Sandeep Thekkepat
@tsandeep.bsky.social
Endocrinology | Clinical Informatics |
Can't wait to read @jarrodkimber.bsky.social take on the 🐐 Virat Kohli!
November 26, 2025 at 1:18 PM
Can't wait to read @jarrodkimber.bsky.social take on the 🐐 Virat Kohli!
Reposted by Sandeep Thekkepat
Nailed it. The modern age of digital colonizers is in full swing.
If I’m understanding this correctly, X is owned by a white nationalist who pays poor people of color in developing countries to pretend to be working class white Americans to scare other white Americans into being afraid poor people of color from developing countries are going to ruin America?
November 23, 2025 at 8:06 PM
Nailed it. The modern age of digital colonizers is in full swing.
Art of Batting Smriti Mandhana edition! 6 pitches! @jarrodkimber.bsky.social
www.cricbuzz.com/cricket-news...
www.cricbuzz.com/cricket-news...
November 23, 2025 at 10:38 PM
Art of Batting Smriti Mandhana edition! 6 pitches! @jarrodkimber.bsky.social
www.cricbuzz.com/cricket-news...
www.cricbuzz.com/cricket-news...
Reposted by Sandeep Thekkepat
🧰 The ISN Early CKD Detection Toolbox helps you design and sustain screening programs.
This toolbox is part of a broader resource developed by ISN and KDIGO, linking key steps to practical, evidence-based resources—adaptable to all settings.
➡️ http://lite.spr.ly/6...
This toolbox is part of a broader resource developed by ISN and KDIGO, linking key steps to practical, evidence-based resources—adaptable to all settings.
➡️ http://lite.spr.ly/6...
November 13, 2025 at 6:00 AM
🧰 The ISN Early CKD Detection Toolbox helps you design and sustain screening programs.
This toolbox is part of a broader resource developed by ISN and KDIGO, linking key steps to practical, evidence-based resources—adaptable to all settings.
➡️ http://lite.spr.ly/6...
This toolbox is part of a broader resource developed by ISN and KDIGO, linking key steps to practical, evidence-based resources—adaptable to all settings.
➡️ http://lite.spr.ly/6...
Reposted by Sandeep Thekkepat
📢 The 2nd EASD Diabetes Technology School is now open for applications:
📅 24 - 26 April 2026 |📍Vienna, Austria
A 3 day course for #healthcare professionals to enhance their expertise in #diabetes #technology.
Apply by 5 January 2026 👉 www.easd.org/education/me...
#MedicalTraining #innovation
📅 24 - 26 April 2026 |📍Vienna, Austria
A 3 day course for #healthcare professionals to enhance their expertise in #diabetes #technology.
Apply by 5 January 2026 👉 www.easd.org/education/me...
#MedicalTraining #innovation
November 12, 2025 at 10:42 AM
📢 The 2nd EASD Diabetes Technology School is now open for applications:
📅 24 - 26 April 2026 |📍Vienna, Austria
A 3 day course for #healthcare professionals to enhance their expertise in #diabetes #technology.
Apply by 5 January 2026 👉 www.easd.org/education/me...
#MedicalTraining #innovation
📅 24 - 26 April 2026 |📍Vienna, Austria
A 3 day course for #healthcare professionals to enhance their expertise in #diabetes #technology.
Apply by 5 January 2026 👉 www.easd.org/education/me...
#MedicalTraining #innovation
As dust settles on the historic, Indian Women cricket team’s World Cup triumph in Navi Mumbai, I loved these two articles/YT
1. www.espncricinfo.com/story/how-in... by Sid Monga
2. youtu.be/q4NVxnviSIk?...
by @jarrodkimber.bsky.social
1. www.espncricinfo.com/story/how-in... by Sid Monga
2. youtu.be/q4NVxnviSIk?...
by @jarrodkimber.bsky.social
Sisters vs uncles: how India's women have struck a blow for their kind all over the country
By winning the World Cup, they have lived up to long-held expectations, taken their place in the mainstream, and made a statement for their sport
www.espncricinfo.com
November 11, 2025 at 7:15 AM
As dust settles on the historic, Indian Women cricket team’s World Cup triumph in Navi Mumbai, I loved these two articles/YT
1. www.espncricinfo.com/story/how-in... by Sid Monga
2. youtu.be/q4NVxnviSIk?...
by @jarrodkimber.bsky.social
1. www.espncricinfo.com/story/how-in... by Sid Monga
2. youtu.be/q4NVxnviSIk?...
by @jarrodkimber.bsky.social
Reposted by Sandeep Thekkepat
Our new paper in @diabetologiajnl.bsky.social shows persistent C-peptide secretion is associated with favourable CGM metrics - relevant threshold appears to be ~50pM @shareenforbeslab.bsky.social
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Persistent C-peptide secretion is associated with favourable CGM metrics in adults with type 1 diabetes - Diabetologia
Aims/hypothesis Residual endogenous insulin secretion, reflected by measurable C-peptide, has been linked to improved glycaemic management in type 1 diabetes. We aimed to assess the relationship betwe...
link.springer.com
October 30, 2025 at 4:43 PM
Our new paper in @diabetologiajnl.bsky.social shows persistent C-peptide secretion is associated with favourable CGM metrics - relevant threshold appears to be ~50pM @shareenforbeslab.bsky.social
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Not good for the staff who will lose their jobs. The management have been negligent with scant regard for patients and professionals. Just focussed on share price 🤷🏼♂️ Supply chain issues, arbitrary withdrawal of insulins etc. Patent renewal shouldn’t happen and generics should come on board soon.
Wegovy-maker Novo Nordisk to cut 9,000 jobs in restructuring reut.rs/3V5U0rD
Wegovy-maker Novo Nordisk to cut 9,000 jobs in restructuring
Wegovy-maker Novo Nordisk will cut 9,000 jobs in a restructuring, aiming to save 8 billion Danish crowns ($1.26 billion) annually, the company said on Wednesday, as it battles rising pressure from main U.S. rival Eli Lilly .
reut.rs
September 10, 2025 at 11:26 AM
Not good for the staff who will lose their jobs. The management have been negligent with scant regard for patients and professionals. Just focussed on share price 🤷🏼♂️ Supply chain issues, arbitrary withdrawal of insulins etc. Patent renewal shouldn’t happen and generics should come on board soon.
Reposted by Sandeep Thekkepat
The latest 2025 #Hypertension Guidelines are out 📣
#Nephpearls #NephSky
📌 On checking Office and Home BP
👉🏼 pubmed.ncbi.nlm.nih.gov/40811516/
#Nephpearls #NephSky
📌 On checking Office and Home BP
👉🏼 pubmed.ncbi.nlm.nih.gov/40811516/
August 15, 2025 at 11:45 AM
The latest 2025 #Hypertension Guidelines are out 📣
#Nephpearls #NephSky
📌 On checking Office and Home BP
👉🏼 pubmed.ncbi.nlm.nih.gov/40811516/
#Nephpearls #NephSky
📌 On checking Office and Home BP
👉🏼 pubmed.ncbi.nlm.nih.gov/40811516/
Reposted by Sandeep Thekkepat
The treatment of TB goes way beyond access and affordability of medications.
Book Club for #NephJC
Evething is Tuberculosis @johngreensbluesky.bsky.social
Discuss 8/19/25 9pm EST
Book Club for #NephJC
Evething is Tuberculosis @johngreensbluesky.bsky.social
Discuss 8/19/25 9pm EST
Sometimes, blame for failed TB treatments is placed on patients not taking their meds. Dr. Farmer tried something new; he gave everyone free medicine, but also gave some food, money for childcare and transportation, and home visits from his staff. Everyone in the second group was cured. #TBReaders
August 1, 2025 at 1:26 PM
The treatment of TB goes way beyond access and affordability of medications.
Book Club for #NephJC
Evething is Tuberculosis @johngreensbluesky.bsky.social
Discuss 8/19/25 9pm EST
Book Club for #NephJC
Evething is Tuberculosis @johngreensbluesky.bsky.social
Discuss 8/19/25 9pm EST
Reposted by Sandeep Thekkepat
Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action
Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.
www.science.org
July 31, 2025 at 6:52 PM
Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...
One way to defeat AI in the future 😉 Paging John Connor!
Handwritten labels and watermarks on histopathological images can unintentionally act as prompt injections, misleading vision–language models and resulting in inaccurate outputs that highlight a critical vulnerability in medical #AI systems. Learn more: nejm.ai/4mrSoEW
#MedSky #DigitalHealth
#MedSky #DigitalHealth
June 19, 2025 at 8:12 PM
One way to defeat AI in the future 😉 Paging John Connor!
Reposted by Sandeep Thekkepat
As usual I can’t say enough good things about @ukkidney.org guidelines - their flozin one is fantastic, and I’m pleased to say their clear summary is supportive of this practice👇
November 22, 2024 at 4:46 PM
As usual I can’t say enough good things about @ukkidney.org guidelines - their flozin one is fantastic, and I’m pleased to say their clear summary is supportive of this practice👇
Reposted by Sandeep Thekkepat
Shoutout to reading.
June 9, 2025 at 4:57 PM
Shoutout to reading.
Reposted by Sandeep Thekkepat
The @americanheart.bsky.social just published their alcohol recommendations today which line up with the report by National Academies. Moderate EtOH intake, up to 7 drinks per week (1/day), is without risk (and may be beneficial for cardiovascular outcomes)
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
June 9, 2025 at 5:24 PM
The @americanheart.bsky.social just published their alcohol recommendations today which line up with the report by National Academies. Moderate EtOH intake, up to 7 drinks per week (1/day), is without risk (and may be beneficial for cardiovascular outcomes)
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
Reposted by Sandeep Thekkepat
it’s time to replace all doctors with ai
June 5, 2025 at 1:46 AM
it’s time to replace all doctors with ai
The news keeps on coming! www.theguardian.com/us-news/2025...
RFK Jr threatens ban on federal scientists publishing in top journals
US health secretary calls leading medical journals such as Lancet ‘corrupt’ and pushes to create state-run alternatives
www.theguardian.com
May 28, 2025 at 4:03 PM
The news keeps on coming! www.theguardian.com/us-news/2025...
Reposted by Sandeep Thekkepat
This is perhaps the best essay on this sad and fateful mess www.politico.com/news/magazin...
Opinion | All the President's Enablers
Three books on Joe Biden’s presidency jointly paint a devastating portrait of an ailing, geriatric leader surrounded by mendacious aides and grasping family members.
www.politico.com
May 21, 2025 at 2:52 AM
This is perhaps the best essay on this sad and fateful mess www.politico.com/news/magazin...
Reposted by Sandeep Thekkepat
In September, 2024, physicians working with AI did better at the Healthbench doctor benchmark than either AI or physicians alone.
With the release of o3 and GPT-4.1, AI answers are no longer improved on by physicians
Error rates appear to be dropping for newer AI models. openai.com/index/health...
With the release of o3 and GPT-4.1, AI answers are no longer improved on by physicians
Error rates appear to be dropping for newer AI models. openai.com/index/health...
May 13, 2025 at 4:23 AM
In September, 2024, physicians working with AI did better at the Healthbench doctor benchmark than either AI or physicians alone.
With the release of o3 and GPT-4.1, AI answers are no longer improved on by physicians
Error rates appear to be dropping for newer AI models. openai.com/index/health...
With the release of o3 and GPT-4.1, AI answers are no longer improved on by physicians
Error rates appear to be dropping for newer AI models. openai.com/index/health...
Reposted by Sandeep Thekkepat
Also read the linked comment by Kay Weng Choy & Cherie Chiang:
Diagnosing arginine vasopressin deficiency and primary polydipsia www.thelancet.com/journals/lan...
#diabetes #insipidus
#MedSky #EndoSky #NeuroSky
#FREE to read with registration (also FREE)
Diagnosing arginine vasopressin deficiency and primary polydipsia www.thelancet.com/journals/lan...
#diabetes #insipidus
#MedSky #EndoSky #NeuroSky
#FREE to read with registration (also FREE)
Diagnosing arginine vasopressin deficiency and primary polydipsia
A crucial step in evaluating hypotonic polyuria and polydipsia is distinguishing between
the rarer, potentially life-threatening arginine vasopressin deficiency and the more
common primary polydipsia,...
www.thelancet.com
April 25, 2025 at 10:41 PM
Also read the linked comment by Kay Weng Choy & Cherie Chiang:
Diagnosing arginine vasopressin deficiency and primary polydipsia www.thelancet.com/journals/lan...
#diabetes #insipidus
#MedSky #EndoSky #NeuroSky
#FREE to read with registration (also FREE)
Diagnosing arginine vasopressin deficiency and primary polydipsia www.thelancet.com/journals/lan...
#diabetes #insipidus
#MedSky #EndoSky #NeuroSky
#FREE to read with registration (also FREE)
Reposted by Sandeep Thekkepat
A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia w/ basal laboratory parameters & a novel diagnostic score: results from two international multicentre prospective diagnostic studies www.thelancet.com/journals/lan... #EndoSky
April 25, 2025 at 10:41 PM
A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia w/ basal laboratory parameters & a novel diagnostic score: results from two international multicentre prospective diagnostic studies www.thelancet.com/journals/lan... #EndoSky
Reposted by Sandeep Thekkepat
A high polygenic risk score (PRS) for screening prostate cancer was superior to a PSA test or MRI for detecting clinically significant disease (Gleason ≥7). A big step forward for supporting utility of PRS @nejm.org
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Assessment of a Polygenic Risk Score in Screening for Prostate Cancer | NEJM
The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific
antigen (PSA) has a high rate for false positive results. Genomewide association studies
have identified...
www.nejm.org
April 9, 2025 at 9:25 PM
A high polygenic risk score (PRS) for screening prostate cancer was superior to a PSA test or MRI for detecting clinically significant disease (Gleason ≥7). A big step forward for supporting utility of PRS @nejm.org
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Reposted by Sandeep Thekkepat
An AI tool to diagnose chronic obstructive pulmonary disease (COPD) is due to be rolled out to the NHS, offering patients an alternative to traditional spirometry.
Full story 👉 ow.ly/xf7550VtGRS
Full story 👉 ow.ly/xf7550VtGRS
April 3, 2025 at 8:16 AM
An AI tool to diagnose chronic obstructive pulmonary disease (COPD) is due to be rolled out to the NHS, offering patients an alternative to traditional spirometry.
Full story 👉 ow.ly/xf7550VtGRS
Full story 👉 ow.ly/xf7550VtGRS
Reposted by Sandeep Thekkepat
a low renin, especially a low renin while on a medication known to raise renin (ACEi/ARB/MRA/ENaCi) is likely some degree of primary aldosteronism. Either way, a phenotype that will respond to MRA therapy very well
April 3, 2025 at 1:07 AM
a low renin, especially a low renin while on a medication known to raise renin (ACEi/ARB/MRA/ENaCi) is likely some degree of primary aldosteronism. Either way, a phenotype that will respond to MRA therapy very well
We need that Sreesanth episode! @jarrodkimber.bsky.social
March 31, 2025 at 10:58 PM
We need that Sreesanth episode! @jarrodkimber.bsky.social