
www.biorxiv.org
April 29, 2025 at 3:00 PM
🧠 Check out the new preprint from Dr. Linden Parkes, Assistant Professor of Psychiatry at Rutgers Robert Wood Johnson Medical School and Core member of Rutgers Center for Advanced Human Brain Imaging Research (CAHBIR) and BHI! @lindenmp.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Amber Howell
Excited to share the first major piece of work and preprint from my lab! Led by Jason Kim! 🥳🎉🤘
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
a man applauds with the words so proud of my team above him
ALT: a man applauds with the words so proud of my team above him
media.tenor.com
April 28, 2025 at 12:56 PM
Excited to share the first major piece of work and preprint from my lab! Led by Jason Kim! 🥳🎉🤘
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Amber Howell
The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes @avramholmes.bsky.social
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 16, 2025 at 3:29 PM
The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes @avramholmes.bsky.social
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
Reposted by Amber Howell
Future of #fMRI:
To make a meaningful contribution to neuroscience, fMRI must break out of its silo
www.thetransmitter.org/future-of-fm...
#neuropsychology #cognition
To make a meaningful contribution to neuroscience, fMRI must break out of its silo
www.thetransmitter.org/future-of-fm...
#neuropsychology #cognition
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 12, 2025 at 3:26 PM
Future of #fMRI:
To make a meaningful contribution to neuroscience, fMRI must break out of its silo
www.thetransmitter.org/future-of-fm...
#neuropsychology #cognition
To make a meaningful contribution to neuroscience, fMRI must break out of its silo
www.thetransmitter.org/future-of-fm...
#neuropsychology #cognition
Reposted by Amber Howell
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
doi.org
April 12, 2025 at 10:28 AM
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
Reposted by Amber Howell
The molecular and cellular basis of human brain lateralization. Latest paper from @holmeslab-bhi.bsky.social led by @loiclabache.bsky.social. @rutgersbhi.bsky.social, @cahbir.bsky.social
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
doi.org
April 12, 2025 at 12:29 PM
The molecular and cellular basis of human brain lateralization. Latest paper from @holmeslab-bhi.bsky.social led by @loiclabache.bsky.social. @rutgersbhi.bsky.social, @cahbir.bsky.social
Reposted by Amber Howell
Excellent preprint by a great team @loiclabache.bsky.social @sidchop.bsky.social @xi-hanzhang.bsky.social @avramholmes.bsky.social on the underpinnings of human brain lateralization: an Acetylcholine-Norepinephrine axis for functional lateralization + mitochondrial substrates & cellular correlates🧪
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
www.biorxiv.org
April 12, 2025 at 8:32 AM
Excellent preprint by a great team @loiclabache.bsky.social @sidchop.bsky.social @xi-hanzhang.bsky.social @avramholmes.bsky.social on the underpinnings of human brain lateralization: an Acetylcholine-Norepinephrine axis for functional lateralization + mitochondrial substrates & cellular correlates🧪
Reposted by Amber Howell
"To make a meaningful contribution to #neuroscience, #fMRI must break out of its silo."
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
Until recently, in-vivo brain imaging has largely been absent from… integrative efforts, limiting the opportunities to contribute our discoveries, theories or vision toward a comprehensive view of brain function, writes @avramholmes.bsky.social.
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 8, 2025 at 1:19 PM
"To make a meaningful contribution to #neuroscience, #fMRI must break out of its silo."
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
Reposted by Amber Howell
Until recently, in-vivo brain imaging has largely been absent from… integrative efforts, limiting the opportunities to contribute our discoveries, theories or vision toward a comprehensive view of brain function, writes @avramholmes.bsky.social.
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 8, 2025 at 1:15 PM
Until recently, in-vivo brain imaging has largely been absent from… integrative efforts, limiting the opportunities to contribute our discoveries, theories or vision toward a comprehensive view of brain function, writes @avramholmes.bsky.social.
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
Reposted by Amber Howell
🧠 Featured Insights! Dr. @avramholmes.bsky.social, Associate Prof of Psychiatry at RWJMS and Core Member of BHI & CAHBIR, shares insights on #fMRI and the need for integration across #neuroscience disciplines in @thetransmitter.bsky.social
www.thetransmitter.org/future-of-fm...
#neuroimaging
www.thetransmitter.org/future-of-fm...
#neuroimaging
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 8, 2025 at 3:51 PM
🧠 Featured Insights! Dr. @avramholmes.bsky.social, Associate Prof of Psychiatry at RWJMS and Core Member of BHI & CAHBIR, shares insights on #fMRI and the need for integration across #neuroscience disciplines in @thetransmitter.bsky.social
www.thetransmitter.org/future-of-fm...
#neuroimaging
www.thetransmitter.org/future-of-fm...
#neuroimaging
Reposted by Amber Howell
New paper in Imaging Neuroscience by Vaanathi Sundaresan, Anastasia Yendiki, et al:
Self-supervised segmentation and characterization of fiber bundles in anatomic tracing data
doi.org/10.1162/imag...
Self-supervised segmentation and characterization of fiber bundles in anatomic tracing data
doi.org/10.1162/imag...
March 28, 2025 at 9:10 PM
New paper in Imaging Neuroscience by Vaanathi Sundaresan, Anastasia Yendiki, et al:
Self-supervised segmentation and characterization of fiber bundles in anatomic tracing data
doi.org/10.1162/imag...
Self-supervised segmentation and characterization of fiber bundles in anatomic tracing data
doi.org/10.1162/imag...