SPP 2349 Gevol
@gevol.bsky.social
Bluesky account of the DFG-funded SPP 2349 "Genomic Basis of Evolutionary Innovations" (coordinator: E. Bornberg-Bauer, University Münster)
http://g-evol.com
http://g-evol.com
Reposted by SPP 2349 Gevol
🧩 Thrilled to share our new paper in @genomebiolevol.bsky.social !
We present a comprehensive review of de novo gene emergence — providing a classification of current detection methods and a roadmap for addressing major challenges in the field of gene birth from non-genic sequences.
We present a comprehensive review of de novo gene emergence — providing a classification of current detection methods and a roadmap for addressing major challenges in the field of gene birth from non-genic sequences.
November 12, 2025 at 3:42 PM
🧩 Thrilled to share our new paper in @genomebiolevol.bsky.social !
We present a comprehensive review of de novo gene emergence — providing a classification of current detection methods and a roadmap for addressing major challenges in the field of gene birth from non-genic sequences.
We present a comprehensive review of de novo gene emergence — providing a classification of current detection methods and a roadmap for addressing major challenges in the field of gene birth from non-genic sequences.
Reposted by SPP 2349 Gevol
PhD position available in evolutionary genomics/bioinformatics (hoehnalab.github.io/job_adverts/...). Topic: analyzing gene expression evolution across several firefly species and linking expression changes to genomic architecture. The position is jointly supervised with @anaevolcatalan.bsky.social
hoehnalab.github.io
November 11, 2025 at 9:00 AM
PhD position available in evolutionary genomics/bioinformatics (hoehnalab.github.io/job_adverts/...). Topic: analyzing gene expression evolution across several firefly species and linking expression changes to genomic architecture. The position is jointly supervised with @anaevolcatalan.bsky.social
Reposted by SPP 2349 Gevol
check out the accompanying paper doi.org/10.1093/gbe/... as well!
Validate User
doi.org
November 12, 2025 at 3:45 PM
check out the accompanying paper doi.org/10.1093/gbe/... as well!
Reposted by SPP 2349 Gevol
🚀We’re excited to share our new paper in Bioinformatics!
We introduce a user-friendly toolkit that implements our novel DeNoFo file-format for standardised annotation of de novo gene detection workflows — enabling reproducible methodology descriptions and easier dataset comparison across studies.
We introduce a user-friendly toolkit that implements our novel DeNoFo file-format for standardised annotation of de novo gene detection workflows — enabling reproducible methodology descriptions and easier dataset comparison across studies.
November 12, 2025 at 12:41 PM
🚀We’re excited to share our new paper in Bioinformatics!
We introduce a user-friendly toolkit that implements our novel DeNoFo file-format for standardised annotation of de novo gene detection workflows — enabling reproducible methodology descriptions and easier dataset comparison across studies.
We introduce a user-friendly toolkit that implements our novel DeNoFo file-format for standardised annotation of de novo gene detection workflows — enabling reproducible methodology descriptions and easier dataset comparison across studies.
🎉We are happy to announce that our wonderful GEvol SPP will be funded by @dfg.de for another 3 years. Included are 17 great projects all over Germany with amazing people. You want to be part of this fantastic community? Soon you can find new PhD/Post-Doc positions here & on our website. Stay tuned🎉
November 10, 2025 at 11:39 AM
🎉We are happy to announce that our wonderful GEvol SPP will be funded by @dfg.de for another 3 years. Included are 17 great projects all over Germany with amazing people. You want to be part of this fantastic community? Soon you can find new PhD/Post-Doc positions here & on our website. Stay tuned🎉
Reposted by SPP 2349 Gevol
The DeNoFo format & toolkit for annotating, assessing and comparing the tools and tresholds used in studies of de novo evolved genes is out now in Bioinformatics! Great effort led by @drdomain.bsky.social and Anna Grandchamp!
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
November 3, 2025 at 7:47 PM
The DeNoFo format & toolkit for annotating, assessing and comparing the tools and tresholds used in studies of de novo evolved genes is out now in Bioinformatics! Great effort led by @drdomain.bsky.social and Anna Grandchamp!
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
📢 Check out our GEvol inspired Special Issue in JEZ-B:
onlinelibrary.wiley.com/toc/15525015... 🚨
onlinelibrary.wiley.com/toc/15525015... 🚨
Genomic Basis of Evolutionary Innovations in Insects: Journal of Experimental Zoology Part B: Molecular and Developmental Evolution: Vol 344, No 7
The Journal of Experimental Zoology – B (JEZ-B): Molecular and Developmental Evolution covers the structure & evolution of animal & non-animal organisms.
onlinelibrary.wiley.com
November 3, 2025 at 7:41 AM
📢 Check out our GEvol inspired Special Issue in JEZ-B:
onlinelibrary.wiley.com/toc/15525015... 🚨
onlinelibrary.wiley.com/toc/15525015... 🚨
Reposted by SPP 2349 Gevol
We have put together a comprehensive eQTL map for D. melanogaster using thousands of genetically diverse flies 🪰🪰🪰🪰🪰 We hope this helps -as similar resources have done in yeast and humans- to understand how genetic variation 🧬 regulates complex traits variation 🪰 via transcriptional regulation ⬆️⬇️
Saturating the eQTL map in Drosophila: Genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations
Pallares et al. collect over a thousand RNA-seq and DNA samples from Drosophila melanogaster
flies to investigate the genetic basis of gene expression variation. They find eQTLs
for 98% of the genes a...
www.cell.com
October 14, 2025 at 12:55 PM
We have put together a comprehensive eQTL map for D. melanogaster using thousands of genetically diverse flies 🪰🪰🪰🪰🪰 We hope this helps -as similar resources have done in yeast and humans- to understand how genetic variation 🧬 regulates complex traits variation 🪰 via transcriptional regulation ⬆️⬇️
Many thanks to all GEvol members for a truly wonderful annual meeting. It was really great to catch up with you all again.
September 5, 2025 at 2:05 PM
Many thanks to all GEvol members for a truly wonderful annual meeting. It was really great to catch up with you all again.
Many thanks to Barbara Feldmeyer, Eckart @eckartstolle.bsky.social and Erich @bornberglab.bsky.social for organising and hosting our GEvol-inspired symposium @eseb2025.bsky.social 👏
August 28, 2025 at 7:19 AM
Many thanks to Barbara Feldmeyer, Eckart @eckartstolle.bsky.social and Erich @bornberglab.bsky.social for organising and hosting our GEvol-inspired symposium @eseb2025.bsky.social 👏
Lots of inspiring talks & posters at our GEvol symposium at #ESEB2025 yesterday!
Thanks to everyone who presented, especially our invited speakers @ahuylmans.bsky.social & @rmwaterhouse.bsky.social. From GEvol, Marie Lebherz, Elisa Israel and Barbara Feldmeyer gave talks about their work. (1/2)
Thanks to everyone who presented, especially our invited speakers @ahuylmans.bsky.social & @rmwaterhouse.bsky.social. From GEvol, Marie Lebherz, Elisa Israel and Barbara Feldmeyer gave talks about their work. (1/2)
August 20, 2025 at 12:32 PM
Lots of inspiring talks & posters at our GEvol symposium at #ESEB2025 yesterday!
Thanks to everyone who presented, especially our invited speakers @ahuylmans.bsky.social & @rmwaterhouse.bsky.social. From GEvol, Marie Lebherz, Elisa Israel and Barbara Feldmeyer gave talks about their work. (1/2)
Thanks to everyone who presented, especially our invited speakers @ahuylmans.bsky.social & @rmwaterhouse.bsky.social. From GEvol, Marie Lebherz, Elisa Israel and Barbara Feldmeyer gave talks about their work. (1/2)
Don't miss our symposium (S29: Genomic Basis of Evolutionary Innovations) at @eseb2025.bsky.social tomorrow starting at 11. Hope to see many of you there!
August 18, 2025 at 1:42 PM
Don't miss our symposium (S29: Genomic Basis of Evolutionary Innovations) at @eseb2025.bsky.social tomorrow starting at 11. Hope to see many of you there!
A night full of fun, science and insects: We invite you to join our “Lange Nacht der Insekten” on Sept. 5th, 6pm until midnight, at LWL Museum of Natural History in Münster. Bring your family and friends and explore an ant farm, watch a science slam and visit the planetarium! Entrance is free.
August 13, 2025 at 11:37 AM
A night full of fun, science and insects: We invite you to join our “Lange Nacht der Insekten” on Sept. 5th, 6pm until midnight, at LWL Museum of Natural History in Münster. Bring your family and friends and explore an ant farm, watch a science slam and visit the planetarium! Entrance is free.
@eseb2025.bsky.social We are looking forward to welcome four GEvol members presenting Tuesday 19.8. in S29 "Genomic Basis of evolutionary innovation": Invited Speaker @ahuylmans.bsky.social, Marie Lebherz @bornberglab.bsky.social, Elisa Israel (Prohaska Lab) and Barbara Feldmeyer @sgn.one. 🌞
July 16, 2025 at 10:48 AM
@eseb2025.bsky.social We are looking forward to welcome four GEvol members presenting Tuesday 19.8. in S29 "Genomic Basis of evolutionary innovation": Invited Speaker @ahuylmans.bsky.social, Marie Lebherz @bornberglab.bsky.social, Elisa Israel (Prohaska Lab) and Barbara Feldmeyer @sgn.one. 🌞
🪰🚨 Check the new GEvol paper by our PhD students Andreas Remmel and Karl Kaether and PIs Peter Stadler und Steffen Lemke about stage-specific Genes at Life Stage Transitions in Flies: doi.org/10.1002/jez....
Recently Evolved, Stage‐Specific Genes Are Enriched at Life‐Stage Transitions in Flies
We discovered that 20%–30% of protein-coding genes in Drosophila melanogaster and Aedes aegypti are only expressed during specific stages of development. Surprisingly, many of these stage-specific ge...
doi.org
July 15, 2025 at 12:26 PM
🪰🚨 Check the new GEvol paper by our PhD students Andreas Remmel and Karl Kaether and PIs Peter Stadler und Steffen Lemke about stage-specific Genes at Life Stage Transitions in Flies: doi.org/10.1002/jez....
💻 The last days we had a really interesting workshop on "NEXT LEVEL SCIENCE USING AI ASSISTANTS!" by www.schillermertens.de. As excited as we are about the many possible applications of AI, it's also kind of scary👻.
HOME – Schiller & Mertens
www.schillermertens.de
July 3, 2025 at 6:46 AM
💻 The last days we had a really interesting workshop on "NEXT LEVEL SCIENCE USING AI ASSISTANTS!" by www.schillermertens.de. As excited as we are about the many possible applications of AI, it's also kind of scary👻.
Reposted by SPP 2349 Gevol
🚨 New preprint alert! 🚨
🔬 Ever wondered how new genes emerge from scratch? Meet DESwoMAN, a fully automated pipeline to detect and analyze newly expressed ORFs (neORFs) from transcriptome data — giving us a window into the earliest stages of de novo gene emergence!
(Thread 🧵👇)
🔬 Ever wondered how new genes emerge from scratch? Meet DESwoMAN, a fully automated pipeline to detect and analyze newly expressed ORFs (neORFs) from transcriptome data — giving us a window into the earliest stages of de novo gene emergence!
(Thread 🧵👇)
June 12, 2025 at 9:50 AM
🚨 New preprint alert! 🚨
🔬 Ever wondered how new genes emerge from scratch? Meet DESwoMAN, a fully automated pipeline to detect and analyze newly expressed ORFs (neORFs) from transcriptome data — giving us a window into the earliest stages of de novo gene emergence!
(Thread 🧵👇)
🔬 Ever wondered how new genes emerge from scratch? Meet DESwoMAN, a fully automated pipeline to detect and analyze newly expressed ORFs (neORFs) from transcriptome data — giving us a window into the earliest stages of de novo gene emergence!
(Thread 🧵👇)
Reposted by SPP 2349 Gevol
You want to apply #ATACseq in your emerging model organism, but you don't know where to start? Is #ATACseq the best method for my research questions? Search no more! We got you covered with our new review: doi.org/10.1002/jez.... Excellent collaboration with @gevol.bsky.social
ATAC‐seq in Emerging Model Organisms: Challenges and Strategies
Principle of ATAC-seq (left), overview of arthropod species with published ATAC-seq data (middle), summary of experimental design (right).
doi.org
June 2, 2025 at 8:24 AM
You want to apply #ATACseq in your emerging model organism, but you don't know where to start? Is #ATACseq the best method for my research questions? Search no more! We got you covered with our new review: doi.org/10.1002/jez.... Excellent collaboration with @gevol.bsky.social
🕷️NEW cool GEvol Paper by our Spider Group: "Gene and Genome Duplication in Spiders" by GEvol student Chetan Munegowda, @pechmannm.bsky.social, Nikola Pripic-Schäper and @nturetz.bsky.social
in JEZ-B.🕸️ doi.org/10.1002/jez....
in JEZ-B.🕸️ doi.org/10.1002/jez....
Gene and Genome Duplication in Spiders
In chelicerates whole genome duplications (WGDs) were identified in distinct groups. While there is evidence that Xiphosurans/horseshoe crabs had three rounds of WGD and arachnopulmonates (e.g. spide...
doi.org
June 2, 2025 at 7:55 AM
🕷️NEW cool GEvol Paper by our Spider Group: "Gene and Genome Duplication in Spiders" by GEvol student Chetan Munegowda, @pechmannm.bsky.social, Nikola Pripic-Schäper and @nturetz.bsky.social
in JEZ-B.🕸️ doi.org/10.1002/jez....
in JEZ-B.🕸️ doi.org/10.1002/jez....
NEW PAPER by GEvol member Jacqueline Heckenhauer and her colleques from @sgn.one about Convergence in the Major Silk Gene in Caddisflies.
doi.org/10.1002/jez....
doi.org/10.1002/jez....
De Novo Whole Genome Assemblies of Unusual Case‐Making Caddisflies (Trichoptera) Highlight Genomic Convergence in the Composition of the Major Silk Gene (h‐fibroin)
The major silk gene, h-fibroin, was annotated in high-quality genomes of two unusual case-making Trichoptera. H-Fibroin of Limnocentropus insolitus shows a similar amino acid composition to other cas...
doi.org
May 20, 2025 at 12:46 PM
NEW PAPER by GEvol member Jacqueline Heckenhauer and her colleques from @sgn.one about Convergence in the Major Silk Gene in Caddisflies.
doi.org/10.1002/jez....
doi.org/10.1002/jez....
Check out the brand new Gevol Paper about epigenetic in the Potato Beetle by our students Zoe from the Kurtz lab (Münster) and Elisa from the Prohaska group (Leipzig). doi.org/10.1002/jez....
Multiomics Reveal Associations Between CpG Methylation, Histone Modifications and Transcription in a Species That has Lost DNMT3, the Colorado Potato Beetle
Despite lacking DNMT3, EM-seq revealed CpG methylation in the Colorado potato beetle. CUT&Tag analysis showed an association of H3K36me3 and H3K27ac with transcription, with H3K36me3 mirroring CpG me....
doi.org
May 13, 2025 at 12:01 PM
Check out the brand new Gevol Paper about epigenetic in the Potato Beetle by our students Zoe from the Kurtz lab (Münster) and Elisa from the Prohaska group (Leipzig). doi.org/10.1002/jez....
📢Last Chance: @eseb2025.bsky.social in Barcelona🏖️-->Abstract submission deadline Mai 5th. Please submit a abstract to our symposium #29 Genomic Basis of evolutionary Innovation eseb2025.com/list-of-symp.... With our invited speaker @rmwaterhouse.bsky.social and @ahuylmans.bsky.social.
April 30, 2025 at 7:52 AM
📢Last Chance: @eseb2025.bsky.social in Barcelona🏖️-->Abstract submission deadline Mai 5th. Please submit a abstract to our symposium #29 Genomic Basis of evolutionary Innovation eseb2025.com/list-of-symp.... With our invited speaker @rmwaterhouse.bsky.social and @ahuylmans.bsky.social.
A new paper from our Gevol tandem projects of @bornberglab.bsky.social and the lab of John Parsch (LMU). Check out "Expression of De Novo Open Reading Frames in Natural Populations of Drosophila melanogaster" bsky.app/profile/born...
New Paper Alert! Together with the Parsch lab, we investigated the expression of neORFs (newly evolved expressed open reading frames, identified in a previous study) in Drosophila populations using publicly available RNA-seq data. (1/2)
doi.org/10.1002/jez....
doi.org/10.1002/jez....
Expression of De Novo Open Reading Frames in Natural Populations of Drosophila melanogaster
We show that newly-evolved, expressed open reading frames (neORFs) identified in a set of inbred Drosophila melanogaster lines are also expressed in multiple tissues and developmental stages of poole...
doi.org
April 22, 2025 at 11:48 AM
A new paper from our Gevol tandem projects of @bornberglab.bsky.social and the lab of John Parsch (LMU). Check out "Expression of De Novo Open Reading Frames in Natural Populations of Drosophila melanogaster" bsky.app/profile/born...
Reposted by SPP 2349 Gevol
📢 ONE WEEK LEFT for abstract submission!
Don’t miss the chance to tell #Barcelona and the field of #EvolutionaryBiology all about your amazing work!
📝 Select from 51 approved symposia to submit your #Abstract: https://eseb2025.com/call-for-abstracts/
Don’t miss the chance to tell #Barcelona and the field of #EvolutionaryBiology all about your amazing work!
📝 Select from 51 approved symposia to submit your #Abstract: https://eseb2025.com/call-for-abstracts/
April 16, 2025 at 7:05 AM
📢 ONE WEEK LEFT for abstract submission!
Don’t miss the chance to tell #Barcelona and the field of #EvolutionaryBiology all about your amazing work!
📝 Select from 51 approved symposia to submit your #Abstract: https://eseb2025.com/call-for-abstracts/
Don’t miss the chance to tell #Barcelona and the field of #EvolutionaryBiology all about your amazing work!
📝 Select from 51 approved symposia to submit your #Abstract: https://eseb2025.com/call-for-abstracts/
Reposted by SPP 2349 Gevol
Annotation of 200 insect genomes. Work driven by @stepbystepsolution.bsky.social and Mario Stanke within @gevol.bsky.social : www.biorxiv.org/content/10.1...
Annotation of 200 Insect Genomes with BRAKER for Consistent Comparisons across Species
The annotation of genomes lags behind their sequencing and assembly. For example, of 5,092 insect species in GenBank, as one of the most widely used databases, only 375 currently have annotated genome...
www.biorxiv.org
April 21, 2025 at 5:37 AM
Annotation of 200 insect genomes. Work driven by @stepbystepsolution.bsky.social and Mario Stanke within @gevol.bsky.social : www.biorxiv.org/content/10.1...