https://behindthebioinformatics.substack.com/
www.nature.com/articles/s41...
Prewritten fates: how space, stress, and systemic signals shape cancer
open.substack.com/pub/behindth...
#Immunology #Epigenetics #TrajectoryInference #Cancer #SystemsBiology #Spatial #Singlecell
Prewritten fates: how space, stress, and systemic signals shape cancer
open.substack.com/pub/behindth...
#Immunology #Epigenetics #TrajectoryInference #Cancer #SystemsBiology #Spatial #Singlecell
www.nature.com/articles/d41...
www.nature.com/articles/d41...
How cells and whales keep control
open.substack.com/pub/behindth...
#SpatialOmics #Immunotherapy #DeepLearning #Genomics #SystemsBiology
How cells and whales keep control
open.substack.com/pub/behindth...
#SpatialOmics #Immunotherapy #DeepLearning #Genomics #SystemsBiology
"From aging clones to generative genomics: evolution meets AI in modern biology"
open.substack.com/pub/behindth...
#AIinBiology #SingleCell #SpatialOmics #MultiOmics #DrugDiscovery #Genomics #DeepLearning
"From aging clones to generative genomics: evolution meets AI in modern biology"
open.substack.com/pub/behindth...
#AIinBiology #SingleCell #SpatialOmics #MultiOmics #DrugDiscovery #Genomics #DeepLearning
Multi-omics integration and batch correction using a modality-agnostic deep learning framework www.biorxiv.org/content/10.1...
#SingleCell #SpatialOmics #DeepLearning
Multi-omics integration and batch correction using a modality-agnostic deep learning framework www.biorxiv.org/content/10.1...
#SingleCell #SpatialOmics #DeepLearning
open.substack.com/pub/behindth...
#Aging #CancerMetabolism #SingleCell #SpatialOmics #AIinBiology #Genomics
open.substack.com/pub/behindth...
#Aging #CancerMetabolism #SingleCell #SpatialOmics #AIinBiology #Genomics
SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life.
www.biorxiv.org/content/10.1...
SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life.
www.biorxiv.org/content/10.1...
🧠 DNA that learns like a neural net
🧬 SMAD4 flips roles by organ in PDAC
🧫 scPortrait + BAG-seq + RAEFISH push imaging & multi-omics forward
🤖 scKAN & Tangram2 make #single-cell #AI interpretable & #spatial
open.substack.com/pub/behindth...
🧠 DNA that learns like a neural net
🧬 SMAD4 flips roles by organ in PDAC
🧫 scPortrait + BAG-seq + RAEFISH push imaging & multi-omics forward
🤖 scKAN & Tangram2 make #single-cell #AI interpretable & #spatial
open.substack.com/pub/behindth...
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Featuring, among others:
- A Perspective on #drugconjugates
- #immunotherapy studies
- research on GBM invasion
- method for #singlecell analyses of #CTCs
🔗 www.nature.com/natcancer/vo...
Details & apply by 13/10/25: tinyurl.com/4shdw8dk
Details & apply by 13/10/25: tinyurl.com/4shdw8dk
🧠 Bladder cancer co-opts macrophages
👁️ OSK factors rejuvenate vision via GSTA4
🧬 SPP1 sustains aggressive pancreatic tumors
📍 AMICI + EpiAgent + scFME push spatial & single-cell AI forward
#Cancer #Aging #SingleCell #Spatial #AI
open.substack.com/pub/behindth...
🧠 Bladder cancer co-opts macrophages
👁️ OSK factors rejuvenate vision via GSTA4
🧬 SPP1 sustains aggressive pancreatic tumors
📍 AMICI + EpiAgent + scFME push spatial & single-cell AI forward
#Cancer #Aging #SingleCell #Spatial #AI
open.substack.com/pub/behindth...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
🧬 DNA methylation as both cancer driver & evolutionary clock
🧫 SPACE brings CRISPR screens into 3D tissues
🤖 AI designs functional phages
🧠 SCLC plugs into brain circuits
open.substack.com/pub/behindth...
#Cancer #SingleCell #SpatialOmics #AI #Epigenetics
🧬 DNA methylation as both cancer driver & evolutionary clock
🧫 SPACE brings CRISPR screens into 3D tissues
🤖 AI designs functional phages
🧠 SCLC plugs into brain circuits
open.substack.com/pub/behindth...
#Cancer #SingleCell #SpatialOmics #AI #Epigenetics
Learn more: drive.google.com/file/d/15mMR...
#postdocjobs #AI #BiomedicalScience
Learn more: drive.google.com/file/d/15mMR...
#postdocjobs #AI #BiomedicalScience
#CancerResearch #SpatialOmics #CompBio
open.substack.com/pub/behindth...
#CancerResearch #SpatialOmics #CompBio
open.substack.com/pub/behindth...
- Tumor architecture + nuclear shape fuel CRC heterogeneity
- Viral infections awaken dormant #cancer
- Engineered bacteria launch an oncolytic virus
- Axonal injury drives #glioblastoma
#SingleCell #SpatialOmics #SystemsBiology
open.substack.com/pub/behindth...
- Tumor architecture + nuclear shape fuel CRC heterogeneity
- Viral infections awaken dormant #cancer
- Engineered bacteria launch an oncolytic virus
- Axonal injury drives #glioblastoma
#SingleCell #SpatialOmics #SystemsBiology
open.substack.com/pub/behindth...
- Reprogramming CAFs to boost immunotherapy
- When & how neural nets learn DNA motifs
- Decipher: a generative model for derailed cell states
- Tissue-of-origin constraints on metastasis
- Spatial deconvolution methods adapt to ATAC
open.substack.com/pub/behindth...
- Reprogramming CAFs to boost immunotherapy
- When & how neural nets learn DNA motifs
- Decipher: a generative model for derailed cell states
- Tissue-of-origin constraints on metastasis
- Spatial deconvolution methods adapt to ATAC
open.substack.com/pub/behindth...