Nico Posnien
@posnienlab.bsky.social
genotype-phenotype, evo-devo, genetics, transcriptomics, gene regulatory networks, flies, beetles, spiders.
https://www.posnien-lab.net/
https://www.posnien-lab.net/
Pinned
Nico Posnien
@posnienlab.bsky.social
· Jun 2
ATAC‐seq in Emerging Model Organisms: Challenges and Strategies
Principle of ATAC-seq (left), overview of arthropod species with published ATAC-seq data (middle), summary of experimental design (right).
doi.org
You want to apply #ATACseq in your emerging model organism, but you don't know where to start? Is #ATACseq the best method for my research questions? Search no more! We got you covered with our new review: doi.org/10.1002/jez.... Excellent collaboration with @gevol.bsky.social
Reposted by Nico Posnien
Big news last week, our project within @gevol.bsky.social got funded! 🤩 @nturetz.bsky.social @pechmannm.bsky.social @posnienlab.bsky.social, Niko Prpic-Schäper and myself will look into molecular mechanisms and phenotypic consequences of paralog divergence in insects and chelicerates. Stay tuned!
November 11, 2025 at 9:35 AM
Big news last week, our project within @gevol.bsky.social got funded! 🤩 @nturetz.bsky.social @pechmannm.bsky.social @posnienlab.bsky.social, Niko Prpic-Schäper and myself will look into molecular mechanisms and phenotypic consequences of paralog divergence in insects and chelicerates. Stay tuned!
Reposted by Nico Posnien
#Drosophila rules! Help us spread the word @drosospain.bsky.social @fly-eds.bsky.social @genetics-gsa.bsky.social @sse-evolution.bsky.social @fly-jedi.bsky.social @flybase.bsky.social @alliancegenome.bsky.social
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
October 19, 2025 at 10:10 AM
Reposted by Nico Posnien
To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
DrosEU – European Drosophila Population Genomics Consortium
droseu.net
October 19, 2025 at 9:35 AM
To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
Reposted by Nico Posnien
Reposted by Nico Posnien
Phenotypic divergence among European populations was assayed in 173 isofemale lines, spearheaded by Esra Durmaz Mitchell and Thomas Flatt, we show that populations differed markedly in multivariate trait structure @evolletters.bsky.social @eseb.bsky.social academic.oup.com/evlett/artic... (5/7)
Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster
Abstract. A particularly well-studied evolutionary model is the vinegar fly Drosophila melanogaster, a cosmopolitan insect of ancestral southern-central Af
academic.oup.com
October 19, 2025 at 9:35 AM
Phenotypic divergence among European populations was assayed in 173 isofemale lines, spearheaded by Esra Durmaz Mitchell and Thomas Flatt, we show that populations differed markedly in multivariate trait structure @evolletters.bsky.social @eseb.bsky.social academic.oup.com/evlett/artic... (5/7)
Reposted by Nico Posnien
This community effort includes sampling by high school students part of the #citizenscience project #MelanogasterCTF, a joint project between @gonzalezlabbcn.bsky.social and @lcatmon.bsky.social in collaboration with Sònia Casillas @uab.cat, @droseu.bsky.social and #FECYT melanogaster.eu (4/7)
Melanogaster Catch The Fly
melanogaster.eu
October 19, 2025 at 9:35 AM
This community effort includes sampling by high school students part of the #citizenscience project #MelanogasterCTF, a joint project between @gonzalezlabbcn.bsky.social and @lcatmon.bsky.social in collaboration with Sònia Casillas @uab.cat, @droseu.bsky.social and #FECYT melanogaster.eu (4/7)
Reposted by Nico Posnien
DESTv2 analyses show that the spatial genetic structure of populations is stable over time; identify signatures of adaptation that vary between continents; and provide new evidence for seasonal adaptation @molbioevol.bsky.social @official-smbe.bsky.social : academic.oup.com/mbe/article/... (3/7)
Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource
Abstract. Large-scale genomic resources can place genetic variation into an ecologically informed context. To advance our understanding of the population g
academic.oup.com
October 19, 2025 at 9:35 AM
DESTv2 analyses show that the spatial genetic structure of populations is stable over time; identify signatures of adaptation that vary between continents; and provide new evidence for seasonal adaptation @molbioevol.bsky.social @official-smbe.bsky.social : academic.oup.com/mbe/article/... (3/7)
Reposted by Nico Posnien
An expanded release of the community-generated population genomics resource DEST, spearheaded by Marta Coronado-Zamora @geneticament.bsky.social and Joaquin Nunez @jcbnunez.bsky.social, is now available at dest.bio (2/7)
Home
“Drosophila Evolution in Space and Time” (DEST) - A New Population Genomics Resource.
dest.bio
October 19, 2025 at 9:35 AM
An expanded release of the community-generated population genomics resource DEST, spearheaded by Marta Coronado-Zamora @geneticament.bsky.social and Joaquin Nunez @jcbnunez.bsky.social, is now available at dest.bio (2/7)
Reposted by Nico Posnien
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
October 19, 2025 at 9:35 AM
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
Reposted by Nico Posnien
We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
October 3, 2025 at 4:36 PM
We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
Reposted by Nico Posnien
Here it is! Postdoctoral position to identify the progenitors sensory organs in the regenerating legs of Parhyale
apply here: www.averof-lab.org/pages/tracman
1/3
apply here: www.averof-lab.org/pages/tracman
1/3
We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3
October 3, 2025 at 10:47 AM
Here it is! Postdoctoral position to identify the progenitors sensory organs in the regenerating legs of Parhyale
apply here: www.averof-lab.org/pages/tracman
1/3
apply here: www.averof-lab.org/pages/tracman
1/3
Reposted by Nico Posnien
Exciting news!
The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris.
This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics.
More info: populationgeneticsgroup.org.uk
See you there !
The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris.
This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics.
More info: populationgeneticsgroup.org.uk
See you there !
Population Genetics group 59
populationgeneticsgroup.org.uk
September 29, 2025 at 8:52 AM
Exciting news!
The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris.
This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics.
More info: populationgeneticsgroup.org.uk
See you there !
The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris.
This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics.
More info: populationgeneticsgroup.org.uk
See you there !
Reposted by Nico Posnien
Would be excited to chat with folks looking for a postdoc in AI to develop models for genomic prediction...
A great opportunity for funding coming up soon is the Schmidt AI in Science fellowship, due October 13th! apply.interfolio.com/173322
A great opportunity for funding coming up soon is the Schmidt AI in Science fellowship, due October 13th! apply.interfolio.com/173322
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 19, 2025 at 4:20 PM
Would be excited to chat with folks looking for a postdoc in AI to develop models for genomic prediction...
A great opportunity for funding coming up soon is the Schmidt AI in Science fellowship, due October 13th! apply.interfolio.com/173322
A great opportunity for funding coming up soon is the Schmidt AI in Science fellowship, due October 13th! apply.interfolio.com/173322
Long time no see...But we are back with a real firework 🎆. Join us tomorrow at noon for the first #Goenomix talk of the semester by Cassandra Extavour from Havard University. Talk: "One two three: developmental counting mechanisms in reproductive output and evolution". PM for Zoom details.
September 17, 2025 at 7:48 AM
Long time no see...But we are back with a real firework 🎆. Join us tomorrow at noon for the first #Goenomix talk of the semester by Cassandra Extavour from Havard University. Talk: "One two three: developmental counting mechanisms in reproductive output and evolution". PM for Zoom details.
Reposted by Nico Posnien
I'm a bit late to the party over here. I'll be advertising a BBSRC-funded postdoc position soon. So if anyone wants to solve some outstanding questions in limb development - please get in touch. We have a variety of models and approaches (everything from stem cells to sharks). towerslab.weebly.com
September 9, 2025 at 5:58 PM
I'm a bit late to the party over here. I'll be advertising a BBSRC-funded postdoc position soon. So if anyone wants to solve some outstanding questions in limb development - please get in touch. We have a variety of models and approaches (everything from stem cells to sharks). towerslab.weebly.com
Reposted by Nico Posnien
#DBfeature #Drosophia 🪰
Spatiotemporal control of cell ablation using Ronidazole with Nitroreductase in Drosophila
by Gary Teeters, Christina Cucolo, Sagar Kasar, Melanie Worley, and Sarah Siegrist
tiom33.short.gy/DB520,31-40
Spatiotemporal control of cell ablation using Ronidazole with Nitroreductase in Drosophila
by Gary Teeters, Christina Cucolo, Sagar Kasar, Melanie Worley, and Sarah Siegrist
tiom33.short.gy/DB520,31-40
September 7, 2025 at 8:49 AM
#DBfeature #Drosophia 🪰
Spatiotemporal control of cell ablation using Ronidazole with Nitroreductase in Drosophila
by Gary Teeters, Christina Cucolo, Sagar Kasar, Melanie Worley, and Sarah Siegrist
tiom33.short.gy/DB520,31-40
Spatiotemporal control of cell ablation using Ronidazole with Nitroreductase in Drosophila
by Gary Teeters, Christina Cucolo, Sagar Kasar, Melanie Worley, and Sarah Siegrist
tiom33.short.gy/DB520,31-40
Reposted by Nico Posnien
Molecular evolution of dietary shifts in ladybirds 🐞 expansions of digestive & detoxifying #gene families in the herbivorous ladybirds, & absence of most plant cell wall-degrading enzymes in the ladybirds from the transition to carnivory link.springer.com/article/10.1...
Molecular evolution of dietary shifts in ladybird beetles (Coleoptera: Coccinellidae): from fungivory to carnivory and herbivory - BMC Biology
Background Dietary shifts are major evolutionary steps that shape ecological niches and biodiversity. The beetle family Coccinellidae, commonly known as ladybirds, first transitioned from a fungivorou...
link.springer.com
September 6, 2025 at 4:12 PM
Molecular evolution of dietary shifts in ladybirds 🐞 expansions of digestive & detoxifying #gene families in the herbivorous ladybirds, & absence of most plant cell wall-degrading enzymes in the ladybirds from the transition to carnivory link.springer.com/article/10.1...
Reposted by Nico Posnien
Many thanks to all GEvol members for a truly wonderful annual meeting. It was really great to catch up with you all again.
September 5, 2025 at 2:05 PM
Many thanks to all GEvol members for a truly wonderful annual meeting. It was really great to catch up with you all again.
Reposted by Nico Posnien
Red devil spiders from the Canary Islands have a genome half the size of mainland counterparts - Pisarenco, @jrozasub.bsky.social et al. show how purifying selection against slightly deleterious DNA and TE insertions is the primary mechanism.
🔗 doi.org/10.1093/molbev/msaf206
#evobio #molbio #TEsky
🔗 doi.org/10.1093/molbev/msaf206
#evobio #molbio #TEsky
How Did Evolution Halve Genome Size During an Oceanic Island Colonization?
Abstract. Red devil spiders of the genus Dysdera colonized the Canary Islands and underwent an extraordinary diversification. Notably, their genomes are ne
doi.org
September 5, 2025 at 2:52 PM
Red devil spiders from the Canary Islands have a genome half the size of mainland counterparts - Pisarenco, @jrozasub.bsky.social et al. show how purifying selection against slightly deleterious DNA and TE insertions is the primary mechanism.
🔗 doi.org/10.1093/molbev/msaf206
#evobio #molbio #TEsky
🔗 doi.org/10.1093/molbev/msaf206
#evobio #molbio #TEsky
Reposted by Nico Posnien
🧪
The Vienna BioCenter PhD program in Molecular BioSciences will offer 20+ fully-funded positions in the Autumn Call which is now open. Please share. Further details: www.vbcphd.at
September 5, 2025 at 1:40 PM
🧪
Reposted by Nico Posnien
'Overall, the message from this survey is positive– evolutionary biologists are readily employable outside of academia, generally well-prepared for those jobs, and report high levels of satisfaction in their non-academic careers.'
#Preprint
www.biorxiv.org/content/10.1...
#Preprint
www.biorxiv.org/content/10.1...
Leaving Academia: Insights from Evolutionary Biologists on Their Career Transitions and Job Satisfaction
Many who have obtained PhDs in evolutionary biology will ultimately pursue careers that fall outside a narrow definition of an academic career. At the same time, PhD students and supervisors of PhD st...
www.biorxiv.org
September 5, 2025 at 2:02 AM
'Overall, the message from this survey is positive– evolutionary biologists are readily employable outside of academia, generally well-prepared for those jobs, and report high levels of satisfaction in their non-academic careers.'
#Preprint
www.biorxiv.org/content/10.1...
#Preprint
www.biorxiv.org/content/10.1...
Reposted by Nico Posnien
Size matters—but maybe not how we thought. Most chromosomal inversions are just a few hundred bp. Ignoring these “small players” could mean we’ve misunderstood how genomes evolve -out in TREE authors.elsevier.com/a/1ljL1cZ3X3...
September 5, 2025 at 9:11 AM
Size matters—but maybe not how we thought. Most chromosomal inversions are just a few hundred bp. Ignoring these “small players” could mean we’ve misunderstood how genomes evolve -out in TREE authors.elsevier.com/a/1ljL1cZ3X3...
Nice presentations by our PhD students Chetan and Dugcar at the final meeting of phase 1 of @gevol.bsky.social. Great omics results on #spider #genome duplication. Great collab with @pechmannm.bsky.social, @nturetz.bsky.social, @mcordellier.bsky.social and Niko Pripc-Schäper
September 5, 2025 at 1:14 PM
Nice presentations by our PhD students Chetan and Dugcar at the final meeting of phase 1 of @gevol.bsky.social. Great omics results on #spider #genome duplication. Great collab with @pechmannm.bsky.social, @nturetz.bsky.social, @mcordellier.bsky.social and Niko Pripc-Schäper
Reposted by Nico Posnien
Pls. share widely
Calling all transposon fans & lovers of genetic innovation
MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025
→ Vibrant & friendly community
→ Cutting-edge talks from mechanisms to physiology
→ Plenty of surprises (TEs never stop innovating)
submit abstract by July 29
Calling all transposon fans & lovers of genetic innovation
MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025
→ Vibrant & friendly community
→ Cutting-edge talks from mechanisms to physiology
→ Plenty of surprises (TEs never stop innovating)
submit abstract by July 29
⏰ Abstract deadline for 'The mobile genome' is 29 July!
👉 https://s.embl.org/mge25-01-bl
Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍
⭐🧑🏼🔬 24 talks + 15 flash talks from posters – don't miss out!
#EMBOMobileGenome
👉 https://s.embl.org/mge25-01-bl
Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍
⭐🧑🏼🔬 24 talks + 15 flash talks from posters – don't miss out!
#EMBOMobileGenome
July 16, 2025 at 8:43 AM
Pls. share widely
Calling all transposon fans & lovers of genetic innovation
MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025
→ Vibrant & friendly community
→ Cutting-edge talks from mechanisms to physiology
→ Plenty of surprises (TEs never stop innovating)
submit abstract by July 29
Calling all transposon fans & lovers of genetic innovation
MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025
→ Vibrant & friendly community
→ Cutting-edge talks from mechanisms to physiology
→ Plenty of surprises (TEs never stop innovating)
submit abstract by July 29
Reposted by Nico Posnien
At long last, the version of record of our paper on the #platynereis #connectome
"Whole-body connectome of a segmented annelid larva" is out.
Explore the rich online presentation with all the videos, figures and source data here:
https://doi.org/10.7554/eLife.97964
@eLife
@biology […]
"Whole-body connectome of a segmented annelid larva" is out.
Explore the rich online presentation with all the videos, figures and source data here:
https://doi.org/10.7554/eLife.97964
@eLife
@biology […]
Original post on biologists.social
biologists.social
August 28, 2025 at 12:26 PM
At long last, the version of record of our paper on the #platynereis #connectome
"Whole-body connectome of a segmented annelid larva" is out.
Explore the rich online presentation with all the videos, figures and source data here:
https://doi.org/10.7554/eLife.97964
@eLife
@biology […]
"Whole-body connectome of a segmented annelid larva" is out.
Explore the rich online presentation with all the videos, figures and source data here:
https://doi.org/10.7554/eLife.97964
@eLife
@biology […]