Teresa Mastracci
@teresamastracci.bsky.social
Associate Professor, Department of Biology @ Indiana University Indianapolis @iuibiology.bsky.social
My lab focuses on diabetes & rare disease research. Science enthusiast. Proudly 🇨🇦
My lab focuses on diabetes & rare disease research. Science enthusiast. Proudly 🇨🇦
Pinned
Analysis of translational regulation using polysome profiling and puromycin incorporation
Translation is the process of decoding an mRNA transcript to permit the synthesis of a protein. This process occurs in three steps: initiation, elonga…
www.sciencedirect.com
New publication from the #Mastracci lab,which outlines 2 techniques that measure changes in mRNA #translation: polysome profiling and puromycin incorporation. We have detailed step-by-step protocols, including all the needed reagents to execute these techniques!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Congratulations to Dr. Al Powers — recognized with the Lacy Medal Award at the Midwest Islet Club meeting. So incredibly well deserved!! My scientific career was greatly impacted by you — so very thankful for your time and mentorship, Al! #MIC2025
May 7, 2025 at 9:29 PM
Congratulations to Dr. Al Powers — recognized with the Lacy Medal Award at the Midwest Islet Club meeting. So incredibly well deserved!! My scientific career was greatly impacted by you — so very thankful for your time and mentorship, Al! #MIC2025
Reposted by Teresa Mastracci
Fantastic talks just now from experts @teresamastracci.bsky.social and @rlhull-meichle.bsky.social on crosstalk between the #islet and the surrounding #acinar and vascular tissue... are there novel pancreatic targets outside the islet to treat #T1D and #T2D? 🇨🇦 Nat'l Grad Course @uoft.bsky.social
April 23, 2025 at 7:15 PM
Fantastic talks just now from experts @teresamastracci.bsky.social and @rlhull-meichle.bsky.social on crosstalk between the #islet and the surrounding #acinar and vascular tissue... are there novel pancreatic targets outside the islet to treat #T1D and #T2D? 🇨🇦 Nat'l Grad Course @uoft.bsky.social
Reposted by Teresa Mastracci
Some thoughts on the new dynamic uncertain status and need for US-Canada Science diplomacy www.science.org/doi/10.1126/...
Uphold US-Canada science
A partnership can be demanding, and as with any couple, can have good days and bad. The United States–Canada relationship is most definitely having a bad one. It’s difficult to fully comprehend all th...
www.science.org
March 13, 2025 at 7:59 PM
Some thoughts on the new dynamic uncertain status and need for US-Canada Science diplomacy www.science.org/doi/10.1126/...
Reposted by Teresa Mastracci
Thank you.
We're strongest when we are united.
We're strongest when we are united.
March 9, 2025 at 11:26 PM
Thank you.
We're strongest when we are united.
We're strongest when we are united.
Reposted by Teresa Mastracci
As federal funding for research is uncertain, we need to diversify funding sources for our PhD students.
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
March 9, 2025 at 9:15 PM
As federal funding for research is uncertain, we need to diversify funding sources for our PhD students.
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
Reposted by Teresa Mastracci
Although obesity & a sedentary lifestyle are considerable contributors, research over the last 25 years has shown that type 2 #diabetes develops on a predisposing #genetic background, with family & twin studies indicating considerable heritability thelancet.com/journals/lan... #T2D
#MedSky #EndoSky
#MedSky #EndoSky
Dissection of type 2 diabetes: a genetic perspective
Diabetes is a leading cause of global mortality and disability, and its economic burden
is substantial. This Review focuses on type 2 diabetes, which makes up 90–95% of all
diabetes cases. Type 2 diab...
thelancet.com
March 8, 2025 at 1:39 PM
We stand up for science!!
March 7, 2025 at 7:13 PM
We stand up for science!!
Reposted by Teresa Mastracci
March 7, 2025 at 7:01 PM
Thank you #nPOD — I remain speechless!! this meeting never disappoints and has become one that I look forward to every year to challenge thinking, expand my love of science (if that’s even possible!) and remind me of the warmth and generosity of friends and colleagues #nPOD2025 #sciencematters
March 5, 2025 at 4:10 PM
Thank you #nPOD — I remain speechless!! this meeting never disappoints and has become one that I look forward to every year to challenge thinking, expand my love of science (if that’s even possible!) and remind me of the warmth and generosity of friends and colleagues #nPOD2025 #sciencematters
Reposted by Teresa Mastracci
On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. www.cell.com/cell-metabol...
March 4, 2025 at 7:41 PM
On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. www.cell.com/cell-metabol...
Reposted by Teresa Mastracci
✋🛑 Scroll Checkpoint!
Feeling a little stressed? Give your mind a break with some ✨ Soothing Science ✨ featuring one of our stem cell lines.
🔊 Sound on for some tranquil audio
🧪
Feeling a little stressed? Give your mind a break with some ✨ Soothing Science ✨ featuring one of our stem cell lines.
🔊 Sound on for some tranquil audio
🧪
March 3, 2025 at 7:49 PM
✋🛑 Scroll Checkpoint!
Feeling a little stressed? Give your mind a break with some ✨ Soothing Science ✨ featuring one of our stem cell lines.
🔊 Sound on for some tranquil audio
🧪
Feeling a little stressed? Give your mind a break with some ✨ Soothing Science ✨ featuring one of our stem cell lines.
🔊 Sound on for some tranquil audio
🧪
Reposted by Teresa Mastracci
Some good news: The Federal Register has just posted NIH study sections, which are to meet in late March.
NIH announces some key grant-review meetings will restart in late March | Science | AAAS www.science.org/content/arti...
NIH announces some key grant-review meetings will restart in late March | Science | AAAS www.science.org/content/arti...
NIH announces some key grant-review meetings will restart in late March
Trump policy blocking required notices has frozen reviews of thousands of grants
www.science.org
March 3, 2025 at 7:33 PM
Some good news: The Federal Register has just posted NIH study sections, which are to meet in late March.
NIH announces some key grant-review meetings will restart in late March | Science | AAAS www.science.org/content/arti...
NIH announces some key grant-review meetings will restart in late March | Science | AAAS www.science.org/content/arti...
New publication from the #Mastracci lab,which outlines 2 techniques that measure changes in mRNA #translation: polysome profiling and puromycin incorporation. We have detailed step-by-step protocols, including all the needed reagents to execute these techniques!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Analysis of translational regulation using polysome profiling and puromycin incorporation
Translation is the process of decoding an mRNA transcript to permit the synthesis of a protein. This process occurs in three steps: initiation, elonga…
www.sciencedirect.com
February 19, 2025 at 9:06 PM
New publication from the #Mastracci lab,which outlines 2 techniques that measure changes in mRNA #translation: polysome profiling and puromycin incorporation. We have detailed step-by-step protocols, including all the needed reagents to execute these techniques!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Teresa Mastracci
I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦
Contact info on my website.
Contact info on my website.
February 15, 2025 at 4:40 PM
I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦
Contact info on my website.
Contact info on my website.
Reposted by Teresa Mastracci
When people see the maple leaf, they see possibility. They see freedom. They see a helping hand.
They see Canada, and the best of our values.
Happy 60th to our flag. 🇨🇦
They see Canada, and the best of our values.
Happy 60th to our flag. 🇨🇦
February 15, 2025 at 5:23 PM
When people see the maple leaf, they see possibility. They see freedom. They see a helping hand.
They see Canada, and the best of our values.
Happy 60th to our flag. 🇨🇦
They see Canada, and the best of our values.
Happy 60th to our flag. 🇨🇦
Reposted by Teresa Mastracci
Happy #ValentinesDay to all of our beloved developmental biologists from the ISDB team. Here is a heart made out of some migrating immune cells. It's only right that they are in pink. Do you spot another heart somewhere in the photo? 😌 💗
February 14, 2025 at 10:06 PM
Happy #ValentinesDay to all of our beloved developmental biologists from the ISDB team. Here is a heart made out of some migrating immune cells. It's only right that they are in pink. Do you spot another heart somewhere in the photo? 😌 💗
Reposted by Teresa Mastracci
Neuronal growth cones videoed through a differential interference contrast (DIC) microscope. #CellBiology #Science #Biology #microscopy
February 14, 2025 at 6:35 PM
Neuronal growth cones videoed through a differential interference contrast (DIC) microscope. #CellBiology #Science #Biology #microscopy
Reposted by Teresa Mastracci
Reposted by Teresa Mastracci
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 9:58 PM
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Reposted by Teresa Mastracci
A 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗿𝗲𝘀𝘁 is a group of ectodermal cells that are pinched off during neural tube closure. The neural crest migrates to various locations to contribute to diverse tissues, including melanocytes, craniofacial bones, and peripheral-nerve ganglia.
#MedSky #ScienceSky
#MedSky #ScienceSky
February 8, 2025 at 9:15 PM
A 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗿𝗲𝘀𝘁 is a group of ectodermal cells that are pinched off during neural tube closure. The neural crest migrates to various locations to contribute to diverse tissues, including melanocytes, craniofacial bones, and peripheral-nerve ganglia.
#MedSky #ScienceSky
#MedSky #ScienceSky
Reposted by Teresa Mastracci
ICYMI: Commentary on "mechanism" in dev bio
Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level
journals.biologists.com/dev/article/...
Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level
journals.biologists.com/dev/article/...
A case for broadening our view of mechanism in developmental biology
ABSTRACT. Developmental biologists can perform studies that describe a phenomenon (descriptive work) and/or explain how the phenomenon works (mechanistic work). There is a prevalent perception that mo...
journals.biologists.com
February 5, 2025 at 10:56 AM
ICYMI: Commentary on "mechanism" in dev bio
Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level
journals.biologists.com/dev/article/...
Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level
journals.biologists.com/dev/article/...
Reposted by Teresa Mastracci
Birth defects are the #1 cause of death in the first year of life (🧵). Birth defects kill more than twice as many children as cancer. Birth defects are diseases of developmental biology. Here are CDC statistics for 2021. 1/5
wisqars.cdc.gov/pdfs/leading...
wisqars.cdc.gov/pdfs/leading...
February 4, 2025 at 3:07 PM
Birth defects are the #1 cause of death in the first year of life (🧵). Birth defects kill more than twice as many children as cancer. Birth defects are diseases of developmental biology. Here are CDC statistics for 2021. 1/5
wisqars.cdc.gov/pdfs/leading...
wisqars.cdc.gov/pdfs/leading...
Reposted by Teresa Mastracci
Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine.
@socdevbio.bsky.social
@socdevbio.bsky.social
February 1, 2025 at 3:03 PM
Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine.
@socdevbio.bsky.social
@socdevbio.bsky.social
I will defend the importance of science until I’m blue in the face. As a society we need science to help us maintain health and resolve disease but we also need it to answer the simple everyday questions that can make our lives easier and happier. Case in point….
arxiv.org/abs/2501.00536
arxiv.org/abs/2501.00536
Phase behavior of Cacio and Pepe sauce
"Pasta alla Cacio e pepe" is a traditional Italian dish made with pasta, pecorino cheese, and pepper. Despite its simple ingredient list, achieving the perfect texture and creaminess of the sauce can ...
arxiv.org
January 25, 2025 at 11:34 AM
I will defend the importance of science until I’m blue in the face. As a society we need science to help us maintain health and resolve disease but we also need it to answer the simple everyday questions that can make our lives easier and happier. Case in point….
arxiv.org/abs/2501.00536
arxiv.org/abs/2501.00536