Otto
@okalliokoski.bsky.social
Pre-clinical medicine. Animal welfare. Meta-research. Sentient potato.
Reposted by Otto
So I thought that Elsevier was already as enshittified as possible. I was wrong.
November 4, 2025 at 4:19 AM
So I thought that Elsevier was already as enshittified as possible. I was wrong.
Reposted by Otto
"We included 608 articles, of which 243 articles were identified as problematic (40.0%)." (bit.ly/3X4PtGF) This finding of so many image-related problems by a team that wanted to do a systemic review, is deeply concerning.
October 31, 2025 at 9:41 AM
"We included 608 articles, of which 243 articles were identified as problematic (40.0%)." (bit.ly/3X4PtGF) This finding of so many image-related problems by a team that wanted to do a systemic review, is deeply concerning.
Reposted by Otto
arXiv will no longer accept review articles and position papers unless they have been accepted at a journal or a conference and complete successful peer review.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
Attention Authors: Updated Practice for Review Articles and Position Papers in arXiv CS Category – arXiv blog
blog.arxiv.org
November 1, 2025 at 5:28 PM
arXiv will no longer accept review articles and position papers unless they have been accepted at a journal or a conference and complete successful peer review.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
Reposted by Otto
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
A LEAP into the future, or off a cliff: Wellcome LEAP's new $50M program
A few days ago, I saw this post on LinkedIn: How does the gut microbiome shape early brain development? That’s what FORM, a new $50 million...
deevybee.blogspot.com
October 20, 2025 at 1:53 PM
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
Reposted by Otto
📢Nominations are now open for the UFAW Medal for Outstanding Contributions to #AnimalWelfareScience!
Do you know an individual whose research, teaching, service, or advocacy has significantly benefited the welfare of animals? Nominate them here: ow.ly/Bs7b50X3ENT
📅 Nominations close 10 December
Do you know an individual whose research, teaching, service, or advocacy has significantly benefited the welfare of animals? Nominate them here: ow.ly/Bs7b50X3ENT
📅 Nominations close 10 December
October 1, 2025 at 8:39 AM
📢Nominations are now open for the UFAW Medal for Outstanding Contributions to #AnimalWelfareScience!
Do you know an individual whose research, teaching, service, or advocacy has significantly benefited the welfare of animals? Nominate them here: ow.ly/Bs7b50X3ENT
📅 Nominations close 10 December
Do you know an individual whose research, teaching, service, or advocacy has significantly benefited the welfare of animals? Nominate them here: ow.ly/Bs7b50X3ENT
📅 Nominations close 10 December
Reposted by Otto
Open Science Workshop - detecting errors and misconduct in science
Dates: 20-22 October
Location: Radboud University, Nijmegen, The Netherlands
Registration link: tinyurl.com/3xkd8twf
ONLY PHYSICAL ATTENDENCE POSSIBLE! NO ONLINE POSSIBILITIES.
Dates: 20-22 October
Location: Radboud University, Nijmegen, The Netherlands
Registration link: tinyurl.com/3xkd8twf
ONLY PHYSICAL ATTENDENCE POSSIBLE! NO ONLINE POSSIBILITIES.
September 29, 2025 at 10:38 AM
Open Science Workshop - detecting errors and misconduct in science
Dates: 20-22 October
Location: Radboud University, Nijmegen, The Netherlands
Registration link: tinyurl.com/3xkd8twf
ONLY PHYSICAL ATTENDENCE POSSIBLE! NO ONLINE POSSIBILITIES.
Dates: 20-22 October
Location: Radboud University, Nijmegen, The Netherlands
Registration link: tinyurl.com/3xkd8twf
ONLY PHYSICAL ATTENDENCE POSSIBLE! NO ONLINE POSSIBILITIES.
Reposted by Otto
In discussion with a computer scientist from the University of Cambridge last night:
Me: "you've described some of the things that AI is good at. How would you describe the category of things it's not good at?
**pause**
Him: "Anything where it has to be right".
Me: "you've described some of the things that AI is good at. How would you describe the category of things it's not good at?
**pause**
Him: "Anything where it has to be right".
September 26, 2025 at 5:14 PM
In discussion with a computer scientist from the University of Cambridge last night:
Me: "you've described some of the things that AI is good at. How would you describe the category of things it's not good at?
**pause**
Him: "Anything where it has to be right".
Me: "you've described some of the things that AI is good at. How would you describe the category of things it's not good at?
**pause**
Him: "Anything where it has to be right".
Reposted by Otto
Please RT
2 new positions in the lab as postdoc & PhD!
Interested in stress, pain, or reward? This project has it all!
We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶
www.jobbnorge.no/en/available...
2 new positions in the lab as postdoc & PhD!
Interested in stress, pain, or reward? This project has it all!
We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶
www.jobbnorge.no/en/available...
Postdoctoral Research Fellowship (286516) | University of Oslo
Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025
www.jobbnorge.no
September 24, 2025 at 12:22 PM
Please RT
2 new positions in the lab as postdoc & PhD!
Interested in stress, pain, or reward? This project has it all!
We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶
www.jobbnorge.no/en/available...
2 new positions in the lab as postdoc & PhD!
Interested in stress, pain, or reward? This project has it all!
We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶
www.jobbnorge.no/en/available...
Reposted by Otto
You’re think *you’re* depressed? Try being at the annual meeting of the American Political Science Association right now with 5,000 political scientists presenting their work on the state of democracy, public opinion, and media.
They are also drinking heavily.
They are also drinking heavily.
September 13, 2025 at 5:47 AM
You’re think *you’re* depressed? Try being at the annual meeting of the American Political Science Association right now with 5,000 political scientists presenting their work on the state of democracy, public opinion, and media.
They are also drinking heavily.
They are also drinking heavily.
Reposted by Otto
Orson Welles would murder every one of you motherfuckers with a hammer.
Orson Welles’ Lost Movie Will Use AI to Reconstruct Missing 43 Minutes
Orson Welles’ Lost Movie Will Use AI to Reconstruct Missing 43 Minutes
Since the rise of generative artificial intelligence in 2022, the technology has mostly been plugged into parts of the production pipeline as far as its deployment in Hollywood. Think visual effects, dubbing and storyboarding. As it stands, it’s mostly thought of as a tool to streamline certain processes and cut costs.
bit.ly
September 6, 2025 at 4:20 AM
Orson Welles would murder every one of you motherfuckers with a hammer.
Reposted by Otto
IMO the strongest challenge against your view is that the sludge does in fact pollute meta-analyses and systematic reviews (an issue which is likely to grow as evidence synthesis becomes more AI-assisted) Cf e.g. www.nature.com/articles/d41...
Giant study finds untrustworthy trials pollute gold-standard medical reviews
Two-year collaboration aims to create tools to help counter the tide of flawed research.
www.nature.com
August 6, 2025 at 8:42 AM
IMO the strongest challenge against your view is that the sludge does in fact pollute meta-analyses and systematic reviews (an issue which is likely to grow as evidence synthesis becomes more AI-assisted) Cf e.g. www.nature.com/articles/d41...
Reposted by Otto
when i'm asked to review the revised version
July 19, 2025 at 3:56 AM
when i'm asked to review the revised version
Reposted by Otto
A guide to academic event names
July 13, 2025 at 12:06 PM
A guide to academic event names
Reposted by Otto
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
July 10, 2025 at 8:23 AM
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
Reposted by Otto
There is no scientific concept of "real world" data or evidence - there is nothing about this terminology that can't be more accurately and honestly conveyed using other accepted methodological terms.
We've frustratingly allowed "real world" to become a deceptive synonym for "observations we happened haphazardly to make". I'd say half the studies that come to me now, the majority of which are useful but modest clinical audits, will have "real world" in the proposal title. It's magic!
July 7, 2025 at 11:42 AM
There is no scientific concept of "real world" data or evidence - there is nothing about this terminology that can't be more accurately and honestly conveyed using other accepted methodological terms.
Reposted by Otto
This Delphi is live! Invitations are rolling out. Contact me if you have expertise in trials and would like to participate.
Funders expect evidence of 'promise' (the intervention is likely to work) when considering whether to fund an RCT, pilot, or feasibility study. But there is no shared understanding of how we should do this. We have been funded by @nihr.bsky.social to develop guidance to help.
July 4, 2025 at 6:44 PM
This Delphi is live! Invitations are rolling out. Contact me if you have expertise in trials and would like to participate.
Reposted by Otto
Help me find a paper!
I think it came out 5-10 years ago, and it showed that academic psychologists (or maybe social scientists) had trouble interpreting complex statistical interactions, and couldn't explain a 4-way interaction.
1/2
#openscience #psychology #metascience #statistics
I think it came out 5-10 years ago, and it showed that academic psychologists (or maybe social scientists) had trouble interpreting complex statistical interactions, and couldn't explain a 4-way interaction.
1/2
#openscience #psychology #metascience #statistics
July 1, 2025 at 1:30 PM
Help me find a paper!
I think it came out 5-10 years ago, and it showed that academic psychologists (or maybe social scientists) had trouble interpreting complex statistical interactions, and couldn't explain a 4-way interaction.
1/2
#openscience #psychology #metascience #statistics
I think it came out 5-10 years ago, and it showed that academic psychologists (or maybe social scientists) had trouble interpreting complex statistical interactions, and couldn't explain a 4-way interaction.
1/2
#openscience #psychology #metascience #statistics
Reposted by Otto
I spoke to @raphavisses.bsky.social about how he blew the whistle on a colleague — my latest for @chemistryworld.com: www.chemistryworld.com/news/how-i-b...
How I blew the whistle on a fellow chemist and colleague
Raphaël Lévy talks to Chemistry World about reporting Jolanda Spadavecchia, the backlash he faced and how misconduct should be investigated
www.chemistryworld.com
June 18, 2025 at 3:16 PM
I spoke to @raphavisses.bsky.social about how he blew the whistle on a colleague — my latest for @chemistryworld.com: www.chemistryworld.com/news/how-i-b...
It's been a long journey, but our study of (potentially) fraudulent studies in preclinical medicine is finally out as a peer-reviewed paper!
🧑🔬 New in the Scientists Forum: #ResearchFraud and problematic images are undermining #SystematicReviews.
Jenny P. Berrío and @okalliokoski.bsky.social identified issues with 19% of studies for a review on #PreclinicalDepression.
➡️ doi.org/10.1002/1873-3468.70077
#ResearchIntegrity #PaperMills
Jenny P. Berrío and @okalliokoski.bsky.social identified issues with 19% of studies for a review on #PreclinicalDepression.
➡️ doi.org/10.1002/1873-3468.70077
#ResearchIntegrity #PaperMills
June 17, 2025 at 1:58 PM
It's been a long journey, but our study of (potentially) fraudulent studies in preclinical medicine is finally out as a peer-reviewed paper!
This is the way to go. We should celebrate also our null results! We are not our hypotheses and if we get to anxious about being right all the time, we become worse and more cowardly scientists.
A *null* result I'm very proud of!
Led by Rustam Romaniuc, 35 coauthors from all over France tested nudge interventions to boost voter turnout.
None worked, and we are possibly not surprised -- but a well-powered null result *is* a result!
Paper:
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Led by Rustam Romaniuc, 35 coauthors from all over France tested nudge interventions to boost voter turnout.
None worked, and we are possibly not surprised -- but a well-powered null result *is* a result!
Paper:
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
June 15, 2025 at 11:26 AM
This is the way to go. We should celebrate also our null results! We are not our hypotheses and if we get to anxious about being right all the time, we become worse and more cowardly scientists.
Reposted by Otto
Freshly published: In this study we show that it is possible to use voluntary intake protocols (e.g. with sweet condensed milk) in reward related behavioural testing #behaviour #mda #refinement
Applicability of the micropipette-guided drug administration (MDA) method for assessing reward-related behaviors in mice
Oral gavage is the standard method for acute or chronic per os treatments in laboratory rodents. It can, however, induce significant stress responses …
www.sciencedirect.com
June 5, 2025 at 8:39 AM
Freshly published: In this study we show that it is possible to use voluntary intake protocols (e.g. with sweet condensed milk) in reward related behavioural testing #behaviour #mda #refinement
Finally!
May 28, 2025 at 6:02 PM
Finally!
Reposted by Otto
Top quality teamwork by @cost-teatime.bsky.social repositories WG to address a key issue in maximising the impact of #Home-cageMonitoring. From the first working group meeting @mrcharwell.bsky.social in Oct’24 to V1 of the preprint in May’25!! Take a sneak peak 👀 here: osf.io/preprints/os...
May 24, 2025 at 4:29 PM
Top quality teamwork by @cost-teatime.bsky.social repositories WG to address a key issue in maximising the impact of #Home-cageMonitoring. From the first working group meeting @mrcharwell.bsky.social in Oct’24 to V1 of the preprint in May’25!! Take a sneak peak 👀 here: osf.io/preprints/os...
Reposted by Otto
International Research Integrity Conference. I am arranging this in Sydney in November 16-18th 2025. researchintegrityconf.com Note the excellent speaker list. Contact me!
International Research Integrity Conference | 17-18 November 2025, Sydney, Australia
researchintegrityconf.com
May 14, 2025 at 3:00 AM
International Research Integrity Conference. I am arranging this in Sydney in November 16-18th 2025. researchintegrityconf.com Note the excellent speaker list. Contact me!
TIL
May 14, 2025 at 4:13 PM
TIL