Abstract. Some of the most striking examples of phenotypic variation within species are controlled by supergenes. However, most research on supergenes has

“Powerful” method for studying evolution could help researchers understand how species developed specialized eyes

This blog post and the “Deep Dive” podcast, created by NotebookLM, are based on “Energy‐Consumption‐Induced Anthropogenic Heat Release Intensifies Heatwaves and Wildfire Threats in North America: A…

Fish are so delightfully weird. We study the evolutionary genetics and ecology of freshwater fishes, plus a few more things, at Northern Michigan University

A nonabsorbable, intestinal TGR5-targeted conjugate was designed to improve glycemic control while reducing systemic toxicity in mice and pigs.

Nature - Emerging climate impact on carbon sinks in a consolidated carbon budget

Historical nonequilibrium processes are often considered the main drivers of global biodiversity patterns. We argue that while biodiversity is often out of equilibrium, the concept of equilibrium is still crucial for interpreting macroecological diversity patterns, and current confusion in the literature stems from misunderstandings concerning equilibrium dynamics. We demonstrate how an equilibrium-based framework, such as the ‘Equilibrium Theory of Biodiversity Dynamics’ (ETBD), illuminates diversity patterns in space and time, including the latitudinal diversity gradient, even in the out-of-equilibrium context. This framework has profound implications for understanding diversity dynamics during historical, current, and future climate changes, suggesting that while temperate diversity is probably below its equilibrium level, tropical biodiversity could be above its equilibrium, elevating extinction risk in tropical biomes.

The authors show evidence from a German funding line that a lottery-first approach followed by peer review is accompanied by increased female representation both at the submission stage and among fund...

Protons (H+), commonly measured as pH, represent a fundamental physiological parameter in cellular systems. In plants, cytoplasmic H+ levels are tightly regulated to maintain homeostasis, whereas apoplastic H+ concentrations fluctuate dynamically in response to stress and developmental cues. This review discusses and scrutinizes the roles of apoplastic H+ fluctuations in transmitting stress and developmental cues, focusing on their interactions with established regulatory elements, such as phytohormones, H2O2, and peptide–receptor complexes, as well as other functional proteins, within stress and developmental signaling networks. Recent advances in understanding the mechanisms underlying apoplastic H+ as a pivotal regulator of plant adaptation and development open promising avenues for future research to enhance plant resilience and productivity under diverse environmental challenges.

Using SCN2A haploinsufficiency as a proof-of-concept, upregulation of the existing functional gene copy through CRISPR activation was able to rescue neurological-associated phenotypes in Scn2a haploin...

The identification of organisms in environmental samples using metabarcoding relies on factors such as taxonomic assignment methods, genetic markers, reference databases and confidence thresholds ...

Pan-cistrome of the maize leaf under well-watered and drought conditions profiled by haplotype-specific MOA-seq highlights the relevance of transcription factor binding QTLs for understanding phenotypic diversity in maize.

Epigenetic reprogramming is increasingly recognised as a driver of plant immune memory, yet its molecular basis remains poorly understood. Using a chemically inducible transgene in Arabidopsis, we tra...