Peter Kirk
@peterakirk.bsky.social
Neuroscientist & Psychologist at the NIH | Anxiety & Emotional Disorders, Naturalistic Neuroimaging, Physiology, Development | Disclaimer: all views/posts are my own.
Pinned
Peter Kirk
@peterakirk.bsky.social
· Oct 20
Extending insights from LeDoux: using movies to study subjective, clinically meaningful experiences in neuroscience
Abstract. Neuroscience research with public health relevance to emotional disorders examines brain–behavior relations. Joe LeDoux’s legacy advances these e
doi.org
Happy to share our latest paper on 'using movies to study subjective, clinically meaningful experiences in neuroscience' 🎞️🧠.
doi.org/10.1093/cerc...
doi.org/10.1093/cerc...
Reposted by Peter Kirk
Data only shows associations. Turning those into claims about mechanism or causation? That requires a Rosetta Stone of prior knowledge + theory. Resting-state fMRI is purely observational; correlation is its currency. From this, plenty of "theoretical toys" about brain function can be built...
Resting-State fMRI and the Risk of Overinterpretation: Noise, Mechanisms, and a Missing Rosetta Stone https://www.biorxiv.org/content/10.1101/2025.09.16.676611v1
September 20, 2025 at 1:13 AM
Data only shows associations. Turning those into claims about mechanism or causation? That requires a Rosetta Stone of prior knowledge + theory. Resting-state fMRI is purely observational; correlation is its currency. From this, plenty of "theoretical toys" about brain function can be built...
Reposted by Peter Kirk
Excited to share this new preprint on the Predictive Modelling of Depression Treatment Response using Individual Symptoms and Latent Factors with @clairegillan.bsky.social fresh up on @medrxivpreprint.bsky.social www.medrxiv.org/content/10.1...
Predictive Modelling of Depression Treatment Response using Individual Symptoms and Latent Factors
Machine learning models have increasingly been used to identify predictors of treatment response in depression, and it is hoped that they may eventually help with clinical decision making. However, th...
www.medrxiv.org
September 19, 2025 at 11:58 AM
Excited to share this new preprint on the Predictive Modelling of Depression Treatment Response using Individual Symptoms and Latent Factors with @clairegillan.bsky.social fresh up on @medrxivpreprint.bsky.social www.medrxiv.org/content/10.1...
Reposted by Peter Kirk
Our latest work is now out in @natmentalhealth.nature.com! We examined the role of the basal forebrain and its influence on intrinsic brain networks in depressive and anxiety disorders.
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders - Nature Mental Health
Using 7T resting-state functional MRI data, the authors investigate the effective connectivity of basal forebrain areas in a transdiagnostic sample of patients with anxiety and depression and healthy ...
www.nature.com
September 9, 2025 at 12:03 AM
Our latest work is now out in @natmentalhealth.nature.com! We examined the role of the basal forebrain and its influence on intrinsic brain networks in depressive and anxiety disorders.
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
Reposted by Peter Kirk
The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.
jobs.rutgers.edu/postings/209...
jobs.rutgers.edu/postings/209...
Human Neuroimaging Faculty Positions in Rutgers Brain Health Institute
The Center for Advanced Human Brain Imaging Research (CAHBIR), a component of the Rutgers Brain Health Institute (BHI) on the Busch campus in Piscataway, NJ, is recruiting for two open rank (Assistant...
jobs.rutgers.edu
September 5, 2025 at 7:58 PM
The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.
jobs.rutgers.edu/postings/209...
jobs.rutgers.edu/postings/209...
Reposted by Peter Kirk
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
September 5, 2025 at 2:59 AM
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
Reposted by Peter Kirk
Excited to share that our work is now published in Imaging Neuroscience! 🧠🥳
We show how aging reshapes the brain’s language and memory networks, revealing striking shifts in hemispheric specialization across the lifespan.
Check it out @imagingneurosci.bsky.social
We show how aging reshapes the brain’s language and memory networks, revealing striking shifts in hemispheric specialization across the lifespan.
Check it out @imagingneurosci.bsky.social
New paper in Imaging Neuroscience by Elise Roger, Gaelle E. Doucet, et al:
When age tips the balance: A dual mechanism affecting hemispheric specialization for language
doi.org/10.1162/IMAG...
When age tips the balance: A dual mechanism affecting hemispheric specialization for language
doi.org/10.1162/IMAG...
July 3, 2025 at 11:46 AM
Excited to share that our work is now published in Imaging Neuroscience! 🧠🥳
We show how aging reshapes the brain’s language and memory networks, revealing striking shifts in hemispheric specialization across the lifespan.
Check it out @imagingneurosci.bsky.social
We show how aging reshapes the brain’s language and memory networks, revealing striking shifts in hemispheric specialization across the lifespan.
Check it out @imagingneurosci.bsky.social
A great week of meetings and presenting in Melbourne, including a visit to @orygen.org.au hosted by @sidchop.bsky.social & Lianne Schmaal. Now off to Brisbane for #OHBM2025. I'll be presenting Tuesday and Wednesday, 9am in the Great Hall both days :)
June 23, 2025 at 2:46 AM
A great week of meetings and presenting in Melbourne, including a visit to @orygen.org.au hosted by @sidchop.bsky.social & Lianne Schmaal. Now off to Brisbane for #OHBM2025. I'll be presenting Tuesday and Wednesday, 9am in the Great Hall both days :)
Social anxiety may be related to physical avoidance of aversive stimuli in an interactive game. Our latest study, led by @purnimaqamar.bsky.social. osf.io/preprints/ps...
May 20, 2025 at 5:01 PM
Social anxiety may be related to physical avoidance of aversive stimuli in an interactive game. Our latest study, led by @purnimaqamar.bsky.social. osf.io/preprints/ps...
Reposted by Peter Kirk
Check our latest work ‘Linking Subjective Experience of Anxiety to Brain Function using Natural Language Processing’. Our analyses link movie-evoked brain activity and subsequent interview recordings in a pediatric sample with and without anxiety disorders (doi.org/10.31234/osf...).
May 2, 2025 at 5:29 PM
Check our latest work ‘Linking Subjective Experience of Anxiety to Brain Function using Natural Language Processing’. Our analyses link movie-evoked brain activity and subsequent interview recordings in a pediatric sample with and without anxiety disorders (doi.org/10.31234/osf...).
Check our latest work ‘Linking Subjective Experience of Anxiety to Brain Function using Natural Language Processing’. Our analyses link movie-evoked brain activity and subsequent interview recordings in a pediatric sample with and without anxiety disorders (doi.org/10.31234/osf...).
May 2, 2025 at 5:29 PM
Check our latest work ‘Linking Subjective Experience of Anxiety to Brain Function using Natural Language Processing’. Our analyses link movie-evoked brain activity and subsequent interview recordings in a pediatric sample with and without anxiety disorders (doi.org/10.31234/osf...).
Reposted by Peter Kirk
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
doi.org
April 12, 2025 at 10:28 AM
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
Reposted by Peter Kirk
"To make a meaningful contribution to #neuroscience, #fMRI must break out of its silo."
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
Until recently, in-vivo brain imaging has largely been absent from… integrative efforts, limiting the opportunities to contribute our discoveries, theories or vision toward a comprehensive view of brain function, writes @avramholmes.bsky.social.
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 8, 2025 at 1:19 PM
"To make a meaningful contribution to #neuroscience, #fMRI must break out of its silo."
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.
Reposted by Peter Kirk
Is interoceptive sensing unified across internal organs? 🫀🫁 Our high-powered psychophysical study (N=241) suggests not. Bayesian evidence indicates interoceptive processes are largely modality-specific—challenging the idea of a unitary interoceptive sense.
🔗 Read here: osf.io/preprints/ps...
🔗 Read here: osf.io/preprints/ps...
March 19, 2025 at 2:31 PM
Is interoceptive sensing unified across internal organs? 🫀🫁 Our high-powered psychophysical study (N=241) suggests not. Bayesian evidence indicates interoceptive processes are largely modality-specific—challenging the idea of a unitary interoceptive sense.
🔗 Read here: osf.io/preprints/ps...
🔗 Read here: osf.io/preprints/ps...
Our report on "The Relations Among Anxiety, Movie-Watching, and In-Scanner Motion" is out now in Human Brain Mapping. In short: even anxiety-evoking movies reduce pediatric in-scanner movement compared to 'rest', highlighting its benefit for developmental neuroimaging. doi.org/10.1002/hbm....
March 5, 2025 at 5:03 PM
Our report on "The Relations Among Anxiety, Movie-Watching, and In-Scanner Motion" is out now in Human Brain Mapping. In short: even anxiety-evoking movies reduce pediatric in-scanner movement compared to 'rest', highlighting its benefit for developmental neuroimaging. doi.org/10.1002/hbm....
Reposted by Peter Kirk
The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Unfortunately, we cannot sponsor visas for this position.
Please rt and reach out if you're interested👀
Unfortunately, we cannot sponsor visas for this position.
Please rt and reach out if you're interested👀
March 3, 2025 at 2:50 PM
The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Unfortunately, we cannot sponsor visas for this position.
Please rt and reach out if you're interested👀
Unfortunately, we cannot sponsor visas for this position.
Please rt and reach out if you're interested👀
Reposted by Peter Kirk
Interested in #MRI and #psychiatry? Our lab is hiring a research assistant (@holmeslab-bhi.bsky.social)! Please RT and share.
@geneticssociety.bsky.social
@ohbmofficial.bsky.social
@sfnjournals.bsky.social
@pgcgenetics.bsky.social
@hitop-system.bsky.social
@blackinneuro.bsky.social
@geneticssociety.bsky.social
@ohbmofficial.bsky.social
@sfnjournals.bsky.social
@pgcgenetics.bsky.social
@hitop-system.bsky.social
@blackinneuro.bsky.social
Holmes Lab – Rutgers Department of Psychiatry
holmeslab.rutgers.edu
February 25, 2025 at 3:28 PM
Interested in #MRI and #psychiatry? Our lab is hiring a research assistant (@holmeslab-bhi.bsky.social)! Please RT and share.
@geneticssociety.bsky.social
@ohbmofficial.bsky.social
@sfnjournals.bsky.social
@pgcgenetics.bsky.social
@hitop-system.bsky.social
@blackinneuro.bsky.social
@geneticssociety.bsky.social
@ohbmofficial.bsky.social
@sfnjournals.bsky.social
@pgcgenetics.bsky.social
@hitop-system.bsky.social
@blackinneuro.bsky.social
Reposted by Peter Kirk
🧠 📌 FINAL CALL FOR POST-DOC IN NEUROIMAGING 🧠 📌
Do you have (or will have soon) a PhD in Psychology, Neuroscience or Neuroimaging?
Are you looking for a post-doc in neuroimaging?
Do you want to join a friendly lab in a fab Psychology department?
Do you wish to live in gorgeous Norwich?
Do you have (or will have soon) a PhD in Psychology, Neuroscience or Neuroimaging?
Are you looking for a post-doc in neuroimaging?
Do you want to join a friendly lab in a fab Psychology department?
Do you wish to live in gorgeous Norwich?
February 4, 2025 at 9:06 PM
🧠 📌 FINAL CALL FOR POST-DOC IN NEUROIMAGING 🧠 📌
Do you have (or will have soon) a PhD in Psychology, Neuroscience or Neuroimaging?
Are you looking for a post-doc in neuroimaging?
Do you want to join a friendly lab in a fab Psychology department?
Do you wish to live in gorgeous Norwich?
Do you have (or will have soon) a PhD in Psychology, Neuroscience or Neuroimaging?
Are you looking for a post-doc in neuroimaging?
Do you want to join a friendly lab in a fab Psychology department?
Do you wish to live in gorgeous Norwich?
Reposted by Peter Kirk
Come join us at the ICN. Were looking for an Associate or Full Professor: www.ucl.ac.uk/work-at-ucl/... (these jobs aren't advertised very often!)
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
January 27, 2025 at 12:21 PM
Come join us at the ICN. Were looking for an Associate or Full Professor: www.ucl.ac.uk/work-at-ucl/... (these jobs aren't advertised very often!)
Reposted by Peter Kirk
Interested in understanding what brain activity during movies means from the perspective of the viewer? Then you absolutely need check out this amazing study by @ravenwallace.bsky.social from THinC Lab out now in @elife.bsky.social
A thread 🧵
elifesciences.org/articles/97731
A thread 🧵
elifesciences.org/articles/97731
Mapping patterns of thought onto brain activity during movie-watching
Decoding brain activity using a novel paradigm unveils distinct neural signatures of subjective experiences during movie-watching.
elifesciences.org
January 24, 2025 at 3:06 PM
Interested in understanding what brain activity during movies means from the perspective of the viewer? Then you absolutely need check out this amazing study by @ravenwallace.bsky.social from THinC Lab out now in @elife.bsky.social
A thread 🧵
elifesciences.org/articles/97731
A thread 🧵
elifesciences.org/articles/97731
Reposted by Peter Kirk
I am looking for a post-doc on neuroimaging analysis. Come & join my team at UEA (Norwich, UK). The post is for 32 months starting from April. Norwich is a wonderful & affordable city.
➡Apply: vacancies.uea.ac.uk/vacancies/13...
⏰Deadline: 13 February 2025
Questions: s.rossit@uea.ac.uk
➡Apply: vacancies.uea.ac.uk/vacancies/13...
⏰Deadline: 13 February 2025
Questions: s.rossit@uea.ac.uk
a black and white image of a person 's brain with the letters p and s visible
ALT: a black and white image of a person 's brain with the letters p and s visible
media.tenor.com
January 13, 2025 at 1:37 PM
I am looking for a post-doc on neuroimaging analysis. Come & join my team at UEA (Norwich, UK). The post is for 32 months starting from April. Norwich is a wonderful & affordable city.
➡Apply: vacancies.uea.ac.uk/vacancies/13...
⏰Deadline: 13 February 2025
Questions: s.rossit@uea.ac.uk
➡Apply: vacancies.uea.ac.uk/vacancies/13...
⏰Deadline: 13 February 2025
Questions: s.rossit@uea.ac.uk
Reposted by Peter Kirk
Great work by @halleeshearer.bsky.social in her first first-author paper. With 🎀 shiny app 🎀 to explore how FC reliability fares ACROSS DIFFERENT movies versus rest, region-by-region. Thanks @sneuroble.bsky.social @tingsterx.bsky.social @ninetlab.bsky.social for 👍 collab.
doi.org/10.1162/imag...
doi.org/10.1162/imag...
January 3, 2025 at 5:39 PM
Great work by @halleeshearer.bsky.social in her first first-author paper. With 🎀 shiny app 🎀 to explore how FC reliability fares ACROSS DIFFERENT movies versus rest, region-by-region. Thanks @sneuroble.bsky.social @tingsterx.bsky.social @ninetlab.bsky.social for 👍 collab.
doi.org/10.1162/imag...
doi.org/10.1162/imag...
Back in London for my birthday and celebrating with Chole Bhatura at The Tamil Prince 😋
December 28, 2024 at 2:13 PM
Back in London for my birthday and celebrating with Chole Bhatura at The Tamil Prince 😋
Reposted by Peter Kirk
I thought this was the conclusion of the original BWAS paper? Either way it's both imaging pipelines (specifically driving features from population average atlases) and noisy target phenotypes
The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes
Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
How measurement noise limits the accuracy of brain-behaviour predictions - Nature Communications
Our ability to identify associations between behaviour and brain imaging is important for uncovering markers of cognition and disease. Here, the authors illustrate the importance of the reliability of...
www.nature.com
December 14, 2024 at 5:41 PM
I thought this was the conclusion of the original BWAS paper? Either way it's both imaging pipelines (specifically driving features from population average atlases) and noisy target phenotypes
Reposted by Peter Kirk
Happy to share our latest paper on 'using movies to study subjective, clinically meaningful experiences in neuroscience' 🎞️🧠.
doi.org/10.1093/cerc...
doi.org/10.1093/cerc...
Extending insights from LeDoux: using movies to study subjective, clinically meaningful experiences in neuroscience
Abstract. Neuroscience research with public health relevance to emotional disorders examines brain–behavior relations. Joe LeDoux’s legacy advances these e
doi.org
October 20, 2024 at 3:10 PM
Happy to share our latest paper on 'using movies to study subjective, clinically meaningful experiences in neuroscience' 🎞️🧠.
doi.org/10.1093/cerc...
doi.org/10.1093/cerc...