@marionbuckwalter.bsky.social
This is a fabulous paper by Dr. Kristy Zera in my lab. She shows how critical the interaction between VCAM1 on endothelium & VLA4 on immune cells is late after stroke. Blocking either prevents post-stroke cognitive decline & drives mature vessel formation, including pericytes and normal BBB function
Blockade of VCAM1 or VLA4 preserves cerebrovasculature and prevents cognitive decline late after stroke https://www.biorxiv.org/content/10.1101/2025.06.25.661593v1
June 30, 2025 at 4:47 AM
This is a fabulous paper by Dr. Kristy Zera in my lab. She shows how critical the interaction between VCAM1 on endothelium & VLA4 on immune cells is late after stroke. Blocking either prevents post-stroke cognitive decline & drives mature vessel formation, including pericytes and normal BBB function
Reposted
How has stroke research evolved, and where is it headed? In today's episode, physician-scientist @marionbuckwalter.bsky.social shares how decades of scientific discovery shaped what we know about stroke and why continued research is key to future progress.
neuroscience.stanford.edu/news/how-bas...
neuroscience.stanford.edu/news/how-bas...
June 26, 2025 at 7:47 PM
How has stroke research evolved, and where is it headed? In today's episode, physician-scientist @marionbuckwalter.bsky.social shares how decades of scientific discovery shaped what we know about stroke and why continued research is key to future progress.
neuroscience.stanford.edu/news/how-bas...
neuroscience.stanford.edu/news/how-bas...
Reposted
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.
www.training.nih.gov/research-tra...
www.training.nih.gov/research-tra...
www.training.nih.gov
April 10, 2025 at 1:22 AM
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.
www.training.nih.gov/research-tra...
www.training.nih.gov/research-tra...
Reposted
A huge loss at FDA.
Peter Marks originated rhe Operation Warp Speed Covid vaccine idea and has overseen so many essential biotech programs such as genome editing cures www.wsj.com/politics/top...
Peter Marks originated rhe Operation Warp Speed Covid vaccine idea and has overseen so many essential biotech programs such as genome editing cures www.wsj.com/politics/top...
Exclusive | Top Vaccine Official Out at FDA
In his resignation letter, Dr. Peter Marks cited ‘misinformation and lies’ from Health and Human Services Secretary RFK Jr.
www.wsj.com
March 29, 2025 at 1:23 AM
A huge loss at FDA.
Peter Marks originated rhe Operation Warp Speed Covid vaccine idea and has overseen so many essential biotech programs such as genome editing cures www.wsj.com/politics/top...
Peter Marks originated rhe Operation Warp Speed Covid vaccine idea and has overseen so many essential biotech programs such as genome editing cures www.wsj.com/politics/top...
Nice!! This would be outstanding for science, and also for our state’s economy
March 28, 2025 at 3:03 AM
Nice!! This would be outstanding for science, and also for our state’s economy
Reposted
NIH is likely cutting up to 25% of its workforce this week. NIH staff have substantial expertise, typically PhDs. And they really *believe* in the work. NIH's will not be able to meet its mission w/these cuts. The scientific threat is not just direct funding cuts www.statnews.com/2025/03/14/n...
At NIH, ‘everyone is on edge’ as they brace for deep cuts and more centralized control
As the NIH braces for cuts of up to 5,000 of its 20,000 positions, “people are scrambling and freaking out,” a researcher said.
www.statnews.com
March 17, 2025 at 3:45 PM
NIH is likely cutting up to 25% of its workforce this week. NIH staff have substantial expertise, typically PhDs. And they really *believe* in the work. NIH's will not be able to meet its mission w/these cuts. The scientific threat is not just direct funding cuts www.statnews.com/2025/03/14/n...
Reposted
We are in a biotech space race, cutting off basic science via slashing NIH and NSF funding robs the US of our competitive advantage: early innovation.
China is poised to dominate biotechnology in the 21st century - The Hill
March 12, 2025 at 1:34 AM
We are in a biotech space race, cutting off basic science via slashing NIH and NSF funding robs the US of our competitive advantage: early innovation.
Reposted
Kidnapping an activist and jailing him in the middle of the night is a brazen act of authoritarianism.
Punishing dissent by revoking legal status is a dangerous precedent to set.
Punishing dissent by revoking legal status is a dangerous precedent to set.
NEWS: Last night, the Department of Homeland Security detained a Palestinian who helped lead the Columbia encampment.
Agents told him his visa was revoked. He said he had a green card. They were confused—then said that was revoked too.
His attorney demanded a warrant. Agents hung up instead.
Agents told him his visa was revoked. He said he had a green card. They were confused—then said that was revoked too.
His attorney demanded a warrant. Agents hung up instead.
BREAKING: DHS Detains Palestinian Student from Columbia Encampment, Says Advocates
Agents told him his student visa was revoked. But he had a green card. Agents then said that was revoked too.
zeteo.com
March 10, 2025 at 3:14 AM
Kidnapping an activist and jailing him in the middle of the night is a brazen act of authoritarianism.
Punishing dissent by revoking legal status is a dangerous precedent to set.
Punishing dissent by revoking legal status is a dangerous precedent to set.
Reposted
A recent report showed that the destruction of just one USAID program, the anti-AIDS PEPFAR initiative, would lead to the deaths of one million people *every year* www.vox.com/future-perfe...
March 10, 2025 at 4:27 PM
A recent report showed that the destruction of just one USAID program, the anti-AIDS PEPFAR initiative, would lead to the deaths of one million people *every year* www.vox.com/future-perfe...
Palo Alto “Stand up for Science” March 7 2025!!
March 7, 2025 at 11:12 PM
Palo Alto “Stand up for Science” March 7 2025!!
Reposted
Your dignity honors the bravery of the Ukrainian people.
Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.
We will continue working with you for a just and lasting peace.
Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.
We will continue working with you for a just and lasting peace.
February 28, 2025 at 9:06 PM
Your dignity honors the bravery of the Ukrainian people.
Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.
We will continue working with you for a just and lasting peace.
Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.
We will continue working with you for a just and lasting peace.
Reposted
I currently have two fully-funded PhD opportunities in my lab - both providing a chance to work on the incredible LEAF data set that we have been collecting the last couple of years (220 children followed longitudinally from 10-30 months on measures of attention and early EF). Please share!
March 1, 2025 at 1:02 PM
I currently have two fully-funded PhD opportunities in my lab - both providing a chance to work on the incredible LEAF data set that we have been collecting the last couple of years (220 children followed longitudinally from 10-30 months on measures of attention and early EF). Please share!
Reposted
This is incredibly stressful to our Alzheimer's community (families and researchers). There are Alzheimer Disease Research Centers that are in limbo now - no council meetings means no notice of awards, means all the research we are doing to slow or prevent this disease is paused indefinitely.
This. 👇👇👇👇
No study sections, no council meetings = nothing funded. If it's not in the federal register, not happening. Nothing in there after 2/20/25 re: NIH.
Era commons is not being updated. Still says my Advisory Council Meeting was held on 1/28/25 at 3pm. It was not.
Clearly.
1/2
No study sections, no council meetings = nothing funded. If it's not in the federal register, not happening. Nothing in there after 2/20/25 re: NIH.
Era commons is not being updated. Still says my Advisory Council Meeting was held on 1/28/25 at 3pm. It was not.
Clearly.
1/2
I still don't think it's sunk in to many that after February 20th, there ain't no study sections.
February 18, 2025 at 12:55 AM
This is incredibly stressful to our Alzheimer's community (families and researchers). There are Alzheimer Disease Research Centers that are in limbo now - no council meetings means no notice of awards, means all the research we are doing to slow or prevent this disease is paused indefinitely.
Reposted
If you wanted to cut waste, fraud, and abuse, you would empower the inspectors general.
If you wanted more waste, fraud, and abuse, you would fire them.
If you wanted more waste, fraud, and abuse, you would fire them.
February 17, 2025 at 2:17 PM
If you wanted to cut waste, fraud, and abuse, you would empower the inspectors general.
If you wanted more waste, fraud, and abuse, you would fire them.
If you wanted more waste, fraud, and abuse, you would fire them.
We are here. So infuriating and upsetting.
All my life I have studied democratization and autocratization. My 1st field trip was to newly democratic Argentina. I then added autocracies to my portfolio: Cuba, Ven, etc. I think I can recognize the stages of transition to authoritarianism. Here are the boxes Trump has already checked off.
February 17, 2025 at 11:54 PM
We are here. So infuriating and upsetting.
Reposted
Well, the news dump for NIH this weekend was a Saturday evening news dump.
We are hearing about scores of talented scientists and staff being fired via email tonight.
We are hearing about scores of talented scientists and staff being fired via email tonight.
February 16, 2025 at 3:29 AM
Well, the news dump for NIH this weekend was a Saturday evening news dump.
We are hearing about scores of talented scientists and staff being fired via email tonight.
We are hearing about scores of talented scientists and staff being fired via email tonight.
Reposted
"the Department of Veterans Affairs announced the dismissal of more than 1,000 employees who had served for less than two years. That included researchers working on cancer treatment, opioid addiction, prosthetics and burn pit exposure, U.S. Sen. Patty Murray, a Democrat, said Thursday."
February 16, 2025 at 3:48 AM
"the Department of Veterans Affairs announced the dismissal of more than 1,000 employees who had served for less than two years. That included researchers working on cancer treatment, opioid addiction, prosthetics and burn pit exposure, U.S. Sen. Patty Murray, a Democrat, said Thursday."
Reposted
In their rush to destroy our government
The Trump administration fired the workers who keep our nukes safe
And-realizing how badly they screwed up
Are trying to rehire them
But can’t-because they don’t know how to get in touch with the fired workers
The incompetence is unprecedented
The Trump administration fired the workers who keep our nukes safe
And-realizing how badly they screwed up
Are trying to rehire them
But can’t-because they don’t know how to get in touch with the fired workers
The incompetence is unprecedented
February 16, 2025 at 4:06 AM
In their rush to destroy our government
The Trump administration fired the workers who keep our nukes safe
And-realizing how badly they screwed up
Are trying to rehire them
But can’t-because they don’t know how to get in touch with the fired workers
The incompetence is unprecedented
The Trump administration fired the workers who keep our nukes safe
And-realizing how badly they screwed up
Are trying to rehire them
But can’t-because they don’t know how to get in touch with the fired workers
The incompetence is unprecedented
Thank you, Mike Lauer, for your work. The fact that NIH is still cancelling study sections and Council meetings will hold up, or prevent, new discoveries and cures. This should not be buried.
It’s been buried in all the news today, but every scientist in the US should pay attention to this:
Mike Lauer went out on a limb for us all, sending out a memo saying institutes should start awarding grants. And it looks like Trump/Musk fired him for that. 🧪
Mike Lauer went out on a limb for us all, sending out a memo saying institutes should start awarding grants. And it looks like Trump/Musk fired him for that. 🧪
NEW: In a further sign of turmoil at the NIH, Mike Lauer, who oversees the agency's $39 billion extramural budget that goes to research outside the NIH, has resigned effective tomorrow.
This comes after top NIH official Larry Tabak abruptly retired yesterday.
This comes after top NIH official Larry Tabak abruptly retired yesterday.
February 15, 2025 at 2:00 PM
Thank you, Mike Lauer, for your work. The fact that NIH is still cancelling study sections and Council meetings will hold up, or prevent, new discoveries and cures. This should not be buried.
Reposted
Folks: I am NOT affiliated with the group that is using my name to support an economic boycott. Please spread this post, if you would.
February 13, 2025 at 4:05 PM
Folks: I am NOT affiliated with the group that is using my name to support an economic boycott. Please spread this post, if you would.
Reposted
COVID denial to attacks on NIH and universities now: yes, there is a direct line.
Jay Bhattacharya is a living instantiation of that line. He's the Trump NIH director nominee *because* he denied science to help Republicans. And the same billionaires paid for both. 1/
Jay Bhattacharya is a living instantiation of that line. He's the Trump NIH director nominee *because* he denied science to help Republicans. And the same billionaires paid for both. 1/
There’s a direct line between academic “leaders” being willing to tolerate the misinformation in headline #1 5 years ago and headline #2 today.
I don’t know if anyone predicted all this, but many of us tried to warn them these were bad faith actors.
I don’t know if anyone predicted all this, but many of us tried to warn them these were bad faith actors.
February 8, 2025 at 4:45 PM
COVID denial to attacks on NIH and universities now: yes, there is a direct line.
Jay Bhattacharya is a living instantiation of that line. He's the Trump NIH director nominee *because* he denied science to help Republicans. And the same billionaires paid for both. 1/
Jay Bhattacharya is a living instantiation of that line. He's the Trump NIH director nominee *because* he denied science to help Republicans. And the same billionaires paid for both. 1/
Reposted
Executive wants to frame the NIH indirects cut as $4B in savings.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
Direct Economic Contributions
NIH directly supports the economy through investments in research institutions and job formation.
www.nih.gov
February 8, 2025 at 3:08 AM
Executive wants to frame the NIH indirects cut as $4B in savings.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
Reposted
JUST IN: New York health officials are instructing hospitals to subtype all influenza A-positive samples from hospitalized patients within 24 hours in order to detect any potential human cases of H5N1 bird flu.
February 5, 2025 at 2:25 AM
JUST IN: New York health officials are instructing hospitals to subtype all influenza A-positive samples from hospitalized patients within 24 hours in order to detect any potential human cases of H5N1 bird flu.
Reposted
February 2, 2025 at 11:18 PM
Given the dramatic changes wrought by all these executive orders and the attempted layoff of the federal workforce, with lots of chaotic fallout, I can’t help but think - who does the federal government work for? The people, right? Where are the checks and balances? This is unacceptably reckless.
January 31, 2025 at 9:16 PM
Given the dramatic changes wrought by all these executive orders and the attempted layoff of the federal workforce, with lots of chaotic fallout, I can’t help but think - who does the federal government work for? The people, right? Where are the checks and balances? This is unacceptably reckless.