See-Yeun Ting 陳詩允
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seeyeunting.bsky.social
See-Yeun Ting 陳詩允
@seeyeunting.bsky.social
PI in the Institute of Molecular Biology at Academia Sinica. Studying polymicrobial interaction in bacterial community. http://www.thetinglab.com
Pinned
Excited to learn that our story on characterizing an interbacterial protease toxin is finally out @plosbiology.org
"An interbacterial cysteine protease toxin inhibits cell growth by targeting type II DNA topoisomerases GyrB and ParE". Led by my wonderful team at Academia Sinica!
Be our IMB colleague! Join us for cool science!

[open faculty position at the institute of molecular biology, academia sinica in taiwan]

www.nature.com/naturecareer...
OPEN FACULTY POSITION, INSTITUTE OF MOLECULAR BIOLOGY, ACADEMIA SINICA, TAIWAN - 128 Academia Road, Section 2, Nankang, Taipei, Taiwan job with Institute of Molecular Biology, Academia Sinica, Taiwan ...
One tenure-track faculty position is open for a qualified individual to establish an active research program at the IMB.
www.nature.com
September 5, 2025 at 10:14 PM
Excited to learn that our story on characterizing an interbacterial protease toxin is finally out @plosbiology.org
"An interbacterial cysteine protease toxin inhibits cell growth by targeting type II DNA topoisomerases GyrB and ParE". Led by my wonderful team at Academia Sinica!
May 27, 2025 at 7:57 PM
Reposted by See-Yeun Ting 陳詩允
Always love a good bacterial warfare study:

"Horizontal gene transfer of molecular weapons can reshape bacterial competition"

by @prokaryota.bsky.social, @jdpal.bsky.social, et al. in @plosbiology.org

journals.plos.org/plosbiology/...
Horizontal gene transfer of molecular weapons can reshape bacterial competition
Bacteria use molecular weapons such as toxins to outcompete rivals, but their horizontal gene transfer can undermine this advantage. This study shows that horizontal gene transfer of toxin plasmids is...
journals.plos.org
May 25, 2025 at 10:07 AM
Reposted by See-Yeun Ting 陳詩允
OUT NOW: Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice

#microsky 🧪

www.nature.com/articles/s41...
Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice - Nature Microbiology
InducTn-seq, a method for inducible mutagenesis followed by transposon insertion site sequencing, enables temporal control of transposition to bypass population bottlenecks and enable the quantificati...
www.nature.com
March 27, 2025 at 4:35 PM
Our Phage infection/T6S story is finally out @embojournal.org! "Surface-mediated bacteriophage defense incurs fitness tradeoffs for interbacterial antagonism" Led by my wonderful team at Academia Sinica!
www.embopress.org/doi/full/10....
March 10, 2025 at 1:43 PM
Reposted by See-Yeun Ting 陳詩允
A҉L҉T҉R҉U҉I҉S҉T҉I҉C҉ ҉Z҉O҉M҉B҉I҉E҉ ҉B҉A҉C҉T҉E҉R҉I҉A҉🦠🧟

Fascinating Nat Comm paper Martin Cann Lab Durham UK

Dead bacteria encode post-mortem protein catabolism via Lon protease—provides nutrients promoting growth of surviving bacteria

No benefit of Lon to live bacteria to account for this

www.nature.com/articles/s41...
February 14, 2025 at 5:52 AM
Reposted by See-Yeun Ting 陳詩允
Check it out! Another novel RNA modification - ADP-ribosylation - that was previously only known on proteins. A cousin to #glycoRNA 👏

www.nature.com/articles/s41...
February 6, 2025 at 7:38 PM
Reposted by See-Yeun Ting 陳詩允
Discovery of a distinct BAM complex in the Bacteroidetes https://www.biorxiv.org/content/10.1101/2025.01.31.636011v1
February 2, 2025 at 3:18 AM
Reposted by See-Yeun Ting 陳詩允
A ubiquitin-like protein controls assembly of a bacterial Type VIIb secretion system https://www.biorxiv.org/content/10.1101/2025.01.24.634720v1
January 25, 2025 at 1:19 AM
Reposted by See-Yeun Ting 陳詩允
Beautiful #symbiosis paper. Symbiosis and horizontal gene transfer promote herbivory in the megadiverse leaf beetles
www.cell.com/current-biol...
Symbiosis and horizontal gene transfer promote herbivory in the megadiverse leaf beetles
Leaf beetles are among the most speciose herbivores on earth. Kirsch et al. show that multiple independent symbiont acquisitions and microbe-to-host horizontal gene transfers shaped the beetles’ reper...
www.cell.com
January 20, 2025 at 7:48 AM
Reposted by See-Yeun Ting 陳詩允
What do bacterial cells do when they run out of nutrients? Although most bacterial studies focus on cells in exponentially growing states, in the wild bacteria likely spend most of their time slowly starving to death. 1/n
www.biorxiv.org/content/10.1...
E. coli prepares for starvation by dramatically remodeling its proteome in the first hours after loss of nutrients
It is widely believed that due to nutrient limitations in natural environments, bacteria spend most of their life in non-growing states. However, very little is known about how bacteria change their p...
www.biorxiv.org
January 15, 2025 at 11:12 AM
Breaking Barriers: Gender Equity in Science, Institute of Molecular Biology, Academia Sinica, Taiwan. Together, stronger!
www.youtube.com/watch?v=c4GE...
Breaking Barriers: Gender Equity in Science at IMB Academia Sinica
YouTube video by Institute of Molecular Biology 中央研究院 分子生物研究所
www.youtube.com
January 9, 2025 at 12:14 PM
Reposted by See-Yeun Ting 陳詩允
OUT NOW - Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection

www.nature.com/articles/s41...
Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection - Nature Microbiology
A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.
www.nature.com
January 8, 2025 at 12:11 PM
Reposted by See-Yeun Ting 陳詩允
New year, new paper! Now published in @nature.com. We identified and characterised diverse immune cell states in plants under pathogen attack. My postdoc work in the Ecker lab at @salkinstitute.bsky.social. A thread (0/n)
#PlantScience
www.nature.com/articles/s41...
January 8, 2025 at 4:27 PM
Reposted by See-Yeun Ting 陳詩允
🚨New review🚨

Evolution and ecology of anti-defence systems in phages and plasmids

Link: www.cell.com/current-biol...
January 7, 2025 at 10:27 AM
Reposted by See-Yeun Ting 陳詩允
Ten species comprise half of the bacteriology literature, leaving most species unstudied https://www.biorxiv.org/content/10.1101/2025.01.04.631297v1
January 5, 2025 at 8:17 AM
Reposted by See-Yeun Ting 陳詩允
Starvation of the bacteria Vibrio atlanticus promotes lightning group-attacks on the dinoflagellate Alexandrium pacificum https://www.biorxiv.org/content/10.1101/2024.12.18.629110v1
January 4, 2025 at 11:18 PM
Reposted by See-Yeun Ting 陳詩允
The bully phage: A Shiga toxin-encoding prophage interferes with the induction of co-hosted prophages https://www.biorxiv.org/content/10.1101/2025.01.01.630987v1
January 2, 2025 at 4:19 PM
Reposted by See-Yeun Ting 陳詩允
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense https://www.biorxiv.org/content/10.1101/2024.12.30.630793v1
December 31, 2024 at 5:18 PM
Reposted by See-Yeun Ting 陳詩允
An Interbacterial Cysteine Protease Toxin Inhibits Cell Growth by Targeting Type II DNA Topoisomerases GyrB and ParE https://www.biorxiv.org/content/10.1101/2024.12.30.630690v1
December 31, 2024 at 8:16 AM