Reposted by Chris Marine Lab
Registration for Cancer Cell Plasticity closes on Monday 03 November!
Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels:
eacr.org/conference/c...
Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels:
eacr.org/conference/c...
October 29, 2025 at 9:03 AM
Registration for Cancer Cell Plasticity closes on Monday 03 November!
Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels:
eacr.org/conference/c...
Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels:
eacr.org/conference/c...
Just like there are good and bad macrophages..., there are good and bad NK cells!! This has profound therapeutic implications, far beyond oncology! Thanks to CD for highlighting both papers and the superb and efficient editorial work! Thanks to our collaborators (especially Zihai Li) and funders!
Now online in Cancer Discovery for the #EACR2025 presentation by @marinelab.bsky.social: Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype doi.org/10.1158/2159... @vib-ccb.bsky.social @pozniakjoanna.bsky.social
September 9, 2025 at 6:27 PM
Just like there are good and bad macrophages..., there are good and bad NK cells!! This has profound therapeutic implications, far beyond oncology! Thanks to CD for highlighting both papers and the superb and efficient editorial work! Thanks to our collaborators (especially Zihai Li) and funders!
Unmissable for those working on melanoma and beyond.
The SMR 2025 Annual Congress (Amsterdam Oct 25-28) covers basic, preclinical & translational melanoma research of international top investigators. It is a very enjoyable conference with top faculty and now improved with ample opportunity for young investigators to network. Join us! smrcongress.org
Society Melanoma Research Congress
smrcongress.org
July 9, 2025 at 7:33 PM
Unmissable for those working on melanoma and beyond.
Reposted by Chris Marine Lab
Now online in Cancer Discovery for the #EACR2025 presentation by @marinelab.bsky.social: Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype doi.org/10.1158/2159... @vib-ccb.bsky.social @pozniakjoanna.bsky.social
June 18, 2025 at 1:47 PM
Now online in Cancer Discovery for the #EACR2025 presentation by @marinelab.bsky.social: Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype doi.org/10.1158/2159... @vib-ccb.bsky.social @pozniakjoanna.bsky.social
Very excited to see our new study out today - just in time for my talk annual EACR conference @helloeacr.bsky.social
Christophe Marine @marinelab.bsky.social @vib-ccb.bsky.social presenting his hot-off-the-presses Cancer Discovery paper today at #EACR2025!
June 18, 2025 at 11:12 AM
Very excited to see our new study out today - just in time for my talk annual EACR conference @helloeacr.bsky.social
rdcu.be/emi9N
Fishing for Metastasis Initiating Cells (MICs): we summarize here a heroic effort from Christoph Klein and Melanie Werner-Klein labs, which describes a MIC population in lymph nodes and how these cells evade immune attack. #metastasis #melanoma #extracellularvesicles #cancerprevention
Fishing for Metastasis Initiating Cells (MICs): we summarize here a heroic effort from Christoph Klein and Melanie Werner-Klein labs, which describes a MIC population in lymph nodes and how these cells evade immune attack. #metastasis #melanoma #extracellularvesicles #cancerprevention
Fishing for melanoma metastasis-initiating cells in lymph nodes
Nature Cancer - The complex nature of metastasis-initiating cells (MICs) has long hindered our understanding of how cancer spreads and how to prevent it. A study now identifies a potential MIC...
rdcu.be
May 17, 2025 at 8:25 AM
rdcu.be/emi9N
Fishing for Metastasis Initiating Cells (MICs): we summarize here a heroic effort from Christoph Klein and Melanie Werner-Klein labs, which describes a MIC population in lymph nodes and how these cells evade immune attack. #metastasis #melanoma #extracellularvesicles #cancerprevention
Fishing for Metastasis Initiating Cells (MICs): we summarize here a heroic effort from Christoph Klein and Melanie Werner-Klein labs, which describes a MIC population in lymph nodes and how these cells evade immune attack. #metastasis #melanoma #extracellularvesicles #cancerprevention
Reposted by Chris Marine Lab
“Science has no passport, no gender, no ethnicity, no political party.”
EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent.
In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.
EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent.
In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.
May 6, 2025 at 11:26 AM
“Science has no passport, no gender, no ethnicity, no political party.”
EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent.
In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.
EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent.
In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.
We are really looking forward to hosting YOU and these amazing speakers in Leuven. Whether you are a young trainee, an experienced postdoc or a leader in the field, please join us (you will not regret this!).
The VIB Conference on Tumor Heterogeneity, Plasticity, & Therapy is back (3rd edition) on Dec 10-12 in Leuven! Join us at #THPT25 for 2 days of pioneering research & discussions on #tumorbiology and #cancertherapy resistance. Be part of the conversation: vibbio.tech/3DLsomq.
@vib-ccb.bsky.social
@vib-ccb.bsky.social
April 29, 2025 at 12:57 PM
We are really looking forward to hosting YOU and these amazing speakers in Leuven. Whether you are a young trainee, an experienced postdoc or a leader in the field, please join us (you will not regret this!).
An important step towards personalised (combination) cancer treatments. vib.be/en#/ We are very excited about this project! Thanks to Oliver Bechter and his team and Presage for their trust and vision.
April 1, 2025 at 10:19 AM
An important step towards personalised (combination) cancer treatments. vib.be/en#/ We are very excited about this project! Thanks to Oliver Bechter and his team and Presage for their trust and vision.
Great talk from my friend and colleague @cedric-blanpain.bsky.social (Chemoresistance) at the @helloeacr.bsky.social conference on Drug Tolerant Persister Cells (Lyon, France). Thanks to the organizers for this exciting event.
March 19, 2025 at 12:08 AM
Great talk from my friend and colleague @cedric-blanpain.bsky.social (Chemoresistance) at the @helloeacr.bsky.social conference on Drug Tolerant Persister Cells (Lyon, France). Thanks to the organizers for this exciting event.
Please join us for this exciting event!!! Very much looking forward to the great talks and discussions on this 🔥 topic
Registration and abstract submission is now open for Cancer Cell Plasticity: Cracking the Code of Adaptation and Survival!
Join us online on 02-03 December for a jam-packed programme discussing the latest discoveries in this field.
eacr.org/conference/c...
Join us online on 02-03 December for a jam-packed programme discussing the latest discoveries in this field.
eacr.org/conference/c...
March 14, 2025 at 2:57 PM
Please join us for this exciting event!!! Very much looking forward to the great talks and discussions on this 🔥 topic
Our latest piece "Decoding Melanoma’s Cellular Mosaic to Unlock Immunotherapy Potential" is available online: authors.elsevier.com/a/1khFK3QxxS... and will soon be published in @cp-trendscellbio.bsky.social. Thanks to @pozniakjoanna.bsky.social for taking the lead! Our Cover design proposal is below
March 1, 2025 at 4:34 AM
Our latest piece "Decoding Melanoma’s Cellular Mosaic to Unlock Immunotherapy Potential" is available online: authors.elsevier.com/a/1khFK3QxxS... and will soon be published in @cp-trendscellbio.bsky.social. Thanks to @pozniakjoanna.bsky.social for taking the lead! Our Cover design proposal is below
Reposted by Chris Marine Lab
Breaks are key to relaxed & unwind between sessions! This afternoon, @juliensage.bsky.social hit the courts with @marinelab.bsky.social & Lukas Dow - what better way to reset than a (maybe not so) friendly game of tennis🎾 #AMC25
February 28, 2025 at 10:40 PM
Breaks are key to relaxed & unwind between sessions! This afternoon, @juliensage.bsky.social hit the courts with @marinelab.bsky.social & Lukas Dow - what better way to reset than a (maybe not so) friendly game of tennis🎾 #AMC25
Our excellent host, Julien Sage, sharing a surprising/unexpected role for T cells in the biology of small cell lung cancer …thanks Julien and Kevin for organising such a great @fusionconf.bsky.social (mouse models of cancer) conference!!
February 28, 2025 at 8:53 PM
Our excellent host, Julien Sage, sharing a surprising/unexpected role for T cells in the biology of small cell lung cancer …thanks Julien and Kevin for organising such a great @fusionconf.bsky.social (mouse models of cancer) conference!!
Reposted by Chris Marine Lab
We took a deep dive into cancer progressions & metastasis this morning at #AMC25:
🧬Chris Marine on melanoma progression & therapy resistance
🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models
🫁Katie Politi on progression & resistance in lung cancer
🌊Plus an exciting Catamaran tour⛵️
🧬Chris Marine on melanoma progression & therapy resistance
🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models
🫁Katie Politi on progression & resistance in lung cancer
🌊Plus an exciting Catamaran tour⛵️
February 27, 2025 at 9:58 PM
We took a deep dive into cancer progressions & metastasis this morning at #AMC25:
🧬Chris Marine on melanoma progression & therapy resistance
🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models
🫁Katie Politi on progression & resistance in lung cancer
🌊Plus an exciting Catamaran tour⛵️
🧬Chris Marine on melanoma progression & therapy resistance
🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models
🫁Katie Politi on progression & resistance in lung cancer
🌊Plus an exciting Catamaran tour⛵️
So cool!!
🔈We've got the cover of the 2nd NG issue for 2025🙌
Read about the cover: In the comment👇
Also check out our research briefing🚨 (link below):
nature.com/articles/s41...
nature.com/articles/s41...
Read about the cover: In the comment👇
Also check out our research briefing🚨 (link below):
nature.com/articles/s41...
nature.com/articles/s41...
February 12, 2025 at 9:59 PM
So cool!!
So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!
Thrilled to share my 1st brainchild, out today @naturegenet.bsky.social 🚀 Been hearing a lot about fetal-like states lately? We uncover the molecular mechanisms, functional significance and clinical relevance of #oncofetal reprogramming in CRC. www.nature.com/articles/s41... (rdcu.be/d9iSN) a 🧵
February 10, 2025 at 3:31 PM
So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!
Reposted by Chris Marine Lab
1) Huge thanks to @guccionelab.bsky.social @nickbarker @marinelab.bsky.social @ggargiul.bsky.social
@owensansom 4 the fantastic collaboration. NIH funding #EarlyStageInvestigator. Towards #BetterTherapeuticStrategies 4 #CRC patients #Oncofetal #CRC #IntratumoralHeterogeneity #PhenotypicPlasticity
@owensansom 4 the fantastic collaboration. NIH funding #EarlyStageInvestigator. Towards #BetterTherapeuticStrategies 4 #CRC patients #Oncofetal #CRC #IntratumoralHeterogeneity #PhenotypicPlasticity
February 10, 2025 at 3:18 PM
1) Huge thanks to @guccionelab.bsky.social @nickbarker @marinelab.bsky.social @ggargiul.bsky.social
@owensansom 4 the fantastic collaboration. NIH funding #EarlyStageInvestigator. Towards #BetterTherapeuticStrategies 4 #CRC patients #Oncofetal #CRC #IntratumoralHeterogeneity #PhenotypicPlasticity
@owensansom 4 the fantastic collaboration. NIH funding #EarlyStageInvestigator. Towards #BetterTherapeuticStrategies 4 #CRC patients #Oncofetal #CRC #IntratumoralHeterogeneity #PhenotypicPlasticity
Congratulations Ginevra and the whole Fendt team! This is very exciting work!
Beyond excited to share that the main work of my PhD on how aspartate signaling drives metastasis is finally out in @nature.com ✨
-> go.nature.com/4gCYtuL
A huge thank to the @fendtlab.bsky.social and all our collaborators for the terrific team work 🙏
A brief 🧵
-> go.nature.com/4gCYtuL
A huge thank to the @fendtlab.bsky.social and all our collaborators for the terrific team work 🙏
A brief 🧵
Aspartate signalling drives lung metastasis via alternative translation - Nature
Aspartate in the tumour environment activates the N-methyl-d-aspartate receptor in cancer cells to induce cellular programmes that increase the aggressiveness of metastasis.
go.nature.com
January 1, 2025 at 7:29 PM
Congratulations Ginevra and the whole Fendt team! This is very exciting work!
Reposted by Chris Marine Lab
End-of-the-year preprint & first 🧵 where the sky is blue! Ever wondered how a cancer driven by a single mutant oncogene becomes molecularly & cellularly heterogeneous? Why metastases share drivers w/primary tumors but are more aggressive?
December 31, 2024 at 1:12 PM
End-of-the-year preprint & first 🧵 where the sky is blue! Ever wondered how a cancer driven by a single mutant oncogene becomes molecularly & cellularly heterogeneous? Why metastases share drivers w/primary tumors but are more aggressive?
Looking for an enthusiastic bioinformatician (long-term postdoctoral follow or staff scientist) interested in cancer/melanoma biology and therapy resistance. Data Science (single-cell, spatial multiomics integration), Machine learning, R, Pyhthon... jobso.id/ik9e
Bioinformatician Postdoctoral Level - VIB
Position summary
The Chris Marine lab at the VIB Center for Cancer Biology (https://ccb.sites.vib.be/en) is actively seeking a skilled bioinformatician proficient in analyzing and integrating single-...
jobso.id
December 17, 2024 at 7:59 AM
Looking for an enthusiastic bioinformatician (long-term postdoctoral follow or staff scientist) interested in cancer/melanoma biology and therapy resistance. Data Science (single-cell, spatial multiomics integration), Machine learning, R, Pyhthon... jobso.id/ik9e
www.cell.com/cell/fulltex...
My first post on BSKY will be a citation from Sydner Brenner (2002): "So genocentric has modern biology become that we have forgotten that the real units of function and structure in an organism are cells and not genes" highlighted by S Quake in this interesting piece.
My first post on BSKY will be a citation from Sydner Brenner (2002): "So genocentric has modern biology become that we have forgotten that the real units of function and structure in an organism are cells and not genes" highlighted by S Quake in this interesting piece.
The cellular dogma
In this essay, I will put forth what I see as a major conceptual challenge for biology
in the next decade, one that is inspired by Crick’s Central Dogma: understanding information
flow in the cell in ...
www.cell.com
November 15, 2024 at 10:33 AM
www.cell.com/cell/fulltex...
My first post on BSKY will be a citation from Sydner Brenner (2002): "So genocentric has modern biology become that we have forgotten that the real units of function and structure in an organism are cells and not genes" highlighted by S Quake in this interesting piece.
My first post on BSKY will be a citation from Sydner Brenner (2002): "So genocentric has modern biology become that we have forgotten that the real units of function and structure in an organism are cells and not genes" highlighted by S Quake in this interesting piece.