Rajini Rao
@madamescientist.bsky.social
Scientist, professor, dog mom, gardener and cook. I <3 ion transporters.
Director, Graduate Program in Cellular & Molecular Medicine
Johns Hopkins University School of Medicine
ORCID: 0000-0002-1833-5971
Director, Graduate Program in Cellular & Molecular Medicine
Johns Hopkins University School of Medicine
ORCID: 0000-0002-1833-5971
How did I miss this awesome tutorial on pH microdomains within organelles?! 🤩 🧪
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
January 20, 2026 at 12:24 AM
How did I miss this awesome tutorial on pH microdomains within organelles?! 🤩 🧪
Join us for a day long workshop on Human Organoids featuring cutting edge science, including our keynote talk by Prof. Dan Huh from U Penn. Registration is required, but free! Zoom link available on request. 🧪
January 9, 2026 at 9:51 PM
Join us for a day long workshop on Human Organoids featuring cutting edge science, including our keynote talk by Prof. Dan Huh from U Penn. Registration is required, but free! Zoom link available on request. 🧪
Congratulations, Raghu! You will be brilliant in this role 👏
Way to start the year with a huge humblebrag!
🎉🎉🎉 I have been selected as the Indian Ambassador for @biophysicalsoc.bsky.social seventh cohort (2026-2028)!!! Eagerly looking forward to working with other ambassadors to promote biophysics and bioinfo in India. 🥳 🙌
biophysics.cld.bz/Biophysical-...
🎉🎉🎉 I have been selected as the Indian Ambassador for @biophysicalsoc.bsky.social seventh cohort (2026-2028)!!! Eagerly looking forward to working with other ambassadors to promote biophysics and bioinfo in India. 🥳 🙌
biophysics.cld.bz/Biophysical-...
January 8, 2026 at 6:59 PM
Congratulations, Raghu! You will be brilliant in this role 👏
Welcoming the New Year with black eyed peas and a cheesy gratin of collard greens for good luck 🎉 Happy New Year #foodsky ! What are you celebrating with tonight?
December 31, 2025 at 11:50 PM
Welcoming the New Year with black eyed peas and a cheesy gratin of collard greens for good luck 🎉 Happy New Year #foodsky ! What are you celebrating with tonight?
The best part of the holidays is that I can cook to my heart's content. Cornmeal blueberry pancakes for breakfast, udon noodles in a red curry soup with cabbage and carrot dumplings for dinner. Happy cooking! #foodsky
December 26, 2025 at 5:56 PM
The best part of the holidays is that I can cook to my heart's content. Cornmeal blueberry pancakes for breakfast, udon noodles in a red curry soup with cabbage and carrot dumplings for dinner. Happy cooking! #foodsky
🧪Our paper titled “The Christianson syndrome protein, sodium hydrogen exchanger isoform 6, is required for fat accumulation" was chosen by J Physiol Editor-in-Chief as the Editor’s Choice! 🥳
This is our 1st paper using a mouse model & venturing into adipocyte biology 😍
Open Access: lnkd.in/eGs6sPds
This is our 1st paper using a mouse model & venturing into adipocyte biology 😍
Open Access: lnkd.in/eGs6sPds
November 27, 2025 at 11:18 AM
🧪Our paper titled “The Christianson syndrome protein, sodium hydrogen exchanger isoform 6, is required for fat accumulation" was chosen by J Physiol Editor-in-Chief as the Editor’s Choice! 🥳
This is our 1st paper using a mouse model & venturing into adipocyte biology 😍
Open Access: lnkd.in/eGs6sPds
This is our 1st paper using a mouse model & venturing into adipocyte biology 😍
Open Access: lnkd.in/eGs6sPds
✅Are you a Pre-Med student looking to boost your chances of getting into Med School?
✅Want to try an intensive research program before committing to a PhD?
✅Honing your skills for a competitive job in pharma/biotech?
Apply to our MS in CMM program: cmm.jhmi.edu/index.php/ms...
✅Want to try an intensive research program before committing to a PhD?
✅Honing your skills for a competitive job in pharma/biotech?
Apply to our MS in CMM program: cmm.jhmi.edu/index.php/ms...
November 23, 2025 at 5:55 AM
✅Are you a Pre-Med student looking to boost your chances of getting into Med School?
✅Want to try an intensive research program before committing to a PhD?
✅Honing your skills for a competitive job in pharma/biotech?
Apply to our MS in CMM program: cmm.jhmi.edu/index.php/ms...
✅Want to try an intensive research program before committing to a PhD?
✅Honing your skills for a competitive job in pharma/biotech?
Apply to our MS in CMM program: cmm.jhmi.edu/index.php/ms...
Reposted by Rajini Rao
🍼 Milk: good for babies… and organoids too?
Majood & Rao argue human milk—a living fluid rich in cells, bioactive molecules, & microbiome—could transform lactation biology & contamination research.
💡It's also a vital cell source for the development of 3D mammary #organoid models. 🧪
Majood & Rao argue human milk—a living fluid rich in cells, bioactive molecules, & microbiome—could transform lactation biology & contamination research.
💡It's also a vital cell source for the development of 3D mammary #organoid models. 🧪
![A dark purple, magenta, and white graphic with the following quote: “"[S]tudies on lactation historically rely heavily on animal models which fail to fully recapitulate human lactation physiology, or on healthy breast tissue that is difficult to obtain, especially during lactation, and has limited scalability. Differences between human and animal models include the number and location of mammary glands, the timing and trajectory of mammary gland development, and the composition of milk." The quote is attributed to the linked paper by Misba Majood & Rajini Rao in Pediatric Research, 2025. On the left, a photo of an infant nursing at their mother’s breast.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:in2pnzujy66a7qnesoxha6ar/bafkreievrsjxvz6knlexigeepmj7umheaubntfq2um2nsyx2kx3fovn2c4@jpeg)
November 20, 2025 at 1:33 PM
🍼 Milk: good for babies… and organoids too?
Majood & Rao argue human milk—a living fluid rich in cells, bioactive molecules, & microbiome—could transform lactation biology & contamination research.
💡It's also a vital cell source for the development of 3D mammary #organoid models. 🧪
Majood & Rao argue human milk—a living fluid rich in cells, bioactive molecules, & microbiome—could transform lactation biology & contamination research.
💡It's also a vital cell source for the development of 3D mammary #organoid models. 🧪
Reposted by Rajini Rao
its remarkable to see random suburbanites in their fucking PJs have more courage than the vast majority of america's political, social, and civil elites
October 25, 2025 at 5:41 PM
its remarkable to see random suburbanites in their fucking PJs have more courage than the vast majority of america's political, social, and civil elites
Here come the exceptions!
news.bloomberglaw.com/daily-labor-...
news.bloomberglaw.com/daily-labor-...
Foreign Grads Seeking H-1B Status Avoid $100,000 Trump Fee (1)
Recent international college graduates who are sponsored for H-1B status while in the US won’t be subject to a $100,000 fee imposed on the program, according to new guidance from the Trump administrat...
news.bloomberglaw.com
October 21, 2025 at 7:57 PM
Here come the exceptions!
news.bloomberglaw.com/daily-labor-...
news.bloomberglaw.com/daily-labor-...
Expect deep cuts in PhD admissions throughout the US, including biomedical programs. The current model of PhD training and the current financial climate are simply not compatible. 🧪
www.thecrimson.com/article/2025...
www.thecrimson.com/article/2025...
Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...
www.thecrimson.com
October 21, 2025 at 5:17 PM
Expect deep cuts in PhD admissions throughout the US, including biomedical programs. The current model of PhD training and the current financial climate are simply not compatible. 🧪
www.thecrimson.com/article/2025...
www.thecrimson.com/article/2025...
Reposted by Rajini Rao
I just want to leave this here, so you can block all the US.GOV accounts with a couple of clicks.
bsky.app/profile/did:...
bsky.app/profile/did:...
October 18, 2025 at 3:50 AM
I just want to leave this here, so you can block all the US.GOV accounts with a couple of clicks.
bsky.app/profile/did:...
bsky.app/profile/did:...
I saw a patch of evening sun on the Celosia and this good boy understood the assignment 📷🐾
October 16, 2025 at 9:15 PM
I saw a patch of evening sun on the Celosia and this good boy understood the assignment 📷🐾
Remembering the NYT obit of Yvonne Brill, NASA rocket scientist, which began "She made a mean beef stroganoff, followed her husband from job to job and took eight years off from work to raise three children." 🤦♀️
Please join me in congratulating Woman on her appointment
Woman named as new Archbishop of Canterbury in historic first
October 3, 2025 at 12:15 PM
Remembering the NYT obit of Yvonne Brill, NASA rocket scientist, which began "She made a mean beef stroganoff, followed her husband from job to job and took eight years off from work to raise three children." 🤦♀️
Wrapping up a great conference on acid-base regulation in Copenhagen. Beautiful venue at the Royal Danish Academy. Our Canadian and European colleagues are aghast at the rapid dismantling of science and democracy in the US.
September 10, 2025 at 1:07 PM
Wrapping up a great conference on acid-base regulation in Copenhagen. Beautiful venue at the Royal Danish Academy. Our Canadian and European colleagues are aghast at the rapid dismantling of science and democracy in the US.
Reposted by Rajini Rao
The “problem” with vaccines? They so effective at preventing deaths that they create generations of people that question whether disease was a problem in the first place because they have never experienced the horrors of a world without vaccines.
September 4, 2025 at 7:44 PM
The “problem” with vaccines? They so effective at preventing deaths that they create generations of people that question whether disease was a problem in the first place because they have never experienced the horrors of a world without vaccines.
Ladies and gentleman, this is the state of Goddard Space Flight Ctr of NASA today. Spouse just returned from a trip abroad to this 🤦♀️
August 26, 2025 at 1:13 PM
Ladies and gentleman, this is the state of Goddard Space Flight Ctr of NASA today. Spouse just returned from a trip abroad to this 🤦♀️
Strawberry 🍓 crostata for 4 yo Rhys’ birthday next door 🎉
August 23, 2025 at 7:45 PM
Strawberry 🍓 crostata for 4 yo Rhys’ birthday next door 🎉
If I wrote a book on the joy of picking tomatoes, would you read it? My writing style is irreverent, self deprecating humor
August 23, 2025 at 3:56 PM
If I wrote a book on the joy of picking tomatoes, would you read it? My writing style is irreverent, self deprecating humor
Today's lesson in pointless security: Digitally signed PDFs cannot be merged w/o the signatures disappearing. Apparently, merging is a disallowed modification.
How do I know this? NIH returned the merged Other Support docs on our multi-PI RPPR because the signatures had disappeared 🤡
How do I know this? NIH returned the merged Other Support docs on our multi-PI RPPR because the signatures had disappeared 🤡
August 14, 2025 at 4:47 PM
Today's lesson in pointless security: Digitally signed PDFs cannot be merged w/o the signatures disappearing. Apparently, merging is a disallowed modification.
How do I know this? NIH returned the merged Other Support docs on our multi-PI RPPR because the signatures had disappeared 🤡
How do I know this? NIH returned the merged Other Support docs on our multi-PI RPPR because the signatures had disappeared 🤡
Nature forgives.
Rabbits decapitated the seedlings, bugs destroyed the zucchini and heat made the basil bolt. But we persevered - added chicken wire fencing, more compost and plenty of TLC. This was today's haul. No bushels of tomatoes this year, but a small harvest is better than no harvest. 🙏
Rabbits decapitated the seedlings, bugs destroyed the zucchini and heat made the basil bolt. But we persevered - added chicken wire fencing, more compost and plenty of TLC. This was today's haul. No bushels of tomatoes this year, but a small harvest is better than no harvest. 🙏
August 10, 2025 at 10:36 PM
Nature forgives.
Rabbits decapitated the seedlings, bugs destroyed the zucchini and heat made the basil bolt. But we persevered - added chicken wire fencing, more compost and plenty of TLC. This was today's haul. No bushels of tomatoes this year, but a small harvest is better than no harvest. 🙏
Rabbits decapitated the seedlings, bugs destroyed the zucchini and heat made the basil bolt. But we persevered - added chicken wire fencing, more compost and plenty of TLC. This was today's haul. No bushels of tomatoes this year, but a small harvest is better than no harvest. 🙏
Too many cherry tomatoes? Arrange them cut side down on parchment paper lined skillet and pour corn bread batter over it. Voila! Upside down cherry tomato corn bread. Courtesy of my daughter Anjana. #foodsky
August 10, 2025 at 12:00 AM
Too many cherry tomatoes? Arrange them cut side down on parchment paper lined skillet and pour corn bread batter over it. Voila! Upside down cherry tomato corn bread. Courtesy of my daughter Anjana. #foodsky