Simon Eickhoff
@sbe.bsky.social
News & Views on Brain mapping | Machine-Learning | Translational Neuroscience. And triathlon
Director INM-7 FZ Jülich; Professor for Systems Neuroscience HHU Düsseldorf
Director INM-7 FZ Jülich; Professor for Systems Neuroscience HHU Düsseldorf
Reposted by Simon Eickhoff
✨ SHINY NEW PAPER ✨
Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease.
@sbe.bsky.social
www.sciencedirect.com/science/article/pii/S0197458025001034
Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease.
@sbe.bsky.social
www.sciencedirect.com/science/article/pii/S0197458025001034
How is self-reported sleep-disordered breathing linked with biomarkers of Alzheimer’s disease?
Sleep-disordered breathing (SDB) is prevalent in Alzheimer’s disease (AD). Here, we assessed how self-reported SDB is linked with AD biomarkers, inclu…
www.sciencedirect.com
October 7, 2025 at 12:55 AM
✨ SHINY NEW PAPER ✨
Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease.
@sbe.bsky.social
www.sciencedirect.com/science/article/pii/S0197458025001034
Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease.
@sbe.bsky.social
www.sciencedirect.com/science/article/pii/S0197458025001034
Reposted by Simon Eickhoff
Excited to see this work published in @natcomms.nature.com! 🧠📊 In-vivo evidence of E/I alterations underlying functional changes in individuals with autism in the large ABIDE1 dataset AND replication in the independent ABIDE2 dataset.
September 17, 2025 at 12:28 PM
Excited to see this work published in @natcomms.nature.com! 🧠📊 In-vivo evidence of E/I alterations underlying functional changes in individuals with autism in the large ABIDE1 dataset AND replication in the independent ABIDE2 dataset.
Reposted by Simon Eickhoff
New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
September 7, 2025 at 2:59 PM
New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Simon Eickhoff
The end of a PhD journey 🎓 What a ride - full of lovely people, exciting science, coding tunnels, coffee-brainstorms & amazing conferences! Whole-hearted thank you to all who shared the journey & celebrated with me - especially @sofievalk.bsky.social, @sbe.bsky.social &@mps-cognition.bsky.social 💐🥳❤️
August 25, 2025 at 7:23 PM
The end of a PhD journey 🎓 What a ride - full of lovely people, exciting science, coding tunnels, coffee-brainstorms & amazing conferences! Whole-hearted thank you to all who shared the journey & celebrated with me - especially @sofievalk.bsky.social, @sbe.bsky.social &@mps-cognition.bsky.social 💐🥳❤️
Reposted by Simon Eickhoff
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
Reposted by Simon Eickhoff
Amelie Rauland (all star via IRTG student w/ @sbe.bsky.social ) will be presenting "Benchmarking Reconstruction Methods for Bundle Segmentation in Single-Shell dMRI" on Friday and Saturday, Poster #1283
June 25, 2025 at 7:24 AM
Amelie Rauland (all star via IRTG student w/ @sbe.bsky.social ) will be presenting "Benchmarking Reconstruction Methods for Bundle Segmentation in Single-Shell dMRI" on Friday and Saturday, Poster #1283
Reposted by Simon Eickhoff
#ABCD-J #Studienhighlights: Eine kürzlich erschienene Studie zeigt mittels #JTrack Social Unterschiede in Kommunikationsmustern zwischen neurotypischen Erwachsenen und Erwachsenen mit #Autismus-Spektrum-Störung auf. Neugierig geworden? Das ganze Highlight gibt es hier: www.abcd-j.de/de/showcases...
June 6, 2025 at 1:09 PM
#ABCD-J #Studienhighlights: Eine kürzlich erschienene Studie zeigt mittels #JTrack Social Unterschiede in Kommunikationsmustern zwischen neurotypischen Erwachsenen und Erwachsenen mit #Autismus-Spektrum-Störung auf. Neugierig geworden? Das ganze Highlight gibt es hier: www.abcd-j.de/de/showcases...
Reposted by Simon Eickhoff
🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling
Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.
www.science.org
June 5, 2025 at 7:53 AM
🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
Reposted by Simon Eickhoff
⭐ new paper
Maturation of cortical excitation-inhibition (EI) in adolescence
now in Science Advances 💥
A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling
by hiball superheroes 🦸♂️🦸♀️🦸♂️
@amnsbr.bsky.social @sofievalk.bsky.social @sbe.bsky.social
Maturation of cortical excitation-inhibition (EI) in adolescence
now in Science Advances 💥
A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling
by hiball superheroes 🦸♂️🦸♀️🦸♂️
@amnsbr.bsky.social @sofievalk.bsky.social @sbe.bsky.social
🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling
Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.
www.science.org
June 5, 2025 at 12:48 PM
⭐ new paper
Maturation of cortical excitation-inhibition (EI) in adolescence
now in Science Advances 💥
A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling
by hiball superheroes 🦸♂️🦸♀️🦸♂️
@amnsbr.bsky.social @sofievalk.bsky.social @sbe.bsky.social
Maturation of cortical excitation-inhibition (EI) in adolescence
now in Science Advances 💥
A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling
by hiball superheroes 🦸♂️🦸♀️🦸♂️
@amnsbr.bsky.social @sofievalk.bsky.social @sbe.bsky.social
Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
April 24, 2025 at 8:42 PM
Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
Reposted by Simon Eickhoff
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
www.nature.com
March 26, 2025 at 1:54 AM
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
Reposted by Simon Eickhoff
Always thought we should use connectivity blueprints to investigate differences between human, chimpanzee, and macaque brains? www.jneurosci.org/content/earl... For Katherine Bryant’s latest masterpiece.
Connectivity profile and function of uniquely human cortical areas
Determining the brain specializations unique to humans requires directly comparative anatomical information from other primates, especially our closest relatives. Human ( Homo sapiens ) (m/f), chimpan...
www.jneurosci.org
March 18, 2025 at 7:14 AM
Always thought we should use connectivity blueprints to investigate differences between human, chimpanzee, and macaque brains? www.jneurosci.org/content/earl... For Katherine Bryant’s latest masterpiece.
NOW, Join if you're interessted
Topic: DGKN Hackroom 2025 — Tool Talks
Time: Mar 14, 2025 10:30 - 12h
fz-juelich-de.zoom.us/j/6792251876...
Data Management: 10:30 – 11:00
Datalad: GPDR conform collaboration
Jtrack: remote wearable assessment
Topic: DGKN Hackroom 2025 — Tool Talks
Time: Mar 14, 2025 10:30 - 12h
fz-juelich-de.zoom.us/j/6792251876...
Data Management: 10:30 – 11:00
Datalad: GPDR conform collaboration
Jtrack: remote wearable assessment
Join our Cloud HD Video Meeting
Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom ...
fz-juelich-de.zoom.us
March 14, 2025 at 9:28 AM
NOW, Join if you're interessted
Topic: DGKN Hackroom 2025 — Tool Talks
Time: Mar 14, 2025 10:30 - 12h
fz-juelich-de.zoom.us/j/6792251876...
Data Management: 10:30 – 11:00
Datalad: GPDR conform collaboration
Jtrack: remote wearable assessment
Topic: DGKN Hackroom 2025 — Tool Talks
Time: Mar 14, 2025 10:30 - 12h
fz-juelich-de.zoom.us/j/6792251876...
Data Management: 10:30 – 11:00
Datalad: GPDR conform collaboration
Jtrack: remote wearable assessment
Reposted by Simon Eickhoff
Now out in NPJ Digital Medicine our manuscript on real-world evidence for altered communication preferences in autism: nature.com/articles/s41...
@sbe.bsky.social
@leoschilbach.bsky.social
@sbe.bsky.social
@leoschilbach.bsky.social
Real world evidence for altered communication patterns in individuals with autism spectrum disorder - npj Digital Medicine
npj Digital Medicine - Real world evidence for altered communication patterns in individuals with autism spectrum disorder
nature.com
March 12, 2025 at 11:29 AM
Now out in NPJ Digital Medicine our manuscript on real-world evidence for altered communication preferences in autism: nature.com/articles/s41...
@sbe.bsky.social
@leoschilbach.bsky.social
@sbe.bsky.social
@leoschilbach.bsky.social
Reposted by Simon Eickhoff
A new #Neurosalience episode is out! 🧠
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
Neurosalience #S5E10 with Simon Eickhoff - From Big Data to Biomarkers
YouTube video by Organization for Human Brain Mapping
youtu.be
March 6, 2025 at 11:50 AM
A new #Neurosalience episode is out! 🧠
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
Reposted by Simon Eickhoff
Dazu integrieren wir – das Institut für Neurowissenschaften und Medizin: Gehirn und Verhalten (INM-7) @fz-juelich.de, und unsere klinischen Partner an den Unikliniken Aachen, Bonn, Köln, und Düsseldorf – verschiedene technische Lösungen zu einer digitalen Plattform und vernetzen uns.
Hallo Bluesky! Zeit für unsere #Vorstellung. Hier postet das #ABCD-J Projekt. Wir sind eine vom Land NRW geförderte Initiative für die Verbesserung von klinischer Forschung mittels #Biomarkern und #mobileHealth.
March 4, 2025 at 4:46 PM
Dazu integrieren wir – das Institut für Neurowissenschaften und Medizin: Gehirn und Verhalten (INM-7) @fz-juelich.de, und unsere klinischen Partner an den Unikliniken Aachen, Bonn, Köln, und Düsseldorf – verschiedene technische Lösungen zu einer digitalen Plattform und vernetzen uns.
Reposted by Simon Eickhoff
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
January 24, 2025 at 12:02 AM
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes
Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
How measurement noise limits the accuracy of brain-behaviour predictions - Nature Communications
Our ability to identify associations between behaviour and brain imaging is important for uncovering markers of cognition and disease. Here, the authors illustrate the importance of the reliability of...
www.nature.com
December 13, 2024 at 11:24 PM
The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes
Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
This is what happens if preprints are treated as „scientific literature“
Don’t get me wrong, I am all for preprinting. But unfortunately, it is often ignored that anybody can preprint anything
Don’t get me wrong, I am all for preprinting. But unfortunately, it is often ignored that anybody can preprint anything
Letter sent in to the Editor of the Guardian on brain microbiome nonsense.
December 3, 2024 at 11:10 AM
This is what happens if preprints are treated as „scientific literature“
Don’t get me wrong, I am all for preprinting. But unfortunately, it is often ignored that anybody can preprint anything
Don’t get me wrong, I am all for preprinting. But unfortunately, it is often ignored that anybody can preprint anything
Reposted by Simon Eickhoff
We created a #neuroinformagical (obvs) starter pack! Let us know who else to add!
#openscience #datasharing #neuroskyence 🧪
go.bsky.app/LRqnaMP
#openscience #datasharing #neuroskyence 🧪
go.bsky.app/LRqnaMP
November 19, 2024 at 8:44 PM
We created a #neuroinformagical (obvs) starter pack! Let us know who else to add!
#openscience #datasharing #neuroskyence 🧪
go.bsky.app/LRqnaMP
#openscience #datasharing #neuroskyence 🧪
go.bsky.app/LRqnaMP
Reposted by Simon Eickhoff
woo hoo - fantastic new work from @wanb.bsky.social @sofievalk.bsky.social @sbe.bsky.social & many more on microstructural asymmetry now out in Nature Comms ⤵️
Thrilled to share my latest work "Microstructural asymmetry in the human cortex" now out in NatComms. www.nature.com/articles/s41...
This work used cytoarchitecture (BigBrain), T1w/T2w, qT1, and MT measures to bring the cortical asymmetry from macrostructure to microstructure.
This work used cytoarchitecture (BigBrain), T1w/T2w, qT1, and MT measures to bring the cortical asymmetry from macrostructure to microstructure.
Microstructural asymmetry in the human cortex - Nature Communications
The human cortex displays an anterior-to-posterior asymmetry, identified via both post-mortem and in vivo microstructural measurements. Microstructural asymmetry is heritable, varies across cortical l...
www.nature.com
November 25, 2024 at 1:34 PM
woo hoo - fantastic new work from @wanb.bsky.social @sofievalk.bsky.social @sbe.bsky.social & many more on microstructural asymmetry now out in Nature Comms ⤵️
Looked into BlueSky a while ago… really empty at that time
X becoming useless for interesting reads and discussions on science send me in a social-media hiatus
Back now and excited about things to come
X becoming useless for interesting reads and discussions on science send me in a social-media hiatus
Back now and excited about things to come
November 25, 2024 at 7:52 AM
Looked into BlueSky a while ago… really empty at that time
X becoming useless for interesting reads and discussions on science send me in a social-media hiatus
Back now and excited about things to come
X becoming useless for interesting reads and discussions on science send me in a social-media hiatus
Back now and excited about things to come
Reposted by Simon Eickhoff
Useful reminders from @sbe.bsky.social about #neuroimaging analysis #reproducibility at #OHBM2024:
- Different atlases lead to different connectivity matrices.
- The target *massively* matters.
- ML algorithms just *love* shortcuts.
- Different atlases lead to different connectivity matrices.
- The target *massively* matters.
- ML algorithms just *love* shortcuts.
June 27, 2024 at 1:36 AM
Useful reminders from @sbe.bsky.social about #neuroimaging analysis #reproducibility at #OHBM2024:
- Different atlases lead to different connectivity matrices.
- The target *massively* matters.
- ML algorithms just *love* shortcuts.
- Different atlases lead to different connectivity matrices.
- The target *massively* matters.
- ML algorithms just *love* shortcuts.