Bin Wan
@wanb.bsky.social
Computational Neurogenetics
PostDoc @ Geneva Psychiatry
PhD @mpicbs.bsky.social
Personal web: https://wanb-psych.netlify.app/
PostDoc @ Geneva Psychiatry
PhD @mpicbs.bsky.social
Personal web: https://wanb-psych.netlify.app/
Pinned
Bin Wan
@wanb.bsky.social
· Mar 5
Happy to share my last PhD work "Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients". We used UKB, HCP, and QTAB to analyze the genetics of functional gradients. The results are so good, consistent, and inspiring! (1/3)
Reposted by Bin Wan
✨ New preprint ✨
Introducing cuBNM, a toolbox we developed to run brain simulations *much* more efficiently on GPUs 🎉🚀
Preprint: www.biorxiv.org/content/10.1...
Documentation: cubnm.readthedocs.io/en/stable/
GitHub: github.com/amnsbr/cubnm
1/n 🧵
Introducing cuBNM, a toolbox we developed to run brain simulations *much* more efficiently on GPUs 🎉🚀
Preprint: www.biorxiv.org/content/10.1...
Documentation: cubnm.readthedocs.io/en/stable/
GitHub: github.com/amnsbr/cubnm
1/n 🧵
November 14, 2025 at 5:29 PM
✨ New preprint ✨
Introducing cuBNM, a toolbox we developed to run brain simulations *much* more efficiently on GPUs 🎉🚀
Preprint: www.biorxiv.org/content/10.1...
Documentation: cubnm.readthedocs.io/en/stable/
GitHub: github.com/amnsbr/cubnm
1/n 🧵
Introducing cuBNM, a toolbox we developed to run brain simulations *much* more efficiently on GPUs 🎉🚀
Preprint: www.biorxiv.org/content/10.1...
Documentation: cubnm.readthedocs.io/en/stable/
GitHub: github.com/amnsbr/cubnm
1/n 🧵
Reposted by Bin Wan
It's a wrap! BIG thanks to all speakers, chairs, attendees, and our organizing committee - particularly our superstar local organizers Johan and Saurabh - for making our gradient dreams come true for the sixth year in a row ⭐ 🌈 🧠 🚀
June 23, 2025 at 9:28 AM
It's a wrap! BIG thanks to all speakers, chairs, attendees, and our organizing committee - particularly our superstar local organizers Johan and Saurabh - for making our gradient dreams come true for the sixth year in a row ⭐ 🌈 🧠 🚀
Reposted by Bin Wan
🎉🎉#OHBM2025 is just around the corner! Remember to visit the SP-SIG stall next to the registration desk and add stickers to your badge describing your research interests!
June 22, 2025 at 4:29 AM
🎉🎉#OHBM2025 is just around the corner! Remember to visit the SP-SIG stall next to the registration desk and add stickers to your badge describing your research interests!
I finally defended my thesis! Thanks all! I started my PhD during covid! I am really grateful that my supervisor @sofievalk.bsky.social picked me to be her first PhD student when I was naive to neuroimage. I have been so lucky to stay in this happy and respectful academic environment so far!
June 20, 2025 at 8:56 AM
I finally defended my thesis! Thanks all! I started my PhD during covid! I am really grateful that my supervisor @sofievalk.bsky.social picked me to be her first PhD student when I was naive to neuroimage. I have been so lucky to stay in this happy and respectful academic environment so far!
Reposted by Bin Wan
An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Benchmarking methods for mapping functional connectivity in the brain - Nature Methods
In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...
www.nature.com
June 6, 2025 at 3:51 PM
An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Bin Wan
🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling
Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.
www.science.org
June 5, 2025 at 7:53 AM
🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️
Reposted by Bin Wan
Merchant et al. perform a meta-analytic investigation of neurocognitive systems involved in real-time social interaction doi.org/10.52294/001...
@fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social
@fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social
June 2, 2025 at 2:27 PM
Merchant et al. perform a meta-analytic investigation of neurocognitive systems involved in real-time social interaction doi.org/10.52294/001...
@fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social
@fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social
Reposted by Bin Wan
🚨🚨🚨PREPRINT ALERT🚨🚨🚨
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!
June 2, 2025 at 11:55 AM
🚨🚨🚨PREPRINT ALERT🚨🚨🚨
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!
Reposted by Bin Wan
🎨🧑🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊
anniegbryant.github.io/subcortex_vi...
anniegbryant.github.io/subcortex_vi...
May 4, 2025 at 10:13 AM
🎨🧑🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊
anniegbryant.github.io/subcortex_vi...
anniegbryant.github.io/subcortex_vi...
See our GWAS of grapical topology🤟
Pleased to share new work from our group, led by PhD student Edward He. Edward joined the group as a summer student interested in the genetics of resting state functional connectivity, measured using graph networks.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
www.medrxiv.org
April 29, 2025 at 1:01 PM
See our GWAS of grapical topology🤟
Reposted by Bin Wan
As always, it was great fun to connect with our ENIGMA Consortium community last night at #SOBP2025 in Toronto - thanks to all who joined us! Cheers to science and the next SOBP conference🍻🧠
April 25, 2025 at 2:45 PM
As always, it was great fun to connect with our ENIGMA Consortium community last night at #SOBP2025 in Toronto - thanks to all who joined us! Cheers to science and the next SOBP conference🍻🧠
Reposted by Bin Wan
in press @natcomms.nature.com 🌟
"Multimodal gradients unify local and global cortical organization"
7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration
led by superstar Yezhou Wang & a terrific team of friends & colleagues
▶️ doi.org/10.1038/s414...
"Multimodal gradients unify local and global cortical organization"
7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration
led by superstar Yezhou Wang & a terrific team of friends & colleagues
▶️ doi.org/10.1038/s414...
April 25, 2025 at 12:58 PM
in press @natcomms.nature.com 🌟
"Multimodal gradients unify local and global cortical organization"
7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration
led by superstar Yezhou Wang & a terrific team of friends & colleagues
▶️ doi.org/10.1038/s414...
"Multimodal gradients unify local and global cortical organization"
7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration
led by superstar Yezhou Wang & a terrific team of friends & colleagues
▶️ doi.org/10.1038/s414...
Reposted by Bin Wan
Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
Multimodal precision MRI of the individual human brain at ultra-high fields - Scientific Data
Scientific Data - Multimodal precision MRI of the individual human brain at ultra-high fields
www.nature.com
March 30, 2025 at 1:38 PM
Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
forget the most important thing 😱
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients
Functional gradients capture the organization of functional activity in the cerebral cortex, delineating transitions from sensory to higher-order association areas. While group-level gradient patterns...
www.medrxiv.org
March 5, 2025 at 11:00 AM
forget the most important thing 😱
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
here is the link: www.medrxiv.org/content/10.1...
Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients
Functional gradients capture the organization of functional activity in the cerebral cortex, delineating transitions from sensory to higher-order association areas. While group-level gradient patterns...
www.medrxiv.org
March 5, 2025 at 10:59 AM
here is the link: www.medrxiv.org/content/10.1...
Thanks for the coauthors! Yuankai He, Varun Warrier, @johnalexandra.bsky.social, Matthias Kirschner, @sbe.bsky.social, @raibethlehem.bsky.social, @sofievalk.bsky.social (3/3).
March 5, 2025 at 10:31 AM
Thanks for the coauthors! Yuankai He, Varun Warrier, @johnalexandra.bsky.social, Matthias Kirschner, @sbe.bsky.social, @raibethlehem.bsky.social, @sofievalk.bsky.social (3/3).
1) The heritability was robust across samples of different ages
2) GWAS identified 16 genes, involved in metabolic process
3) The genes were further validated using Allen Brain
4) Individual protective and risk metabolic makers showed reversed correlations
5) SCZ, PTSD, and BP won the game
(2/3)
2) GWAS identified 16 genes, involved in metabolic process
3) The genes were further validated using Allen Brain
4) Individual protective and risk metabolic makers showed reversed correlations
5) SCZ, PTSD, and BP won the game
(2/3)
March 5, 2025 at 10:28 AM
1) The heritability was robust across samples of different ages
2) GWAS identified 16 genes, involved in metabolic process
3) The genes were further validated using Allen Brain
4) Individual protective and risk metabolic makers showed reversed correlations
5) SCZ, PTSD, and BP won the game
(2/3)
2) GWAS identified 16 genes, involved in metabolic process
3) The genes were further validated using Allen Brain
4) Individual protective and risk metabolic makers showed reversed correlations
5) SCZ, PTSD, and BP won the game
(2/3)
Happy to share my last PhD work "Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients". We used UKB, HCP, and QTAB to analyze the genetics of functional gradients. The results are so good, consistent, and inspiring! (1/3)
March 5, 2025 at 10:21 AM
Happy to share my last PhD work "Genetic, transcriptomic, metabolic, and neuropsychiatric underpinnings of cortical functional gradients". We used UKB, HCP, and QTAB to analyze the genetics of functional gradients. The results are so good, consistent, and inspiring! (1/3)
Reposted by Bin Wan
🧠 The GINNA brain atlas offers a comprehensive framework for exploring the functional significance of 33 resting-state networks & their relationship to human cognition.
@imn-bordeaux.bsky.social @achetyl.bsky.social
www.nature.com/articles/s42...
@imn-bordeaux.bsky.social @achetyl.bsky.social
www.nature.com/articles/s42...
GINNA, a 33 resting-state networks atlas with meta-analytic decoding-based cognitive characterization - Communications Biology
The GINNA brain atlas offers a comprehensive framework for exploring the functional significance of 33 resting-state networks and their relationship to human cognition, using task-based meta-analytic ...
www.nature.com
February 18, 2025 at 7:08 PM
🧠 The GINNA brain atlas offers a comprehensive framework for exploring the functional significance of 33 resting-state networks & their relationship to human cognition.
@imn-bordeaux.bsky.social @achetyl.bsky.social
www.nature.com/articles/s42...
@imn-bordeaux.bsky.social @achetyl.bsky.social
www.nature.com/articles/s42...
Reposted by Bin Wan
For all the thalamus lovers❤️🔥 : Excited to share that our Paper is out now✨Huge thanks to @sofievalk.bsky.social and all collaborators @meikehettwer.bsky.social, @wanb.bsky.social, @amnsbr.bsky.social, @jroyer.bsky.social, @borismontreal.bsky.social, @linaschaare.bsky.social, Seyma Bayrak
Low-dimensional axes derived from thalamocortical connectivity align with intrathalamic microstructure, functional connectivity, and structural covariance, shedding light on the multimodal organization of the human thalamus.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
A multimodal characterization of low-dimensional thalamocortical structural connectivity patterns - Communications Biology
Low-dimensional axes derived from thalamocortical connectivity align with intrathalamic microstructure, functional connectivity, and structural covariance, shedding light on the multimodal organizatio...
www.nature.com
February 7, 2025 at 12:38 PM
For all the thalamus lovers❤️🔥 : Excited to share that our Paper is out now✨Huge thanks to @sofievalk.bsky.social and all collaborators @meikehettwer.bsky.social, @wanb.bsky.social, @amnsbr.bsky.social, @jroyer.bsky.social, @borismontreal.bsky.social, @linaschaare.bsky.social, Seyma Bayrak