Marco Galardini
@mgalactus.bsky.social
Computational biologist with a taste for microbiology. Associate professor at Twincore, MHH and the RESIST excellence cluster
Wikipedia wanderer
Lab website: https://www.microbial-pangenomes-lab.org/
Wikipedia wanderer
Lab website: https://www.microbial-pangenomes-lab.org/
Sic transit gloria mundi
(yes, that's a bored ape advent calendar)
(yes, that's a bored ape advent calendar)
November 14, 2025 at 9:36 PM
Sic transit gloria mundi
(yes, that's a bored ape advent calendar)
(yes, that's a bored ape advent calendar)
We are looking to fill a position for computational PhD student, focusing on the development and application of statistical genetics methods to large collections of bacterial pathogens. Have a look at the link for more info.
RTs appreciated :)
www.microbial-pangenomes-lab.org/2025/11/06/C...
RTs appreciated :)
www.microbial-pangenomes-lab.org/2025/11/06/C...
PhD position in bacterial genomics and machine learning available
This is the official web page for the Microbial Pangenomes Lab at Twincore.
www.microbial-pangenomes-lab.org
November 13, 2025 at 10:46 AM
We are looking to fill a position for computational PhD student, focusing on the development and application of statistical genetics methods to large collections of bacterial pathogens. Have a look at the link for more info.
RTs appreciated :)
www.microbial-pangenomes-lab.org/2025/11/06/C...
RTs appreciated :)
www.microbial-pangenomes-lab.org/2025/11/06/C...
Reposted by Marco Galardini
How will population shifts affect the future burden of #AMR? 👶👩🦳 🧫
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
Combining demographic shifts with age-based resistance prevalence to estimate future antimicrobial resistance burden in Europe and implications for targets: A modelling study
Author summary Why was this study done? Infections caused by bacteria that are resistant to antibiotics are a major and growing threat to public health. Older adults and men are at higher risk of...
doi.org
November 5, 2025 at 12:06 PM
How will population shifts affect the future burden of #AMR? 👶👩🦳 🧫
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
Reposted by Marco Galardini
OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇
October 28, 2025 at 6:30 PM
OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇
Reposted by Marco Galardini
🚨 The #HIRI invites applications for 2 JUNIOR GROUP LEADER POSITIONS in the areas of:
🔵 RNA Biology
🔵 RNA Medicine
🔵 RNA Technology
Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
Find an overview in this thread. 🧵👇
(1/6)
🔵 RNA Biology
🔵 RNA Medicine
🔵 RNA Technology
Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
Find an overview in this thread. 🧵👇
(1/6)
E15 Groups
The Helmholtz Institute for RNA-based Infection Researchopens a call for
www.helmholtz-hiri.de
October 28, 2025 at 4:04 PM
🚨 The #HIRI invites applications for 2 JUNIOR GROUP LEADER POSITIONS in the areas of:
🔵 RNA Biology
🔵 RNA Medicine
🔵 RNA Technology
Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
Find an overview in this thread. 🧵👇
(1/6)
🔵 RNA Biology
🔵 RNA Medicine
🔵 RNA Technology
Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
Find an overview in this thread. 🧵👇
(1/6)
Reposted by Marco Galardini
DISCARD - The aim is to combine gene segments to create a new genome, but recombination events will cause localised or system-wide death.
October 28, 2025 at 10:28 AM
DISCARD - The aim is to combine gene segments to create a new genome, but recombination events will cause localised or system-wide death.
Reposted by Marco Galardini
🚨 A fantastic opportunity to join HIRI to start your research group on RNA Biology 👇 www.nature.com/naturecareer...
Junior Group Leader for RNA-Biology, RNA-Technology or RNA-Medicine (f/m/d) - Würzburg (Stadt), Bayern (DE) job with Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI) | 12844907
#RNAexcellence Junior Group Leader Positions (f/m/d) Job advertisement no.: 089/2025 Starting date: As soon as possible. The con...
www.nature.com
October 27, 2025 at 9:55 PM
🚨 A fantastic opportunity to join HIRI to start your research group on RNA Biology 👇 www.nature.com/naturecareer...
Reposted by Marco Galardini
The German company that makes the mechanical ladder used in the Louvre heist has used the image to advertise, with the text 'When you need to move fast'
10/10 response, no notes
10/10 response, no notes
October 24, 2025 at 8:27 AM
The German company that makes the mechanical ladder used in the Louvre heist has used the image to advertise, with the text 'When you need to move fast'
10/10 response, no notes
10/10 response, no notes
Can confirm that LLMs are still useless in unf*cking Cuda installations, which is pretty funny as that might be our best chance at containing the basilisk
October 24, 2025 at 8:25 AM
Can confirm that LLMs are still useless in unf*cking Cuda installations, which is pretty funny as that might be our best chance at containing the basilisk
Reposted by Marco Galardini
Job alert🚨📢! Join us as Director of the SIB Centre for Pathogen Bioinformatics, on a topic where global collaboration is particularly important, in a highly stimulating environment. This is a research infrastructure leadership position.
Apply or spread the word!
apply.refline.ch/499599/0346/...
Apply or spread the word!
apply.refline.ch/499599/0346/...
Director, Center for Pathogen Bioinformatics
The Centre for Pathogen Bioinformatics (CPB) is a unit of SIB which offers expertise and services in pathogen bioinformatics, computational molecular epidemiology and related multi-site project manage...
apply.refline.ch
October 23, 2025 at 5:34 AM
Job alert🚨📢! Join us as Director of the SIB Centre for Pathogen Bioinformatics, on a topic where global collaboration is particularly important, in a highly stimulating environment. This is a research infrastructure leadership position.
Apply or spread the word!
apply.refline.ch/499599/0346/...
Apply or spread the word!
apply.refline.ch/499599/0346/...
Yesterday the day finally came to open the Nintendo Labo box and try to make my daughter a hacker
youtu.be/aCAzoSAQsvY?...
youtu.be/aCAzoSAQsvY?...
Nintendo Labo First Trailer - Cardboard Toy-Cons For Nintendo Switch
YouTube video by Game Clips And Tips
youtu.be
October 20, 2025 at 6:02 AM
Yesterday the day finally came to open the Nintendo Labo box and try to make my daughter a hacker
youtu.be/aCAzoSAQsvY?...
youtu.be/aCAzoSAQsvY?...
Reposted by Marco Galardini
📢 The #HIRI is looking for a #postdoc & a #PhD student to join the research group of @jenshoer.bsky.social. His lab focuses on understanding the molecular mechanisms of #phages with #RNA genomes during infection, host takeover & anti-phage defense. 🧫🦠 More info: www.helmholtz-hiri.de/en/jobs-tale...
Working at HIRI
At the HIRI, we do not just value excellent research. Short distances, an open door policy, and a good working atmosphere—this is what distinguishes us from others. Have a look at our current job…
www.helmholtz-hiri.de
October 16, 2025 at 1:14 PM
📢 The #HIRI is looking for a #postdoc & a #PhD student to join the research group of @jenshoer.bsky.social. His lab focuses on understanding the molecular mechanisms of #phages with #RNA genomes during infection, host takeover & anti-phage defense. 🧫🦠 More info: www.helmholtz-hiri.de/en/jobs-tale...
Reposted by Marco Galardini
After a short website glitch, the applications are now open again - three #PhD opportunities; featuring (in no particular order) #Klebsiella, #protists, #biofilms, #microscopy, #bioinformatics, #mosquitoes, #midges and #microbiomes, see below!
#MicroSky #MicrobiomeSky #ProtistsOnSky #evobio 💻🧬🧪🦠🦟🔬
#MicroSky #MicrobiomeSky #ProtistsOnSky #evobio 💻🧬🧪🦠🦟🔬
October 15, 2025 at 5:38 AM
After a short website glitch, the applications are now open again - three #PhD opportunities; featuring (in no particular order) #Klebsiella, #protists, #biofilms, #microscopy, #bioinformatics, #mosquitoes, #midges and #microbiomes, see below!
#MicroSky #MicrobiomeSky #ProtistsOnSky #evobio 💻🧬🧪🦠🦟🔬
#MicroSky #MicrobiomeSky #ProtistsOnSky #evobio 💻🧬🧪🦠🦟🔬
Reposted by Marco Galardini
🌿PhD in Wildlife Health🪰Want to track zoonoses in tropical rainforests? Vet/pathology specialist, fluent in English & French?
Join us to study wildlife pathogens - linking lab & fieldwork across continents.
👉 Apply by 5 Nov 2025
www.helmholtz-hioh.de/fileadmin/HI...
@taichimpproject.bsky.social
Join us to study wildlife pathogens - linking lab & fieldwork across continents.
👉 Apply by 5 Nov 2025
www.helmholtz-hioh.de/fileadmin/HI...
@taichimpproject.bsky.social
October 14, 2025 at 11:39 AM
🌿PhD in Wildlife Health🪰Want to track zoonoses in tropical rainforests? Vet/pathology specialist, fluent in English & French?
Join us to study wildlife pathogens - linking lab & fieldwork across continents.
👉 Apply by 5 Nov 2025
www.helmholtz-hioh.de/fileadmin/HI...
@taichimpproject.bsky.social
Join us to study wildlife pathogens - linking lab & fieldwork across continents.
👉 Apply by 5 Nov 2025
www.helmholtz-hioh.de/fileadmin/HI...
@taichimpproject.bsky.social
Reposted by Marco Galardini
Last day to apply to come work with me on developing AI approaches to understanding pangenome evolution www.jobs.ac.uk/job/DOU184/p...
Postdoctoral Research Associate - Grade 7 at University of Liverpool
An opportunity for an academic position as a Postdoctoral Research Associate - Grade 7 is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
October 14, 2025 at 11:09 AM
Last day to apply to come work with me on developing AI approaches to understanding pangenome evolution www.jobs.ac.uk/job/DOU184/p...
Reposted by Marco Galardini
Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
E15 Groups
The Helmholtz Institute for RNA-based Infection Researchopens a call for
www.helmholtz-hiri.de
October 13, 2025 at 1:30 PM
Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
Reposted by Marco Galardini
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
October 8, 2025 at 9:45 PM
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
New AI term just dropped
Vibe coding is irresponsibly building software through dice rolls, not caring what code is produced
What about when engineers at the top of their game use AI tools responsibly to accelerate their work?
I propose "vibe engineering"!
simonwillison.net/2025/Oct/7/v...
What about when engineers at the top of their game use AI tools responsibly to accelerate their work?
I propose "vibe engineering"!
simonwillison.net/2025/Oct/7/v...
Vibe engineering
I feel like vibe coding is pretty well established now as covering the fast, loose and irresponsible way of building software with AI—entirely prompt-driven, and with no attention paid to …
simonwillison.net
October 8, 2025 at 7:31 PM
New AI term just dropped
Reposted by Marco Galardini
Our group has a PhD position open in this Doctoral network. Our topic is around combining proteomics AI and protein structures. Look through the website below to look at all of the projects/groups and apply.
🌟Ready to apply?
16 fully funded PhD positions are open in ProtAIomics Doctoral Network!
Join 16 labs across Europe to advance AI-powered proteomics and drive discoveries in health & biotechnology.
👉 Apply here: www.protaiomics.eu
#Proteomics #ArtificialIntelligence #MSCA #PhDOpportunities
16 fully funded PhD positions are open in ProtAIomics Doctoral Network!
Join 16 labs across Europe to advance AI-powered proteomics and drive discoveries in health & biotechnology.
👉 Apply here: www.protaiomics.eu
#Proteomics #ArtificialIntelligence #MSCA #PhDOpportunities
October 8, 2025 at 9:45 AM
Our group has a PhD position open in this Doctoral network. Our topic is around combining proteomics AI and protein structures. Look through the website below to look at all of the projects/groups and apply.
Reposted by Marco Galardini
Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon.
blog.genesmindsmachines.com/p/we-still-c...
blog.genesmindsmachines.com/p/we-still-c...
We still can’t predict much of anything in biology
Biology is hard. Yes, even for AI.
blog.genesmindsmachines.com
October 7, 2025 at 4:11 PM
Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon.
blog.genesmindsmachines.com/p/we-still-c...
blog.genesmindsmachines.com/p/we-still-c...
Nor can it automatically fetch any page from their docs
So, Claude Code won't implement almost anything using openAI's API, stopping with a generic error 💯
October 7, 2025 at 5:35 PM
Nor can it automatically fetch any page from their docs
Reposted by Marco Galardini
After being with the journal since its very inception, the time has come for me to step back from Microbial Genomics. This is a wonderful opportunity to have a leadership role in one of the leading journals for microbial genomics research
microbiologysociety.org/news/society...
microbiologysociety.org/news/society...
<i>Microbial Genomics </i> Deputy Editor-in-Chief: Call for Expressions of interest
microbiologysociety.org
October 7, 2025 at 8:44 AM
After being with the journal since its very inception, the time has come for me to step back from Microbial Genomics. This is a wonderful opportunity to have a leadership role in one of the leading journals for microbial genomics research
microbiologysociety.org/news/society...
microbiologysociety.org/news/society...
So, Claude Code won't implement almost anything using openAI's API, stopping with a generic error 💯
October 5, 2025 at 5:15 PM
So, Claude Code won't implement almost anything using openAI's API, stopping with a generic error 💯
Reposted by Marco Galardini
On Wednesday I started my postdoc at the Institut für Infektionskrankheiten (IFIK) @unibe.ch 🧬💻 Excited to get started on my project exploring Streptococcus pneumoniae virulence and all the science ahead!
October 3, 2025 at 8:34 AM
On Wednesday I started my postdoc at the Institut für Infektionskrankheiten (IFIK) @unibe.ch 🧬💻 Excited to get started on my project exploring Streptococcus pneumoniae virulence and all the science ahead!
Reposted by Marco Galardini
Precisely calling mutations across hundreds of bacterial isolates has been hard, requiring manual filtering and expertise.
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV
Accurate detection of mutations within bacterial species is critical for fundamental studies of microbial evolution, reconstructing transmission events, and identifying antimicrobial resistance mutati...
www.biorxiv.org
September 29, 2025 at 7:45 PM
Precisely calling mutations across hundreds of bacterial isolates has been hard, requiring manual filtering and expertise.
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...