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wanb.bsky.social
Bin Wan
@wanb.bsky.social
150 followers 300 following 23 posts
Computational Neurogenetics
PostDoc @ Geneva Psychiatry
PhD @mpicbs.bsky.social
Personal web: https://wanb-psych.netlify.app/
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wanb.bsky.social
Bin Wan @wanb.bsky.social · Mar 5
Happy to share my last PhD work "Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients". We used UKB, HCP, and QTAB to analyze the genetics of functional gradients. The results are so good, consistent, and inspiring! (1/3)
Reposted by Bin Wan
gradientsworkshop.bsky.social
It's a wrap! BIG thanks to all speakers, chairs, attendees, and our organizing committee - particularly our superstar local organizers Johan and Saurabh - for making our gradient dreams come true for the sixth year in a row ⭐ 🌈 🧠 🚀
June 23, 2025 at 9:28 AM
Reposted by Bin Wan
ohbmtrainees.bsky.social
🎉🎉#OHBM2025 is just around the corner! Remember to visit the SP-SIG stall next to the registration desk and add stickers to your badge describing your research interests!
June 22, 2025 at 4:29 AM
wanb.bsky.social
I finally defended my thesis! Thanks all! I started my PhD during covid! I am really grateful that my supervisor @sofievalk.bsky.social picked me to be her first PhD student when I was naive to neuroimage. I have been so lucky to stay in this happy and respectful academic environment so far!
June 20, 2025 at 8:56 AM
Reposted by Bin Wan
natmethods.nature.com
An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.

www.nature.com/articles/s41...
Benchmarking methods for mapping functional connectivity in the brain - Nature Methods
In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...
www.nature.com
June 6, 2025 at 3:51 PM
Reposted by Bin Wan
amnsbr.bsky.social
🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling
Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.
www.science.org
June 5, 2025 at 7:53 AM
Reposted by Bin Wan
apertureohbm.bsky.social
Merchant et al. perform a meta-analytic investigation of neurocognitive systems involved in real-time social interaction doi.org/10.52294/001...

@fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social
June 2, 2025 at 2:27 PM
Reposted by Bin Wan
maciekszul.bsky.social
🚨🚨🚨PREPRINT ALERT🚨🚨🚨
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!
Overview of the simulation strategy and analysis. a) Pial and white matter boundaries surfaces are extracted from anatomical MRI volumes. b) Intermediate equidistant surfaces are generated between the pial and white matter surfaces (labeled as superficial (S) and deep (D) respectively). c) Surfaces are downsampled together, maintaining vertex correspondence across layers. Dipole orientations are constrained using vectors linking corresponding vertices (link vectors). d) The thickness of cortical laminae varies across the cortical depth (70–72), which is evenly sampled by the equidistant source surface layers. e) Each colored line represents the model evidence (relative to the worst model, ΔF) over source layer models, for a signal simulated at a particular layer (the simulated layer is indicated by the line color). The source layer model with the maximal ΔF is indicated by “˄”. f) Result matrix summarizing ΔF across simulated source locations, with peak relative model evidence marked with “˄”. g) Error is calculated from the result matrix as the absolute distance in mm or layers from the simulated source (*) to the peak ΔF (˄). h) Bias is calculated as the relative position of a peak ΔF(˄) to a simulated source (*) in layers or mm.
June 2, 2025 at 11:55 AM
Reposted by Bin Wan
anniegbryant.bsky.social
🎨🧑‍🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊

anniegbryant.github.io/subcortex_vi...
May 4, 2025 at 10:13 AM
wanb.bsky.social
See our GWAS of grapical topology🤟
vw1234.bsky.social Varun Warrier @vw1234.bsky.social · Apr 29
Pleased to share new work from our group, led by PhD student Edward He. Edward joined the group as a summer student interested in the genetics of resting state functional connectivity, measured using graph networks.

www.medrxiv.org/content/10.1...
www.medrxiv.org
April 29, 2025 at 1:01 PM
Reposted by Bin Wan
enigmabrains.bsky.social
As always, it was great fun to connect with our ENIGMA Consortium community last night at #SOBP2025 in Toronto - thanks to all who joined us! Cheers to science and the next SOBP conference🍻🧠
April 25, 2025 at 2:45 PM
Reposted by Bin Wan
borismontreal.bsky.social
in press @natcomms.nature.com 🌟

"Multimodal gradients unify local and global cortical organization"

7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration

led by superstar Yezhou Wang & a terrific team of friends & colleagues

▶️ doi.org/10.1038/s414...
April 25, 2025 at 12:58 PM
Reposted by Bin Wan
donnagift.bsky.social
Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲

www.nature.com/articles/s41...

osf.io/mhq3f/

@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
Multimodal precision MRI of the individual human brain at ultra-high fields - Scientific Data
Scientific Data - Multimodal precision MRI of the individual human brain at ultra-high fields
www.nature.com
March 30, 2025 at 1:38 PM
wanb.bsky.social
Happy to share my last PhD work "Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients". We used UKB, HCP, and QTAB to analyze the genetics of functional gradients. The results are so good, consistent, and inspiring! (1/3)
March 5, 2025 at 10:21 AM
Reposted by Bin Wan
commsbio.nature.com
🧠 The GINNA brain atlas offers a comprehensive framework for exploring the functional significance of 33 resting-state networks & their relationship to human cognition.
@imn-bordeaux.bsky.social @achetyl.bsky.social

www.nature.com/articles/s42...
GINNA, a 33 resting-state networks atlas with meta-analytic decoding-based cognitive characterization - Communications Biology
The GINNA brain atlas offers a comprehensive framework for exploring the functional significance of 33 resting-state networks and their relationship to human cognition, using task-based meta-analytic ...
www.nature.com
February 18, 2025 at 7:08 PM
Reposted by Bin Wan
johnalexandra.bsky.social
For all the thalamus lovers❤️‍🔥 : Excited to share that our Paper is out now✨Huge thanks to @sofievalk.bsky.social and all collaborators @meikehettwer.bsky.social, @wanb.bsky.social, @amnsbr.bsky.social, @jroyer.bsky.social, @borismontreal.bsky.social, @linaschaare.bsky.social, Seyma Bayrak
February 7, 2025 at 12:38 PM
Reposted by Bin Wan
jchrispang.bsky.social
For my first-ever bluesky post, I'm really excited to share our new preprint "Geometric influences on the regional organization of the mammalian brain" with @alexfornito.bsky.social and a superstar 17-person team! (1/n)

www.biorxiv.org/content/10.1...
Geometric influences on the regional organization of the mammalian brain
The mammalian brain is comprised of anatomically and functionally distinct regions. Substantial work over the past century has pursued the generation of ever-more accurate maps of regional boundaries,...
www.biorxiv.org
February 3, 2025 at 12:45 AM
Reposted by Bin Wan
borismontreal.bsky.social
Out in @natureneuro.bsky.social today 🥂

Cytoarchitecture, wiring and signal flow of the human default mode network

Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations

Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏
The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow - Nature Neuroscience
The default mode network (DMN) is implicated in cognition and behavior. Here, the authors show that the DMN is cytoarchitecturally heterogeneous, it contains regions receptive to input from the sensory cortex and a core relatively insulated from environmental input, and it uniquely balances its output across sensory hierarchies.
www.nature.com
January 28, 2025 at 2:24 PM
Reposted by Bin Wan
drbreaky.bsky.social
Brains minimize energy consumption while maximizing computation. In humans, this trade-off is reconciled towards complex behaviors & hence relatively high energy use

Review & synthesis with @sharnajamadar.bsky.social @annabhlr.bsky.social & Hamish Deery

tinyurl.com/47c9n65w
osf.io/preprints/os...
January 20, 2025 at 5:58 AM
Reposted by Bin Wan
borismontreal.bsky.social
🍾 Now in press @elife.bsky.social

Multimodal correlates of childhood psychopathology

co-led by @jroyer.bsky.social , Valeria Kebets, @bttyeo.bsky.social & our many fantastic co-authors

🙏 based on the ABCD dataset

👉 elifesciences.org/articles/87992
December 3, 2024 at 8:29 PM
Reposted by Bin Wan
ohbmofficial.bsky.social
🚨 14 DAY REMINDER! 🚨
Only 14 days left to submit your content for #OHBM2025 in Brisbane, Australia! 🗒️ The deadline is December 17, 2024, at 11:59 PM EST. Don’t miss this chance to share your research—follow the link in comments to submit! #Neuroscience #CallforContent
December 3, 2024 at 12:00 PM
Reposted by Bin Wan
mpicbs.bsky.social
The human 🧠 has two halves that make our behaviors and thoughts more efficient. How the asymmetry of the brain halves contributes to human cognition, examined @wanb.bsky.social & @sofievalk.bsky.social in their study in Nature Communications: www.cbs.mpg.de/2316389/2024...
How asymmetry of brain halves contributes to human cognition
How asymmetry of brain halves contributes to human cognition
www.cbs.mpg.de
December 3, 2024 at 10:39 AM
wanb.bsky.social
Thrilled to share my latest work "Microstructural asymmetry in the human cortex" now out in NatComms. www.nature.com/articles/s41...
This work used cytoarchitecture (BigBrain), T1w/T2w, qT1, and MT measures to bring the cortical asymmetry from macrostructure to microstructure.
Microstructural asymmetry in the human cortex - Nature Communications
The human cortex displays an anterior-to-posterior asymmetry, identified via both post-mortem and in vivo microstructural measurements. Microstructural asymmetry is heritable, varies across cortical l...
www.nature.com
November 25, 2024 at 12:41 PM