Sophie G Martin
@sophiemartinlab.bsky.social
Professor @Biologie_UNIGE @MoCel_Geneva
Loves cells under the microscope!
Loves cells under the microscope!
Reposted by Sophie G Martin
If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X
October 30, 2025 at 11:44 AM
If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X
Reposted by Sophie G Martin
How is #cytokinesis coordinated to ensure successful #CellDivision? Jian-Qiu Wu @sophiemartinlab.bsky.social &co show that the Ync13-Rga7-Rng10 module coordinates selective tethering & fusion of vesicles containing glucan synthases at the division site @plosbiology.org 🧪 plos.io/43zJ35Z
October 28, 2025 at 5:31 PM
How is #cytokinesis coordinated to ensure successful #CellDivision? Jian-Qiu Wu @sophiemartinlab.bsky.social &co show that the Ync13-Rga7-Rng10 module coordinates selective tethering & fusion of vesicles containing glucan synthases at the division site @plosbiology.org 🧪 plos.io/43zJ35Z
Reposted by Sophie G Martin
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
October 7, 2025 at 5:49 PM
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Super happy to see also this story out! 👇
7 years of amazing perseverance from @gaowen.bsky.social, who not only performed experimental evolution showing tradeoff between sexual and asexual reproduction, but also identified all key transcription and genome changes.
www.biorxiv.org/content/10.1...
7 years of amazing perseverance from @gaowen.bsky.social, who not only performed experimental evolution showing tradeoff between sexual and asexual reproduction, but also identified all key transcription and genome changes.
www.biorxiv.org/content/10.1...
Sex or growth? Life must continually balance these strategies. We forced yeast to choose and captured the trade-off in real time. Evolution rewired existing regulators and fixed them through genetic assimilation, creating specialists for sex at the cost of growth.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
September 28, 2025 at 1:24 PM
Super happy to see also this story out! 👇
7 years of amazing perseverance from @gaowen.bsky.social, who not only performed experimental evolution showing tradeoff between sexual and asexual reproduction, but also identified all key transcription and genome changes.
www.biorxiv.org/content/10.1...
7 years of amazing perseverance from @gaowen.bsky.social, who not only performed experimental evolution showing tradeoff between sexual and asexual reproduction, but also identified all key transcription and genome changes.
www.biorxiv.org/content/10.1...
Super excited that this story by @borissieber.bsky.social is now on BioRxiv!
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
September 25, 2025 at 7:48 PM
Super excited that this story by @borissieber.bsky.social is now on BioRxiv!
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
Reposted by Sophie G Martin
Our department of Plant Molecular Biology at the University of Lausanne @unil.bsky.social is recruiting a Tenure-Track Assistant Professor in the field of Plant-Organism Interactions 🌱🐛🦠🍄! Application before November 30, 2025. See the official job ad for more details: tinyurl.com/mtxdcz6p
September 17, 2025 at 8:00 PM
Our department of Plant Molecular Biology at the University of Lausanne @unil.bsky.social is recruiting a Tenure-Track Assistant Professor in the field of Plant-Organism Interactions 🌱🐛🦠🍄! Application before November 30, 2025. See the official job ad for more details: tinyurl.com/mtxdcz6p
Reposted by Sophie G Martin
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
July 7, 2025 at 2:05 PM
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
Reposted by Sophie G Martin
Come and Join our Dpt in Beautiful #Geneva !
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
July 8, 2025 at 4:24 AM
Come and Join our Dpt in Beautiful #Geneva !
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
Reposted by Sophie G Martin
How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 24, 2025 at 7:22 PM
How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sophie G Martin
🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
June 19, 2025 at 8:58 AM
🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Reposted by Sophie G Martin
Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
June 16, 2025 at 4:18 PM
Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
Reposted by Sophie G Martin
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM
wwwfbm.unil.ch
June 10, 2025 at 1:53 PM
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
Beautiful images 🤩
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhavdhar.bsky.social in collaboration with Sudarshan and Deepak Nair. www.biorxiv.org/content/10.1...
May 16, 2025 at 3:47 PM
Beautiful images 🤩
Reposted by Sophie G Martin
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
May 2, 2025 at 8:55 AM
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
The lab is on a roll. 2nd preprint in as many weeks!
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse
Cdc42 is a Rho-family GTPase conserved across eukaryotes, where it plays essential roles in cell polarization. In single-celled yeast systems, Cdc42 is a key driver of symmetry breaking and polarized ...
www.biorxiv.org
May 6, 2025 at 11:20 AM
The lab is on a roll. 2nd preprint in as many weeks!
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
May 2, 2025 at 8:55 AM
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
Reposted by Sophie G Martin
New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work! www.biorxiv.org/content/10.1...
April 23, 2025 at 2:04 PM
New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work! www.biorxiv.org/content/10.1...
Reposted by Sophie G Martin
Important editorial from the EIC @biologists.bsky.social @dev-journal.bsky.social about the current crisis in American science. journals.biologists.com/dev/article/...
Science under siege: protecting scientific progress in turbulent times
As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...
journals.biologists.com
March 13, 2025 at 11:11 PM
Important editorial from the EIC @biologists.bsky.social @dev-journal.bsky.social about the current crisis in American science. journals.biologists.com/dev/article/...
Reposted by Sophie G Martin
In her Essay, Renata Basto highlights the huge budget cuts facing the scientific community in France. In response to the cuts, a group of researchers has formed the ‘Pour une Recherche d'Avenir’ initiative to secure the future of French research.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
The importance of delivering Recherche d'Avenir – research for the future
In recent years, several European countries, including France, have reduced their investment in scientific research, with biomedical research taking a significant hit. The primary casualty is basic re...
journals.biologists.com
February 26, 2025 at 10:42 AM
In her Essay, Renata Basto highlights the huge budget cuts facing the scientific community in France. In response to the cuts, a group of researchers has formed the ‘Pour une Recherche d'Avenir’ initiative to secure the future of French research.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Sophie G Martin
Still hard to believe but Béla Novák died suddenly on Saturday.
We've lost a fantastic colleague, mentor & great friend to many. There was really no-one else like him. Working with him was so much fun & I owe him a lot. All my thoughts are with his family.
www.merton.ox.ac.uk/news/remembe...
We've lost a fantastic colleague, mentor & great friend to many. There was really no-one else like him. Working with him was so much fun & I owe him a lot. All my thoughts are with his family.
www.merton.ox.ac.uk/news/remembe...
Remembering Professor Béla Novák 1956 - 2025
With great sadness, we announce the loss of Professor Béla Novák.
www.merton.ox.ac.uk
February 25, 2025 at 12:26 PM
Still hard to believe but Béla Novák died suddenly on Saturday.
We've lost a fantastic colleague, mentor & great friend to many. There was really no-one else like him. Working with him was so much fun & I owe him a lot. All my thoughts are with his family.
www.merton.ox.ac.uk/news/remembe...
We've lost a fantastic colleague, mentor & great friend to many. There was really no-one else like him. Working with him was so much fun & I owe him a lot. All my thoughts are with his family.
www.merton.ox.ac.uk/news/remembe...
Reposted by Sophie G Martin
❗ Institut Jacques Monod Lectures❗
📅 February, 7
📍 Institut Jacques Monod
Next Friday, the Institut Jacques Monod lectures will welcome
@sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ buff.ly/3Pzjc79
📅 February, 7
📍 Institut Jacques Monod
Next Friday, the Institut Jacques Monod lectures will welcome
@sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ buff.ly/3Pzjc79
February 3, 2025 at 9:22 AM
❗ Institut Jacques Monod Lectures❗
📅 February, 7
📍 Institut Jacques Monod
Next Friday, the Institut Jacques Monod lectures will welcome
@sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ buff.ly/3Pzjc79
📅 February, 7
📍 Institut Jacques Monod
Next Friday, the Institut Jacques Monod lectures will welcome
@sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ buff.ly/3Pzjc79
Looking forward to visiting the Institut Jacques Monod @ijmonod.bsky.social and a few days in Paris!
#SaveTheDate
📅 February, 7
📍 Institut Jacques Monod
The Institut Jacques Monod lectures will welcome @sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ www.ijm.fr/event/instit...
📅 February, 7
📍 Institut Jacques Monod
The Institut Jacques Monod lectures will welcome @sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ www.ijm.fr/event/instit...
January 16, 2025 at 1:33 PM
Looking forward to visiting the Institut Jacques Monod @ijmonod.bsky.social and a few days in Paris!
Reposted by Sophie G Martin
#SaveTheDate
📅 February, 7
📍 Institut Jacques Monod
The Institut Jacques Monod lectures will welcome @sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ www.ijm.fr/event/instit...
📅 February, 7
📍 Institut Jacques Monod
The Institut Jacques Monod lectures will welcome @sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ www.ijm.fr/event/instit...
January 15, 2025 at 3:02 PM
#SaveTheDate
📅 February, 7
📍 Institut Jacques Monod
The Institut Jacques Monod lectures will welcome @sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ www.ijm.fr/event/instit...
📅 February, 7
📍 Institut Jacques Monod
The Institut Jacques Monod lectures will welcome @sophiemartinlab.bsky.social , who will present «Signaling and actin focus architecture for cell-cell fusion».
➡️ www.ijm.fr/event/instit...
Reposted by Sophie G Martin
Nitrogen-starvation of #FissionYeast inactivates growth pathways (incl TORC1) & can trigger sexual reproduction. @sophiemartinlab.bsky.social use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪 @plosbiology.org plos.io/4h3OUVO
January 6, 2025 at 5:03 PM
Nitrogen-starvation of #FissionYeast inactivates growth pathways (incl TORC1) & can trigger sexual reproduction. @sophiemartinlab.bsky.social use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪 @plosbiology.org plos.io/4h3OUVO
Reposted by Sophie G Martin
Nitrogen-starvation of #FissionYeast inactivates growth pathways (incl TORC1) & can trigger sexual reproduction. @sophiemartinlab.bsky.social use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪 @plosbiology.org plos.io/4h3OUVO
January 7, 2025 at 9:35 AM
Nitrogen-starvation of #FissionYeast inactivates growth pathways (incl TORC1) & can trigger sexual reproduction. @sophiemartinlab.bsky.social use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪 @plosbiology.org plos.io/4h3OUVO