Miguel Godinho Ferreira
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miguelgf.bsky.social
Miguel Godinho Ferreira
@miguelgf.bsky.social
Research scientist interested in #cancer and #aging. Studies the ends of #chromosomes - #telomeres 🧬 - and what happens when they get fu€&ed up💥... and all this using #zebrafish! 🐟🐟🐟

https://orcid.org/0000-0002-8363-7183
Pinned
📢 Hiring 2 Postdocs (CNRS Research Engineer) @ IRCAN (Université Côte d’Azur), Nice 🇫🇷. Spread the word, please.

Focus: intestine aging & immunity in fish 🐟
Start Nov–Dec 2025 • ~€3,175/mo

Apply:
ImmunoGUT (zebrafish) → tinyurl.com/3jx9a4ks
GUTPOWER (reef fish) → tinyurl.com/mt2ekpks
Happy and proud with our lab’s presentations at Second @frenchzebrafish.bsky.social meeting in Toulouse!
Go Fish 🇫🇷🐟!
November 1, 2025 at 7:02 PM
Reposted by Miguel Godinho Ferreira
📢 Hiring 2 Postdocs (CNRS Research Engineer) @ IRCAN (Université Côte d’Azur), Nice 🇫🇷. Spread the word, please.

Focus: intestine aging & immunity in fish 🐟
Start Nov–Dec 2025 • ~€3,175/mo

Apply:
ImmunoGUT (zebrafish) → tinyurl.com/3jx9a4ks
GUTPOWER (reef fish) → tinyurl.com/mt2ekpks
October 9, 2025 at 3:23 PM
📢 Hiring 2 Postdocs (CNRS Research Engineer) @ IRCAN (Université Côte d’Azur), Nice 🇫🇷. Spread the word, please.

Focus: intestine aging & immunity in fish 🐟
Start Nov–Dec 2025 • ~€3,175/mo

Apply:
ImmunoGUT (zebrafish) → tinyurl.com/3jx9a4ks
GUTPOWER (reef fish) → tinyurl.com/mt2ekpks
October 9, 2025 at 3:23 PM
Interested in cGAS-STING? Come and join us on 21st of October 2025 (9:30-12:30) in Nice, France!

univ-cotedazur.fr/recherche-in...
Nucleic acid sensing and innate immunity - Academy 4 Seminar Series #19 - Le Galet CHU PASTEUR NICE - October 21st, 2025 - Université Côte d'Azur
univ-cotedazur.fr
September 24, 2025 at 5:32 PM
Reposted by Miguel Godinho Ferreira
In London, hate will never win.
September 17, 2025 at 6:10 AM
Aging: “So far, no one has managed to rejuvenate anyone.” What are #telomeres? How can #zebrafish help in the study of #aging? Miguel Godinho Ferreira, a Portuguese scientist working in France, answers. Let's talk about longevity and aging.

(Portuguese only)
www.publico.pt/2025/09/16/c...
Envelhecimento: “Até agora, ninguém conseguiu rejuvenescer ninguém”
O que são os telómeros? Como pode o peixe-zebra ajudar no estudo do envelhecimento? Miguel Godinho Ferreira, cientista português a trabalhar em França, responde. Falemos então sobre a longevidade.
www.publico.pt
September 16, 2025 at 11:35 AM
Great opportunity to meet with French zebrafish community! Our lab will gladly join! Go fish! 🐟
🚨 Don’t miss it! Abstract submission closes Monday, Sept 15. frenchzebrafishmeeting.fr
Fantastic keynote speaker @KarinaYaniv and a great opportunity to connect with the @FrenchZebrafish Community. All talks will be in English. Join us! #FZM #zebrafish
2nd French Zebrafish Meeting : Abstract's submission deadline extended to September 15th 2025.
Spread the word ... Registration deadline : October 10th.
More info on www.frenchzebrafishmeeting.fr
#zebrafish #FZM2025 #scientificcommunity #biology #behavior #diseasemodels #regeneration #evolution
September 13, 2025 at 9:27 AM
It is so nice to have this trail on our recent work. Thank you, @cyrilpedia.bsky.social! The follow up is just around the corner! 🙂
'Telomere erosion is a hallmark of aging, yet its downstream mechanisms and impact on organismal aging remain unclear. This study shows that cGAS-STING inflammatory signaling drives premature aging in response to telomere shortening in #zebrafish.'

www.embopress.org/doi/full/10....
September 7, 2025 at 10:55 AM
Reposted by Miguel Godinho Ferreira
Comment in issue 17: Making sense of oxygen sensing
Glutamine sensing by mTORC1 via GCN2
Androgen signaling control via Parp7 and an ADP-ribosyl degron
Dendrite-like pseudopods let macrophages ingest bacteria
Cover by @miguelgf.bsky.social et al
www.embopress.org/toc/14602075...
September 2, 2025 at 9:37 AM
Our paper was offered the cover of The EMBO Journal. 😀
We discovered that activation of cGAS-STING causes aging in response to very short telomeres. Zebrafish deficient in telomerase and sting, reverse premature death, reduced fertility, frailty and cancer.
👉 tinyurl.com/nhd4bfb9
cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish | The EMBO Journal
imageimageTelomere erosion is a hallmark of aging, yet its downstream mechanisms and impact on organismal aging remain unclear. This study shows that cGAS-STING inflammatory signaling drives premature aging in response to telomere shortening in ...
www.embopress.org
September 1, 2025 at 9:41 AM
Not all species age the same way 😉
“We conclude that M. musculus maintains long telomeres in blood and tail throughout life”
Congrats Rhian and Dudy et al! 👏

House mouse maintains constant telomere length throughout life
url: academic.oup.com/nar/article/...
The house mouse maintains constant telomere length throughout life
Abstract. Telomeres protect the chromosome ends from deleterious DNA damage response and repair activities. In humans, telomerase maintains telomere length
academic.oup.com
August 29, 2025 at 6:48 PM
Reposted by Miguel Godinho Ferreira
What’s on at #GIMMFest Day 1 & 2? We’ll kick things off with big ideas to spark your curiosity, then dive into fresh perspectives on the future of aging and the everyday experiences that shape it.

🔗 gimm.pt/pt-pt/gimm-festival/#program
August 22, 2025 at 8:13 AM
Proud to contribute to this (Yes!) #Telomere study by Farida Djouad team. Morpholinos against zebrafish #TRF2 induce macrophage #senescence and block fin regeneration. #Parabiosis, #MacrophageTracking & #Transcriptomics show #p16-high, and low pro-inflammation.
Go Fish! 🐟🐟🐟
www.thno.org/v15p7308.htm
Disrupted macrophage metabolic adaptation and function drive senescence-induced decline in vertebrate regeneration
www.thno.org
July 19, 2025 at 10:53 AM
Reposted by Miguel Godinho Ferreira
Unlocking the Fountain of Youth ⛲: Inhibition of telomeric DNA damage response reduces premature aging in #zebrafish

#preLight prepared by Jawdat Sandakly⬇️ 👀

prelights.biologists.com/highlights/t...
Telomeric antisense oligonucleotides reduce premature aging phenotypes in telomerase mutant zebrafish - preLights
Unlocking the Fountain of Youth: Inhibition of telomeric DNA damage response reduces premature aging in zebrafish
prelights.biologists.com
June 18, 2025 at 12:46 PM
Reposted by Miguel Godinho Ferreira
Highlights work from @miguelgf.bsky.social et al. 🐟
June 18, 2025 at 1:33 PM
Thanks for the highlight, ‪@zebrafishrock.bsky.social‬! This is the first last author manuscript of Bruno Lopes-Bastos.
We are very happy for this!
Highlights work from @miguelgf.bsky.social et al. 🐟
Unlocking the Fountain of Youth ⛲: Inhibition of telomeric DNA damage response reduces premature aging in #zebrafish

#preLight prepared by Jawdat Sandakly⬇️ 👀

prelights.biologists.com/highlights/t...
June 18, 2025 at 2:58 PM
Join us in Lisbon for the GIMM Festival: #Aging and #Longevity, happening September 4–6! Explore the future of aging with 20+ invited international experts.
Secure your spot on: gimm.pt/gimm-festival/
@nataging.nature.com
June 12, 2025 at 8:01 AM
Here’s the EMBO Journal highlight on our paper!
How do shortened telomeres affect organismal health-/lifespan?
Using a zebrafish model, Miguel Godinho Ferreira @miguelgf.bsky.social and coworkers show that premature aging symptoms depend on cGAS-STING signaling
www.embopress.org/doi/full/10....
June 10, 2025 at 9:23 AM
Reposted by Miguel Godinho Ferreira
cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish | The EMBO Journal www.embopress.org/doi/full/10....
cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish | The EMBO Journal
imageimageTelomere erosion is a hallmark of aging, yet its downstream mechanisms and impact on organismal aging remain unclear. This study shows that cGAS-STING inflammatory signaling drives premature...
www.embopress.org
June 9, 2025 at 2:16 PM
It was a pleasure to invite our neighbour Corine BERTOLOTTO to IRCAN. It was a great review of the lab's work and a very nice return to Hopital Pasteur, Nice.

"Uveal melanomas: identification of new prognosis biomarkers and therapeutic targets"
June 5, 2025 at 11:59 AM
Reposted by Miguel Godinho Ferreira
“I would like to cure brain cancer. I think that's not particularly controversial.” Be that as it may, the NIH terminated that scientist's grant. Here's a huge survey of the 2,500 grants that NIH has killed or delayed...so far. Gift link: nyti.ms/43Jz1yJ
June 4, 2025 at 2:30 PM
TODAY - You are still on time for early bird registration for the GIMM Festival on #Aging and #Longevity!
Lisbon from 4–6 September 2025.
June 4, 2025 at 10:05 AM
Reposted by Miguel Godinho Ferreira
GIMM Fest | Aging and Longevity: Registrations open now! September 4-6 2025, Portugal, Lisbon. The brand new Gulbenkian Institute, launching – the very first GIMM Festival – "Aging and Longevity" to explore the future of aging through science. gimm.pt/gimm-festival/
May 29, 2025 at 9:10 AM