Willie Neiswanger
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willieneis.bsky.social
Willie Neiswanger
@willieneis.bsky.social
Assistant Professor in CS + AI at USC. Previously at Stanford, CMU. Machine Learning, Decision Making, AI-for-Science, Generative AI, ML Systems, LLMs.

https://willieneis.github.io
Pinned
I'm making a list of AI for Science researchers on bluesky — let me know if I missed you / if you'd like to join!

go.bsky.app/AcP9Lix
Reposted by Willie Neiswanger
Announcing 🔭Hubble, a suite of open-source LLMs to advance the study of memorization!

Pretrained 1B/8B param models, with controlled insertion of texts designed to emulate key memorization risks: copyright (e.g., book passages), privacy (e.g., synthetic biographies), and test set contamination
October 24, 2025 at 6:21 PM
Reposted by Willie Neiswanger
😃 Want strong LLM reasoning without breaking the bank? We explored just how cost-effectively RL can enhance reasoning using LoRA!

[1/9] Introducing Tina: A family of tiny reasoning models with strong performance at low cost, providing an accessible testbed for RL reasoning. 🧵
April 23, 2025 at 5:10 PM
Reposted by Willie Neiswanger
🔍 Diving deep into LLM reasoning?

From OpenAI's o-series to DeepSeek R1, from post-training to test-time compute — we break it down into structured spreadsheets. 🧵
February 19, 2025 at 6:01 PM
Excited to release METAGENE-1, a 7B parameter metagenomic foundation model, built to aid in pathogen detection & pandemic monitoring. Pretrained on 1.5 trillion base pairs of DNA/RNA sequenced from wastewater.

A collab w/ USC, PrimeIntellect, & the Nucleic Acid Observatory.

metagene.ai
Metagenomic Foundation Model
Metagenomic Foundation Model for Pandemic Monitoring
metagene.ai
January 7, 2025 at 8:58 PM
Reposted by Willie Neiswanger
Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding.

(E.g., where does that “log” come from? Are there other possible formulas?)

Yet there's an intuitive & almost inevitable way to arrive at this expression.
December 9, 2024 at 10:44 PM
Reposted by Willie Neiswanger
hi everyone!! let's try this optimal transport again 🙃
December 5, 2024 at 12:58 PM
Reposted by Willie Neiswanger
Delighted to publish my new molecular animation:

DNA Break Repair by Homologous Recombination

youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tv
YouTube video by WEHImovies
youtu.be
December 4, 2024 at 12:07 AM
Reposted by Willie Neiswanger
Anne Gagneux, Ségolène Martin, @quentinbertrand.bsky.social Remi Emonet and I wrote a tutorial blog post on flow matching: dl.heeere.com/conditional-... with lots of illustrations and intuition!

We got this idea after their cool work on improving Plug and Play with FM: arxiv.org/abs/2410.02423
November 27, 2024 at 9:00 AM
Reposted by Willie Neiswanger
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
November 17, 2024 at 4:20 PM
Reposted by Willie Neiswanger
We've made a starter pack for researchers/organizations working on open-source LLMS.

Please let us know if we missed you or if you'd like to be added!

go.bsky.app/FELkyDr
Open-source LLMs
Join the conversation
go.bsky.app
November 20, 2024 at 1:33 AM
Reposted by Willie Neiswanger
Since creating an API that can deliver crow facts via REST, I've delivered 3,250 crow facts as JSON. Get yours today:

curl facts.drugcrow.ai

explanation: diffuse.one/p/d1-004
November 16, 2024 at 3:30 AM
Reposted by Willie Neiswanger
Talk: Speculations on Test-Time Scaling

A tutorial on the technical aspects behind OpenAI's o1 and open research questions in this space.

youtu.be/6PEJ96k1kiw
Slides+bibliography: github.com/srush/awesom...
Speculations on Test-Time Scaling (o1)
YouTube video by Sasha Rush 🤗
youtu.be
November 12, 2024 at 12:36 PM
Reposted by Willie Neiswanger
Trembling with excitement in announcing the first ever International Conference on Probabilistic Numerics! Probabilistic Numerics is about machine learning FOR numerical computation, like optimisation. 1st - 3rd September 2025, EURECOM, France, submissions due 5th March 2025. probnum25.github.io
ProbNum25
Coming
probnum25.github.io
November 12, 2024 at 10:44 AM
Reposted by Willie Neiswanger
Visualize infinite series! Here's a page I made a few years ago, letting you play with convergence and divergence.
www.bewitched.com/demo/taylor/...
Visual Taylor Series
Visualizations of Taylor Series, based on diagrams from Amie Wilkinson
www.bewitched.com
November 12, 2024 at 2:46 AM
Reposted by Willie Neiswanger
trying to make a diagram of the cast of characters in the terminal and so far it's very chaotic
November 11, 2024 at 9:16 PM
Reposted by Willie Neiswanger
There are a lot of discussion on if "scaling is done," with stories from the Information saying that the latest GPT models aren't showing what OpenAI wanted while Sam Altman still parades around saying AGI is near. I wanted to explain why both of these can be true.
November 11, 2024 at 8:52 PM
I'm making a list of AI for Science researchers on bluesky — let me know if I missed you / if you'd like to join!

go.bsky.app/AcP9Lix
November 10, 2024 at 12:11 AM
Useful!
New here? Interested in AI/ML? Check out these great starter packs!

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You can also search all starter packs here: blueskydirectory.com/starter-pack...
November 9, 2024 at 10:19 PM