The Leibniz-Institut für Analytische Wissenschaften - ISAS - e. V. develops efficient analytical methods for health research. Thus, it contributes to the improvement of the prevention, early diagnosis, and therapy of diseases like cardiovascular diseases or cancer. Overall, the institute strives to advance precision medicine by combining knowledge from different fields such as biology, chemistry, computer science, medicine, pharmacology, and physics. ISAS is a member of the Leibniz Association and is publicly funded by the Federal Republic of Germany and its federal states.

Scientific Reports - Fecal transplantation from humans with obesity to mice drives a selective microbial signature without impacting behavioral and metabolic health

Researchers found that higher urinary levels of caffeine and specific metabolites, especially in men, were significantly associated with diabetic retinopathy risk. The cross-sectional study used NHANE...

Background and Aims Alcohol-related liver disease (ALD) is a major cause of mortality and disability-adjusted life years. It is not fully understood why a small proportion of patients develop progre...

Metabolic profiling of Iron Age residues from the oasis of Qurayyah, Northwest Arabia, reveals the earliest material evidence for the fumigation of the drug plant Peganum harmala, used in domestic con...

Abstract. Microfluidic capillary electrophoresis-mass spectrometry (CE-MS) is a rapid and highly accurate method to determine isotopomer patterns in isotop

De Graeve et al., (2025). SpectriPy: Enhancing Cross-Language Mass Spectrometry Data Analysis with R and Python. Journal of Open Source Software, 10(109), 8070, https://doi.org/10.21105/joss.08070

Imperial College London is a world-leading university for science, technology, engineering, medicine and business (STEMB). Across our London campuses, and throughout our international network, we use ...

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Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose t...