Andrew Bland
@acbmd22.bsky.social
Med/Peds. Nephrology. Educator. Floinator. MBA and Masters of Data Science and Predictive Analytics
Reposted by Andrew Bland
This highlights the importance of stakeholder involvement and the impact of disease prevalence when evaluating AI tool effectiveness.
#EuropeanRadiology #RadSky #MedSky
🔗 https://buff.ly/4aMWy4G
#EuropeanRadiology #RadSky #MedSky
🔗 https://buff.ly/4aMWy4G
Implementing an AI algorithm in the clinical setting: a case study for the accuracy paradox - European Radiology
Objectives We report our experience implementing an algorithm for the detection of large vessel occlusion (LVO) for suspected stroke in the emergency setting, including its performance, and offer an…
buff.ly
February 13, 2025 at 8:00 AM
This highlights the importance of stakeholder involvement and the impact of disease prevalence when evaluating AI tool effectiveness.
#EuropeanRadiology #RadSky #MedSky
🔗 https://buff.ly/4aMWy4G
#EuropeanRadiology #RadSky #MedSky
🔗 https://buff.ly/4aMWy4G
Reposted by Andrew Bland
Contrary to popular- (ahem, cardiology bias)- opinion, it is unlikely that hypertension is causal of chronic kidney disease: academic.oup.com/ndt/advance-... #openaccess
Classic editorial this week from the #NephSky expert, Dr. Agarwal!!, 👀🤓🙏💛
Classic editorial this week from the #NephSky expert, Dr. Agarwal!!, 👀🤓🙏💛
Hypertensive nephropathy: revisiting the causal link between hypertension and kidney disease
Rajiv Agarwal; Hypertensive nephropathy: revisiting the causal link between hypertension and kidney disease, Nephrology Dialysis Transplantation, , gfaf014
academic.oup.com
February 5, 2025 at 4:06 PM
Contrary to popular- (ahem, cardiology bias)- opinion, it is unlikely that hypertension is causal of chronic kidney disease: academic.oup.com/ndt/advance-... #openaccess
Classic editorial this week from the #NephSky expert, Dr. Agarwal!!, 👀🤓🙏💛
Classic editorial this week from the #NephSky expert, Dr. Agarwal!!, 👀🤓🙏💛
Reposted by Andrew Bland
Great piece, this is what stuck with me: "The care I provided in the delivery room to ensure that this baby survived: 1.94 RVUs (code 99464)... Elsewhere in the hospital, if my physician colleagues perform 30 minutes of hair removal by electrolysis: 264.87 RVUs (code 17380)."
Everyone should read this piece: "What Is the Relative Value of a Baby?" | New England Journal of Medicine
@canadianpreemies.bsky.social @99nicu.bsky.social @ebneo.bsky.social
www.nejm.org/doi/full/10....
@canadianpreemies.bsky.social @99nicu.bsky.social @ebneo.bsky.social
www.nejm.org/doi/full/10....
What Is the Relative Value of a Baby? | NEJM
As she cares for a newborn who’s struggling to breathe, a neonatologist contemplates
how politics and power structures affect the availability of critical perinatal services
in the United States.
www.nejm.org
January 26, 2025 at 1:32 AM
Great piece, this is what stuck with me: "The care I provided in the delivery room to ensure that this baby survived: 1.94 RVUs (code 99464)... Elsewhere in the hospital, if my physician colleagues perform 30 minutes of hair removal by electrolysis: 264.87 RVUs (code 17380)."
Reposted by Andrew Bland
Proposed age-adjusted eGFR thresholds for CKD 👇
#Nephpearls #NephSky
eGFR 75 for ages <40 years
eGFR 60 for 40-65 years
eGFR 45 for >65 years
👉 link.springer.com/book/10.1007...
👉 pubmed.ncbi.nlm.nih.gov/31506289/
#Nephpearls #NephSky
eGFR 75 for ages <40 years
eGFR 60 for 40-65 years
eGFR 45 for >65 years
👉 link.springer.com/book/10.1007...
👉 pubmed.ncbi.nlm.nih.gov/31506289/
January 10, 2025 at 3:26 PM
Proposed age-adjusted eGFR thresholds for CKD 👇
#Nephpearls #NephSky
eGFR 75 for ages <40 years
eGFR 60 for 40-65 years
eGFR 45 for >65 years
👉 link.springer.com/book/10.1007...
👉 pubmed.ncbi.nlm.nih.gov/31506289/
#Nephpearls #NephSky
eGFR 75 for ages <40 years
eGFR 60 for 40-65 years
eGFR 45 for >65 years
👉 link.springer.com/book/10.1007...
👉 pubmed.ncbi.nlm.nih.gov/31506289/
Reposted by Andrew Bland
Endothelin receptor antagonists in chronic kidney disease | Nature Reviews Nephrology - goo.gl/alerts/D9gxoY #GoogleAlerts
Endothelin receptor antagonists in chronic kidney disease - Nature Reviews Nephrology
Endothelin-1 (ET-1) is a potent vasoactive peptide that is produced by various cell types of the kidney and regulates a variety of physiological processes. This Review describes the role of ET-1 in th...
goo.gl
December 7, 2024 at 9:35 PM
Endothelin receptor antagonists in chronic kidney disease | Nature Reviews Nephrology - goo.gl/alerts/D9gxoY #GoogleAlerts
Reposted by Andrew Bland
Not every day a leading US academic health system partners with @costplusdrugs.com, bypassing PBMs, to save drug costs for their patients
@pennmedicine.bsky.social + @mcuban.bsky.social
www.pennmedicine.org/news/news-re... a 1st-of-its-kind deal
@pennmedicine.bsky.social + @mcuban.bsky.social
www.pennmedicine.org/news/news-re... a 1st-of-its-kind deal
Penn Medicine partners with Mark Cuban’s Cost Plus Drugs
Penn Medicine has partnered with Mark Cuban's Cost Plus Drug Company through its innovative Cost Plus Marketplace in a strategic alliance that will allow Penn Medicine to secure the top 100 most frequ...
www.pennmedicine.org
December 7, 2024 at 8:32 PM
Not every day a leading US academic health system partners with @costplusdrugs.com, bypassing PBMs, to save drug costs for their patients
@pennmedicine.bsky.social + @mcuban.bsky.social
www.pennmedicine.org/news/news-re... a 1st-of-its-kind deal
@pennmedicine.bsky.social + @mcuban.bsky.social
www.pennmedicine.org/news/news-re... a 1st-of-its-kind deal
Reposted by Andrew Bland
December 4, 2024 at 5:22 AM
Reposted by Andrew Bland
Little discussed fact: Choosing to not “treat” high blood pressure makes you look like a wacko to the nurses and CRNAs/anesthesiologists in the real world where I practice
It requires lots of time, explanation, being present, and even documentation of your rationale
It requires lots of time, explanation, being present, and even documentation of your rationale
December 2, 2024 at 12:01 AM
Little discussed fact: Choosing to not “treat” high blood pressure makes you look like a wacko to the nurses and CRNAs/anesthesiologists in the real world where I practice
It requires lots of time, explanation, being present, and even documentation of your rationale
It requires lots of time, explanation, being present, and even documentation of your rationale
Reposted by Andrew Bland
Skytorial: Five pearls on olanzapine 😁
Between agitation and nausea/vomiting, olanzapine has a wide range of use.
Olanzapine is generally not a front-line agent (e.g., haloperidol or ondansetron often are). But sometimes, it really comes in clutch....
Between agitation and nausea/vomiting, olanzapine has a wide range of use.
Olanzapine is generally not a front-line agent (e.g., haloperidol or ondansetron often are). But sometimes, it really comes in clutch....
a man in a plaid shirt sits at a picnic table with the words " settle down " on the bottom
ALT: a man in a plaid shirt sits at a picnic table with the words " settle down " on the bottom
media.tenor.com
November 27, 2024 at 1:17 PM
Skytorial: Five pearls on olanzapine 😁
Between agitation and nausea/vomiting, olanzapine has a wide range of use.
Olanzapine is generally not a front-line agent (e.g., haloperidol or ondansetron often are). But sometimes, it really comes in clutch....
Between agitation and nausea/vomiting, olanzapine has a wide range of use.
Olanzapine is generally not a front-line agent (e.g., haloperidol or ondansetron often are). But sometimes, it really comes in clutch....
Reposted by Andrew Bland
ICYMI: A batch of the #CKD drug #cinacalcet has been recalled by the FDA. #drugrecall #kidneydisease
FDA Recalls CKD Drug Cinacalcet | Docwire News
The FDA issued a recall of a batch of Dr. Reddy’s Cinacalcet Tablets. Cinacalcet is a treatment for chronic kidney disease (CKD) and other conditions.
buff.ly
November 27, 2024 at 11:00 PM
ICYMI: A batch of the #CKD drug #cinacalcet has been recalled by the FDA. #drugrecall #kidneydisease
Reposted by Andrew Bland
journals.lww.com/cjasn/fullte...
Large sample , real world data .
Would want to know reasons for discontinuation . In our practice CKD3b,CKD4 patients hitting the panic button after GFR drop 3-4 ml even though they were counseled about a likely drop in the first three months or more.
Large sample , real world data .
Would want to know reasons for discontinuation . In our practice CKD3b,CKD4 patients hitting the panic button after GFR drop 3-4 ml even though they were counseled about a likely drop in the first three months or more.
Association of Kidney Function with Sodium-Glucose... : Clinical Journal of the American Society of Nephrology
LT2i discontinuation in patients with CKD may limit the cardiokidney benefits of SGLT2i in real-world practice.
Background
The effect of sodium-glucose co-transporter-2 inhibitors (SGLT2i) on cardi...
journals.lww.com
November 28, 2024 at 1:42 AM
journals.lww.com/cjasn/fullte...
Large sample , real world data .
Would want to know reasons for discontinuation . In our practice CKD3b,CKD4 patients hitting the panic button after GFR drop 3-4 ml even though they were counseled about a likely drop in the first three months or more.
Large sample , real world data .
Would want to know reasons for discontinuation . In our practice CKD3b,CKD4 patients hitting the panic button after GFR drop 3-4 ml even though they were counseled about a likely drop in the first three months or more.
Reposted by Andrew Bland
The water intake trial: www.nephjc.com/news/waterin... on #NephJC
Read the whole #Skytorial from @fperrywilson.bsky.social ⏬
Read the whole #Skytorial from @fperrywilson.bsky.social ⏬
November 28, 2024 at 12:00 AM
The water intake trial: www.nephjc.com/news/waterin... on #NephJC
Read the whole #Skytorial from @fperrywilson.bsky.social ⏬
Read the whole #Skytorial from @fperrywilson.bsky.social ⏬
Reposted by Andrew Bland
1/9
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
November 28, 2024 at 2:40 AM
1/9
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
Reposted by Andrew Bland
'A better understanding of the pathophysiology and intricacies of the RAAS in septic vasodilatory shock has led to using exogenous angiotensin II as a new drug to treat sepsis. The use of angiotensin II may improve outcomes' #critcaresky #emimcc #RAAS #renin
ccforum.biomedcentral.com/articles/10....
ccforum.biomedcentral.com/articles/10....
The renin–angiotensin–aldosterone-system in sepsis and its clinical modulation with exogenous angiotensin II - Critical Care
Dysregulation of the renin–angiotensin–aldosterone-system (RAAS) in sepsis is a complex and early phenomenon with a likely significant contribution to organ failure and patient outcomes. A better unde...
ccforum.biomedcentral.com
November 27, 2024 at 11:08 PM
'A better understanding of the pathophysiology and intricacies of the RAAS in septic vasodilatory shock has led to using exogenous angiotensin II as a new drug to treat sepsis. The use of angiotensin II may improve outcomes' #critcaresky #emimcc #RAAS #renin
ccforum.biomedcentral.com/articles/10....
ccforum.biomedcentral.com/articles/10....
Reposted by Andrew Bland
Honey, stop what you're doing, new hyponatremia research just dropped!
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia
This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.
jamanetwork.com
November 19, 2024 at 4:51 AM
Honey, stop what you're doing, new hyponatremia research just dropped!
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
Reposted by Andrew Bland
I'm a big fan of sequential nephron blockade, including diamox, which I have used successfully many times. But as a reminder, the VAST majority of patients w/ADHF can be successfully decongested with adequate loop diuretic doses and adding thiazides when necessary #medsky #cardiosky
November 18, 2024 at 11:39 PM
I'm a big fan of sequential nephron blockade, including diamox, which I have used successfully many times. But as a reminder, the VAST majority of patients w/ADHF can be successfully decongested with adequate loop diuretic doses and adding thiazides when necessary #medsky #cardiosky
Reposted by Andrew Bland
📖 KI #ISNFridaySelection: "Effects of dialysate K concentration of 3.0mEq/l with sodium zirconium cyclosilicate on dialysis-free days vs dialysate K concentration of 2.0mEq/l alone on rates of cardiac arrhythmias in HD pts w/hyperkalemia", presented @ #KidneyWk: www.kidney-internati... #NephSky
November 15, 2024 at 6:00 AM
📖 KI #ISNFridaySelection: "Effects of dialysate K concentration of 3.0mEq/l with sodium zirconium cyclosilicate on dialysis-free days vs dialysate K concentration of 2.0mEq/l alone on rates of cardiac arrhythmias in HD pts w/hyperkalemia", presented @ #KidneyWk: www.kidney-internati... #NephSky