Gina DeNicola
@ginadenicola.bsky.social
Redox biology and cancer metabolism @ Moffitt Cancer Center. Views my own.
Exciting!
Online now! Online now! An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levels #chembiol
An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levels
Abrams et al. used circular permutation to develop a reversible FRET-based cysteine sensor. Biochemical and cell-based experiments established the sensor’s sensitivity and selectivity for cysteine. High-throughput phenotypic screens identified compounds that modulate cysteine levels, establishing the sensor as a valuable tool for studying cellular cysteine regulation.
dlvr.it
November 12, 2025 at 4:38 PM
Exciting!
The best compliment 😁
I now like metabolomics thanks to @ginadenicola.bsky.social interesting talk! Thanks for visiting MCB at Baylor College of Medicine
September 24, 2025 at 6:19 PM
The best compliment 😁
Reposted by Gina DeNicola
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
@uofunuip.bsky.social
Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
www.nature.com
August 27, 2025 at 11:05 PM
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
@uofunuip.bsky.social
Reposted by Gina DeNicola
Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details!
jobs.ruhr-uni-bochum.de/jobposting/f...
jobs.ruhr-uni-bochum.de/jobposting/f...
W1TTW2 Professorship in Membrane Biology (m/f/d)
jobs.ruhr-uni-bochum.de
August 22, 2025 at 1:47 PM
Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details!
jobs.ruhr-uni-bochum.de/jobposting/f...
jobs.ruhr-uni-bochum.de/jobposting/f...
Reposted by Gina DeNicola
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social
@dartmouthbcb.bsky.social @futurepislack.bsky.social
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
August 27, 2025 at 8:50 PM
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social
@dartmouthbcb.bsky.social @futurepislack.bsky.social
Reposted by Gina DeNicola
A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland 🇮🇪🧪
Up to 3.25 million euro in support 🤩
#GlobalTalentIreland #Research #Ireland
Up to 3.25 million euro in support 🤩
#GlobalTalentIreland #Research #Ireland
Research Ireland, on behalf of @deptoffhed.bsky.social, have launched Global Talent Ireland - a new initiative to attract exceptional mid-career and established researchers from across the globe to Ireland.
For more information visit:
www.researchireland.ie/funding/global-talent-ireland/
For more information visit:
www.researchireland.ie/funding/global-talent-ireland/
August 21, 2025 at 2:45 PM
A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland 🇮🇪🧪
Up to 3.25 million euro in support 🤩
#GlobalTalentIreland #Research #Ireland
Up to 3.25 million euro in support 🤩
#GlobalTalentIreland #Research #Ireland
Reposted by Gina DeNicola
Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...
August 18, 2025 at 7:45 AM
Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...
Reposted by Gina DeNicola
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
jobs.sciencecareers.org
July 21, 2025 at 7:25 PM
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...
Tenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cancer Center CareersTenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cance...
Working at Moffitt Cancer Center is both a career and a mission. All employees are dedicated to patient care, research and education to advance our fight against this disease.
moffitt-cancer-center-careers.hctsportals.com
August 12, 2025 at 1:11 PM
Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...
Reposted by Gina DeNicola
Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social
July 31, 2025 at 6:42 PM
Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social
Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here 🥵 but it's beautiful!
July 27, 2025 at 3:35 PM
Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here 🥵 but it's beautiful!
Reposted by Gina DeNicola
To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! ✨
Excited to share work published in @cp-cancercell.bsky.social by @yijuan.bsky.social showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed! www.sciencedirect.com/science/arti...
Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) tumors are glutamine deficient, and both tumor cells and cancer-associated fibroblasts (CAFs) rely on this ami…
www.sciencedirect.com
July 24, 2025 at 7:13 PM
To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! ✨
Reposted by Gina DeNicola
IMPORTANT IMPORTANT IMPORTANT IMPORTANT
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
Dear all, PLEASE add comments on the importance of model organism research at this link:
July 12, 2025 at 12:11 AM
IMPORTANT IMPORTANT IMPORTANT IMPORTANT
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
New work from @karrethlab.bsky.social!
FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1
June 10, 2025 at 11:55 AM
New work from @karrethlab.bsky.social!
Reposted by Gina DeNicola
FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1
June 10, 2025 at 11:49 AM
FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1
Reposted by Gina DeNicola
Great work by @rushika-perera.bsky.social!
PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer
www.nature.com/articles/s41...
Massive congratulations to @rushika-perera.bsky.social Lab!!
www.nature.com/articles/s41...
Massive congratulations to @rushika-perera.bsky.social Lab!!
PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer - Nature
PCSK9 regulates low density lipoprotein-cholesterol import and determines organ preference of metastatic pancreatic ductal adenocarcinoma, with PCSK9-low cells metastasizing to the liver and PCSK9-hig...
www.nature.com
May 21, 2025 at 5:10 PM
Great work by @rushika-perera.bsky.social!
Reposted by Gina DeNicola
REMINDER.....REMINDER......REMINDER
3 DAYS LEFT TO COMMENT ON SCHEDULE F
1/n
3 DAYS LEFT TO COMMENT ON SCHEDULE F
1/n
gumball and anais from the amazing world of gumball are sitting at a table
ALT: gumball and anais from the amazing world of gumball are sitting at a table
media.tenor.com
May 20, 2025 at 8:33 PM
REMINDER.....REMINDER......REMINDER
3 DAYS LEFT TO COMMENT ON SCHEDULE F
1/n
3 DAYS LEFT TO COMMENT ON SCHEDULE F
1/n
Reposted by Gina DeNicola
Our latest ‘Cell Scientist to Watch’ is Samantha Lewis. We caught up with Samantha to discuss her career path, the challenges for working on the ‘neglected’ mitochondrial genome and the exciting new frontiers in mitochondrial research.
journals.biologists.com/jcs/article/...
#JCSMitoSI
journals.biologists.com/jcs/article/...
#JCSMitoSI
May 20, 2025 at 2:06 PM
Our latest ‘Cell Scientist to Watch’ is Samantha Lewis. We caught up with Samantha to discuss her career path, the challenges for working on the ‘neglected’ mitochondrial genome and the exciting new frontiers in mitochondrial research.
journals.biologists.com/jcs/article/...
#JCSMitoSI
journals.biologists.com/jcs/article/...
#JCSMitoSI
So excited for this!
Abstracts are being accepted for #FOLSCR, a brand-new conference exploring a new form of cell death. With @ginadenicola.bsky.social and @brentstockwell.bsky.social, this may be one of FASEB's biggest new conferences. Submit your research by June 1 and save your space: buff.ly/HB3PDmS
May 12, 2025 at 7:35 PM
So excited for this!
MALDI imaging of lipids, metabolites and glycans all on the same section! From Ramon Sun and colleagues. www.nature.com/articles/s41...
Spatial mapping of the brain metabolome lipidome and glycome - Nature Communications
Clarke et al. presents a framework for spatial analysis of the metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging. Applying this approach, they revealed reg...
www.nature.com
May 12, 2025 at 7:34 PM
MALDI imaging of lipids, metabolites and glycans all on the same section! From Ramon Sun and colleagues. www.nature.com/articles/s41...
Reposted by Gina DeNicola
In their Tools & Resources article, Corey Cunningham @cnfxc.bsky.social Jared Rutter @rutterlab.bsky.social @uofubiochem.bsky.social & team present their dual-purification system to isolate mitochondrial subpopulations.
journals.biologists.com/jcs/article/...
#JCSMitoSI #OpenAccess #Mitochondria
journals.biologists.com/jcs/article/...
#JCSMitoSI #OpenAccess #Mitochondria
May 9, 2025 at 10:40 AM
In their Tools & Resources article, Corey Cunningham @cnfxc.bsky.social Jared Rutter @rutterlab.bsky.social @uofubiochem.bsky.social & team present their dual-purification system to isolate mitochondrial subpopulations.
journals.biologists.com/jcs/article/...
#JCSMitoSI #OpenAccess #Mitochondria
journals.biologists.com/jcs/article/...
#JCSMitoSI #OpenAccess #Mitochondria
🚨New paper alert! Led by former undergrad Amanda Sherwood @tophinogenesis.bsky.social (now PhD student at Northwestern), Amanda asked whether the glutathione or thioredoxin systems are necessary for NRF2's tumor-promoting effects in the lung. www.sciencedirect.com/science/arti...
Distinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progression
Redox regulators are emerging as critical mediators of lung tumorigenesis. NRF2 and its negative regulator KEAP1 are commonly mutated in human lung ca…
www.sciencedirect.com
May 8, 2025 at 5:33 PM
🚨New paper alert! Led by former undergrad Amanda Sherwood @tophinogenesis.bsky.social (now PhD student at Northwestern), Amanda asked whether the glutathione or thioredoxin systems are necessary for NRF2's tumor-promoting effects in the lung. www.sciencedirect.com/science/arti...
That's a wrap on the 2025 Cancer Metabolism Showcase. With everything going on it was so great to hear a fantastic career keynote from Jeff Rathmell and awesome talks and posters from students and postdocs! Hats off to @harrislab.bsky.social for running the show.
May 6, 2025 at 9:09 PM
That's a wrap on the 2025 Cancer Metabolism Showcase. With everything going on it was so great to hear a fantastic career keynote from Jeff Rathmell and awesome talks and posters from students and postdocs! Hats off to @harrislab.bsky.social for running the show.