Sebastian Streichan
@streichan.bsky.social
Excited about animal and synthetic morphogenesis, light-sheet microscopy, and quantitative biology
Reposted by Sebastian Streichan
Cells can form patterns within themselves just like embryos do. How? Connie Yan's new preprint shows how the anterior-posterior cytoskeleton pattern in Stentor is dictated by regionalized scaffolding proteins
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 19, 2025 at 8:42 AM
Cells can form patterns within themselves just like embryos do. How? Connie Yan's new preprint shows how the anterior-posterior cytoskeleton pattern in Stentor is dictated by regionalized scaffolding proteins
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sebastian Streichan
There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant.
research.pasteur.fr/en/call/mid-...
research.pasteur.fr/en/call/mid-...
Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research
Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...
research.pasteur.fr
November 27, 2025 at 1:38 PM
There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant.
research.pasteur.fr/en/call/mid-...
research.pasteur.fr/en/call/mid-...
Reposted by Sebastian Streichan
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
October 22, 2025 at 10:44 PM
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
Reposted by Sebastian Streichan
So excited to share this as a new junior PI:
My brand-new lab website! 🎉🪰🌀
www.bischofflab.com
Please pass it on to young, motivated researchers looking for PhD positions 😊
And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!
#CellBio #DevBio #PhDjob #PhDposition #Science
My brand-new lab website! 🎉🪰🌀
www.bischofflab.com
Please pass it on to young, motivated researchers looking for PhD positions 😊
And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!
#CellBio #DevBio #PhDjob #PhDposition #Science
November 27, 2025 at 8:26 AM
So excited to share this as a new junior PI:
My brand-new lab website! 🎉🪰🌀
www.bischofflab.com
Please pass it on to young, motivated researchers looking for PhD positions 😊
And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!
#CellBio #DevBio #PhDjob #PhDposition #Science
My brand-new lab website! 🎉🪰🌀
www.bischofflab.com
Please pass it on to young, motivated researchers looking for PhD positions 😊
And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!
#CellBio #DevBio #PhDjob #PhDposition #Science
Reposted by Sebastian Streichan
Boris Shraiman points a physicist’s eye on biological quandaries news.ucsb.edu/2025/022264/... 🧪
Boris Shraiman points a physicist’s eye on biological quandaries
Boris Shraiman is awarded the American Physical Society’s Max Delbrück Prize in Biological Physics.
news.ucsb.edu
November 25, 2025 at 7:38 PM
Boris Shraiman points a physicist’s eye on biological quandaries news.ucsb.edu/2025/022264/... 🧪
Reposted by Sebastian Streichan
📢 Paper alert 📢
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
November 24, 2025 at 5:50 PM
📢 Paper alert 📢
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
Reposted by Sebastian Streichan
Studying cochlear neuroanatomy demands imaging the entire cochlea at subcellular resolution. In our recent study (tinyurl.com/isotropicLSFM), we recorded the cochlea at isotropic resolution across the whole organ, laying the groundwork for what follows…
#lightsheet
#isotropic
#cochlea
#lightsheet
#isotropic
#cochlea
November 20, 2025 at 9:20 PM
Studying cochlear neuroanatomy demands imaging the entire cochlea at subcellular resolution. In our recent study (tinyurl.com/isotropicLSFM), we recorded the cochlea at isotropic resolution across the whole organ, laying the groundwork for what follows…
#lightsheet
#isotropic
#cochlea
#lightsheet
#isotropic
#cochlea
Reposted by Sebastian Streichan
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
November 21, 2025 at 1:07 PM
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Reposted by Sebastian Streichan
Are you a postdoc or assistant professor on the job market? Reminder that our department is hiring! We are a scientifically diverse department looking for a colleague that is excited about science, teaching, and potential collaborations! Please apply by 12/5/25!
November 20, 2025 at 6:52 PM
Are you a postdoc or assistant professor on the job market? Reminder that our department is hiring! We are a scientifically diverse department looking for a colleague that is excited about science, teaching, and potential collaborations! Please apply by 12/5/25!
Reposted by Sebastian Streichan
The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
November 20, 2025 at 6:11 PM
The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
Reposted by Sebastian Streichan
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
Reposted by Sebastian Streichan
Searching for physical principles of morphogenesis
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
November 19, 2025 at 10:28 AM
Searching for physical principles of morphogenesis
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
Reposted by Sebastian Streichan
Aussies, please consider signing this petition to show your support for Australian science. The sector is already on its knees. 🇦🇺 🧪 actionnetwork.org/petitions/cs...
November 19, 2025 at 1:53 AM
Aussies, please consider signing this petition to show your support for Australian science. The sector is already on its knees. 🇦🇺 🧪 actionnetwork.org/petitions/cs...
Reposted by Sebastian Streichan
Curious how mechanics shape the developing eye? 👁️
Join us for your PhD at the interdisciplinary
@lsiexeter.bsky.social to explore early eye morphogenesis
through developmental biology, biophysics and computational modelling.
lsi.exeter.ac.uk/groups/harma...
Supported by @swbiodtp.bsky.social
Join us for your PhD at the interdisciplinary
@lsiexeter.bsky.social to explore early eye morphogenesis
through developmental biology, biophysics and computational modelling.
lsi.exeter.ac.uk/groups/harma...
Supported by @swbiodtp.bsky.social
November 4, 2025 at 4:09 PM
Curious how mechanics shape the developing eye? 👁️
Join us for your PhD at the interdisciplinary
@lsiexeter.bsky.social to explore early eye morphogenesis
through developmental biology, biophysics and computational modelling.
lsi.exeter.ac.uk/groups/harma...
Supported by @swbiodtp.bsky.social
Join us for your PhD at the interdisciplinary
@lsiexeter.bsky.social to explore early eye morphogenesis
through developmental biology, biophysics and computational modelling.
lsi.exeter.ac.uk/groups/harma...
Supported by @swbiodtp.bsky.social
Reposted by Sebastian Streichan
To learn more about this phenomena, check out the original research article (2019) by @shamipourshayan.bsky.social et al!
Open-access 🔗: www.cell.com/cell/fulltex...
Open-access 🔗: www.cell.com/cell/fulltex...
November 16, 2025 at 6:27 PM
To learn more about this phenomena, check out the original research article (2019) by @shamipourshayan.bsky.social et al!
Open-access 🔗: www.cell.com/cell/fulltex...
Open-access 🔗: www.cell.com/cell/fulltex...
Reposted by Sebastian Streichan
Stunning cover to celebrate the incredible work from @loicaroyer.bsky.social's team.
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Our November issue is now live! 🎉
www.nature.com/nmeth/volume...
On the cover, cell tracking in a developing zebrafish embryo visualized using Ultrack. Cover by Alexandre Dizieux, Jordão Bragantini, Loic Royer, Merlin Lange, CZ Biohub. Paper here: www.nature.com/articles/s41...
www.nature.com/nmeth/volume...
On the cover, cell tracking in a developing zebrafish embryo visualized using Ultrack. Cover by Alexandre Dizieux, Jordão Bragantini, Loic Royer, Merlin Lange, CZ Biohub. Paper here: www.nature.com/articles/s41...
November 14, 2025 at 7:23 PM
Stunning cover to celebrate the incredible work from @loicaroyer.bsky.social's team.
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Reposted by Sebastian Streichan
Happy to share our new work from my graduate lab, with friends & colleagues @suewop.bsky.social, Pieter Derksen, Gary Han, Nikolas Claussen, and @streichan.bsky.social! We find that germ layers exhibit persistent, distinct flow patterns during zebrafish gastrulation.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula
During gastrulation, a sequence of complex processes transforms the blastula into a multilayered embryo. Fixed sample analysis has revealed much about how genetic signaling cascades determine the majo...
www.biorxiv.org
November 13, 2025 at 9:17 PM
Happy to share our new work from my graduate lab, with friends & colleagues @suewop.bsky.social, Pieter Derksen, Gary Han, Nikolas Claussen, and @streichan.bsky.social! We find that germ layers exhibit persistent, distinct flow patterns during zebrafish gastrulation.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sebastian Streichan
🧬 New paper alert! We used AFM PeakForce tapping to map the nanoscale topography of the basement membrane in Drosophila wing discs—revealing unexpected fiber-like and self-affine structures. #BasementMembrane #AFM
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
July 19, 2025 at 9:12 AM
🧬 New paper alert! We used AFM PeakForce tapping to map the nanoscale topography of the basement membrane in Drosophila wing discs—revealing unexpected fiber-like and self-affine structures. #BasementMembrane #AFM
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Sebastian Streichan
Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
September 25, 2025 at 1:41 PM
Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Sebastian Streichan
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
November 12, 2025 at 3:35 PM
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
Reposted by Sebastian Streichan
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
Reposted by Sebastian Streichan
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
October 8, 2025 at 1:05 PM
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
Reposted by Sebastian Streichan
Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
October 9, 2025 at 3:27 PM
Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Sebastian Streichan
Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics?
I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
November 2, 2025 at 9:02 AM
Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics?
I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
Reposted by Sebastian Streichan
What are these?
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
October 26, 2025 at 8:55 AM
What are these?
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵