Mariana Borsa
@nanaborsa.bsky.social
🇧🇷 Scientist. Cell biologist of T cells. Metabolic organelles and ageing. 🇬🇧 Wellcome Trust Fellow @University of Oxford | Simon Lab. Former SNSF and Marie Skłodowska-Curie Fellow. 🇨🇭 PhD @ETH | Oxenius Lab. She/her
https://orcid.org/0000-0003-1519-2597
https://orcid.org/0000-0003-1519-2597
Bittersweet farewell weeks at @kiroxford.bsky.social, a place pivotal to my growth as an independent scientist. With deep gratitude for this chapter, I'm thrilled to begin the next at @unibas.ch @biomedizin.unibas.ch, where my lab will study organelle inheritance in T cells in the context of ageing.
Dr Mariana Borsa (@nanaborsa.bsky.social), a postdoc studying autophagy and ageing, will leave the Kennedy Institute to start an exciting new chapter in Switzerland as a Principal Investigator!! 🎉
www.kennedy.ox.ac.uk/news/dr-mari...
www.kennedy.ox.ac.uk/news/dr-mari...
Dr Mariana Borsa to start her own research group in Basel
Dr Mariana Borsa, Postdoctoral Researcher in autophagy and ageing, will leave the Kennedy Institute to start an exciting new chapter in Switzerland as a Principal Investigator.
www.kennedy.ox.ac.uk
August 18, 2025 at 9:34 AM
Bittersweet farewell weeks at @kiroxford.bsky.social, a place pivotal to my growth as an independent scientist. With deep gratitude for this chapter, I'm thrilled to begin the next at @unibas.ch @biomedizin.unibas.ch, where my lab will study organelle inheritance in T cells in the context of ageing.
Reposted by Mariana Borsa
I've wanted to write this article for years. About my and other's struggles to even survive sometime in #academia. Thank you to the amazing editors at @plosbiology.org that gave me the forum to write this piece. #science
Too poor to science: How wealth determines who succeeds in STEM
From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...
journals.plos.org
June 24, 2025 at 6:09 PM
I've wanted to write this article for years. About my and other's struggles to even survive sometime in #academia. Thank you to the amazing editors at @plosbiology.org that gave me the forum to write this piece. #science
Reposted by Mariana Borsa
#Immunology out now @science.org
After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen.
buff.ly/49bKcTG
By Jobin, Seetharama, Rüttger et al.
After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen.
buff.ly/49bKcTG
By Jobin, Seetharama, Rüttger et al.
April 11, 2025 at 4:17 PM
#Immunology out now @science.org
After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen.
buff.ly/49bKcTG
By Jobin, Seetharama, Rüttger et al.
After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen.
buff.ly/49bKcTG
By Jobin, Seetharama, Rüttger et al.
Fantastic week in Frankfurt at the #FCQC2025. Terrific talks, inspiring science and a great opportunity to meet my mentor, colleagues and collaborators in person. Big thanks to @sfb1177.bsky.social and @dikiclab.bsky.social. Please do it again!
March 27, 2025 at 4:38 PM
Fantastic week in Frankfurt at the #FCQC2025. Terrific talks, inspiring science and a great opportunity to meet my mentor, colleagues and collaborators in person. Big thanks to @sfb1177.bsky.social and @dikiclab.bsky.social. Please do it again!
Reposted by Mariana Borsa
#InterferonFriendOrFoe?! Joe Sun, Xiaoqin Wei &co show @science.org that lung macrophage peroxisomes instruct repair programs after virus infections favoring AT2 cell renewal & recovery! IFNgamma drives pexophagy, increasing mitochondrial ROS & activating inflammasomes driving KRT8 cells & fibrosis!
Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae
Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolutio...
www.science.org
March 6, 2025 at 7:48 PM
#InterferonFriendOrFoe?! Joe Sun, Xiaoqin Wei &co show @science.org that lung macrophage peroxisomes instruct repair programs after virus infections favoring AT2 cell renewal & recovery! IFNgamma drives pexophagy, increasing mitochondrial ROS & activating inflammasomes driving KRT8 cells & fibrosis!
Reposted by Mariana Borsa
"Fundamental and applied research are both necessary for innovation in science and industry."
We're extremely proud to share the news of Annette's appointment as ETH Vice President for Research 🎉
We're extremely proud to share the news of Annette's appointment as ETH Vice President for Research 🎉
Annette Oxenius has been appointed ETH Vice President for Research. From 1 August 2025, she will assume responsibility for research development and promotion at ETH Zurich. The 56-year-old Swiss national is an esteemed immunologist and professor at the ETH Department of Biology.
Read more:
Read more:
Fundamental and applied research are two sides of the same coin
Annette Oxenius has been appointed ETH Vice President for Research. From 1 August 2025, she will assume responsibility for research development and promotion at ETH Zurich. The 56-year-old Swiss natio...
ethz.ch
March 6, 2025 at 5:07 PM
"Fundamental and applied research are both necessary for innovation in science and industry."
We're extremely proud to share the news of Annette's appointment as ETH Vice President for Research 🎉
We're extremely proud to share the news of Annette's appointment as ETH Vice President for Research 🎉
Reposted by Mariana Borsa
A study in Nature Medicine provides a comprehensive map of the contributions of environment and genetics to mortality and incidence of common age-related diseases, suggesting that the exposome shapes distinct patterns of disease and mortality risk. #Medsky 🧪
Integrating the environmental and genetic architectures of aging and mortality - Nature Medicine
Based on a systematic analysis of environmental exposures associated with aging and mortality in the UK Biobank, the relative contributions of such exposures and genetic risk for mortality and a range of age-related diseases were compared, highlighting the potential beneficial effects of environment-focused interventions.
go.nature.com
March 1, 2025 at 2:34 AM
A study in Nature Medicine provides a comprehensive map of the contributions of environment and genetics to mortality and incidence of common age-related diseases, suggesting that the exposome shapes distinct patterns of disease and mortality risk. #Medsky 🧪
Despite facing up to -20°C, spent fantastic days in my first Keystone²: exciting immunometabolism discussions and (re-)encounters with brilliant and generous leaders of the field. Happy to be part of this community #KSImmunometab25
February 13, 2025 at 10:42 PM
Despite facing up to -20°C, spent fantastic days in my first Keystone²: exciting immunometabolism discussions and (re-)encounters with brilliant and generous leaders of the field. Happy to be part of this community #KSImmunometab25
Reposted by Mariana Borsa
ICYMI by First Release - now officially in print @science.org
Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations.
https://buff.ly/4gvqKTz
From Shixin Ma, Sue Kaech @tcellogic.bsky.social et al.
#immunometabolism
Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations.
https://buff.ly/4gvqKTz
From Shixin Ma, Sue Kaech @tcellogic.bsky.social et al.
#immunometabolism
February 7, 2025 at 5:25 PM
ICYMI by First Release - now officially in print @science.org
Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations.
https://buff.ly/4gvqKTz
From Shixin Ma, Sue Kaech @tcellogic.bsky.social et al.
#immunometabolism
Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations.
https://buff.ly/4gvqKTz
From Shixin Ma, Sue Kaech @tcellogic.bsky.social et al.
#immunometabolism
Just climbed some steps to warm up for the #KSMitochondria25 in Taipei. First time in Asia, first time I will talk in a @keystonesymposia.bsky.social, all very exciting!
January 13, 2025 at 7:54 AM
Just climbed some steps to warm up for the #KSMitochondria25 in Taipei. First time in Asia, first time I will talk in a @keystonesymposia.bsky.social, all very exciting!
Reposted by Mariana Borsa
Having a color-blind colleague is a good reminder that we need to be more careful when designing figures for scientific publication 🧪
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
Color blind friendly palettes for data visualizations with categories
A discussion of color blind friendly palettes for labeling unique catergories in data visualization.
thenode.biologists.com
December 8, 2024 at 9:48 PM
Having a color-blind colleague is a good reminder that we need to be more careful when designing figures for scientific publication 🧪
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
Reposted by Mariana Borsa
After we reach advanced age, around 80, the propensity to develop cancer is markedly reduced. A discovery reported at Nature today about aged stem cells and iron insufficiency may help explain this advantage
www.nature.com/articles/d41...
www.nature.com/articles/d41...
December 4, 2024 at 6:06 PM
After we reach advanced age, around 80, the propensity to develop cancer is markedly reduced. A discovery reported at Nature today about aged stem cells and iron insufficiency may help explain this advantage
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Mariana Borsa
Immune cells change in proportions with age - naive go down, effector go up. www.science.org/doi/10.1126/...
A panoramic view of cell population dynamics in mammalian aging
To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...
www.science.org
November 29, 2024 at 8:37 AM
Immune cells change in proportions with age - naive go down, effector go up. www.science.org/doi/10.1126/...
Reposted by Mariana Borsa
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
November 25, 2024 at 12:38 PM
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
Reposted by Mariana Borsa
Cycling is 10 times more important than electric cars for reaching net-zero cities and 100 times more fun.
Cycling is ten times more important than electric cars for reaching net-zero cities
Active travel can help tackle the climate crisis earlier than electric vehicles – even if you swap the car for a bike for just one trip a day.
theconversation.com
November 23, 2024 at 8:43 PM
Cycling is 10 times more important than electric cars for reaching net-zero cities and 100 times more fun.
Reposted by Mariana Borsa
Definitely not a straightforward path, but it is happening: I am officially an Assistant Professor-to-be! 🎉 I am thrilled to announce that I was awarded a @snsf-ch.bsky.social Starting Grant and I will start my lab next year. Very grateful to all those that supported me over the last years! 🫶 (1/4)
The SNSF (@snsf-ch.bsky.social) awards Starting Grants to outstanding young researchers in Switzerland. In this year's call, five of the successful researchers plan to carry out their projects at the University of Basel.
www.unibas.ch/en/News-Even...
www.unibas.ch/en/News-Even...
SNSF awards five Starting Grants to researchers at the University of Basel
How can we age more healthily? And how can supply chains for coffee, cocoa and palm oil become more sustainable? Researchers at the University of Basel are addressing these and other questions with th...
www.unibas.ch
November 15, 2024 at 5:28 PM
Definitely not a straightforward path, but it is happening: I am officially an Assistant Professor-to-be! 🎉 I am thrilled to announce that I was awarded a @snsf-ch.bsky.social Starting Grant and I will start my lab next year. Very grateful to all those that supported me over the last years! 🫶 (1/4)
Reposted by Mariana Borsa
How do #mitochondria decide when to divide or fuse? I’ve always thought mtDNA played a key role in this process, so I was very surprised by this finding: The loss of mtDNA does not affect mitochondrial fission and fusion rates.
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/doi/10.1091/...
Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA | Molecular Biology of the Cell
Mitochondria exist as dynamic tubular networks and the morphology of these networks impacts organelle function and cell health. Mitochondrial morphology is maintained in part by the opposing activitie...
www.molbiolcell.org
November 23, 2024 at 8:37 AM
How do #mitochondria decide when to divide or fuse? I’ve always thought mtDNA played a key role in this process, so I was very surprised by this finding: The loss of mtDNA does not affect mitochondrial fission and fusion rates.
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/doi/10.1091/...
Reposted by Mariana Borsa
We’re here 🦋 ✨ and excited to build the #yEFIS network for young European #immunologists on Bluesky! #ImmunoSky
Follow us to stay updated on all our news and latest activities.
Follow us to stay updated on all our news and latest activities.
November 21, 2024 at 9:28 AM
We’re here 🦋 ✨ and excited to build the #yEFIS network for young European #immunologists on Bluesky! #ImmunoSky
Follow us to stay updated on all our news and latest activities.
Follow us to stay updated on all our news and latest activities.
Terrific scientist starting as a PI at our alma mater @ethzurich.bsky.social. Stay tuned!
Very excited to be back @ethzurich.bsky.social to build my @snsf-ch.bsky.social Ambizione group hosted by the wonderful @mucosalimmunology.bsky.social lab!
We will use advances in vivo and in vitro organoid models to dissect intestinal epithelium-microbiota crosstalk: www.annikahausmannlab.com
We will use advances in vivo and in vitro organoid models to dissect intestinal epithelium-microbiota crosstalk: www.annikahausmannlab.com
November 21, 2024 at 12:11 AM
Terrific scientist starting as a PI at our alma mater @ethzurich.bsky.social. Stay tuned!
Reposted by Mariana Borsa
We are excited to expand our platform to Bluesky! Follow @mitowomen.bsky.social for highlights on research performed by women in mitochondrial research. Check out our website for a list of outstanding women in mito research (to invite speakers, recruit students/postdocs, find collaborators, etc)
February 18, 2024 at 10:17 PM
We are excited to expand our platform to Bluesky! Follow @mitowomen.bsky.social for highlights on research performed by women in mitochondrial research. Check out our website for a list of outstanding women in mito research (to invite speakers, recruit students/postdocs, find collaborators, etc)
Reposted by Mariana Borsa
If you’re making a starter pack, take a quick look at its demographics. Worth a bit of consideration!
November 17, 2024 at 11:17 AM
If you’re making a starter pack, take a quick look at its demographics. Worth a bit of consideration!
Definitely not a straightforward path, but it is happening: I am officially an Assistant Professor-to-be! 🎉 I am thrilled to announce that I was awarded a @snsf-ch.bsky.social Starting Grant and I will start my lab next year. Very grateful to all those that supported me over the last years! 🫶 (1/4)
The SNSF (@snsf-ch.bsky.social) awards Starting Grants to outstanding young researchers in Switzerland. In this year's call, five of the successful researchers plan to carry out their projects at the University of Basel.
www.unibas.ch/en/News-Even...
www.unibas.ch/en/News-Even...
SNSF awards five Starting Grants to researchers at the University of Basel
How can we age more healthily? And how can supply chains for coffee, cocoa and palm oil become more sustainable? Researchers at the University of Basel are addressing these and other questions with th...
www.unibas.ch
November 15, 2024 at 5:28 PM
Definitely not a straightforward path, but it is happening: I am officially an Assistant Professor-to-be! 🎉 I am thrilled to announce that I was awarded a @snsf-ch.bsky.social Starting Grant and I will start my lab next year. Very grateful to all those that supported me over the last years! 🫶 (1/4)
As someone who truly missed the #science blue bird, it feels great to again tweet in a BlueSky! For those that are new here, I am a #Tcell aficionada trying to understand how diversity is imprinted by events such as #organelle inheritance. So I am slowly trying to become a cell biologist as well! 🙃
November 14, 2024 at 2:58 PM
As someone who truly missed the #science blue bird, it feels great to again tweet in a BlueSky! For those that are new here, I am a #Tcell aficionada trying to understand how diversity is imprinted by events such as #organelle inheritance. So I am slowly trying to become a cell biologist as well! 🙃