Shashank Shekhar lab
@sshekhr.bsky.social
Prof. Shashank Shekhar @EmoryUniversity, Atlanta, USA
Biophysicist interested in Actin dynamics and ciliary flows.
Departments of Physics, Biochemistry and Cell Biology.
Lab website : www.shekharlab.org
Biophysicist interested in Actin dynamics and ciliary flows.
Departments of Physics, Biochemistry and Cell Biology.
Lab website : www.shekharlab.org
Pinned
Shashank Shekhar lab
@sshekhr.bsky.social
· Nov 15
I am excited and honored to be named 'Cell Scientist to Watch' by Journal of Cell Science @biologists.bsky.social
Grateful to my team and mentors for their support.
Interested in working on actin? Hiring Postdocs/Grad students!
Grateful to my team and mentors for their support.
Interested in working on actin? Hiring Postdocs/Grad students!
Reposted by Shashank Shekhar lab
Reposted by Shashank Shekhar lab
Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon.
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion | PNAS
Intracellular transport of macromolecules is crucial for the proper functioning of
most cellular processes. Although intracellular crowding is know...
www.pnas.org
January 26, 2026 at 9:42 AM
Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon.
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Reposted by Shashank Shekhar lab
Mark your calendars, the Signaling by Adhesion Receptors GRC is June 7 - 12, 2026. We have a terrific program that balances developmental biology, cell polarity, and adhesion and signaling.
Please spread the word!
www.grc.org/signaling-by...
Please spread the word!
www.grc.org/signaling-by...
2026 Signaling by Adhesion Receptors Conference GRC
The 2026 Gordon Research Conference on Signaling by Adhesion Receptors will be held in Manchester, New Hampshire. Apply today to reserve your spot.
www.grc.org
January 15, 2026 at 6:51 PM
Mark your calendars, the Signaling by Adhesion Receptors GRC is June 7 - 12, 2026. We have a terrific program that balances developmental biology, cell polarity, and adhesion and signaling.
Please spread the word!
www.grc.org/signaling-by...
Please spread the word!
www.grc.org/signaling-by...
😅
Today I made a small but momentous start to work in 2026 by changing a single number.
I renamed the file “Papers to write and submit in 2025” to “Papers to write and submit in 2026”.
Stay tuned for more file updates on 1st January 2027.
I renamed the file “Papers to write and submit in 2025” to “Papers to write and submit in 2026”.
Stay tuned for more file updates on 1st January 2027.
January 2, 2026 at 2:10 AM
😅
Go Alex!!
I am beyond excited to announce that the Bisson Lab has a new home!!! Starting January 2026, I will join the Biology Department at Indiana University Bloomington as Associate Professor with tenure.
I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join
[1/4]
I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join
[1/4]
December 26, 2025 at 12:01 AM
Go Alex!!
Reposted by Shashank Shekhar lab
I am beyond excited to announce that the Bisson Lab has a new home!!! Starting January 2026, I will join the Biology Department at Indiana University Bloomington as Associate Professor with tenure.
I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join
[1/4]
I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join
[1/4]
December 24, 2025 at 5:10 PM
I am beyond excited to announce that the Bisson Lab has a new home!!! Starting January 2026, I will join the Biology Department at Indiana University Bloomington as Associate Professor with tenure.
I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join
[1/4]
I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join
[1/4]
Reposted by Shashank Shekhar lab
🚨 POSTDOC OPENING 🚨
NIH-funded Bio-Fluid Mechanics Postdoc in my lab @univmiami.bsky.social
Hofstenia miamia | cilia-driven flows | behavior & neuroscience
Collab w/ Mansi Srivastava @harvard.edu
🕒 Start: Jan–Feb 2026
⏳ 1 yr, renewable | Email me ASAP!
#Postdoc #Biophysics #FluidDynamics
NIH-funded Bio-Fluid Mechanics Postdoc in my lab @univmiami.bsky.social
Hofstenia miamia | cilia-driven flows | behavior & neuroscience
Collab w/ Mansi Srivastava @harvard.edu
🕒 Start: Jan–Feb 2026
⏳ 1 yr, renewable | Email me ASAP!
#Postdoc #Biophysics #FluidDynamics
December 23, 2025 at 6:31 PM
🚨 POSTDOC OPENING 🚨
NIH-funded Bio-Fluid Mechanics Postdoc in my lab @univmiami.bsky.social
Hofstenia miamia | cilia-driven flows | behavior & neuroscience
Collab w/ Mansi Srivastava @harvard.edu
🕒 Start: Jan–Feb 2026
⏳ 1 yr, renewable | Email me ASAP!
#Postdoc #Biophysics #FluidDynamics
NIH-funded Bio-Fluid Mechanics Postdoc in my lab @univmiami.bsky.social
Hofstenia miamia | cilia-driven flows | behavior & neuroscience
Collab w/ Mansi Srivastava @harvard.edu
🕒 Start: Jan–Feb 2026
⏳ 1 yr, renewable | Email me ASAP!
#Postdoc #Biophysics #FluidDynamics
Reposted by Shashank Shekhar lab
Can biological tissues "learn"? Our new preprint shows that epithelial tissues exhibit emergent behaviors akin to unsupervised learning. Local tension remodeling allows cell networks to store long-range memory and program global elasticity properties.
Read more here: www.biorxiv.org/content/10.6...
Read more here: www.biorxiv.org/content/10.6...
December 20, 2025 at 3:56 PM
Can biological tissues "learn"? Our new preprint shows that epithelial tissues exhibit emergent behaviors akin to unsupervised learning. Local tension remodeling allows cell networks to store long-range memory and program global elasticity properties.
Read more here: www.biorxiv.org/content/10.6...
Read more here: www.biorxiv.org/content/10.6...
Reposted by Shashank Shekhar lab
How does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Target cell cortical tension regulates macrophage trogocytosis - Nature Cell Biology
Cornell et al. show that target cells with low cortical tension induce macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high cortical tension tend tow...
www.nature.com
December 15, 2025 at 10:51 PM
How does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Shashank Shekhar lab
The Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at: reckpetersonlab.org.
December 14, 2025 at 4:27 PM
The Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at: reckpetersonlab.org.
Reposted by Shashank Shekhar lab
Interested in cell adhesion, evolution of multicellularity, or developing tools for emerging marine models?
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
December 8, 2025 at 6:37 PM
Interested in cell adhesion, evolution of multicellularity, or developing tools for emerging marine models?
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
Reposted by Shashank Shekhar lab
📢 Deadline approaching fast 📢
to submit an abstract for the great cytoskeleton extravaganza!
to submit an abstract for the great cytoskeleton extravaganza!
Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Structure and Function of the Cytoskeleton
The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …
meetings.embo.org
December 10, 2025 at 4:44 PM
📢 Deadline approaching fast 📢
to submit an abstract for the great cytoskeleton extravaganza!
to submit an abstract for the great cytoskeleton extravaganza!
Reposted by Shashank Shekhar lab
#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
December 5, 2025 at 4:11 PM
#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
Reposted by Shashank Shekhar lab
This alternative view of “condensate” biogenesis is compatible with everything that LLPS claims for itself, including the apparent liquid-like behavior that people a bit ignorant of dynamics find so exciting. I explained this here
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
On the role of phase separation in the biogenesis of membraneless compartments | The EMBO Journal
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
November 29, 2025 at 3:12 PM
This alternative view of “condensate” biogenesis is compatible with everything that LLPS claims for itself, including the apparent liquid-like behavior that people a bit ignorant of dynamics find so exciting. I explained this here
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Reposted by Shashank Shekhar lab
Any protein crystallographer will tell you that almost any concentrated pure protein in isolation in a simple buffer can be made to phase separate in vitro. It’s an artefact.
December 1, 2025 at 8:30 AM
Any protein crystallographer will tell you that almost any concentrated pure protein in isolation in a simple buffer can be made to phase separate in vitro. It’s an artefact.
Reposted by Shashank Shekhar lab
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
So cool! Work from cell bio colleague Dorothy Lerit's lab @lablerit.bsky.social, featured in MBoC!
From MBoC… Dorothy Lerit (Emory University) shows how cells choreograph RNA delivery to their division centers—keeping the process of cell division precise and on time.
🔗 www.molbiolcell.org/doi/full/10....
🔗 www.molbiolcell.org/doi/full/10....
November 15, 2025 at 12:18 AM
So cool! Work from cell bio colleague Dorothy Lerit's lab @lablerit.bsky.social, featured in MBoC!
Reposted by Shashank Shekhar lab
Ten years ago, I saw a paper with some data that has bothered me ever since: B cells in a 0-100 ng/mL gradient of CCL19 are attracted to CCL19, but B cells in 0-500 ng/mL are repelled (see movie, ignoring the big clusters for now!). Why? Here's our model! doi.org/10.1101/2025...
October 30, 2025 at 5:32 PM
Ten years ago, I saw a paper with some data that has bothered me ever since: B cells in a 0-100 ng/mL gradient of CCL19 are attracted to CCL19, but B cells in 0-500 ng/mL are repelled (see movie, ignoring the big clusters for now!). Why? Here's our model! doi.org/10.1101/2025...
Reposted by Shashank Shekhar lab
Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost!
PNAS www.pnas.org/doi/10.1073/...
PNAS www.pnas.org/doi/10.1073/...
November 11, 2025 at 11:01 PM
Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost!
PNAS www.pnas.org/doi/10.1073/...
PNAS www.pnas.org/doi/10.1073/...
Reposted by Shashank Shekhar lab
While this does not excuse his other actions, for me it does illustrate the complexity of some human beings who can be truly dreadful in many ways and, yet, make some surprising and important positive contributions.
40/41
40/41
November 8, 2025 at 1:58 PM
While this does not excuse his other actions, for me it does illustrate the complexity of some human beings who can be truly dreadful in many ways and, yet, make some surprising and important positive contributions.
40/41
40/41
Reposted by Shashank Shekhar lab
Somehow I missed this tentative but important news -- extension of the NIGMS MIRA (R35) mechanism
simpler.grants.gov/opportunity/...
simpler.grants.gov/opportunity/...
Opportunity Listing - Maximizing Investigators' Research Award
Read detailed information about this funding opportunity.
simpler.grants.gov
September 16, 2025 at 9:18 PM
Somehow I missed this tentative but important news -- extension of the NIGMS MIRA (R35) mechanism
simpler.grants.gov/opportunity/...
simpler.grants.gov/opportunity/...
Reposted by Shashank Shekhar lab
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
Computational image analyst (m/f/d)
The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a
jobs.mpi-muenster.mpg.de
September 12, 2025 at 6:17 AM
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
Reposted by Shashank Shekhar lab
How do cells keep their #actin “highways” stable?🚦
Our paper @PLOS Genetics reveals surprising teamwork (and backup plans!) between tropomyosin isoforms in yeast. #imaging #cytoskeleton #celldivision
This work was brilliantly led by @anubhavdhar.bsky.social @bagyasree.bsky.social
t.co/RvUrzad5tL
Our paper @PLOS Genetics reveals surprising teamwork (and backup plans!) between tropomyosin isoforms in yeast. #imaging #cytoskeleton #celldivision
This work was brilliantly led by @anubhavdhar.bsky.social @bagyasree.bsky.social
t.co/RvUrzad5tL
September 9, 2025 at 6:22 PM
How do cells keep their #actin “highways” stable?🚦
Our paper @PLOS Genetics reveals surprising teamwork (and backup plans!) between tropomyosin isoforms in yeast. #imaging #cytoskeleton #celldivision
This work was brilliantly led by @anubhavdhar.bsky.social @bagyasree.bsky.social
t.co/RvUrzad5tL
Our paper @PLOS Genetics reveals surprising teamwork (and backup plans!) between tropomyosin isoforms in yeast. #imaging #cytoskeleton #celldivision
This work was brilliantly led by @anubhavdhar.bsky.social @bagyasree.bsky.social
t.co/RvUrzad5tL
Reposted by Shashank Shekhar lab
Our latest preprint on the role of the Arp2/3 complex in mitotic entry is now available @biorxiv. This work was done by Dhanya Kalathil, a very talented postdoc in my lab. The story started in 2019 when we were investigating the role of branched actin in cytokinesis. 1/
September 6, 2025 at 10:08 PM
Our latest preprint on the role of the Arp2/3 complex in mitotic entry is now available @biorxiv. This work was done by Dhanya Kalathil, a very talented postdoc in my lab. The story started in 2019 when we were investigating the role of branched actin in cytokinesis. 1/
Reposted by Shashank Shekhar lab
Just started our @bcube-tud.bsky.social - organized Engineering Life 2025 #25EngLife conference in #Dresden! Excited to have everybody around!
September 1, 2025 at 8:25 AM
Just started our @bcube-tud.bsky.social - organized Engineering Life 2025 #25EngLife conference in #Dresden! Excited to have everybody around!