Jeremy Reiter
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reitergroup.bsky.social
Jeremy Reiter
@reitergroup.bsky.social
530 followers 1.1K following 81 posts
Biologist especially interested in cilia, signaling and development!
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Reposted by Jeremy Reiter
barrlab.bsky.social
The once-in-a-lifetime comedic queen Catherine O'Hara had situs inversus

#cilia #ciliopathy

www.usatoday.com/story/entert...
a woman in a long black dress is walking down a foggy street .
ALT: a woman in a long black dress is walking down a foggy street .
media.tenor.com
January 31, 2026 at 6:39 PM
Reposted by Jeremy Reiter
jbwallingford.bsky.social
Cilia alert! Stoked to have the new paper from Juyeon Hong about a new domain at the extreme distal tip of motile cilia! (The EDT, y'all!) It's out now @natcomms.nature.com.
Check it out!
#cilia

www.nature.com/articles/s41...
A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function - Nature Communications
Here they combine in vivo imaging with proteomics to characterize a protein complex comprised of Ccdc78 and Ccdc33 that acts at the extreme distal tip of 9 + 2 motile cilia to control tip architecture...
www.nature.com
January 29, 2026 at 1:23 AM
Reposted by Jeremy Reiter
admirablewomen.bsky.social
Biochemist/molecular biologist Joan Steitz was born #OTD in 1941.

She (& team) figured out how our cells read/use genetic instructions to make proteins. A key person who helped crack the code on RNA—the molecule that acts like a messenger between DNA & and the proteins our bodies need. #WomenInSTEM
Color photograph of Joan Steitz (Joan Argetsinger Steitz), the distinguished American molecular biologist and biochemist renowned for her groundbreaking discoveries in RNA biology, including the identification of small nuclear ribonucleoproteins (snRNPs) essential to RNA splicing. She is pictured in a close-up portrait within a laboratory or research setting, smiling warmly and directly at the camera with an engaging, approachable expression that conveys enthusiasm and expertise. Steitz has gray hair pulled back, striking blue eyes, and is wearing large, elaborate dangling earrings adorned with purple gemstones and metallic accents. She is dressed in a rich purple blouse. The softly blurred background includes scientific elements such as lab benches, equipment, monitors, charts, and partial signage, evoking the environment of her long career at Yale University where she served as Sterling Professor of Molecular Biophysics and Biochemistry. #JoanSteitz #MolecularBiology #WomenInScience #Biochemistry #RNA
January 26, 2026 at 7:08 PM
Reposted by Jeremy Reiter
admirablewomen.bsky.social
Jane Richardson was born #OTD in 1941

+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012

#WomenInSTEM
Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas. Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or “ribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent α-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of β-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustration—a timeless bridge between molecular reality and human imagination.
January 26, 2026 at 12:06 AM
Reposted by Jeremy Reiter
devbiol.bsky.social
#DBfeature

Centriolar defects underlie a primary ciliary dyskinesia phenotype in an adenylate kinase 7 deficient ciliated epithelium

By Jennifer Sheridan, Aline Grata, Julia Dorr, Eve E. Suva, Enzo Bresteau, Linus R. Mitchell, Osama Hassan, Brian Mitchell

tinyurl.com/c88cax5z
AK7 deletion causes an impairment of fluid flow and ciliary function. (A) Representative images of MCCs stained with anti-AK7 (magenta, white) and anti-acetylated tubulin (cyan) antibodies together with phalloidin (green) showing strong ciliary staining in controls (Cas9 alone or gRNA alone) that is missing in AK7 KO cells (Cas9 + gRNAs). Scale is 5 μm.
January 20, 2026 at 3:06 PM
Reposted by Jeremy Reiter
cilialab.bsky.social
Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social 🥰🥰 journals.biologists.com/jcs/pages/ci...
January 16, 2026 at 7:30 PM
Reposted by Jeremy Reiter
konjikusicmia.bsky.social
Excited to have my first senior author publication out in the world! An awesome collab between myself in @reitergroup.bsky.social's lab and the Berbari lab at IU. We found primary cilia are necessary for postnatal pituitary development. 1/n.

www.sciencedirect.com/science/arti...
Primary cilia and BBS4 are required for postnatal pituitary development
Primary cilia orchestrate several signaling pathways, and their disruption results in pleiotropic disorders called ciliopathies. Bardet-Beidl syndrome…
www.sciencedirect.com
January 8, 2026 at 7:18 PM
Reposted by Jeremy Reiter
kawillis.bsky.social
Today is a big day.

After many years of work, I’m excited to finally share a paper describing a novel approach to identifying potential breakthroughs in biomedical research, up to twelve years before the breakthrough itself occurs. 1/15
December 18, 2025 at 8:38 PM
Reposted by Jeremy Reiter
cilialab.bsky.social
Just over a week to our FIRST event for 2️⃣0️⃣2️⃣6️⃣- 13/01/2026 15:00-17:30 GMT. What better way to fire up those neural circuits than dipping into the latest breaking #Cilia and #Centrosome science 🧪? Free and open to everyone- /1
January 5, 2026 at 5:29 PM
reitergroup.bsky.social
Modern biology research is biased towards investigating genes that are widely conserved and present in humans. What about genes that ARE widely conserved but NOT present in humans? Can genes missing from humans tell us something about what makes our biology different from that of other animals? 1/8
December 31, 2025 at 7:29 PM
Reposted by Jeremy Reiter
benoitbruneau.bsky.social
Helping this mood is our latest now out in its final form! @irfankathiriya.bsky.social leading the teams with me. Thanks to the editors and reviewers (incl. @wythelab.bsky.social)for a pleasant and productive journey. More to come when the full issue is out. www.nature.com/articles/s44...
A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects - Nature Cardiovascular Research
Kathiriya et al. identify a cardiac progenitor lineage with expression of Tbx5 and anterior heart field-specific expression of Mef2c that bisects the intraventricular septum during development and sho...
www.nature.com
December 29, 2025 at 4:03 PM
reitergroup.bsky.social
Happy holidays! My mind remains boggled how, kinda like the ghost of Christmas past, scientists who may be long dead and I will never meet IRL can tell me their most cherished thoughts. All I have to do to activate this trans-generational telepathic ability is download and read their old papers. 1/4
December 24, 2025 at 11:57 PM
Reposted by Jeremy Reiter
builab.bsky.social
Tired of drawing cilia or centrioles for slides and papers? I feel you.

Check out CiliaBuilder for ChimeraX → cxtoolshed.rbvi.ucsf.edu/apps/chimera...

Build custom 3D cilia & centriole models (tips + primary cilia included).
December 23, 2025 at 8:02 PM
Reposted by Jeremy Reiter
biologyopen.bsky.social
#WntA is a crucial marker of stripe elements early in development for the Nymphalidae butterfly family. @jasminealqassar.bsky.social & co explore if WntA has maintained its role in stripe elements over 95 million years of evolution in the Hesperiidae family of butterflies. doi.org/10.1242/bio....
Hypotheses of stripe pattern homology between nymphalids and hesperiids. (A) Current summary of the nymphalid ground plan, mainly based on the terminology of Schwanwitsch (Nijhout, 1991; Schwanwitsch, 1924) and including recent updates by Otaki and Mazo-Vargas et al. (Mazo-Vargas et al., 2017; Otaki, 2012; Otaki, 2021; Schwanwitsch, 1956). Discalis elements (D1 and D2); CSS, central symmetry system (cyan); BoSS, border ocelli symmetry system (magenta); Oc, forewing border ocelli; pPf and dPf, proximal and distal parafocal elements; MBS, marginal band system (green). Colored vignettes denote vein intersection landmarks. Magenta square, junction between R and M vein trunks; yellow dot, M1-M2 junction; red star, junction between discal crossvein and M3; blue cross, M3-Cu2 junction; green triangle, Cu1-Cu2 junction. Rectangles feature the name of marker genes. (B) Ventral wing patterns of the nymphalid Prepona eugenes with ground plan annotations proposed by Schwanwitsch, 1956 (left: reproduction of published drawings; right: equivalent annotations as color overlays). (C) Phylogenetic relationship between Papilionoidae families. (D) Ventral wing patterns of the hesperiid P. sidae annotated as in panel A, and highlighting the inferred CSS predicted by Schwanwitsch, 1956 (left panel). According to this author, the CSS marks a grey pattern in forewings, and a dislocated white stripe pattern in hindwings, suggesting uncoupling of pattern and color state in fore/hindwings in skippers. The forewing CSS is markedly dislocated along the Cu1 vein (arrowhead).
December 17, 2025 at 8:09 PM
reitergroup.bsky.social
I don’t always eat cake, but when I do, I prefer it to be ninefold symmetric. Cake credit: Thao Phan.
December 17, 2025 at 9:38 PM
reitergroup.bsky.social
The vestibular system in your inner ear keeps you spatially oriented (problems cause vertigo). Comb jellies have similar statocysts, perhaps the first sensory organ. The cilia build the statocysts by transporting cells to their tips... like little escalators!
www.sciencedirect.com/science/arti...
Lithocytes are transported along the ciliary surface to build the statolith of ctenophores
All organisms capable of locomotion possess equilibrium receptor systems that use the gravitational field as a reference. In aquatic invertebrates, gr…
www.sciencedirect.com
December 17, 2025 at 5:36 PM
Reposted by Jeremy Reiter
jcellsci.bsky.social
Submit your latest research to our upcoming special issue: Cell Biology of the Nucleus. This issue is being coordinated by Abby Buchwalter @abbybuch.bsky.social, working alongside Megan King @luskinglab.bsky.social.
Deadline: 5 January 2026
journals.biologists.com/jcs/pages/nu...
Call for papers for JCS Special Issue Text: Special Issue Cell Biology of the Nucleus Guest Editor: Abby Buchwalter Deadline: 5 January 2026 Image of a cell with a heart-shaped nucleus (Image credit: Hoang Anh Le) Journal of Cell Science logo Call for papers Image credit: Hoang Anh Le At the heart of a cancer cell – An Ewing’s sarcoma cancer cell with a curious heart-shaped nucleus. Imaged using Zeiss880 with Airyscan.
December 10, 2025 at 3:02 PM
Reposted by Jeremy Reiter
jamesbriscoe.bsky.social
Good to see the peer reviewed version of this published

A chemo-optogenetic system for spatiotemporal control of gene expression

We use it to:

- Reconstruct SHH mediated neural tube patterning in vitro

- Measure extracellular half-life of Shh

www.cell.com/developmenta...
Investigating morphogen and patterning dynamics with optogenetic control of morphogen production
Benzinger et al. develop a chemo-optogenetic system for precise spatiotemporal control of morphogen production in vitro. Using light-controlled Sonic hedgehog expression, they recapitulate neural tube...
www.cell.com
December 16, 2025 at 1:45 AM
Reposted by Jeremy Reiter
plosbiology.org
How does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
C2CD3 localizes to a ring structure observed in the lumen of the distal centriole by in situ cryo-electron tomography. Top: Confocal image of an expanded mouse photoreceptor cell immunolabeled for tubulin (magenta) and C2CD3 (green). DC, daughter centriole; BB, basal body; TZ, transition zone; CC, connecting cilium. Scale bar: 500 nm. Middle: In situ cryo-tomogram slices taken along the longitudinal axis of the centriole and connecting cilium. White arrowheads indicate microtubule triplets, black arrowheads indicate microtubule doublets, orange arrowheads mark the luminal ring structure, and yellow highlights the membrane. Scale bar: 50 nm. Bottom: Model of the architecture of the distal region of the human centriole.
December 10, 2025 at 9:10 AM
Reposted by Jeremy Reiter
centriolelab.bsky.social
We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)!

GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging.

Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations.

👉 www.unige.ch/genexm/
December 10, 2025 at 8:43 PM
Reposted by Jeremy Reiter
jbwallingford.bsky.social
Calling all postdocs! Applications are open for Dept. of Molecular Biosciences 3rd Trailblazers Postdoctoral Symposium @utaustin.bsky.social. Come to Austin, meet your peers, showcase your work. Application is easy and all expenses are paid! Spread the word!

tinyurl.com/yw7ffjn9
Microsoft Forms
tinyurl.com
December 10, 2025 at 6:27 PM
reitergroup.bsky.social
Summary data from 2025 NIH and NSF funding: www.nytimes.com/interactive/...
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine
A quiet policy change means the government is making fewer bets on long-term science.
www.nytimes.com
December 2, 2025 at 5:21 PM
Reposted by Jeremy Reiter
wallaceucsf.bsky.social
Cells can form patterns within themselves just like embryos do. How? Connie Yan's new preprint shows how the anterior-posterior cytoskeleton pattern in Stentor is dictated by regionalized scaffolding proteins

www.biorxiv.org/content/10.1...
August 19, 2025 at 8:42 AM
Reposted by Jeremy Reiter
elphegenoralab.bsky.social
Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

now revised and journal accepted at www.science.org/doi/10.1126/...

🧵👇
November 27, 2025 at 9:59 PM
reitergroup.bsky.social
Happy Thanksgiving, all!

First meal of the day: Dutch baby, the best of the pancake phylum.
November 27, 2025 at 5:29 PM