Florian Buchkremer
@swissnephro.bsky.social
Nephrologist. Views are my own. #UrinarySediment #Hyponatremia #POCUS
👉 www.swissnephro.org
👉 www.swissnephro.org
Pinned
My favorite birding pick from this years #KidneyWk
Anna’s Hummingbird 🚹
(Calypte anna)
10-2024, San Diego
Anna’s Hummingbird 🚹
(Calypte anna)
10-2024, San Diego
Reposted by Florian Buchkremer
GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD - American Journal of Kidney Diseases www.ajkd.org/article/S027...
GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD
Opportunistic CT-based screening is the practice of exploiting incidental imaging
data for prevention, risk profiling, or presymptomatic detection of relevant disease
unrelated to the purpose for whic...
www.ajkd.org
November 12, 2025 at 6:28 PM
GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD - American Journal of Kidney Diseases www.ajkd.org/article/S027...
Reposted by Florian Buchkremer
Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself)
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
November 6, 2025 at 6:39 PM
Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself)
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
Reposted by Florian Buchkremer
Nephrologists deported
Grants defunded
NIDDK folded into National Institute of body parts
AHRQ demolished
Now this…
When are our organizations going to speak up?
#NephSky
Grants defunded
NIDDK folded into National Institute of body parts
AHRQ demolished
Now this…
When are our organizations going to speak up?
#NephSky
July 2, 2025 at 1:37 AM
Nephrologists deported
Grants defunded
NIDDK folded into National Institute of body parts
AHRQ demolished
Now this…
When are our organizations going to speak up?
#NephSky
Grants defunded
NIDDK folded into National Institute of body parts
AHRQ demolished
Now this…
When are our organizations going to speak up?
#NephSky
Reposted by Florian Buchkremer
Hilarious (and sobering) essay on the use of AI in medical research & manuscript writing
Read the whole thing!
John Daugirdas has been on the cutting edge of tech in meded before #MedEd was thing
onlinelibrary.wiley.com/doi/10.1111/...
#MedSky #NephSky
Read the whole thing!
John Daugirdas has been on the cutting edge of tech in meded before #MedEd was thing
onlinelibrary.wiley.com/doi/10.1111/...
#MedSky #NephSky
Use of Artificial Intelligence in Scientific Writing. The Danger of Trying Too Hard to Please
The author describes his experience using several artificial intelligence programs to assist in the process of editing or preparing manuscripts for publication. While the programs were very useful to...
onlinelibrary.wiley.com
June 13, 2025 at 3:37 PM
Hilarious (and sobering) essay on the use of AI in medical research & manuscript writing
Read the whole thing!
John Daugirdas has been on the cutting edge of tech in meded before #MedEd was thing
onlinelibrary.wiley.com/doi/10.1111/...
#MedSky #NephSky
Read the whole thing!
John Daugirdas has been on the cutting edge of tech in meded before #MedEd was thing
onlinelibrary.wiley.com/doi/10.1111/...
#MedSky #NephSky
Reposted by Florian Buchkremer
I am BEGGING major journals to stop platforming the current administration's politicization of the FDA, CDC, vaccines, etc
This sort of evidence-lite, glitzy puff piece seems appropriate for a newspaper OpEd, not a medical journal.
Platforming it in a major journal gives it the veneer of validity.
This sort of evidence-lite, glitzy puff piece seems appropriate for a newspaper OpEd, not a medical journal.
Platforming it in a major journal gives it the veneer of validity.
Viewpoint: The US FDA aims to expedite drug approvals and address childhood chronic diseases by leveraging innovation, food safety, #AI, and big data.
ja.ma/45jWnNS #MedSky
ja.ma/45jWnNS #MedSky
June 10, 2025 at 5:06 PM
I am BEGGING major journals to stop platforming the current administration's politicization of the FDA, CDC, vaccines, etc
This sort of evidence-lite, glitzy puff piece seems appropriate for a newspaper OpEd, not a medical journal.
Platforming it in a major journal gives it the veneer of validity.
This sort of evidence-lite, glitzy puff piece seems appropriate for a newspaper OpEd, not a medical journal.
Platforming it in a major journal gives it the veneer of validity.
Reposted by Florian Buchkremer
It's been a long journey but today we can share the methods and rationale for the #ACHIEVEtrial (Spiro vs placebo for patients with kidney failure receiving maintenance dialysis) and tomorrow we share the results at #era25
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
The Aldosterone Blockade for Health Improvement Evaluation in End-Stage Renal Disease (ACHIEVE) Trial: Rationale and Clinical Research Protocol - Michael Walsh, David Collister, Martin Gallagher, Patr...
Background: The mineralocorticoid aldosterone may contribute to the risk of cardiovascular morbidity and mortality in patients receiving maintenance dialysis. W...
journals.sagepub.com
June 5, 2025 at 7:44 AM
It's been a long journey but today we can share the methods and rationale for the #ACHIEVEtrial (Spiro vs placebo for patients with kidney failure receiving maintenance dialysis) and tomorrow we share the results at #era25
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Reposted by Florian Buchkremer
Update to our supersaturation and kidney stone risk assessment tool:
We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea!
ukidney.com/calculators/...
We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea!
ukidney.com/calculators/...
May 29, 2025 at 4:26 PM
Update to our supersaturation and kidney stone risk assessment tool:
We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea!
ukidney.com/calculators/...
We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea!
ukidney.com/calculators/...
Reposted by Florian Buchkremer
This systematic review shows blood pressure reduction from sodium reduction in the context of antihypertensive medication use.
Blood Pressure–Lowering Medications, Sodium Reduction, and Blood Pressure | Hypertension www.ahajournals.org/doi/10.1161/...
Blood Pressure–Lowering Medications, Sodium Reduction, and Blood Pressure | Hypertension www.ahajournals.org/doi/10.1161/...
Blood Pressure–Lowering Medications, Sodium Reduction, and Blood Pressure | Hypertension
BACKGROUND: Both blood pressure–lowering medication and sodium reduction are effective in hypertension
control, but whether the effect of sodium reduction differ across blood pressure–lowering
medicat...
www.ahajournals.org
May 29, 2025 at 9:32 AM
This systematic review shows blood pressure reduction from sodium reduction in the context of antihypertensive medication use.
Blood Pressure–Lowering Medications, Sodium Reduction, and Blood Pressure | Hypertension www.ahajournals.org/doi/10.1161/...
Blood Pressure–Lowering Medications, Sodium Reduction, and Blood Pressure | Hypertension www.ahajournals.org/doi/10.1161/...
Reposted by Florian Buchkremer
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
May 13, 2025 at 7:55 PM
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
Reposted by Florian Buchkremer
This is so exciting! The German National Library of Medicine @zbmed.bsky.social just had its first open meeting on the plan for an open & independent PubMed safety net. Here's my write-up @plos.org on the meeting & how institutions & others can help absolutelymaybe.plos.org/2025/05/14/g...
#MedLibs
#MedLibs
Germany's Plan for an Open and Independent PubMed Safety Net - Absolutely Maybe
A few months ago, I wrote about reasons to be concerned about the reliability of PubMed under the new regime at the…
absolutelymaybe.plos.org
May 14, 2025 at 3:41 PM
This is so exciting! The German National Library of Medicine @zbmed.bsky.social just had its first open meeting on the plan for an open & independent PubMed safety net. Here's my write-up @plos.org on the meeting & how institutions & others can help absolutelymaybe.plos.org/2025/05/14/g...
#MedLibs
#MedLibs
Reposted by Florian Buchkremer
Amiloride was noninferior to spironolactone in lowering home systolic blood pressure at 12 weeks.
https://ja.ma/42XMGD9
https://ja.ma/42XMGD9
May 14, 2025 at 4:00 PM
Amiloride was noninferior to spironolactone in lowering home systolic blood pressure at 12 weeks.
https://ja.ma/42XMGD9
https://ja.ma/42XMGD9
Reposted by Florian Buchkremer
RBC cast - brightfield with SM stain - from new case of MPA - #UrineMicroscopy #UrinarySediment
May 13, 2025 at 3:04 AM
RBC cast - brightfield with SM stain - from new case of MPA - #UrineMicroscopy #UrinarySediment
Reposted by Florian Buchkremer
Thrilled to unveil the first-in-human use of #apelin in #hyponatremia at #ECE2025 in Copenhagen.
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
May 12, 2025 at 4:19 PM
Thrilled to unveil the first-in-human use of #apelin in #hyponatremia at #ECE2025 in Copenhagen.
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
This is absolutely amazing!
👏👏👏👏👏👏👏👏👏👏👏
👏👏👏👏👏👏👏👏👏👏👏
🧵 Introducing the EQUIL2 Urinary Supersaturation Calculator
A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.
ukidney.com/calculators/...
1/3
A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.
ukidney.com/calculators/...
1/3
EQUIL2 - Urinary Supersaturation Calculator
Calculate urinary supersaturation based on EQUIL2 methodology.
ukidney.com
May 12, 2025 at 8:10 PM
This is absolutely amazing!
👏👏👏👏👏👏👏👏👏👏👏
👏👏👏👏👏👏👏👏👏👏👏
Reposted by Florian Buchkremer
🧵 Introducing the EQUIL2 Urinary Supersaturation Calculator
A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.
ukidney.com/calculators/...
1/3
A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.
ukidney.com/calculators/...
1/3
EQUIL2 - Urinary Supersaturation Calculator
Calculate urinary supersaturation based on EQUIL2 methodology.
ukidney.com
May 12, 2025 at 4:25 PM
🧵 Introducing the EQUIL2 Urinary Supersaturation Calculator
A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.
ukidney.com/calculators/...
1/3
A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.
ukidney.com/calculators/...
1/3
Reposted by Florian Buchkremer
Reposted by Florian Buchkremer
Another @nejm.org simultaneous publication during #ISNWCN, about xenotransplantation
Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease
www.nejm.org/doi/full/10....
Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease
www.nejm.org/doi/full/10....
Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease | NEJM
Xenotransplantation offers a potential solution to the organ shortage crisis. A 62-year-old
hemodialysis-dependent man with long-standing diabetes, advanced vasculopathy, and
marked dialysis-access...
www.nejm.org
February 7, 2025 at 9:45 AM
Another @nejm.org simultaneous publication during #ISNWCN, about xenotransplantation
Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease
www.nejm.org/doi/full/10....
Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease
www.nejm.org/doi/full/10....
Reposted by Florian Buchkremer
#UTHR United Therapeutics Corporation Announces FDA Clearance of its Investigational New Drug Application for the UKidney Xenotransplantation Clinical Trial
https://www.stocktitan.net/news/UTHR/united-therapeutics-corporation-announces-fda-clearance-of-its-i9jdr5owbet7.html
https://www.stocktitan.net/news/UTHR/united-therapeutics-corporation-announces-fda-clearance-of-its-i9jdr5owbet7.html
Revolutionary Pig-to-Human Kidney Transplant Trial Gets Historic FDA Green Light
United Therapeutics advances xenotransplantation with FDA clearance for UKidney™ human trials, offering hope to 557,000+ dialysis patients. First transplants planned for 2025.
www.stocktitan.net
February 3, 2025 at 12:00 PM
#UTHR United Therapeutics Corporation Announces FDA Clearance of its Investigational New Drug Application for the UKidney Xenotransplantation Clinical Trial
https://www.stocktitan.net/news/UTHR/united-therapeutics-corporation-announces-fda-clearance-of-its-i9jdr5owbet7.html
https://www.stocktitan.net/news/UTHR/united-therapeutics-corporation-announces-fda-clearance-of-its-i9jdr5owbet7.html
Reposted by Florian Buchkremer
Auschwitz was at the end of a long process. It did not start from gas chambers.
This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder.
Auschwitz took time.
This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder.
Auschwitz took time.
January 27, 2025 at 10:00 AM
Auschwitz was at the end of a long process. It did not start from gas chambers.
This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder.
Auschwitz took time.
This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder.
Auschwitz took time.
Reposted by Florian Buchkremer
This is interesting
Aerococcus sanquinicola and Aerococcus urinae in the urine metabolizing creatinine resulting in false low readings with implications for UPCR, UACR and 24 hour urine creatinine collections
www.kireports.org/article/S246...
Aerococcus sanquinicola and Aerococcus urinae in the urine metabolizing creatinine resulting in false low readings with implications for UPCR, UACR and 24 hour urine creatinine collections
www.kireports.org/article/S246...
A Patient With Unmeasurable Urine Creatinine
A 74-year-old female presented with proteinuria at the nephrology department. Her
medical history noted multiple cerebrovascular accidents. Her medication included
a daily dosage of clopidogrel 75 mg,...
www.kireports.org
January 20, 2025 at 4:44 AM
This is interesting
Aerococcus sanquinicola and Aerococcus urinae in the urine metabolizing creatinine resulting in false low readings with implications for UPCR, UACR and 24 hour urine creatinine collections
www.kireports.org/article/S246...
Aerococcus sanquinicola and Aerococcus urinae in the urine metabolizing creatinine resulting in false low readings with implications for UPCR, UACR and 24 hour urine creatinine collections
www.kireports.org/article/S246...
Reposted by Florian Buchkremer
This is me : this is how I scan electronic health records when I try to find the cause of a kidney issue or sort out a complicated medical history.
I have refrained from using the phrase "binary search" with my trainees as many will tune out because "computers," but perhaps I should start?
I have refrained from using the phrase "binary search" with my trainees as many will tune out because "computers," but perhaps I should start?
December 11, 2024 at 12:07 PM
This is me : this is how I scan electronic health records when I try to find the cause of a kidney issue or sort out a complicated medical history.
I have refrained from using the phrase "binary search" with my trainees as many will tune out because "computers," but perhaps I should start?
I have refrained from using the phrase "binary search" with my trainees as many will tune out because "computers," but perhaps I should start?
Reposted by Florian Buchkremer
Doing a fistulagram and the wire goes through a 99% blocked stenosis on the first try! @asdinnews.bsky.social
December 10, 2024 at 2:06 PM
Doing a fistulagram and the wire goes through a 99% blocked stenosis on the first try! @asdinnews.bsky.social