Muriel Perron
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murielperron.bsky.social
Muriel Perron
@murielperron.bsky.social
CNRS researcher interested in neural stem cells, retina, and regeneration
Reposted by Muriel Perron
🚨🚨🚨
The SFBD board needs to be renewed with 5 members
We wish to strengthen our board with young scientists

To apply: send a brief text introducing your research interests and motivations to sfbd@sfbd.fr by December 4th
Elections will be held online from December 10th to 17th
Please share the info
November 10, 2025 at 10:47 AM
Reposted by Muriel Perron
Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...
Retinal glia regulate development of the circadian photoentrainment circuit
Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…
www.sciencedirect.com
October 29, 2025 at 2:27 PM
Reposted by Muriel Perron
Ran et al. generated a retinal regeneration model and a tumor model using targeted integration in X. tropicalis (PNAS). Kagawa et al. provide a step-by-step protocol for knock-in targeted integration in X. laevis (DGD). www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
October 21, 2025 at 10:18 PM
Reposted by Muriel Perron
🔬 Limb regeneration depends on regenerative signaling center cells — but how do these cells influence others to proliferate, migrate, or differentiate?
We’re recruiting PhD or Postdoc candidates to explore this with our collaborator @osvaldo-chara.bsky.social !
October 21, 2025 at 6:56 AM
Reposted by Muriel Perron
▶️ Mark the date! On May 28-29 2026, we will host and organize the next edition of the Chen Institute Symposia: Brain, Behavior & Beyond.

▶️ This year we will focus on New Horizons in Aging and Neurodegenerative Diseases.

▶️ Stay tuned as we will soon disclose speakers and more!
October 8, 2025 at 7:14 AM
Reposted by Muriel Perron
Our latest manuscript is out, and this one tackles the problem of cellular aging in the retina, using comparative multiomic analysis of zebrafish, mouse, and humans. What led us to work on aging after studying development and regeneration? Explainer follows./1
www.biorxiv.org/content/10.1...
Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging.
Biological age is a major risk factor in the development of common degenerative retinal diseases such as age-related macular degeneration and glaucoma. To systematically characterize molecular mechani...
www.biorxiv.org
September 12, 2025 at 7:04 PM
Reposted by Muriel Perron
🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development.
We will have positions available next year. Stay tuned!
📣 The ERC Starting Grant call results are out!

Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!

➡️ buff.ly/IsafuFh

#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
September 4, 2025 at 1:27 PM
Reposted by Muriel Perron
Come be my colleague! We are hiring for two tenure-track positions. www.reed.edu/dean_of_facu...
Tenure-Track Positions in Functional Genomics/Genetics and Systems Biology - Office of the Dean of the Faculty - Reed College
www.reed.edu
August 27, 2025 at 6:43 PM
Reposted by Muriel Perron
Early embryonic developmental pathways are activated during regeneration phase in Xenopus 🐸
--by Aniket Kshirsagar, Rachel Ronan, Ana Lúcia Rebelo, Siobhan McMahon, Abhay Pandit, and Gerhard Schlosser

www.sciencedirect.com/science/arti...

#Xenopus #regeneration #DBfeature
August 9, 2025 at 1:31 PM
Reposted by Muriel Perron
My lab's newest research paper on the Drosophila eye is published in Development today. Thanks to the editorial staff for writing a research highlight and interviewing us about our work.

journals.biologists.com/dev/article-...
Differential regulation of eye specification in Drosophila by Polycomb Group epigenetic repressors
Highlighted Article: Distinct gene sets are differentially expressed in response to the knockdown of Polycomb Group (PcG) members, suggesting that multiple avenues may exist for the eye to be transfor...
journals.biologists.com
August 5, 2025 at 7:50 PM
Deadline approaching: 22 Aug 2025!!!
Tenure-track Junior Professor (CPJ) in Multi-omics Cell Atlases of Brain Development
@neuropsi.bsky.social @univparissaclay.bsky.social
Details: www.universite-paris-saclay.fr/sites/defaul...
Apply via ODYSSEE: odyssee.enseignementsup-recherche.gouv.fr
August 4, 2025 at 7:15 AM
Reposted by Muriel Perron
🔬🐁 We have a new position open!

➡️ Our "Chaire Professeur Junior" position focuses on multi-omics during brain development. This research-heavy position follows a tenure-track scheme, leading to a full professor position.

🗓️ Application deadline: 22/08/2025
www.universite-paris-saclay.fr
June 28, 2025 at 3:18 PM
Reposted by Muriel Perron
A tenure track "AI and pathological behavioral trajectories" Professor position is open at NeuroPSI.
Learn more and apply
🔽🔽🔽🔽🔽🔽
emploi.cnrs.fr/Offres/CPJ/C...
May 21, 2025 at 8:01 PM
Reposted by Muriel Perron
Join us next Monday and Tuesday (May the 19-20) for the 2025 joint TCCI/NeuroPSI conference!

This year the conference focuses on Social cognition, Decision making & Communication.

You can still register to attend online: neuropsi-2025.sciencesconf.org
May 16, 2025 at 8:29 AM
Reposted by Muriel Perron
Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
May 14, 2025 at 3:34 PM
A Tenure-track Junior Professor Chair (CPJ) is now open at @neuropsi.bsky.social
Focus: Multi-omics cellular atlases of brain development
Application details & deadline coming soon, stay tuned!
@univparissaclay.bsky.social
May 16, 2025 at 12:38 PM
Reposted by Muriel Perron
The final version of our eLife manuscript on viral Oct4-mediated neurogenic reprogramming of retinal Muller glia is now out, with all reviewer comments addressed.
elifesciences.org/reviewed-pre...
Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
elifesciences.org
April 28, 2025 at 10:07 PM
Reposted by Muriel Perron
Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1
www.biorxiv.org/content/10.1...
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...
www.biorxiv.org
April 29, 2025 at 11:06 AM
Reposted by Muriel Perron
Our latest manuscript on glia-to-neuron conversion in retina is out in @elife.bsky.social. We show that AAV-mediated overexpression of Oct4 induces glia-to-bipolar cell conversion in wildtype retina, and that this is greatly enhanced by loss of function of Rbpj.

elifesciences.org/reviewed-pre...
Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
elifesciences.org
April 5, 2025 at 2:59 PM
The Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social has launched a call for new group leaders. Please spread the word!
deadline May 30
neuropsi.cnrs.fr/wp-content/u...
@cnrs.fr @univparissaclay.bsky.social
March 18, 2025 at 7:44 AM
Reposted by Muriel Perron
Le programme de la semaine du cerveau se précise. Toute la semaine du 10 mars, NeuroPSI et NeuroSPIN vous accueillent à tour de rôle pour une série de conférences et d'animation à destination de tous les publics !
neuropsi.cnrs.fr/semaine-cerv...
February 18, 2025 at 12:40 PM
Reposted by Muriel Perron
▶️ The 2025 TCCI-NeuroPSI conference will take place on May 19-20 at NeuroPSI.

▶️ Dive with us into the dynamic interactions between social cognition, emotions and communication systems, which enable adaptive choices in complex social environments!

▶️ Register: neuropsi-2025.sciencesconf.org
February 25, 2025 at 4:58 PM
Reposted by Muriel Perron
Our new review article with @michelcayouette.bsky.social is out on temporal patterning and glial reprogramming in adult CNS, and its implications for treating degenerative diseases. All work from our lab discussed here was funded by NIH.
authors.elsevier.com/a/1kfup3Q9h2...
authors.elsevier.com
February 25, 2025 at 1:30 PM
Reposted by Muriel Perron
Happy to share this review that @sethblackshaw.bsky.social and I wrote about temporal patterning and how these mechanisms could be coaxed to stimulate glia reprogramming and CNS regeneration! Access link below, feel free to use the figures in your talks!😊
authors.elsevier.com/c/1kfup3Q9h2...
authors.elsevier.com
February 25, 2025 at 2:03 PM
Reposted by Muriel Perron
We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model. www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
February 7, 2025 at 2:35 PM