Mike Schmidt
@mfs.ms
Neuroscientist, curious about math, fMRI, psychiatry, moods, and individual differences.
Reposted by Mike Schmidt
This one hit me in the feels today
June 29, 2025 at 8:30 PM
This one hit me in the feels today
Reposted by Mike Schmidt
"Machine vision systems—which have neither bodily states nor conscious thoughts—can predict with remarkable accuracy how humans will feel about the things they look at." 👀🔥
The perceptual primacy of feeling (PNAS Jan 2025) www.pnas.org/doi/10.1073/...
#neuroskyence #vision #affectsci
The perceptual primacy of feeling (PNAS Jan 2025) www.pnas.org/doi/10.1073/...
#neuroskyence #vision #affectsci
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
May 21, 2025 at 6:48 AM
"Machine vision systems—which have neither bodily states nor conscious thoughts—can predict with remarkable accuracy how humans will feel about the things they look at." 👀🔥
The perceptual primacy of feeling (PNAS Jan 2025) www.pnas.org/doi/10.1073/...
#neuroskyence #vision #affectsci
The perceptual primacy of feeling (PNAS Jan 2025) www.pnas.org/doi/10.1073/...
#neuroskyence #vision #affectsci
Reposted by Mike Schmidt
What's it like at some agencies right now? I'm fresh off a conference where I got to speak to a bunch of people still at some important agencies. What's the climate like? Why are you staying? Generally the responses felt like this, and we are all Maggie:
May 12, 2025 at 8:14 PM
What's it like at some agencies right now? I'm fresh off a conference where I got to speak to a bunch of people still at some important agencies. What's the climate like? Why are you staying? Generally the responses felt like this, and we are all Maggie:
Reposted by Mike Schmidt
All of our neural dynamics tools, software, protocols, datasets, and even hardware plans are now available in one convenient place!
Check it out and let us know what you'd like to see next: www.allenneuraldynamics.org/tools
🧠📈
Check it out and let us know what you'd like to see next: www.allenneuraldynamics.org/tools
🧠📈
Open Tools | Allen Institute for Neural Dynamics
We are doing science in the open. Our data and tools are openly available to the community.
www.allenneuraldynamics.org
May 5, 2025 at 11:48 PM
All of our neural dynamics tools, software, protocols, datasets, and even hardware plans are now available in one convenient place!
Check it out and let us know what you'd like to see next: www.allenneuraldynamics.org/tools
🧠📈
Check it out and let us know what you'd like to see next: www.allenneuraldynamics.org/tools
🧠📈
There's also doi.org/10.1038/s442..., where ketamine vs placebo was masked by anesthesia during surgery, so there shouldn't be any placebo effect. But it was "surprisingly high" anyway. They've reanalyzed the data to look at the opioid system as a cause in doi.org/10.1016/j.ja....
Randomized trial of ketamine masked by surgical anesthesia in patients with depression - Nature Mental Health
In this clinical trial, a single dose of intravenous ketamine delivered during surgical anesthesia had no greater effect than placebo in acutely reducing the severity of depressive symptoms in adults ...
doi.org
May 6, 2025 at 2:00 PM
There's also doi.org/10.1038/s442..., where ketamine vs placebo was masked by anesthesia during surgery, so there shouldn't be any placebo effect. But it was "surprisingly high" anyway. They've reanalyzed the data to look at the opioid system as a cause in doi.org/10.1016/j.ja....
So very excited [these](www.foundationalpapersincomplexityscience.org) arrived today!! I doubt I'll ever get through them all, but I always get inspiration and ambition from the complex systems perspective.
May 3, 2025 at 11:05 PM
So very excited [these](www.foundationalpapersincomplexityscience.org) arrived today!! I doubt I'll ever get through them all, but I always get inspiration and ambition from the complex systems perspective.
I found joy today,
not cold, but slightly chilled,
emerging from the shade into the warm sunshine.
not cold, but slightly chilled,
emerging from the shade into the warm sunshine.
April 27, 2025 at 2:50 AM
I found joy today,
not cold, but slightly chilled,
emerging from the shade into the warm sunshine.
not cold, but slightly chilled,
emerging from the shade into the warm sunshine.
Reposted by Mike Schmidt
Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.
April 15, 2025 at 3:52 AM
Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.
Reposted by Mike Schmidt
Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
March 22, 2025 at 12:19 AM
Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
Reposted by Mike Schmidt
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
Reposted by Mike Schmidt
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.
Learn more in this week's issue: scim.ag/3FA3Ygq
Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 6:05 PM
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.
Learn more in this week's issue: scim.ag/3FA3Ygq
Learn more in this week's issue: scim.ag/3FA3Ygq
Reposted by Mike Schmidt
I think we have enough evidence to now argue that AI is not getting exponentially better, or even linearly better. It is asymptotically converging on a level of inadequacy, and even that is only happening because the data thieves are still stealing everything that isn’t nailed down.
I’ve lost patience with the claims that (a) AI will somehow get better (b) there are patterns of use that are genuinely useful. Maybe so, but those are not what I’m seeing.
And the cheerleaders who tell my students that AIs are the future are, I think, morally culpable.
And the cheerleaders who tell my students that AIs are the future are, I think, morally culpable.
March 21, 2025 at 12:32 PM
I think we have enough evidence to now argue that AI is not getting exponentially better, or even linearly better. It is asymptotically converging on a level of inadequacy, and even that is only happening because the data thieves are still stealing everything that isn’t nailed down.
Reposted by Mike Schmidt
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.
March 11, 2025 at 3:17 PM
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.
Reposted by Mike Schmidt
Have not been able to tear myself away from exploring these just received spatial transcriptomics data from the septum and surrounding nuclei in human 🧠. Fascinating to explore since there are no comprehensive spatial gene expression data across these regions yet available in human brain.
March 1, 2025 at 3:01 PM
Have not been able to tear myself away from exploring these just received spatial transcriptomics data from the septum and surrounding nuclei in human 🧠. Fascinating to explore since there are no comprehensive spatial gene expression data across these regions yet available in human brain.
Reposted by Mike Schmidt
I currently have two fully-funded PhD opportunities in my lab - both providing a chance to work on the incredible LEAF data set that we have been collecting the last couple of years (220 children followed longitudinally from 10-30 months on measures of attention and early EF). Please share!
March 1, 2025 at 1:02 PM
I currently have two fully-funded PhD opportunities in my lab - both providing a chance to work on the incredible LEAF data set that we have been collecting the last couple of years (220 children followed longitudinally from 10-30 months on measures of attention and early EF). Please share!
Reposted by Mike Schmidt
RFK Jr. Vows To Make Measles Deaths So Common They Won’t Be Upsetting Anymore
RFK Jr. Vows To Make Measles Deaths So Common They Won’t Be Upsetting Anymore
WASHINGTON—Addressing the ongoing outbreak in Texas that has infected at least 124 state residents and killed one child, Health and Human Services Secretary Robert F. Kennedy Jr. vowed Thursday to mak...
theonion.com
February 27, 2025 at 8:00 PM
RFK Jr. Vows To Make Measles Deaths So Common They Won’t Be Upsetting Anymore
Reposted by Mike Schmidt
Now accepted at Nature Computational Science:
Nicole shows how #Bayesian #hierarchical #models can explicitly model major #source of #population #stratification in 10,000 ABCD subjects.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Nicole shows how #Bayesian #hierarchical #models can explicitly model major #source of #population #stratification in 10,000 ABCD subjects.
pmc.ncbi.nlm.nih.gov/articles/PMC...
January 28, 2025 at 7:15 PM
Now accepted at Nature Computational Science:
Nicole shows how #Bayesian #hierarchical #models can explicitly model major #source of #population #stratification in 10,000 ABCD subjects.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Nicole shows how #Bayesian #hierarchical #models can explicitly model major #source of #population #stratification in 10,000 ABCD subjects.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted by Mike Schmidt
This looks like amazing new work from my colleagues at Stanford demonstrating the opponent interactions of DA and 5HT in reinforcement learning.
Opponent control of reinforcement by striatal dopamine and serotonin - Nature
Nature - Opponent control of reinforcement by striatal dopamine and serotonin
www.nature.com
January 2, 2025 at 3:44 PM
This looks like amazing new work from my colleagues at Stanford demonstrating the opponent interactions of DA and 5HT in reinforcement learning.
Reposted by Mike Schmidt
𝗗𝘆𝗻𝗮𝗺𝗶𝗰𝗮𝗹 𝘁𝗵𝗲𝗼𝗿𝘆 𝗼𝗳 𝗰𝗼𝗺𝗽𝗹𝗲𝘅 𝘀𝘆𝘀𝘁𝗲𝗺𝘀 𝘄𝗶𝘁𝗵 𝘁𝘄𝗼-𝘄𝗮𝘆
𝗺𝗶𝗰𝗿𝗼–𝗺𝗮𝗰𝗿𝗼 𝗰𝗮𝘂𝘀𝗮𝘁𝗶𝗼𝗻
Interesting paper but top-down causation seems to be way of capturing how micro-level entities respond to *aggregate state* of all other micro-level entities
#complexity
ht @evanthompson.bsky.social
www.pnas.org/doi/10.1073/...
𝗺𝗶𝗰𝗿𝗼–𝗺𝗮𝗰𝗿𝗼 𝗰𝗮𝘂𝘀𝗮𝘁𝗶𝗼𝗻
Interesting paper but top-down causation seems to be way of capturing how micro-level entities respond to *aggregate state* of all other micro-level entities
#complexity
ht @evanthompson.bsky.social
www.pnas.org/doi/10.1073/...
December 14, 2024 at 7:39 PM
𝗗𝘆𝗻𝗮𝗺𝗶𝗰𝗮𝗹 𝘁𝗵𝗲𝗼𝗿𝘆 𝗼𝗳 𝗰𝗼𝗺𝗽𝗹𝗲𝘅 𝘀𝘆𝘀𝘁𝗲𝗺𝘀 𝘄𝗶𝘁𝗵 𝘁𝘄𝗼-𝘄𝗮𝘆
𝗺𝗶𝗰𝗿𝗼–𝗺𝗮𝗰𝗿𝗼 𝗰𝗮𝘂𝘀𝗮𝘁𝗶𝗼𝗻
Interesting paper but top-down causation seems to be way of capturing how micro-level entities respond to *aggregate state* of all other micro-level entities
#complexity
ht @evanthompson.bsky.social
www.pnas.org/doi/10.1073/...
𝗺𝗶𝗰𝗿𝗼–𝗺𝗮𝗰𝗿𝗼 𝗰𝗮𝘂𝘀𝗮𝘁𝗶𝗼𝗻
Interesting paper but top-down causation seems to be way of capturing how micro-level entities respond to *aggregate state* of all other micro-level entities
#complexity
ht @evanthompson.bsky.social
www.pnas.org/doi/10.1073/...
Reposted by Mike Schmidt
💯
Hallucination is totally the wrong word, implying it is perceiving the world incorrectly.
But it's generating false, plausible sounding statements. Confabulation is literally the perfect word.
So, let's all please start referring to any junk that an LLM makes up as "confabulations".
Hallucination is totally the wrong word, implying it is perceiving the world incorrectly.
But it's generating false, plausible sounding statements. Confabulation is literally the perfect word.
So, let's all please start referring to any junk that an LLM makes up as "confabulations".
petition to change the word describing ChatGPT's mistakes from 'hallucinations' to 'confabulations'
A hallucination is a false subjective sensory experience. ChatGPT doesn't have experiences!
It's just making up plausible-sounding bs, covering knowledge gaps. That's confabulation
A hallucination is a false subjective sensory experience. ChatGPT doesn't have experiences!
It's just making up plausible-sounding bs, covering knowledge gaps. That's confabulation
December 11, 2024 at 2:47 PM
💯
Hallucination is totally the wrong word, implying it is perceiving the world incorrectly.
But it's generating false, plausible sounding statements. Confabulation is literally the perfect word.
So, let's all please start referring to any junk that an LLM makes up as "confabulations".
Hallucination is totally the wrong word, implying it is perceiving the world incorrectly.
But it's generating false, plausible sounding statements. Confabulation is literally the perfect word.
So, let's all please start referring to any junk that an LLM makes up as "confabulations".
I need this!! Now, how highly should I prioritize reading this paper, and which to-do list should I put it on?
December 10, 2024 at 4:36 PM
I need this!! Now, how highly should I prioritize reading this paper, and which to-do list should I put it on?
Try the sites listed at www.sci-hub.pub, but before you do, learn about the context at en.wikipedia.org/wiki/Sci-Hub to determine your comfort level with the legality of "stealing" publications your tax dollars funded.
December 10, 2024 at 2:44 AM
Try the sites listed at www.sci-hub.pub, but before you do, learn about the context at en.wikipedia.org/wiki/Sci-Hub to determine your comfort level with the legality of "stealing" publications your tax dollars funded.
Reposted by Mike Schmidt
🚨New WP🚨
We examine news sharing on 7 platforms:
1)Right-leaning platforms=lower quality news
2)Echo-platforms: Right-leaning news gets more engagement on right-leaning platforms, vice-versa for left-leaning
3)But low-quality news gets more engagement EVERYWHERE, even BlueSky!
osf.io/preprints/ps...
We examine news sharing on 7 platforms:
1)Right-leaning platforms=lower quality news
2)Echo-platforms: Right-leaning news gets more engagement on right-leaning platforms, vice-versa for left-leaning
3)But low-quality news gets more engagement EVERYWHERE, even BlueSky!
osf.io/preprints/ps...
December 9, 2024 at 7:48 PM
🚨New WP🚨
We examine news sharing on 7 platforms:
1)Right-leaning platforms=lower quality news
2)Echo-platforms: Right-leaning news gets more engagement on right-leaning platforms, vice-versa for left-leaning
3)But low-quality news gets more engagement EVERYWHERE, even BlueSky!
osf.io/preprints/ps...
We examine news sharing on 7 platforms:
1)Right-leaning platforms=lower quality news
2)Echo-platforms: Right-leaning news gets more engagement on right-leaning platforms, vice-versa for left-leaning
3)But low-quality news gets more engagement EVERYWHERE, even BlueSky!
osf.io/preprints/ps...
I finally got a chance to watch that talk last night, and I agree it was excellent. We've been debating different regression schemes for training similar classifiers for a long time and this discussion was helpful. Thanks for sharing, Deon!
December 9, 2024 at 5:08 PM
I finally got a chance to watch that talk last night, and I agree it was excellent. We've been debating different regression schemes for training similar classifiers for a long time and this discussion was helpful. Thanks for sharing, Deon!