Matthias Flotho
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mflot.bsky.social
Matthias Flotho
@mflot.bsky.social
PhD candidate at Helmholtz Institute for Pharmaceutical Research Saarland
Pinned
Reposted by Matthias Flotho
The Hektoria Glacier on the Antarctic Peninsula retreated by at least 8 km in two months, a rate nearly 10 times faster than previously measured for a grounded glacier, according to a study in Nature Geoscience. go.nature.com/4nETBYJ ⚒️ 🧪
November 13, 2025 at 2:29 AM
Reposted by Matthias Flotho
piRNA-directed DNA methylation may not be a mammalian invention, but can already be found in the germline of axolotl salamanders
Donal O’Carroll and coworkers
www.embopress.org/doi/full/10....
November 13, 2025 at 11:54 AM
November 3, 2025 at 4:22 PM
October 27, 2025 at 2:18 PM
Reposted by Matthias Flotho
See how the U.S. got hooked on ultraprocessed foods, one of the greatest health threats of our time.
How America Got Hooked on Ultraprocessed Foods
They promised convenience and cheap nutrition. But they became one of the greatest health threats of our time.
nyti.ms
October 25, 2025 at 8:57 PM
Reposted by Matthias Flotho
Droht durch die Einigung im Zollstreit der EU mit den USA eine Schwächung von EU-Fahrzeugstandards? 😟🚗🌍
Das befürchten zahlreiche europäische Städte und zivile Organisationen in einem Brief an die EU!
Accepting US car standards would risk European lives, warn cities and civil society
Opening the EU market to vehicles certified under US standards would weaken the protections that save lives in Europe, say more than 80 civil society organisations and the administrations of…
etsc.eu
October 22, 2025 at 5:01 PM
Fucking awesome work!
"Hand-curated by three months"(the author)

doi.org/10.1093/nar/...

#openscience
SmallBARNA 2026: a kingdom-wide bacterial sRNA resource
Abstract. Bacterial small RNA are important context-sensitive regulators of gene expression, especially in highly pathogenic bacteria, often controlling vi
doi.org
October 22, 2025 at 9:00 AM
Reposted by Matthias Flotho
MCPmed is live🎉 Make biomedical APIs, and databases LLM-ready via the Model Context Protocol (MCP)!

- MCPmed Templates: wrap APIs fast
- Breadcrumbs: drop LLM-readable tags in your web service

More projects online now. Star & follow: github.com/MCPmed #LLM #Bioinformatics #OpenScience
MCPmed
MCPmed has 6 repositories available. Follow their code on GitHub.
github.com
July 14, 2025 at 6:26 PM
Reposted by Matthias Flotho
😱 “A researcher recalled wondering about the level of 6 LIN tanks used to maintain samples “going back to the 80s” and checked on them to find that “all of them were bone dry. Then they checked with their business office and learned that “our lab hadn’t purchased any liquid nitrogen since 2016.”
Exclusive: How a researcher faked data and gaslit a labmate for years
Ryan Evanoff Sometime in early 2019, a postdoc in a veterinary microbiology lab at Washington State University (WSU) in Pullman came to suspect that a research assistant in her lab was fabricating …
retractionwatch.com
September 6, 2025 at 10:58 AM
Reposted by Matthias Flotho
www.ingentaconnect.com/content/wfbi...
In our new paper we have described several new species of Hypoxylaceae and found that the genus Rostrohypoxylon is obsolete because it is nested in Annulohypoxylon in the multi-locus phylogeny. Secondary metabolite profiles of all taxa are also reported.
September 6, 2025 at 6:01 AM
Reposted by Matthias Flotho
Angiopoietin signalling is a central axis of amyloid-driven vascular dysfunction in Alzheimer's disease https://www.biorxiv.org/content/10.1101/2025.08.25.672093v1
August 29, 2025 at 2:15 PM
Reposted by Matthias Flotho
Angiopoietin signalling is a central axis of amyloid-driven vascular dysfunction in Alzheimer's disease https://www.biorxiv.org/content/10.1101/2025.08.25.672093v1
August 29, 2025 at 2:15 PM
Reposted by Matthias Flotho
Making Your Research Free May Cost You
* With federal funding exceptionally unreliable, scientists say they are stressed about spending thousands of grant dollars on unexpected and questionable open-access charges.
By @stephaniemlee.bsky.social for @chronicle.com
www.chronicle.com/article/maki...
Making Your Research Free May Cost You
Under a new requirement that NIH-funded research be freely, immediately available, some journals are forcing researchers to pay to publish.
www.chronicle.com
August 29, 2025 at 4:54 PM
Reposted by Matthias Flotho
Exercise can reduce pain, but you don’t have to work out harder to feel the benefit.

New research suggests that fitness level and sex may play a bigger role than exercise intensity in how we experience exercise-induced pain relief.
Painkiller exercise
High-intensity exercise relieves pain more than low-intensity activity – but only in males with high fitness levels.
buff.ly
August 29, 2025 at 8:02 PM
Reposted by Matthias Flotho
If you want to try it out, the plugin can be installed from pip:

pip install napari[all] napari-pyflowreg

and allows motion correction as well as basic motion analysis and visualization functionality.

#napari #2P #microscopy #neuroimaging #motioncorrection
Just released: PyFlowReg and napari-FlowReg are now online and on pip.
Python bindings and a Napari plugin for Flow-Registration – variational optical-flow motion correction for 2-photon microscopy.

github.com/FlowRegSuite
#pip #openscience #2PImaging
August 22, 2025 at 8:46 AM
Just released: PyFlowReg and napari-FlowReg are now online and on pip.
Python bindings and a Napari plugin for Flow-Registration – variational optical-flow motion correction for 2-photon microscopy.

github.com/FlowRegSuite
#pip #openscience #2PImaging
August 22, 2025 at 8:39 AM
Reposted by Matthias Flotho
This is the definition of a failed social media platform.
August 20, 2025 at 1:41 PM
Reposted by Matthias Flotho
ROSMAP-Compass: A data-harmonised, AI-ready atlas of 22 million single nuclei from the ROSMAP cohort #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.08.11.668964v1
August 15, 2025 at 7:02 AM