Muir Lab
@muirlab.bsky.social
Very helpful methods and protocol! www.sciexplor.com/articles/fos...
Great work @ginadenicola.bsky.social and team!
Great work @ginadenicola.bsky.social and team!
Best practices for cysteine analysis
Accurate measurement of cysteine and related thiol-containing metabolites is essential for understanding cellular redox regulation. However, the intrinsic reactivity and instability of cysteine presen...
www.sciexplor.com
February 1, 2026 at 7:24 PM
Very helpful methods and protocol! www.sciexplor.com/articles/fos...
Great work @ginadenicola.bsky.social and team!
Great work @ginadenicola.bsky.social and team!
Reposted by Muir Lab
Excited to announce that registration is officially open for #METPHYS2026!
All meeting details can be found here:
www.sablesys.com/metphys-the-...
All meeting details can be found here:
www.sablesys.com/metphys-the-...
January 13, 2026 at 4:12 PM
Excited to announce that registration is officially open for #METPHYS2026!
All meeting details can be found here:
www.sablesys.com/metphys-the-...
All meeting details can be found here:
www.sablesys.com/metphys-the-...
Reposted by Muir Lab
Join us for the 2026 NYAS Cancer Metabolism conference on March 24th at NYU Langone! The poster deadline is rapidly approaching. Speakers include @airdlab.bsky.social @bensahralab.bsky.social Javier Garcia-Bermudez, Marcus Goncalves, @naama-kanarek.bsky.social @bdmanning.bsky.social Erika Pearce,
January 9, 2026 at 6:19 PM
Join us for the 2026 NYAS Cancer Metabolism conference on March 24th at NYU Langone! The poster deadline is rapidly approaching. Speakers include @airdlab.bsky.social @bensahralab.bsky.social Javier Garcia-Bermudez, Marcus Goncalves, @naama-kanarek.bsky.social @bdmanning.bsky.social Erika Pearce,
Reposted by Muir Lab
"What the state attorney general, what the city of Chicago has done in lots of ways has been remarkable in standing up for people" Futterman said. "But one of the ways in which they've fallen short so far, one of the tools they haven't used that they have, is actually the power to arrest people."
January 8, 2026 at 11:16 PM
"What the state attorney general, what the city of Chicago has done in lots of ways has been remarkable in standing up for people" Futterman said. "But one of the ways in which they've fallen short so far, one of the tools they haven't used that they have, is actually the power to arrest people."
Reposted by Muir Lab
Another attorney representing the plaintiffs in the case, Craig Futterman with the UChicago law school, called on state and local officials to do more to hold federal agents legally accountable for their actions.
January 8, 2026 at 11:16 PM
Another attorney representing the plaintiffs in the case, Craig Futterman with the UChicago law school, called on state and local officials to do more to hold federal agents legally accountable for their actions.
Reposted by Muir Lab
Tumor-draining Lymph nodes - Online event next week!
follow the link to register
On January 13 from 11:30 – 1:00 pm ET, @thelundlab.bsky.social , Dr. Ivan Maillard, @actonlab.bsky.social , & Dr. Burkhard Ludewig will discuss lymph node remodeling in cancer:
events.cancer.gov/dcb/tdln #TLDNForums
follow the link to register
On January 13 from 11:30 – 1:00 pm ET, @thelundlab.bsky.social , Dr. Ivan Maillard, @actonlab.bsky.social , & Dr. Burkhard Ludewig will discuss lymph node remodeling in cancer:
events.cancer.gov/dcb/tdln #TLDNForums
Tumor-Draining Lymph Nodes: Gaps and Opportunities Forum Series (Overview) | Events Registration
OverviewLymph node (LN) metastasis is a hallmark of disease progression in most solid tumors and remains one of the most consistent predictors of poor prognosis and reduced overall survival. In partic...
events.cancer.gov
January 9, 2026 at 11:39 AM
Tumor-draining Lymph nodes - Online event next week!
follow the link to register
On January 13 from 11:30 – 1:00 pm ET, @thelundlab.bsky.social , Dr. Ivan Maillard, @actonlab.bsky.social , & Dr. Burkhard Ludewig will discuss lymph node remodeling in cancer:
events.cancer.gov/dcb/tdln #TLDNForums
follow the link to register
On January 13 from 11:30 – 1:00 pm ET, @thelundlab.bsky.social , Dr. Ivan Maillard, @actonlab.bsky.social , & Dr. Burkhard Ludewig will discuss lymph node remodeling in cancer:
events.cancer.gov/dcb/tdln #TLDNForums
Reposted by Muir Lab
Interested in stable isotope infusions but daunted by jugular catheter surgery? New from postdoc @kimyumi0201.bsky.social: our simple tail vein catheter method enables anesthesia-free infusions in awake, freely moving mice. 🧵
January 6, 2026 at 8:11 PM
Interested in stable isotope infusions but daunted by jugular catheter surgery? New from postdoc @kimyumi0201.bsky.social: our simple tail vein catheter method enables anesthesia-free infusions in awake, freely moving mice. 🧵
Reposted by Muir Lab
Melanoma cells that spread to lymph nodes depend on FSP1 to survive, revealing a new metabolic vulnerability. New study in Nature by @mariopalma.bsky.social @ubellackerlab.bsky.social and colleagues shows that blocking FSP1 triggers ferroptosis and suppresses tumor growth in lymph node metastases.
Lymph node environment drives FSP1 targetability in metastasizing melanoma - Nature
Targeting FSP1 in lymph nodes has considerable potential for blocking melanoma progression.
www.nature.com
November 5, 2025 at 5:28 PM
Melanoma cells that spread to lymph nodes depend on FSP1 to survive, revealing a new metabolic vulnerability. New study in Nature by @mariopalma.bsky.social @ubellackerlab.bsky.social and colleagues shows that blocking FSP1 triggers ferroptosis and suppresses tumor growth in lymph node metastases.
Reposted by Muir Lab
Excited to share our study out in @natcellbio.nature.com! Led by @mikelangelipid.bsky.social, we identify the first #LipidDroplet lipid quality control pathway: LD-localized FSP1 protects stored lipids from oxidative damage and prevents LD-initiated #ferroptosis.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis - Nature Cell Biology
Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.
www.nature.com
October 29, 2025 at 5:21 PM
Excited to share our study out in @natcellbio.nature.com! Led by @mikelangelipid.bsky.social, we identify the first #LipidDroplet lipid quality control pathway: LD-localized FSP1 protects stored lipids from oxidative damage and prevents LD-initiated #ferroptosis.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Muir Lab
Our work detailing the metabolic roles of serum for cancer cell proliferation is now out at JBC, @asbmbjournals.bsky.social!
Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process.
See here:
www.sciencedirect.com/science/arti...
Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process.
See here:
www.sciencedirect.com/science/arti...
October 13, 2025 at 8:47 PM
Our work detailing the metabolic roles of serum for cancer cell proliferation is now out at JBC, @asbmbjournals.bsky.social!
Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process.
See here:
www.sciencedirect.com/science/arti...
Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process.
See here:
www.sciencedirect.com/science/arti...
Reposted by Muir Lab
Repost! Please apply by October 15th for full consideration.
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
jobs.sciencecareers.org
October 12, 2025 at 11:50 PM
Repost! Please apply by October 15th for full consideration.
Reposted by Muir Lab
Just out in @science.org: Together with the lab of @wilhelmpalm.bsky.social, we used sequential in-vitro/in-vivo CRISPR screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
October 9, 2025 at 7:37 PM
Just out in @science.org: Together with the lab of @wilhelmpalm.bsky.social, we used sequential in-vitro/in-vivo CRISPR screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
Reposted by Muir Lab
A microneedle device for rapid dermal interstitial fluid sampling @stanforduniversity.bsky.social 🇺🇲 www.science.org/doi/10.1126/...
A microneedle device for rapid dermal interstitial fluid sampling
A device collects enough skin interstitial fluid for omics studies in just five minutes.
www.science.org
September 24, 2025 at 7:33 PM
A microneedle device for rapid dermal interstitial fluid sampling @stanforduniversity.bsky.social 🇺🇲 www.science.org/doi/10.1126/...
Super excited to share our new preprint from @cssheehan.bsky.social on how the tumor microenvironment causes drug resistance in pancreatic cancer: www.biorxiv.org/content/10.1...
Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer
Cytotoxic chemotherapy remains the standard-of-care treatment for patients with pancreatic ductal adenocarcinoma (PDAC). However, chemotherapy only has modest effects at improving patient survival due...
www.biorxiv.org
September 9, 2025 at 9:38 PM
Super excited to share our new preprint from @cssheehan.bsky.social on how the tumor microenvironment causes drug resistance in pancreatic cancer: www.biorxiv.org/content/10.1...
Reposted by Muir Lab
An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells www.nature.com/articles/s42...
An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells - Nature Metabolism
Kaluba, Rogers et al. show that in cancer cells that can metabolize ketones, they may reroute them to produce cytosolic acetyl-CoA and support tumour growth.
www.nature.com
September 8, 2025 at 11:29 AM
An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells www.nature.com/articles/s42...
Reposted by Muir Lab
I am thrilled to share that I have received an ERC Starting Grant for our project SpaceMet!
I am grateful for the ERC’s commitment to ambitious early-stage research and to KU Leuven for their support!
Stay tuned, new postdoc positions coming soon!I @erc.europa.eu @kuleuvenuniversity.bsky.social
I am grateful for the ERC’s commitment to ambitious early-stage research and to KU Leuven for their support!
Stay tuned, new postdoc positions coming soon!I @erc.europa.eu @kuleuvenuniversity.bsky.social
September 5, 2025 at 10:48 AM
I am thrilled to share that I have received an ERC Starting Grant for our project SpaceMet!
I am grateful for the ERC’s commitment to ambitious early-stage research and to KU Leuven for their support!
Stay tuned, new postdoc positions coming soon!I @erc.europa.eu @kuleuvenuniversity.bsky.social
I am grateful for the ERC’s commitment to ambitious early-stage research and to KU Leuven for their support!
Stay tuned, new postdoc positions coming soon!I @erc.europa.eu @kuleuvenuniversity.bsky.social
Reposted by Muir Lab
Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV
August 18, 2025 at 3:42 PM
Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV
Reposted by Muir Lab
🚨Preprint alert 🚨
We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants.
www.biorxiv.org/content/10.1....
pls check @olzmannlab.bsky.social
www.biorxiv.org/content/10.1...
#ferroptosis #FSP1 #antioxidants
We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants.
www.biorxiv.org/content/10.1....
pls check @olzmannlab.bsky.social
www.biorxiv.org/content/10.1...
#ferroptosis #FSP1 #antioxidants
Riboflavin metabolism shapes FSP1-driven ferroptosis resistance
Membrane protection against oxidative insults is achieved by the concerted action of glutathione peroxidase 4 (GPX4) and endogenous lipophilic antioxidants such as ubiquinone and vitamin E. Deficienci...
www.biorxiv.org
August 6, 2025 at 8:38 AM
🚨Preprint alert 🚨
We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants.
www.biorxiv.org/content/10.1....
pls check @olzmannlab.bsky.social
www.biorxiv.org/content/10.1...
#ferroptosis #FSP1 #antioxidants
We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants.
www.biorxiv.org/content/10.1....
pls check @olzmannlab.bsky.social
www.biorxiv.org/content/10.1...
#ferroptosis #FSP1 #antioxidants
Reposted by Muir Lab
Join me in Boston October 6th for a 1-day conference on #mappingbiology to transform #cancertherapeutics. Register by September 25th to benefit from the complimentary (free) admission! Topics, speakers, and talk opportunities here: abcam.me/mappingbiolo...
@abcamofficial.bsky.social
@abcamofficial.bsky.social
August 5, 2025 at 6:59 PM
Join me in Boston October 6th for a 1-day conference on #mappingbiology to transform #cancertherapeutics. Register by September 25th to benefit from the complimentary (free) admission! Topics, speakers, and talk opportunities here: abcam.me/mappingbiolo...
@abcamofficial.bsky.social
@abcamofficial.bsky.social
Reposted by Muir Lab
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
jobs.sciencecareers.org
July 21, 2025 at 7:25 PM
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Reposted by Muir Lab
Fantastic meeting 🤩🤩
thank you @olzmannlab.bsky.social and Scott Dixon for the organisation and for all the colleagues and trainees that showed up and made ut such a great event!
#ferroptosis #faseb #Ros
thank you @olzmannlab.bsky.social and Scott Dixon for the organisation and for all the colleagues and trainees that showed up and made ut such a great event!
#ferroptosis #faseb #Ros
July 31, 2025 at 9:14 PM
Fantastic meeting 🤩🤩
thank you @olzmannlab.bsky.social and Scott Dixon for the organisation and for all the colleagues and trainees that showed up and made ut such a great event!
#ferroptosis #faseb #Ros
thank you @olzmannlab.bsky.social and Scott Dixon for the organisation and for all the colleagues and trainees that showed up and made ut such a great event!
#ferroptosis #faseb #Ros
Reposted by Muir Lab
The EAAT1 aspartate/glutamate transporter is dispensable for acute myeloid leukemia cell growth and response to therapy https://www.biorxiv.org/content/10.1101/2025.07.13.664609v1
July 18, 2025 at 11:48 AM
The EAAT1 aspartate/glutamate transporter is dispensable for acute myeloid leukemia cell growth and response to therapy https://www.biorxiv.org/content/10.1101/2025.07.13.664609v1
Reposted by Muir Lab
1/ If you are in the Midwest and ❤️ metabolism, take note!
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
July 21, 2025 at 9:12 PM
1/ If you are in the Midwest and ❤️ metabolism, take note!
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
Super excited to share new review on metabolic stress and adaptations in pancreatic cancer to these stresses from @cssheehan.bsky.social
jci.org/articles/vie... 1/6
jci.org/articles/vie... 1/6
JCI -
What’s on the menu?: metabolic constraints in the pancreatic tumor microenvironment
jci.org
July 19, 2025 at 2:59 PM
Super excited to share new review on metabolic stress and adaptations in pancreatic cancer to these stresses from @cssheehan.bsky.social
jci.org/articles/vie... 1/6
jci.org/articles/vie... 1/6
Congrats to Dr. patrickjonker.bsky.social for successfully defending his thesis!
July 17, 2025 at 10:22 PM
Congrats to Dr. patrickjonker.bsky.social for successfully defending his thesis!