Steven Mathern
@stevenmathern.bsky.social
#idsky #medsky #cardiosky #pocusky #pocus #CTOPCI #critcaresky #ViroSky #immunology #EmImCc #Epeeps #OMI #EKG #Impella #ECMO #TEER #TAVR #TD-ADR
Reposted by Steven Mathern
May 20, 2025 at 11:35 AM
Reposted by Steven Mathern
GOOD NEWS! Researchers have found that getting vaccinated against shingles- a painful and debilitating condition that can flare up years after infection from VZV- not only LOWERS the risk of infection, but can also PROTECT against dementia and REDUCE the risk of cardiovascular disease! 🧪🧵⬇️
May 15, 2025 at 4:01 PM
GOOD NEWS! Researchers have found that getting vaccinated against shingles- a painful and debilitating condition that can flare up years after infection from VZV- not only LOWERS the risk of infection, but can also PROTECT against dementia and REDUCE the risk of cardiovascular disease! 🧪🧵⬇️
Reposted by Steven Mathern
did you think that labetalol is a single drug?
nope
it’s actually a mixture of FOUR different drugs
RS, RR, SS, and SR-labetalol
and this is clinically relevant!
lets discuss why…
🧵 #1/3 #EMIMCC
nope
it’s actually a mixture of FOUR different drugs
RS, RR, SS, and SR-labetalol
and this is clinically relevant!
lets discuss why…
🧵 #1/3 #EMIMCC
May 11, 2025 at 4:45 PM
did you think that labetalol is a single drug?
nope
it’s actually a mixture of FOUR different drugs
RS, RR, SS, and SR-labetalol
and this is clinically relevant!
lets discuss why…
🧵 #1/3 #EMIMCC
nope
it’s actually a mixture of FOUR different drugs
RS, RR, SS, and SR-labetalol
and this is clinically relevant!
lets discuss why…
🧵 #1/3 #EMIMCC
Reposted by Steven Mathern
For many experts, Health. Secretary Kennedy’s promise to find autism’s causes in a few months is jarring — and unrealistic.
That’s because it appears to ignore decades of science linking about 200 genes that play a role.
apnews.com/article/auti...
That’s because it appears to ignore decades of science linking about 200 genes that play a role.
apnews.com/article/auti...
Experts call Kennedy's plan to find autism's cause unrealistic
Many autism experts say the Trump administration's plan to find autism's causes is unrealistic. Health Secretary Robert F.
apnews.com
May 11, 2025 at 12:41 AM
For many experts, Health. Secretary Kennedy’s promise to find autism’s causes in a few months is jarring — and unrealistic.
That’s because it appears to ignore decades of science linking about 200 genes that play a role.
apnews.com/article/auti...
That’s because it appears to ignore decades of science linking about 200 genes that play a role.
apnews.com/article/auti...
Reposted by Steven Mathern
tl;dr- egotistical edgelord intoxicatingly enamored with the (false) idea that he's far smarter than everyone else and therefore superior
Vinay Prasad, in his own words, outlines the philosophy he’ll bring to the FDA
Vinay Prasad, tapped to be a top official at the FDA, has never shied from speaking his mind.
www.statnews.com
May 6, 2025 at 10:00 PM
tl;dr- egotistical edgelord intoxicatingly enamored with the (false) idea that he's far smarter than everyone else and therefore superior
Reposted by Steven Mathern
Texas measles total tops 700 cases amid rises in other states www.cidrap.umn.edu/measles/texa...
Texas measles total tops 700 cases amid rises in other states
Also, health departments in Illinois, North Dakota, and Missouri reported more measles cases.
www.cidrap.umn.edu
May 6, 2025 at 10:56 PM
Texas measles total tops 700 cases amid rises in other states www.cidrap.umn.edu/measles/texa...
Reposted by Steven Mathern
20 years after it was approved, cardiologists are recognizing that ezetimibe is a great statin helper www.msn.com/en-us/health/other/cardiologists-say-statin-combination-therapy-can-reduce-cholesterol-related-deaths-by-49/ar-AA1CKN9r?ocid=msedgntp&pc=DCTS&cvid=77de09834e2542b09bdbdbf88b12fbac&ei=11
May 5, 2025 at 1:31 PM
20 years after it was approved, cardiologists are recognizing that ezetimibe is a great statin helper www.msn.com/en-us/health/other/cardiologists-say-statin-combination-therapy-can-reduce-cholesterol-related-deaths-by-49/ar-AA1CKN9r?ocid=msedgntp&pc=DCTS&cvid=77de09834e2542b09bdbdbf88b12fbac&ei=11
Reposted by Steven Mathern
Most vaccines don’t trigger mucosal IgA—a key airway defense
Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier
Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2
www.nature.com/articles/s41...
Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier
Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2
www.nature.com/articles/s41...
May 2, 2025 at 3:52 AM
Most vaccines don’t trigger mucosal IgA—a key airway defense
Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier
Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2
www.nature.com/articles/s41...
Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier
Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2
www.nature.com/articles/s41...
Reposted by Steven Mathern
🆕🔥 State of the art review article @cmicomms.bsky.social
Approach to Clostridioides difficile Diarrheal Infection ( CDI)
Excellent discussions about the management of CDI #IDsky #mustread
www.sciencedirect.com/science/arti...
Approach to Clostridioides difficile Diarrheal Infection ( CDI)
Excellent discussions about the management of CDI #IDsky #mustread
www.sciencedirect.com/science/arti...
May 1, 2025 at 2:58 AM
🆕🔥 State of the art review article @cmicomms.bsky.social
Approach to Clostridioides difficile Diarrheal Infection ( CDI)
Excellent discussions about the management of CDI #IDsky #mustread
www.sciencedirect.com/science/arti...
Approach to Clostridioides difficile Diarrheal Infection ( CDI)
Excellent discussions about the management of CDI #IDsky #mustread
www.sciencedirect.com/science/arti...
Reposted by Steven Mathern
🪪 𝐖𝐡𝐚𝐭 𝐢𝐬 teamcubancard.com?
Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you.
Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you.
May 1, 2025 at 8:44 PM
🪪 𝐖𝐡𝐚𝐭 𝐢𝐬 teamcubancard.com?
Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you.
Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you.
Reposted by Steven Mathern
Also given our HHS Secretary's comments about fetal cells in vaccines... here's a post I made about that:
open.substack.com/pub/deplatfo...
open.substack.com/pub/deplatfo...
![Fetal tissue use in vaccines [Imported Post from 03/09/2021]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:fpwat6yypl7sjbke3orwth7f/bafkreickbf2il6dkaat24t4p5tqfkyk6adjvq4xza36mtrbzgngobekn5i@jpeg)
May 1, 2025 at 9:04 PM
Also given our HHS Secretary's comments about fetal cells in vaccines... here's a post I made about that:
open.substack.com/pub/deplatfo...
open.substack.com/pub/deplatfo...
Reposted by Steven Mathern
Cool table from @bradspellberg.bsky.social of RCTs of vaccines, in case anyone honestly believes there have been no RCTs of today's routine childhood vaccines:
www.bradspellberg.com/vaccine-rcts
www.bradspellberg.com/vaccine-rcts
Vaccine RCTs | mysite
www.bradspellberg.com
May 1, 2025 at 10:47 PM
Cool table from @bradspellberg.bsky.social of RCTs of vaccines, in case anyone honestly believes there have been no RCTs of today's routine childhood vaccines:
www.bradspellberg.com/vaccine-rcts
www.bradspellberg.com/vaccine-rcts
Reposted by Steven Mathern
🆕🔥Case-control study @bradspellberg.bsky.social
Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability
Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC
jamanetwork.com/journals/jam...
Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability
Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC
jamanetwork.com/journals/jam...
May 1, 2025 at 8:50 PM
🆕🔥Case-control study @bradspellberg.bsky.social
Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability
Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC
jamanetwork.com/journals/jam...
Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability
Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC
jamanetwork.com/journals/jam...
Reposted by Steven Mathern
Just found Dr. Hotez here on Bluesky. 20,000 of you already knew he was here.
Great follow.
bsky.app/profile/pete...
Great follow.
bsky.app/profile/pete...
bsky.app
May 1, 2025 at 11:09 PM
Just found Dr. Hotez here on Bluesky. 20,000 of you already knew he was here.
Great follow.
bsky.app/profile/pete...
Great follow.
bsky.app/profile/pete...
Reposted by Steven Mathern
"most areas do not have experts in mycology" #IDSky @msgerc.bsky.social www.idse.net/Fungal-Infec...
Cosmetic Plastic Surgery Meningitis Mexico Mommy Makeover
Twenty-four patients who underwent cosmetic surgeries during 2023 in two clinics in Mexico developed <em>Fusarium solani </em>meningitis.
www.idse.net
April 30, 2025 at 6:40 PM
"most areas do not have experts in mycology" #IDSky @msgerc.bsky.social www.idse.net/Fungal-Infec...
Reposted by Steven Mathern
This #FINEHEART pooled analysis, published in #JACC, demonstrated that finerenone significantly reduced the risk of new-onset atrial fibrillation/atrial flutter across the CKM spectrum. www.jacc.org/doi/10.1016/... #AFib
Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis
www.jacc.org
April 30, 2025 at 6:19 PM
This #FINEHEART pooled analysis, published in #JACC, demonstrated that finerenone significantly reduced the risk of new-onset atrial fibrillation/atrial flutter across the CKM spectrum. www.jacc.org/doi/10.1016/... #AFib
'Lipid-related atherosclerotic risk is most accurately reflected by the total count of apoB-P and is largely unaffected by the major particle type (VLDL, LDL) or size. Elevated count of Lp(a) adds additional risk'
#apob #lpa apo(b) apolipoprotein b #ldl #cholesterol
academic.oup.com/eurheartj/ad...
#apob #lpa apo(b) apolipoprotein b #ldl #cholesterol
academic.oup.com/eurheartj/ad...
ApoB-containing lipoproteins: count, type, size, and risk of coronary artery disease
AbstractBackground and Aims. Apolipoprotein B concentration reflects the number of atherogenic lipoproteins and is recognized as a key lipid risk marker. W
academic.oup.com
April 30, 2025 at 12:08 PM
'Lipid-related atherosclerotic risk is most accurately reflected by the total count of apoB-P and is largely unaffected by the major particle type (VLDL, LDL) or size. Elevated count of Lp(a) adds additional risk'
#apob #lpa apo(b) apolipoprotein b #ldl #cholesterol
academic.oup.com/eurheartj/ad...
#apob #lpa apo(b) apolipoprotein b #ldl #cholesterol
academic.oup.com/eurheartj/ad...
'Defining and subphenotyping ARDS'
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Defining and subphenotyping ARDS: insights from an international Delphi expert panel
Although the definition of acute respiratory distress syndrome (ARDS) has undergone numerous revisions aimed at enhancing its diagnostic accuracy and …
www.sciencedirect.com
April 30, 2025 at 10:29 AM
'Defining and subphenotyping ARDS'
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
procedural sedation protocol, versed and ketamine
MidaKet for procedural sedation 😁
This is my go-to strategy for procedural sedation in sick, non-intubated patients.
Start with a mildly obtunding dose of midazolam, then add a moderate dose of ketamine.
Results in dissociative anesthesia & good resp/cardiovascular stability. 🧵 1/6 #EMIMCC
This is my go-to strategy for procedural sedation in sick, non-intubated patients.
Start with a mildly obtunding dose of midazolam, then add a moderate dose of ketamine.
Results in dissociative anesthesia & good resp/cardiovascular stability. 🧵 1/6 #EMIMCC
April 29, 2025 at 2:00 AM
procedural sedation protocol, versed and ketamine
Reposted by Steven Mathern
Updated vaccine RCT table looking amazing! Sorted for vaccine type, now more interactive in table, can click directly on the pubmed links in the table to go to the manuscripts.
bradspellberg.
www.bradspellberg.com/vaccine-rcts
bradspellberg.
www.bradspellberg.com/vaccine-rcts
Vaccine RCTs | mysite
www.bradspellberg.com
April 27, 2025 at 10:42 PM
Updated vaccine RCT table looking amazing! Sorted for vaccine type, now more interactive in table, can click directly on the pubmed links in the table to go to the manuscripts.
bradspellberg.
www.bradspellberg.com/vaccine-rcts
bradspellberg.
www.bradspellberg.com/vaccine-rcts
Reposted by Steven Mathern
Yes, actually in one of my responses on Twitter I wrote that I try to keep the tip of the CVC at least 5cm away from the tip of the dialysis catheter
April 27, 2025 at 3:10 PM
Yes, actually in one of my responses on Twitter I wrote that I try to keep the tip of the CVC at least 5cm away from the tip of the dialysis catheter
'ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC'
Similarly, am a proponent of CVC and Vascath placed in the same vein - pref RIJV.
Another tip is to ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC - specifically vasoactives.
Study below demonstrates this with an Abx model in piglets.
#EMIMCC
Another tip is to ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC - specifically vasoactives.
Study below demonstrates this with an Abx model in piglets.
#EMIMCC
April 27, 2025 at 10:54 AM
'ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC'
Reposted by Steven Mathern
🔴New publication in the CCI journal!🔴
Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support.
Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai!
📖 Full Text: onlinelibrary.wiley.com/share/author...
Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support.
Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai!
📖 Full Text: onlinelibrary.wiley.com/share/author...
onlinelibrary.wiley.com
April 25, 2025 at 2:23 AM
🔴New publication in the CCI journal!🔴
Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support.
Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai!
📖 Full Text: onlinelibrary.wiley.com/share/author...
Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support.
Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai!
📖 Full Text: onlinelibrary.wiley.com/share/author...