Lesley Goodburn
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lgoodbu.bsky.social
Lesley Goodburn
@lgoodbu.bsky.social
1.3K followers 2.6K following 2.7K posts
Sharing Seth's Story - A film, a play and educational resource to improve end of life care, raise awareness of pancreatic cancer signs and symptoms - views are my own #sethslegacy
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lgoodbu.bsky.social
When I was diagnosed with lobular breast cancer in Dec 2024 I knew I would face a difficult 2025 so I purchased a line a day five year journal and every day last year I filled it in in 2026 I plan to share a month by month summary of my journey #lobularlineaday
January 25, 2026 at 6:09 PM
lgoodbu.bsky.social
The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer url: aacrjournals.org/cancerres/ar...
The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer
AbstractAging is a critical yet understudied determinant in pancreatic ductal adenocarcinoma (PDAC) risk and outcomes. Despite a strong epidemiologic association with age, conventional PDAC preclinica...
aacrjournals.org
January 23, 2026 at 9:50 PM
lgoodbu.bsky.social
IU researcher identifies biomarkers that could improve early detection of pancreatic cancer | EurekAlert! www.eurekalert.org/news-release...
IU researcher identifies biomarkers that could improve early detection of pancreatic cancer
Jianjun Zhang has identified a set of novel biomarkers that could significantly improve early detection of pancreatic cancer, a disease with a five-year survival rate of just 13%, the lowest among maj...
www.eurekalert.org
January 23, 2026 at 9:23 PM
lgoodbu.bsky.social
IU researcher identifies biomarkers that could improve early detection of pancreatic cancer | EurekAlert! www.eurekalert.org/news-release...
IU researcher identifies biomarkers that could improve early detection of pancreatic cancer
Jianjun Zhang has identified a set of novel biomarkers that could significantly improve early detection of pancreatic cancer, a disease with a five-year survival rate of just 13%, the lowest among maj...
www.eurekalert.org
January 23, 2026 at 9:22 PM
lgoodbu.bsky.social
Selective targeting of NRF2-high pancreatic ductal adenocarcinoma with an NQO1-activatable prodrug | PNAS www.pnas.org/doi/abs/10.1...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
January 23, 2026 at 9:18 PM
lgoodbu.bsky.social
Fabulous it’s such a great opportunity to raise much needed funds and awareness and what a fab prize
January 21, 2026 at 9:40 AM
Reposted by Lesley Goodburn
surgeryhpb.bsky.social
I’ve bought my tickets! Help Pancreatic Cancer UK and buy yours!
January 21, 2026 at 9:18 AM
lgoodbu.bsky.social
www.news-medical.net/news/2026012...
Atypical mutation offers clues to personalized pancreatic cancer treatment
A new study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants.
www.news-medical.net
January 21, 2026 at 7:53 AM
lgoodbu.bsky.social
oncodaily.com/voices/anirb...
Anirban Maitra: Retrospective Study Highlights Prognosis in Lung-Only vs Other Metastatic Pancreatic Cancer - OncoDaily
Anirban Maitra: Retrospective Study Highlights Prognosis in Lung-Only vs Other Metastatic Pancreatic Cancer / Alice Boilève, Alina Fuerea, Anirban Maitra,
oncodaily.com
January 20, 2026 at 9:56 PM
lgoodbu.bsky.social
www.targetedonc.com/view/zenocut...
Zenocutuzumab Offers Durable Benefit After Progression in NRG1+ GI Tumors | Targeted Oncology - Immunotherapy, Biomarkers, and Cancer Pathways
Zenocutuzumab shows promising efficacy in advanced NRG1+ pancreatic and cholangiocarcinoma, offering hope for patients after disease progression.
www.targetedonc.com
January 20, 2026 at 9:55 PM
lgoodbu.bsky.social
oncodaily.com/dialogues/on...
Philip A. Philip on Pancreatic Cancer at ASCO GI 2026
Philip A. Philip discusses current pancreatic cancer care and global mentorship in this ASCO GI 2026 interview.
oncodaily.com
January 20, 2026 at 9:55 PM
lgoodbu.bsky.social
finance.yahoo.com/news/fite-co...
Can-Fite Completes Patient Enrollment in Phase 2a Pancreatic Cancer Study of Namodenoson
Primary Safety Endpoint Demonstrated to Date; Top-Line Efficacy Data Expected in Q3 2026 Ramat Gan, Israel, Jan. 20, 2026 (GLOBE NEWSWIRE) -- Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF)...
finance.yahoo.com
January 20, 2026 at 9:54 PM
lgoodbu.bsky.social
www.nature.com/articles/s41...
Disruption of iron homeostasis sensitizes pancreatic cancer to irreversible electroporation - Nature Communications
Irreversible electroporation (IRE) is a treatment for pancreatic cancer, but its efficacy is limited by uneven electric field distribution. Here, the authors show that combining iron-based nanoparticl...
www.nature.com
January 20, 2026 at 9:53 PM
lgoodbu.bsky.social
www.cancernetwork.com/view/multian...
Multiantigen-Targeted T Cells Safe/Feasible in Locally Advanced PDAC | CancerNetwork
Patients with pancreatic cancer who received up to 6 infusions of the multiantigen-targeted T cell product only experienced 1 treatment-related serious AE.
www.cancernetwork.com
January 20, 2026 at 9:52 PM
lgoodbu.bsky.social
medicalxpress.com/news/2026-01...
Unusual KRAS mutation in pancreatic cancer may explain less aggressive tumors
A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants.
medicalxpress.com
January 20, 2026 at 9:51 PM
lgoodbu.bsky.social
Hollings researchers reveal why some pancreatic tumors behave differently | EurekAlert! www.eurekalert.org/news-release...
Hollings researchers reveal why some pancreatic tumors behave differently
A new study led by MUSC Hollings Cancer Center researchers Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., sheds light on why pancreatic tumors with the KRAS G12R mutation behave less aggressively t...
www.eurekalert.org
January 20, 2026 at 9:50 PM
lgoodbu.bsky.social
people.com/breast-cance...
How Her Own Breast Cancer Diagnosis Changed How This Breast Cancer Doctor Treats Patients: 'Now I'm in it'
A Breast Cancer Expert Was Diagnosed With Breast Cancer: Now She Helps Patients Nationwide
people.com
January 20, 2026 at 9:48 PM
lgoodbu.bsky.social
www.thepharmacist.co.uk/clinical/nut...
The serious shortage protocol for Creon has been extended
The Serious Shortage Protocol (SSP) for pancreatic enzyme replacement therapy (PERT) medication Creon has been extended.
www.thepharmacist.co.uk
January 20, 2026 at 7:47 AM
lgoodbu.bsky.social
www.standard.co.uk/news/uk/alan...
Harry Potter books signed by stars of films up for grabs in prize draw
The draw is raising money for Pancreatic Cancer UK and organised in memory of Alan Rickman, who died of the disease 10 years ago.
www.standard.co.uk
January 20, 2026 at 7:45 AM
lgoodbu.bsky.social
www.bioworld.com/articles/728...
Subpopulation of myofibroblastic CAFs expressing transgelin mediates PDAC progression
Nagoya University Graduate School of Medicine (Japan) and collaborating institutions aimed to characterize the heterogeneity of myofibroblastic cancer-associated fibroblasts (CAFs) in pancreatic ducta...
www.bioworld.com
January 19, 2026 at 10:39 PM
lgoodbu.bsky.social
www.hmpgloballearningnetwork.com/site/onc/cas...
Case Presentation: BRCA2-Directed Therapy in Metastatic Pancreatic Cancer
The Case Presentation: BRCA2-Directed Therapy in Metastatic Pancreatic Cancer Case Presentation from Oncology offers relevant news and insights for medical professionals.
www.hmpgloballearningnetwork.com
January 19, 2026 at 10:36 PM
lgoodbu.bsky.social
www.drugtargetreview.com/news/192390/...
Claudin 18.2-targeted therapy advances GI cancer treatment
Explore how claudin 18.2 can transform cancer treatment for gastric and pancreatic tumours using targeted radiotherapy.
www.drugtargetreview.com
January 19, 2026 at 10:35 PM
lgoodbu.bsky.social
www.youtube.com/watch?v=qx1M...
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January 19, 2026 at 10:34 PM
lgoodbu.bsky.social
pubmed.ncbi.nlm.nih.gov/41097167/?ut...
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway - PubMed
<span><b>Background/Objectives:</b> Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor and leads to high human malignancy and mortality. Because PDAC is highly drug-resistant and current treatments have adverse reactions, exploring novel approaches for PDAC prevention and therapy is urgently nee</span> …
pubmed.ncbi.nlm.nih.gov
January 19, 2026 at 10:33 PM
lgoodbu.bsky.social
www.frontiersin.org/journals/imm...
Frontiers | UNC93B1 Promotes Pancreatic Cancer Progression through Modulation of cGAS–STING Signaling
BackgroundPancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies, largely due to its complex and immunosuppressive tumor microenvironme...
www.frontiersin.org
January 19, 2026 at 10:33 PM