Ana Almeida
banner
ac-almeida.bsky.social
Ana Almeida
@ac-almeida.bsky.social
Postoctoring in🇨🇭@ivanagasic.bsky.social Lab
Cell biologist #Cytoskeleton & #Microscopy enthusiast 🔬🧫
Pinned
🔎New preprint!
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion and division. The availability of free tubul...
www.biorxiv.org
Reposted by Ana Almeida
And now… part two of our twin papers on how chromosomes find their place before division! Led by @krunovuk.bsky.social at @institutrb.bsky.social, out in @natcomms.nature.com!

doi.org/10.1038/s414...
doi.org/10.1038/s414...

Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
October 29, 2025 at 5:09 PM
Reposted by Ana Almeida
Huge congratulations to Wieczorek Lab PhD student Bin Cai and now-PI Jingwei Xu @xujwet.bsky.social on figuring out the surprisingly complex structure of the A-C linker crosslinking microtubule triplets in Tetrahymena basal body centrioles! www.science.org/doi/10.1126/...
Structure and assembly of the A-C linker connecting microtubule triplets in centrioles
Multiscale cryo-EM of centrioles reveals the structure and polymorphism of the A-C linker connecting microtubule triplets.
www.science.org
October 10, 2025 at 1:14 PM
Reposted by Ana Almeida
🚨 New preprint out!
“Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM” with Tithi Mandal and @rouxlab.bsky.social
We benchmark and describe step-by-step Flipper-TR FLIM measurements across different set-ups and and strategies.

www.biorxiv.org/content/10.1...
Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM
Flipper-TR is a membrane dye sensitive to lipid packing widely used to probe membrane tension in live cells via fluorescence lifetime imaging microscopy (FLIM). However, no consensus currently exists ...
www.biorxiv.org
October 5, 2025 at 4:04 PM
Can’t wait for the BioMatter Meeting in beautiful Arolla 🇨🇭⛰️
Amazing lineup of speakers + cutting-edge science on cytoskeleton dynamics from cells to tissues.
See you there!
📢 Last days to Join Arolla 2025!
📅 Aug 25–29, Grand Hotel, Arolla
🌍 For junior & senior scientists in cutting-edge bio research
🧬 Abstracts + reg close August 11
💸 Discounts for LS2 members!
👉 Info & reg: meetings.ls2.ch/arolla2025
August 8, 2025 at 5:22 AM
🔎New preprint!
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion and division. The availability of free tubul...
www.biorxiv.org
July 30, 2025 at 12:20 PM
EMBO Fellows Meeting 2025 just wrapped up!
4 intense days, 110+ talks, amazing postdocs, mentoring & networking!
Huge thanks to @embo.org & the organizers 👏
Feeling proud to be part of the next gen of scientists ready to push science forward.
Sharing a few highlights 📸
July 5, 2025 at 9:44 AM
Reposted by Ana Almeida
📢We are live everyone ! ! !

We are happy to announce that our official WEBSITE is now online - and early bird registration is OPEN 🎉

👀👇Come check it out🚀🌟

spaom2025.org
🚩Braga, Portugal
📅November 5-7, 2025

#microscopy #science #bioimaging #advancedmicroscopy #spatialbiology #photonics
May 14, 2025 at 11:56 AM
Last call for abstracts! 👇
#postdocday
🚨 Last week to submit abstracts for talks & posters!
Show your research, win prizes & enjoy surprises 🎉
Register here: ‘’ shorturl.at/eOmJt ‘’
May 13, 2025 at 4:47 PM
Reposted by Ana Almeida
Two cells, one twist 🧬🔁
Myosin asymmetry breaks mirror symmetry & sparks spontaneous 3D rotations in doublets.
Adherens junctions🩶, focal adhesions🟢 & actomyosin🔴 Biology meets active matter physics.
#CellPolarity #Fluorescencefriday #ActiveMatter #Microscopy
May 2, 2025 at 2:02 PM
Reposted by Ana Almeida
Did you know the cell wall of mycobacteria isn’t just for protection? 🧱👀 Here, Mycobacterium marinum sheds its outer capsule right after being eaten by Dicty! A sneaky move that affects even nearby cells… #FluorescenceFriday #Mycobacteria #CellBiology #Infection #3Rmodels #Phagocytosis
May 9, 2025 at 7:21 AM
Reposted by Ana Almeida
New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work! www.biorxiv.org/content/10.1...
April 23, 2025 at 2:04 PM
Reposted by Ana Almeida
🔬 A new probe developed by Janelia researchers & collaborators that enables visualization of extracellular matrix structure in live tissues could also be useful in studying diseases linked to changes in the extracellular matrix and in diagnostic imaging ➡️ www.janelia.org/news/looking...
April 29, 2025 at 3:55 PM
Reposted by Ana Almeida
This stunning image was made by @ac-almeida.bsky.social , our brilliant President and microtubule enthusiast! She's passionate about how the cytoskeleton organizes itself in 3D—seriously cool stuff! 🧠🧵✨#Microscopy #WomenInSTEM #Cytoskeleton
@mocel.bsky.social
April 25, 2025 at 1:48 PM
Reposted by Ana Almeida
Behold: a human cancer spheroid! This 3D cell blob models solid tumors. DAPI (blue) marks nuclei, PI lights up the dead. Z-plane colors unveil a rainbow necrotic core wrapped in a moody, monochrome outer layer. #fluorescencefriday #microscopy #postdoc
April 25, 2025 at 1:48 PM