Nir Drayman
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nirdrayman.bsky.social
Nir Drayman
@nirdrayman.bsky.social
Assistant professor at UCI.
Virus-host interactions in single cells (mostly HSV-1).
He / His. 🏳️‍🌈
https://draymanlab.bio.uci.edu/
Reposted by Nir Drayman
First big piece of research from our SG lab: Fadi's work with Chris Brooke's lab. Flu serially passaged 80X selects a defective genome with improved competition, but is nonviable as a full virus!
Notable improvement & safety for DVGs as antiviral RNA therapies!
www.biorxiv.org/content/10.1...
Longitudinal analysis of influenza A virus deletion-containing viral genomes reveals key determinants of co-evolutionary dynamics and interference
The substantial genetic diversity generated during influenza A virus replication facilitates both evasion of pre-existing host immunity and cross-species emergence. A major contributor to this diversi...
www.biorxiv.org
November 4, 2025 at 3:17 AM
We are searching for a lab manager!
If you are detailed oriented, like southern california, HSV-1, sequencing and microscopy, please get in touch :)
October 29, 2025 at 12:25 AM
Reposted by Nir Drayman
Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887

Please apply and/or share this post.
Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
October 17, 2025 at 11:23 PM
Reposted by Nir Drayman
I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com
Genoyer Lab
genoyerlab.com
October 3, 2025 at 6:10 PM
Reposted by Nir Drayman
UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪
careers.umass.edu/amherst/en-u...
Details - Assistant Professor - Virology | Human Resources | UMass Amherst
careers.umass.edu
October 2, 2025 at 2:51 PM
Reposted by Nir Drayman
f you’re interested in our latest developments have a look at: Comparative Systems Virology Symposium: Jens Bosse youtu.be/PlAcAR1-IJA?si… via @YouTube

Thanks to the @czbiohub for organizing and my amazing team for the great data!
Comparative Systems Virology Symposium: Jens Bosse
YouTube video by Chan Zuckerberg Biohub Network
https://youtu.be/PlAcAR1-IJA?si…
August 25, 2025 at 11:28 PM
Vincent's new paper, describing the vast heterogeneity in HSV-1 progeny production by individual human keratinocytes, is now on line! (and recieved the Editor's pick). Check it out here: journals.asm.org/doi/10.1128/...
HSV-1 progeny production by individual human keratinocytes spans three orders of magnitude | Journal of Virology
Viruses are defined by their ability to take over host cells and turn them into factories that produce new progeny. Recent advances in Biology allowed us to study viral infections at the single-cell l...
journals.asm.org
August 20, 2025 at 1:43 PM
Reposted by Nir Drayman
The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more.
recruit.ap.uci.edu/JPF09601
Junior, Assistant, or Associate Specialist – Xue Lab
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
July 17, 2025 at 8:32 PM
Reposted by Nir Drayman
In this study, led by BlueSky-less superstar undergrad Andrew Lazarus, we set out to ask whether longer reactivation events during sleep lead to more memory benefits. Results suggest this is not the case, but there are some disclaimers. Read all about it! #sleep
www.sciencedirect.com/science/arti...
Manipulating memory processing during sleep to explore the critical duration of reactivation events
Newly encoded memories are reactivated and consolidated during sleep. However, how the reactivation of a specific memory unfolds over time is poorly u…
www.sciencedirect.com
June 25, 2025 at 7:20 PM
It's a hard time to get excited about science, but still - getting ready to CRISPR ✂️✂️
June 20, 2025 at 7:10 PM
Reposted by Nir Drayman
Thank you @bwfund.bsky.social for the support! I am excited to be apart of this year’s #BWFPath cohort.
May 24, 2025 at 12:21 PM
@virulentmind.bsky.social was just announced as BW investigator! So awesome and truly well deserved. Go Megan!
May 23, 2025 at 9:37 PM
Reposted by Nir Drayman
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.

Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design

Please repost for reach 💚
May 2, 2025 at 2:39 PM
Our department is looking to hire an Associate/Full Professor in the field of Virology. Please share and apply if you are intersted. Also happy to answer any questions
recruit.ap.uci.edu/JPF09552
Associate/ Full Professor of Virology in Molecular Biology & Biochemistry
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
April 9, 2025 at 5:38 PM
Reposted by Nir Drayman
Many hundreds (perhaps up to 1000) of additional NIH grants appear to be have been terminated on Friday.

I have updated the data from the HHS TAGGS site (and converted it from a pdf to an Excel file) on the dashboard but many hundreds are still missing.

jeremymberg.github.io/jeremyberg.g...
NIH_since_1_20_25
jeremymberg.github.io
March 23, 2025 at 4:37 PM
Reposted by Nir Drayman
Tucson, Arizona today.

Original projected attendance was 3,000 people.

23,000 showed up.
March 22, 2025 at 9:10 PM
Reposted by Nir Drayman
Excited to share @joelrc.bsky.social 's new paper examining the factors underlying cell-to-cell heterogeneity in interferon induction during flu infection:

www.biorxiv.org/content/10.1...
Intrinsic OASL expression licenses interferon induction during influenza A virus infection
Effective control of viral infection requires rapid induction of the innate immune response, especially the type I and type III interferon (IFN) systems. Despite the critical role of IFN induction in ...
www.biorxiv.org
March 18, 2025 at 6:47 PM
Reposted by Nir Drayman
Is the Government Shutting Down? Here's what’s happening.

youtu.be/Vobvw7JLuEM?...
Is the Government Shutting Down? Schiff Reveals the Truth.
YouTube video by Sen. Adam Schiff
youtu.be
March 13, 2025 at 1:16 AM
Reposted by Nir Drayman
The House Continuing Resolution budget “adjustments” for NIH are drastic. Here are some examples:
March 9, 2025 at 4:11 PM
Reposted by Nir Drayman
ATTENTION: TALENT AVAILABLE

It appears that termination of SROs from institute review branches at NIH is underway (or worse).

There are also program officers and SROs who have been terminated over the past month.

IF YOU HAVE POSITIONS FOR SKILLED SCIENTIST-ADMINISTRATORS, PLEASE POST INFO HERE
a red neon sign that says help wanted on a black background .
ALT: a red neon sign that says help wanted on a black background .
media.tenor.com
March 8, 2025 at 8:54 PM
Reposted by Nir Drayman
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
February 8, 2025 at 9:21 PM
Reposted by Nir Drayman
Out now: how Herpesviruses induce and need the transcription factor DUX4, usually active only at the earliest stages of embryogenesis.

Lead by Eva/Florian from @uni-freiburg.de, with @nirdrayman.bsky.social, us from @mdc-bimsb.bsky.social and many others.

www.nature.com/articles/s41...

… (1/6)
January 27, 2025 at 4:23 PM
Going over application materials for our grad program, and came across this beauty. Anyone care to explain to the letter writer what's the issue? 😂
December 13, 2024 at 1:16 AM
Reposted by Nir Drayman
Excited for my first bluesky post announcing TWO openings for tenure track positions in virology! I am chair of the search committee and with a new department head Mike Gale we are in an exciting building phase.

Please share with anyone who might be interested: hr.myu.umn.edu/jobs/ext/365...
hr.myu.umn.edu
November 22, 2024 at 6:54 PM