Jeff Coller
@jmcoller.bsky.social
RNA Biologist - Bloomberg Distinguished Professor of mRNA Biology and Therapeutics. Director of the Hopkins RNA Innovation Center. Cofounder - Tevard Biosciences. Cofounder - Alliance for mRNA Medicines. Cofounder - Foundation for mRNA Medicines.
#GetTheMessage - Did you know? After 300+ days in the hospital, Baby KJ went home—sitting up, waving, and growing. His parents were once told to consider end-of-life care. Now they're watching him thrive, thanks to mRNA technology.
www.chop.edu/news/worlds-...
www.chop.edu/news/worlds-...
World's First Patient Treated with Personalized CRISPR Gene Editing Therapy at Children’s Hospital of Philadelphia
Landmark study from CHOP and Penn Medicine showcases the power of customized gene editing therapy to treat patient with rare metabolic disease.
www.chop.edu
October 30, 2025 at 4:00 AM
#GetTheMessage - Did you know? After 300+ days in the hospital, Baby KJ went home—sitting up, waving, and growing. His parents were once told to consider end-of-life care. Now they're watching him thrive, thanks to mRNA technology.
www.chop.edu/news/worlds-...
www.chop.edu/news/worlds-...
Reposted by Jeff Coller
This @science.org article discusses evidence that suggests mRNA vaccines such as the COVID-19 vaccine may also help fight tumors in cancer patients. BDP @jmcoller.bsky.social comments on this possible effect of mRNA vaccines.
www.science.org/content/arti...
www.science.org/content/arti...
A surprise bonus from COVID-19 vaccines: bolstering cancer treatment
Patients who got shots of mRNA before starting a type of cancer immunotherapy lived much longer
www.science.org
October 23, 2025 at 12:51 PM
This @science.org article discusses evidence that suggests mRNA vaccines such as the COVID-19 vaccine may also help fight tumors in cancer patients. BDP @jmcoller.bsky.social comments on this possible effect of mRNA vaccines.
www.science.org/content/arti...
www.science.org/content/arti...
A surprise bonus from COVID-19 vaccines: bolstering cancer treatment | Science | AAAS www.science.org/content/arti...
A surprise bonus from COVID-19 vaccines: bolstering cancer treatment
Patients who got shots of mRNA before starting a type of cancer immunotherapy lived much longer
www.science.org
October 22, 2025 at 5:25 PM
A surprise bonus from COVID-19 vaccines: bolstering cancer treatment | Science | AAAS www.science.org/content/arti...
RFK Jr. is jeopardizing American's lives. Please see this interview published online today in the WSJ.
www.wsj.com/video/series...
www.wsj.com/video/series...
WSJ Opinion: RFK Jr.’s Misguided War on mRNA
Review & Outlook: Robert F. Kennedy, Jr. is using Biden-era mistakes to tarnish a promising technology, and scientists are pushing back.
www.wsj.com
September 5, 2025 at 2:53 PM
RFK Jr. is jeopardizing American's lives. Please see this interview published online today in the WSJ.
www.wsj.com/video/series...
www.wsj.com/video/series...
Halting mRNA vaccine development in the US has broader implications beyond infectious diseases, impeding innovative cancer and rare disease treatments. Science is interconnected; each step forward contributes to collective knowledge and new breakthroughs.
www.sciencenews.org/article/mrna...
www.sciencenews.org/article/mrna...
mRNA vaccines hold promise for many diseases. Now the tech is under fire
Researchers warn that halting federal contracts for mRNA vaccine research could weaken pandemic preparedness and slow medical advances.
www.sciencenews.org
August 21, 2025 at 11:44 PM
Halting mRNA vaccine development in the US has broader implications beyond infectious diseases, impeding innovative cancer and rare disease treatments. Science is interconnected; each step forward contributes to collective knowledge and new breakthroughs.
www.sciencenews.org/article/mrna...
www.sciencenews.org/article/mrna...
Reposted by Jeff Coller
In the @wsj.com, BDP @jmcoller.bsky.social writes about how mRNA vaccines are among the most promising tools in modern medicine and how the United States' leadership in biomedical innovation is now at risk.
www.wsj.com/opinion/rfk-...
www.wsj.com/opinion/rfk-...
Opinion | RFK Jr.’s Dangerous Attack on mRNA Research
Covid-era coercion and misinformation bred public distrust, but the vaccines did save countless lives.
www.wsj.com
August 19, 2025 at 4:59 PM
In the @wsj.com, BDP @jmcoller.bsky.social writes about how mRNA vaccines are among the most promising tools in modern medicine and how the United States' leadership in biomedical innovation is now at risk.
www.wsj.com/opinion/rfk-...
www.wsj.com/opinion/rfk-...
Recent policy changes are putting American biotechnology leadership at risk while potentially restricting access to new treatments. It's time to refocus this debate & prioritize innovation over political rhetoric. Please read my discussion in today's Wall Street Journal.
apple.news/AEckHTX4qTKW...
apple.news/AEckHTX4qTKW...
Opinion | RFK Jr.’s Dangerous Attack on mRNA Research — The Wall Street Journal
Covid-era coercion and misinformation bred public distrust, but the vaccines did save countless lives.
apple.news
August 18, 2025 at 9:04 PM
Recent policy changes are putting American biotechnology leadership at risk while potentially restricting access to new treatments. It's time to refocus this debate & prioritize innovation over political rhetoric. Please read my discussion in today's Wall Street Journal.
apple.news/AEckHTX4qTKW...
apple.news/AEckHTX4qTKW...
Thank you to Science Friday for hosting me and for this important conversation about mRNA technology and current policy directions.
www.sciencefriday.com/segments/mrn...
www.sciencefriday.com/segments/mrn...
What Do mRNA Funding Cuts Mean For Future US Research?
RFK Jr. canceled nearly $500 million in mRNA vaccine research funding. Plus, the latest climate news, from flooding in Alaska to new EVs.
www.sciencefriday.com
August 15, 2025 at 2:32 PM
Thank you to Science Friday for hosting me and for this important conversation about mRNA technology and current policy directions.
www.sciencefriday.com/segments/mrn...
www.sciencefriday.com/segments/mrn...
Thank you Aaron for having the courage to speak out. We need all scientist to follow in Aaron's footsteps, call your local news and give an interview.
Madison local achievement unlocked. I was interviewed live on-air this morning on WORT-FM about mRNA research!
www.wortfm.org/dispelling-t...
www.wortfm.org/dispelling-t...
Dispelling the Myths About mRNA - WORT-FM 89.9
Noted vaccine skeptic RFK, Junior just canceled half a billion dollars worth of federal research grants into mRNA vaccines. We’ll talk with UW Madison Biochemist Aaron Hoskins about why that matters.
www.wortfm.org
August 11, 2025 at 4:17 PM
Thank you Aaron for having the courage to speak out. We need all scientist to follow in Aaron's footsteps, call your local news and give an interview.
Reposted by Jeff Coller
What we heard this week 🧵 #MedSky
"This is a really reckless decision." -- @jmcoller.bsky.social, of @jhu.edu, discussing HHS Secretary Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of #mRNA vaccines.
www.medpagetoday.com/washington-w...
"This is a really reckless decision." -- @jmcoller.bsky.social, of @jhu.edu, discussing HHS Secretary Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of #mRNA vaccines.
www.medpagetoday.com/washington-w...
Pulling the Plug on mRNA Vaccine Development Is 'Reckless,' Experts Say
Puts U.S. at a disadvantage as H5N1 pandemic threat looms
www.medpagetoday.com
August 11, 2025 at 2:00 PM
What we heard this week 🧵 #MedSky
"This is a really reckless decision." -- @jmcoller.bsky.social, of @jhu.edu, discussing HHS Secretary Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of #mRNA vaccines.
www.medpagetoday.com/washington-w...
"This is a really reckless decision." -- @jmcoller.bsky.social, of @jhu.edu, discussing HHS Secretary Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of #mRNA vaccines.
www.medpagetoday.com/washington-w...
mRNA medicines are the best medicine, but thanks to RFK Jr., laughter will have to be our booster shot! #mRNA, #NewYorker
August 7, 2025 at 10:25 PM
mRNA medicines are the best medicine, but thanks to RFK Jr., laughter will have to be our booster shot! #mRNA, #NewYorker
apnews.com/video/medica... experts react to RFK Jr. canceling $500M in vaccines development projects
Medical experts react to RFK Jr. canceling $500M in vaccines development projects
Robert F. Kennedy Jr. announced in a statement Tuesday that 22 projects, totaling $500 million, to develop vaccines using mRNA technology will be halted.
apnews.com
August 7, 2025 at 2:43 PM
apnews.com/video/medica... experts react to RFK Jr. canceling $500M in vaccines development projects
Reposted by Jeff Coller
Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of mRNA vaccines is a disastrous one -- especially with the looming threat of an H5N1 avian influenza pandemic, sources told MedPage Today. @jmcoller.bsky.social
www.medpagetoday.com/washington-w...
www.medpagetoday.com/washington-w...
Pulling the Plug on mRNA Vaccine Development Is 'Reckless,' Experts Say
Puts U.S. at a disadvantage as H5N1 pandemic threat looms
www.medpagetoday.com
August 6, 2025 at 8:28 PM
Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of mRNA vaccines is a disastrous one -- especially with the looming threat of an H5N1 avian influenza pandemic, sources told MedPage Today. @jmcoller.bsky.social
www.medpagetoday.com/washington-w...
www.medpagetoday.com/washington-w...
This decision risks ceding America's competitive advantage in biotechnology to other nations expanding their investments in mRNA research. American patients may increasingly depend on foreign innovation for breakthrough treatments.
www.statnews.com/2025/08/05/m... via @statnews.com
www.statnews.com/2025/08/05/m... via @statnews.com
Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research
Vaccine experts and people steeped in pandemic preparedness expressed horror at the news that RFK Jr. has shut the door in U.S. investment in mRNA vaccine research.
www.statnews.com
August 6, 2025 at 2:01 AM
This decision risks ceding America's competitive advantage in biotechnology to other nations expanding their investments in mRNA research. American patients may increasingly depend on foreign innovation for breakthrough treatments.
www.statnews.com/2025/08/05/m... via @statnews.com
www.statnews.com/2025/08/05/m... via @statnews.com
I nice little story from the lab: dx.plos.org/10.1371/jour...
Biochemical analysis of human eIF4E-DCP2 interaction: Implications for the relationship between translation initiation and decapping
All eukaryotic mRNAs bear a 7-methylguanosine cap on their 5’ end. The 5’ cap enables mRNA translation by binding directly to eIF4E; which further recruits other factors and the 40S ribosome. Addition...
dx.plos.org
August 4, 2025 at 2:48 PM
I nice little story from the lab: dx.plos.org/10.1371/jour...
Reposted by Jeff Coller
New gene therapy approach targets rare genetic diseases by boosting expression of autism-linked genes. "We stand on the brink of medical breakthroughs—we are so close." @jmcoller.bsky.social www.oneneurojhu.org/2025/06/26/a...
June 26, 2025 at 8:03 PM
New gene therapy approach targets rare genetic diseases by boosting expression of autism-linked genes. "We stand on the brink of medical breakthroughs—we are so close." @jmcoller.bsky.social www.oneneurojhu.org/2025/06/26/a...
Reposted by Jeff Coller
In a new @nature.com e article, BDP @jmcoller.bsky.social talks about mRNA’s potential not just in thwarting infectious threats but also in treating many of the same chronic conditions targeted by RFK Jr’s ‘Make America Healthy Again’ initiative.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
How political attacks could crush the mRNA vaccine revolution
Drug makers are scrambling to navigate an ‘existential threat’ to a once-celebrated technology.
www.nature.com
June 3, 2025 at 12:37 PM
In a new @nature.com e article, BDP @jmcoller.bsky.social talks about mRNA’s potential not just in thwarting infectious threats but also in treating many of the same chronic conditions targeted by RFK Jr’s ‘Make America Healthy Again’ initiative.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Jeff Coller
Nature reports how the Trump administration’s anti-mRNA sentiment has sparked fears that this once-celebrated technology, widely seen as a major engine of next-generation vaccines and therapeutics, could soon find itself on the chopping block. #medsky 🧪
How political attacks could crush the mRNA vaccine revolution
Drug makers are scrambling to navigate an ‘existential threat’ to a once-celebrated technology.
go.nature.com
May 22, 2025 at 1:12 AM
Nature reports how the Trump administration’s anti-mRNA sentiment has sparked fears that this once-celebrated technology, widely seen as a major engine of next-generation vaccines and therapeutics, could soon find itself on the chopping block. #medsky 🧪
Reposted by Jeff Coller
Nature reports how the Trump administration’s anti-mRNA sentiment has sparked fears that this once-celebrated technology, widely seen as a major engine of next-generation vaccines and therapeutics, could soon find itself on the chopping block. #medsky 🧪
How political attacks could crush the mRNA vaccine revolution
Drug makers are scrambling to navigate an ‘existential threat’ to a once-celebrated technology.
go.nature.com
May 14, 2025 at 1:44 AM
Nature reports how the Trump administration’s anti-mRNA sentiment has sparked fears that this once-celebrated technology, widely seen as a major engine of next-generation vaccines and therapeutics, could soon find itself on the chopping block. #medsky 🧪
