Will Glynn
@willglynn.bsky.social
I work in a lab performing extractions, PCRs and other molecular biology techniques | Amateur astronomer | Dabbler in languages | Living with ARVC | he/him/his
My mini-haul from the second-hand bookshop at the Weald and Downland Living Museum, Sussex. Lately I’ve been listening to a lot of Björk and trying to improve my Gaeilge, so I thought this was an apt selection 📚💙
October 28, 2025 at 7:07 PM
My mini-haul from the second-hand bookshop at the Weald and Downland Living Museum, Sussex. Lately I’ve been listening to a lot of Björk and trying to improve my Gaeilge, so I thought this was an apt selection 📚💙
Reposted by Will Glynn
Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.
June 19, 2025 at 11:21 AM
Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.
Reposted by Will Glynn
Fresh JWST view of Uranus taken Oct 6 2025 with NIRCam.
Full size & more info: flic.kr/p/2rByidu 🔭🧪
Credit: NASA/ESA/CSA/STScI/Andrea Luck CC BY
Proposal PI: Varun Bajaj
Proposal ID: 8975
Filters: F150W2-F162M, F410M
Full size & more info: flic.kr/p/2rByidu 🔭🧪
Credit: NASA/ESA/CSA/STScI/Andrea Luck CC BY
Proposal PI: Varun Bajaj
Proposal ID: 8975
Filters: F150W2-F162M, F410M
October 26, 2025 at 2:04 PM
Fresh JWST view of Uranus taken Oct 6 2025 with NIRCam.
Full size & more info: flic.kr/p/2rByidu 🔭🧪
Credit: NASA/ESA/CSA/STScI/Andrea Luck CC BY
Proposal PI: Varun Bajaj
Proposal ID: 8975
Filters: F150W2-F162M, F410M
Full size & more info: flic.kr/p/2rByidu 🔭🧪
Credit: NASA/ESA/CSA/STScI/Andrea Luck CC BY
Proposal PI: Varun Bajaj
Proposal ID: 8975
Filters: F150W2-F162M, F410M
My favourite space artist, do give him a follow #sciart 🔭
Each year near the start of Mars' southern winter warm air rises over Arsia Mons volcano forming ice and dust clouds. Sometimes this dust coalesces into a spiraling cloud that can be over 15 km high. This digital painting depicts one such dust spirals.#Sciart #space #astronomy #SolarSystem #Mars
October 23, 2025 at 6:28 PM
My favourite space artist, do give him a follow #sciart 🔭
Reposted by Will Glynn
Chromosome replication and cell division cycles are not synchronized in Staphylococcus aureus, with cells exhibiting two segregated origins of replication at the start of the cell cycle
#bacteria #microbiology
#bacteria #microbiology
Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus - Nature Communications
Our understanding of chromosome organization and dynamics in spherical bacteria, such as Staphylococcus aureus, remains limited. Here, the authors show that chromosome replication and cell division cycles are not synchronized in S. aureus, with cells exhibiting two segregated origins of replication at the start of the cell cycle.
bit.ly
October 21, 2025 at 2:51 PM
Chromosome replication and cell division cycles are not synchronized in Staphylococcus aureus, with cells exhibiting two segregated origins of replication at the start of the cell cycle
#bacteria #microbiology
#bacteria #microbiology
The clouds parted just long enough tonight for me to photograph an ice giant — #Uranus. The planet is currently situated between the Pleiades and Lambda Tauri (part of the constellation Taurus) 🔭🧪
October 19, 2025 at 10:08 PM
The clouds parted just long enough tonight for me to photograph an ice giant — #Uranus. The planet is currently situated between the Pleiades and Lambda Tauri (part of the constellation Taurus) 🔭🧪
From Antarctic eelpouts to African cichlids, the percomorph (literally “perch-like”) fishes have been a remarkable system for studying how genomic changes underpin evolution by natural selection 🐠🐟🧪
Excited to share this work, out today in MBE! In polar fishes, we found that antifreeze protein genes expanded in copy number at low temperatures and contracted in the deep sea, highlighting a role of depth and pressure in AFP evolution.
🔗 academic.oup.com/mbe/article/...
🔗 academic.oup.com/mbe/article/...
October 18, 2025 at 4:04 PM
From Antarctic eelpouts to African cichlids, the percomorph (literally “perch-like”) fishes have been a remarkable system for studying how genomic changes underpin evolution by natural selection 🐠🐟🧪
Thrilled to announce that I’ve started studying for a Postgraduate Diploma in Biomedical Science with the University of Greenwich. My first module is Advanced Human Genetics 🧬🧪 🥼
October 18, 2025 at 3:54 PM
Thrilled to announce that I’ve started studying for a Postgraduate Diploma in Biomedical Science with the University of Greenwich. My first module is Advanced Human Genetics 🧬🧪 🥼
Sunset over the South Downs 🌅🔭
October 9, 2025 at 10:38 PM
Sunset over the South Downs 🌅🔭
Reposted by Will Glynn
Lundi, on fête les 30 ans de l'annonce de la détection de la 1ère exoplanète à avoir été découverte en orbite autour d'une étoile de type solaire, par Didier Queloz et Michel Mayor, prix Nobel de physique 2019. C'était le 6 octobre 1995 à Florence, et c'était 51 Pegasi b, la 1ère "Jupiter chaude" 🧵👇
October 3, 2025 at 1:29 PM
Lundi, on fête les 30 ans de l'annonce de la détection de la 1ère exoplanète à avoir été découverte en orbite autour d'une étoile de type solaire, par Didier Queloz et Michel Mayor, prix Nobel de physique 2019. C'était le 6 octobre 1995 à Florence, et c'était 51 Pegasi b, la 1ère "Jupiter chaude" 🧵👇
Something has taken a bite out of this wood fungus, which looks like a relative of chicken-of-the-woods #FungiFriends #MushroomMonday
September 22, 2025 at 7:01 PM
Something has taken a bite out of this wood fungus, which looks like a relative of chicken-of-the-woods #FungiFriends #MushroomMonday
The best characterised oncogenic gene fusion is that of BCR and ABL1, made by translocation from chromosome 9 to 22 (aka a Philadelphia chromosome). Targeting BCR::ABL1 has already revolutionised treatment of chronic myelogenous leukaemia. How many other cancers could be managed in a similar way?
This review from @gumedcenter.bsky.social provides an overview of oncogenic #GeneFusions and its prevalence in #cancer, with insights into the detection methods, therapeutic strategies, and clinical studies on fusion-positive cancers. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
September 22, 2025 at 6:02 PM
The best characterised oncogenic gene fusion is that of BCR and ABL1, made by translocation from chromosome 9 to 22 (aka a Philadelphia chromosome). Targeting BCR::ABL1 has already revolutionised treatment of chronic myelogenous leukaemia. How many other cancers could be managed in a similar way?
Reposted by Will Glynn
This isn't all I'd hoped it would be, due to less than ideal sky conditions and an equipment issue. But this is the transit of Titan and its shadow on Saturn. Ideally the photograph would resolve the moon from its shadow, but I'm still hoping for points for effort. #Astronomy #Astrophotography
September 20, 2025 at 5:41 PM
This isn't all I'd hoped it would be, due to less than ideal sky conditions and an equipment issue. But this is the transit of Titan and its shadow on Saturn. Ideally the photograph would resolve the moon from its shadow, but I'm still hoping for points for effort. #Astronomy #Astrophotography
Reposted by Will Glynn
Es hat etwas gedauert, aber hier nun endlich die entscheidenden Momente der gestrigen Venusbedeckung durch die schmale Mondsichel 😊🔭
September 20, 2025 at 6:39 PM
Es hat etwas gedauert, aber hier nun endlich die entscheidenden Momente der gestrigen Venusbedeckung durch die schmale Mondsichel 😊🔭
Wie ein Stück Meissener Porzellan #FungiFriends 🍄🍄🟫
September 20, 2025 at 7:17 PM
Wie ein Stück Meissener Porzellan #FungiFriends 🍄🍄🟫
Reposted by Will Glynn
A genocide is unfolding, and Donald Trump is the one man in the world with the power to make it stop.
If the Prime Minister is going to wine and dine Donald Trump, he must also him to finally take action to end the assault on Gaza City, stop the aid blockade and secure the release of hostages.
If the Prime Minister is going to wine and dine Donald Trump, he must also him to finally take action to end the assault on Gaza City, stop the aid blockade and secure the release of hostages.
September 19, 2025 at 8:08 AM
A genocide is unfolding, and Donald Trump is the one man in the world with the power to make it stop.
If the Prime Minister is going to wine and dine Donald Trump, he must also him to finally take action to end the assault on Gaza City, stop the aid blockade and secure the release of hostages.
If the Prime Minister is going to wine and dine Donald Trump, he must also him to finally take action to end the assault on Gaza City, stop the aid blockade and secure the release of hostages.
Happy first birthday to my ICD! I’m eternally grateful for the new lease of life it’s given me #cardiology #ARVC #cardiomyopathy
September 18, 2025 at 10:09 AM
Happy first birthday to my ICD! I’m eternally grateful for the new lease of life it’s given me #cardiology #ARVC #cardiomyopathy
Reposted by Will Glynn
New Online! Mechanisms of human germ cell development
Mechanisms of human germ cell development
Nature Reviews Molecular Cell Biology, Published online: 16 September 2025; doi:10.1038/s41580-025-00893-6Human germ cells are specified during early development and eventually differentiate into sperm and oocytes. Recent studies have revealed key signalling pathways and epigenetic mechanisms of their development, enabling in vitro reconstitution and potential treatments for germ cell-related diseases.
bit.ly
September 16, 2025 at 11:41 AM
New Online! Mechanisms of human germ cell development
The UK must also end its complicity #StopTheGenocide
Today, the UN officially designated Israel’s assault on Gaza as a genocide.
As a party to the Genocide Convention, the U.S. has a legal obligation to obey our own laws, stop weapons sales to Israel, and demand a permanent ceasefire.
End the genocide. Ceasefire now.
As a party to the Genocide Convention, the U.S. has a legal obligation to obey our own laws, stop weapons sales to Israel, and demand a permanent ceasefire.
End the genocide. Ceasefire now.
September 16, 2025 at 4:55 PM
The UK must also end its complicity #StopTheGenocide
Reposted by Will Glynn
How many chromosomes can an animal have?
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
Constraints on chromosome evolution revealed by the 229 chromosome pairs of the Atlas blue butterfly
The genome of the Atlas blue butterfly contains ten times more chromosomes than most
butterflies, and more than any other known diploid animal. Wright et al. show that
this extraordinary karyotype is ...
tinyurl.com
September 11, 2025 at 3:22 PM
How many chromosomes can an animal have?
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
Reposted by Will Glynn
If you see headlines claiming NASA's found life on Mars - these are new studies of features in rocks which, if they were on Earth, look like the kind of thing caused by microorganisms. But they could very well - are most probably in fact - be caused by chemistry, not biology.
September 10, 2025 at 10:16 PM
If you see headlines claiming NASA's found life on Mars - these are new studies of features in rocks which, if they were on Earth, look like the kind of thing caused by microorganisms. But they could very well - are most probably in fact - be caused by chemistry, not biology.
Closing blackberries of the season did not disappoint 😋🌱
September 11, 2025 at 10:20 PM
Closing blackberries of the season did not disappoint 😋🌱