after 2015, biomedical evidence supporting a target-disease indication increasingly appears before the approval year
www.nature.com/articles/s41...
after 2015, biomedical evidence supporting a target-disease indication increasingly appears before the approval year
www.nature.com/articles/s41...
registry.opendata.aws/opentargets/
registry.opendata.aws/opentargets/
With a redesigned interface, richer datasets and powerful analysis workflows, it’s now easier than ever to explore genetic perturbation data. www.ebi.ac.uk/perturbation...
#Bioinformatics #FunctionalGenomics
@training.ebi.embl.org @opentargets.org
With a redesigned interface, richer datasets and powerful analysis workflows, it’s now easier than ever to explore genetic perturbation data. www.ebi.ac.uk/perturbation...
#Bioinformatics #FunctionalGenomics
@training.ebi.embl.org @opentargets.org
It aims to bring genetic perturbation data into one curated, harmonised, and discoverable platform.
Take a look! www.ebi.ac.uk/perturbation...
It aims to bring genetic perturbation data into one curated, harmonised, and discoverable platform.
Take a look! www.ebi.ac.uk/perturbation...
Find out more about the Open Targets Platform MCP server: blog.opentargets.org/official-ope...
Find out more about the Open Targets Platform MCP server: blog.opentargets.org/official-ope...
Our solution? A time-series novelty metric for Open Targets Platform associations.
Thanks to Coté Falaguera & @opentargets.org partners for making this happen.
An Open Targets team developed a metric for the novelty of a target in the context of a disease, according to current available knowledge.
This allows drug discovery scientists to easily identify potentially novel targets
www.nature.com/articles/s41...
Our solution? A time-series novelty metric for Open Targets Platform associations.
Thanks to Coté Falaguera & @opentargets.org partners for making this happen.
An Open Targets team developed a metric for the novelty of a target in the context of a disease, according to current available knowledge.
This allows drug discovery scientists to easily identify potentially novel targets
www.nature.com/articles/s41...
An Open Targets team developed a metric for the novelty of a target in the context of a disease, according to current available knowledge.
This allows drug discovery scientists to easily identify potentially novel targets
www.nature.com/articles/s41...
Loss of CHD1 and MAP3K7 creates an acquired cancer vulnerability, highlighting these genes as potential biomarkers of immune checkpoint blockade response
Find out more: www.cell.com/cell-reports...
Loss of CHD1 and MAP3K7 creates an acquired cancer vulnerability, highlighting these genes as potential biomarkers of immune checkpoint blockade response
Find out more: www.cell.com/cell-reports...
Researchers found that loss of two genes, CHD1 and MAP3K7, makes tumours more likely to respond to immunotherapy.
The findings could help support more personalised cancer treatment 👇
bit.ly/4sMBTq2
Researchers found that loss of two genes, CHD1 and MAP3K7, makes tumours more likely to respond to immunotherapy.
The findings could help support more personalised cancer treatment 👇
bit.ly/4sMBTq2
NEW:
➡ Postdoc with @carlanderson.bsky.social
➡ Technical Specialist with @bayraktarlab.bsky.social
ALSO:
➡ (Senior) Postdoc in Mo Lotfollahi’s lab
More information in the thread
See all available jobs: opentargets.org/jobs
NEW:
➡ Postdoc with @carlanderson.bsky.social
➡ Technical Specialist with @bayraktarlab.bsky.social
ALSO:
➡ (Senior) Postdoc in Mo Lotfollahi’s lab
More information in the thread
See all available jobs: opentargets.org/jobs
We've partnered with @anthropic.com to give AI seamless access to high-quality genetic and target-discovery data. Open for the entire community to accelerate therapeutic development.
Read more at blog.opentargets.org/official-ope...
We've partnered with @anthropic.com to give AI seamless access to high-quality genetic and target-discovery data. Open for the entire community to accelerate therapeutic development.
Read more at blog.opentargets.org/official-ope...
In partnership with @anthropic.com, we’ve created an MCP server making Open Targets Platform data accessible to AI-powered tools and agents
Try it out and watch out for future releases: mcp.platform.opentargets.org/mcp
In partnership with @anthropic.com, we’ve created an MCP server making Open Targets Platform data accessible to AI-powered tools and agents
Try it out and watch out for future releases: mcp.platform.opentargets.org/mcp
📸 Helena Cornu
📸 Helena Cornu
Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities
Apply by 11 January
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities
Apply by 11 January
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Thanks to a GWAS Catalog update including 3 major studies using UK Biobank data, we now have over 1.4 million GWAS credible sets in the Platform.
Discover the data, feature, and technical updates in this release: blog.opentargets.org/open-targets... 🧬🖥️
Thanks to a GWAS Catalog update including 3 major studies using UK Biobank data, we now have over 1.4 million GWAS credible sets in the Platform.
Discover the data, feature, and technical updates in this release: blog.opentargets.org/open-targets... 🧬🖥️
There are many research focus areas available, including Open Targets translational AI projects
Apply now: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
There are many research focus areas available, including Open Targets translational AI projects
Apply now: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
Perform large-scale phenotypic CRISPR screens on human iPSC-derived microglia to identify modifiers of immune dysfunction relating to neurodegeneration 🧬
Apply by 11 January: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
#ScienceJobs
Perform large-scale phenotypic CRISPR screens on human iPSC-derived microglia to identify modifiers of immune dysfunction relating to neurodegeneration 🧬
Apply by 11 January: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
#ScienceJobs
Meet Lit-OTAR, a deep learning framework built by Europe PMC and @opentargets.org
It’s identified >48.5 million unique associations, accelerating the drug discovery process!
Read the thread for a paper summary👇
#AI4Science #BioNLP #DrugDiscovery
Meet Lit-OTAR, a deep learning framework built by Europe PMC and @opentargets.org
It’s identified >48.5 million unique associations, accelerating the drug discovery process!
Read the thread for a paper summary👇
#AI4Science #BioNLP #DrugDiscovery
Benchmark and integrate state-of-the-art network contextualisation methods, combining large-scale transcriptomics, proteomics, and single-cell data
Apply by 17 Dec
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Benchmark and integrate state-of-the-art network contextualisation methods, combining large-scale transcriptomics, proteomics, and single-cell data
Apply by 17 Dec
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Findings from this project will be integrated into the Open Targets Platform to help identify and prioritise the most promising therapeutic targets.
Findings from this project will be integrated into the Open Targets Platform to help identify and prioritise the most promising therapeutic targets.
The Open Psychiatry Project aims to change that with a secure platform linking genetic and clinical mental health data.
@cam.ac.uk @opentargets.org
www.ebi.ac.uk/about/news/a...
The Open Psychiatry Project aims to change that with a secure platform linking genetic and clinical mental health data.
@cam.ac.uk @opentargets.org
www.ebi.ac.uk/about/news/a...
Thank you to everyone who joined in person and online, and who contributed to make this event a success
Particular thanks to our sponsors: Gates Foundation, Google Cloud, and @thehyvenl.bsky.social 🎉
Thank you to everyone who joined in person and online, and who contributed to make this event a success
Particular thanks to our sponsors: Gates Foundation, Google Cloud, and @thehyvenl.bsky.social 🎉
Following our official kick off yesterday, there was some incredible energy and focus in the room
Thanks to our sponsors Gates Foundation, Google Cloud, and @thehyvenl.bsky.social for making this possible!
Following our official kick off yesterday, there was some incredible energy and focus in the room
Thanks to our sponsors Gates Foundation, Google Cloud, and @thehyvenl.bsky.social for making this possible!