Omkar Joshi
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omkarjoshi.bsky.social
Omkar Joshi
@omkarjoshi.bsky.social
270 followers 190 following 8 posts
Doctoral Researcher in @ivaskalab.bsky.social 🇫🇮 | BS-MS from IISER, Pune 🇮🇳 | Cancer, Cells and Mitochondria | Badminton and cricket!
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Reposted by Omkar Joshi
helloeacr.bsky.social
EACR Board members and other key opinion leaders author regular EACR Viewpoint articles for publication in our affiliated journal @moloncology.bsky.social 🧠

Catch up with all the EACR Viewpoints published to date: febs.onlinelibrary.wiley.com/doi/toc/10.1...
October 27, 2025 at 3:32 PM
Reposted by Omkar Joshi
sgabriele.bsky.social
Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳

Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻

Enjoy the reading www.nature.com/articles/s41...
The actin cortex acts as a mechanical memory of morphology in confined migrating cells - Nature Physics
Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenv...
www.nature.com
August 25, 2025 at 9:59 AM
Reposted by Omkar Joshi
ritastrack.bsky.social
I have some BIG NEWS to share today!

Today I begin my next adventure as

Chief Editor of Nature Biomedical Engineering!!

(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com
a bunch of balloons are flying in the sky .
ALT: a bunch of balloons are flying in the sky .
media.tenor.com
August 1, 2025 at 2:27 PM
omkarjoshi.bsky.social
Wow
July 17, 2025 at 11:51 AM
Reposted by Omkar Joshi
guijacquemet.bsky.social
Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
June 23, 2025 at 2:29 PM
Reposted by Omkar Joshi
gounismichalis.bsky.social
1/ Beyond thrilled to see my #PhD work now published in @jcb.org
A short thread (🧵) for #metastasis #metabolism #ExtracellularVesicles (EVs) aficionados
jcb.org Journal of Cell Biology @jcb.org · Jun 9
@gounismichalis.bsky.social‬ et al. show that cells that seed early lung #metastasis in #BreastCancer have altered #metabolism. These metabolic alterations lead them to release extracellular vesicles which engender a microenvironment conducive to invasive growth. rupress.org/jcb/article/...
June 9, 2025 at 8:25 PM
Reposted by Omkar Joshi
jcb.org
@gounismichalis.bsky.social‬ et al. show that cells that seed early lung #metastasis in #BreastCancer have altered #metabolism. These metabolic alterations lead them to release extracellular vesicles which engender a microenvironment conducive to invasive growth. rupress.org/jcb/article/...
June 9, 2025 at 4:07 PM
Reposted by Omkar Joshi
johannaivaska.bsky.social
Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation!

Read more at:

www.nature.com/articles/s41...
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology
Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...
www.nature.com
May 26, 2025 at 12:16 PM
Reposted by Omkar Joshi
jrwconway.bsky.social
New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...
May 26, 2025 at 10:29 AM
Reposted by Omkar Joshi
ivaskalab.bsky.social
Our newest paper is out in NCB. @jrwconway.bsky.social‬ designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...
May 26, 2025 at 10:13 AM
omkarjoshi.bsky.social
Amazing news! Warm congratulations to @johannaivaska.bsky.social for the award. Super proud!

www.utu.fi/en/news/news...
May 20, 2025 at 12:56 PM
Reposted by Omkar Joshi
nabalabuic.bsky.social
📣 Pre-print alert: Excited to have collaborated with Pam Kreeger and Kristyn Masters on this study showing that fibronectin composition and transglutaminase 2 crosslinking cooperatively regulate ovarian cancer cell adhesion in ECM-mimetic constructs.
www.biorxiv.org/content/10.1...
Collagen content of the human omentum and human omental HGSOC metastasis.
May 17, 2025 at 9:07 PM
Reposted by Omkar Joshi
ivaskalab.bsky.social
New preprint alert!📣 @midibu.bsky.social and team take a deep dive into Tensin1 liquid-liquid phase separation (LLPS) and the mechanisms of how it regulates adhesion dynamics!
Check out the preprint here: www.biorxiv.org/content/10.1...
@johannaivaska.bsky.social
Adhesion-derived condensates control component availability to regulate adhesion dynamics
Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...
www.biorxiv.org
May 10, 2025 at 7:37 AM
Reposted by Omkar Joshi
midibu.bsky.social
Happy to share our Tensin 1 phase separation project is now on bioRxiv.
www.biorxiv.org/content/10.1...

This wouldn't be possible without
@johannaivaska.bsky.social
@ivaskalab.bsky.social
#VattulainenLab
#MSCA by @ec.europa.eu
@turkubioscience.bsky.social
@inflames-flagship.bsky.social
Adhesion-derived condensates control component availability to regulate adhesion dynamics
Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...
www.biorxiv.org
May 9, 2025 at 2:23 PM
omkarjoshi.bsky.social
I'm at the Fibronectin GRC till the end of the week! Come say hi and I'll tell you a bit about mitochondrial near focal adhesions😉
May 7, 2025 at 6:50 AM
Reposted by Omkar Joshi
tanentzapflab.bsky.social
A reminder to colleagues interested in Cell-Matrix adhesion & anything ECM related that registration is now open for the Fibronectin, Integrins & related molecules Gordon Research Conference. Incredible list speakers! incredible location! it will 🔥 🔥 🔥 Please join us! www.grc.org/fibronectin-...
2025 Fibronectin, Integrins and Related Molecules Conference GRC
The 2025 Gordon Research Conference on Fibronectin, Integrins and Related Molecules will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
www.grc.org
January 22, 2025 at 4:54 AM
Reposted by Omkar Joshi
midibu.bsky.social
Grateful for the opportunity to participate in this Viewpoint with @follainga.bsky.social , @omkarjoshi.bsky.social and @guijacquemet.bsky.social :
Time, the final frontier
doi.org/10.1002/1878...
March 26, 2025 at 8:35 AM
Reposted by Omkar Joshi
guijacquemet.bsky.social
We wrote a small Viewpoint for Molecular Oncology with
@follainga.bsky.social

@omkarjoshi.bsky.social

Michal Dibus

via EACR
@helloeacr.bsky.social

Time, the final frontier
febs.onlinelibrary.wiley.com/doi/full/10....

Hope you find it interesting
febs.onlinelibrary.wiley.com
March 24, 2025 at 2:54 PM
Reposted by Omkar Joshi
jcb.org
In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...
March 21, 2025 at 4:18 PM
Reposted by Omkar Joshi
samstehbens.bsky.social
If you are planning your conferences for the year- keep an eye out for EACR’s Goodbye Flat Biology! Essen 23-25 Sept 2025
www.eacr.org/conference/goodbyeflatbiology2025

#CancerResearch #Oncology I’ll see you there. :)
@helloeacr.bsky.social
March 22, 2025 at 12:21 AM
Reposted by Omkar Joshi
epeuhu.bsky.social
We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social
March 20, 2025 at 2:04 PM
omkarjoshi.bsky.social
Thank you @focalplane.bsky.social for featuring my image!
March 14, 2025 at 11:36 AM
Reposted by Omkar Joshi
turkubioscience.bsky.social
🎉 Great success for Turku Bioscience Centre at the 3MT competition!

Congrats to Rahul Birdar (@lahesmaalab.bsky.social) for securing 2nd place and Omkar Joshi (@ivaskalab.bsky.social) for being selected to represent @utu.fi in the international 3MT competition by the SANORD network! 👏 #3MT #SANORD
March 7, 2025 at 10:01 AM
Reposted by Omkar Joshi
odedrechavi.bsky.social
Friends! The science that we love is under threat. World-wide, there're forces seeking to make it corporate-like, focused on deliverables, or even the enemy of society. Take a stand & celebrate science & music! #theconferencetoendallconferences - Registration starts NOW!
woodstock.img.cas.cz
March 1, 2025 at 5:44 PM
Reposted by Omkar Joshi
helenkmatthews.bsky.social
🚨 PhD position available for Oct 25

🔬Using advanced microscopy to understand how keratin networks control tissue mechanics

An interdisciplinary #cellbiology #biophysics collaboration with Ruby Peters & @alicepyne.bsky.social

👇 Apply by March 14

www.findaphd.com/phds/project...
Micrograph of keratin networks (green) and DNA (blue) within cells Image by Rachel Lawson
February 24, 2025 at 3:29 PM