Spagnoli_Lab.
@labspagnoli.bsky.social
Developmental and stem cell biology lab. @KCLstemcells
@kingscollegelondon.bsky.social www.spagnolilab.org
Unlocking the control of cell identity and plasticity
Also on the otherside: @LabSpagnoli on the bird & @SpagnoliLab@mas.to
@kingscollegelondon.bsky.social www.spagnolilab.org
Unlocking the control of cell identity and plasticity
Also on the otherside: @LabSpagnoli on the bird & @SpagnoliLab@mas.to
Pinned
Spagnoli_Lab.
@labspagnoli.bsky.social
· Nov 13
Spatially organized cellular communities shape functional tissue architecture in the pancreas
Spatial maps reveal dynamic epithelial-mesenchymal niches shaping pancreatic development and function.
doi.org
🚨 Check out our new paper is now online in its final version!!!
🎉 👏 Congratulations @alejotorrescano.bsky.social who led the study
+ past & current team @labspagnoli.bsky.social
+ collaborators #VigilanteLab @kingslsm.bsky.social
➡️ doi.org/10.1126/scia...
short 🧵 below & more acknowledgments ⤵️
🎉 👏 Congratulations @alejotorrescano.bsky.social who led the study
+ past & current team @labspagnoli.bsky.social
+ collaborators #VigilanteLab @kingslsm.bsky.social
➡️ doi.org/10.1126/scia...
short 🧵 below & more acknowledgments ⤵️
Reposted by Spagnoli_Lab.
🧫 For anyone interested in doing a #PhD in #fertility preservation, #chemotherapy & #macrophages please see this opportunity at @edinuni-irr.bsky.social in #Edinburgh, supervised by Roseanne Rosario, @rodtmitchell.bsky.social & me.
💻 www.findaphd.com/phds/project...
📆 Closing date: 6th March
💻 www.findaphd.com/phds/project...
📆 Closing date: 6th March
Targeting macrophages to protect fertility after chemotherapy at University of Edinburgh on FindAPhD.com
PhD Project - Targeting macrophages to protect fertility after chemotherapy at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
February 5, 2026 at 12:10 PM
🧫 For anyone interested in doing a #PhD in #fertility preservation, #chemotherapy & #macrophages please see this opportunity at @edinuni-irr.bsky.social in #Edinburgh, supervised by Roseanne Rosario, @rodtmitchell.bsky.social & me.
💻 www.findaphd.com/phds/project...
📆 Closing date: 6th March
💻 www.findaphd.com/phds/project...
📆 Closing date: 6th March
Reposted by Spagnoli_Lab.
Want to come do a postdoc with us?
We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!
We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!
February 4, 2026 at 1:00 AM
Want to come do a postdoc with us?
We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!
We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!
👀 Check out @the-node.bsky.social where
@alejotorrescano.bsky.social (first author) share
#behindthepaper stories about our recent paper
⤵️
Behind the paper: “Spatially organized cellular communities shape functional tissue architecture in the pancreas” thenode.biologists.com/behind-the-p...
@alejotorrescano.bsky.social (first author) share
#behindthepaper stories about our recent paper
⤵️
Behind the paper: “Spatially organized cellular communities shape functional tissue architecture in the pancreas” thenode.biologists.com/behind-the-p...
Behind the paper: “Spatially organized cellular communities shape functional tissue architecture in the pancreas” - the Node
Behind the paper story from Alejo Torres Cano on their recent paper describing how spatially organized cellular communities shape functional tissue architecture in the pancreas.
thenode.biologists.com
February 3, 2026 at 4:05 PM
👀 Check out @the-node.bsky.social where
@alejotorrescano.bsky.social (first author) share
#behindthepaper stories about our recent paper
⤵️
Behind the paper: “Spatially organized cellular communities shape functional tissue architecture in the pancreas” thenode.biologists.com/behind-the-p...
@alejotorrescano.bsky.social (first author) share
#behindthepaper stories about our recent paper
⤵️
Behind the paper: “Spatially organized cellular communities shape functional tissue architecture in the pancreas” thenode.biologists.com/behind-the-p...
Reposted by Spagnoli_Lab.
The Elbe Program is offering positions for independent postdocs at the interface between theory (physics, maths, computing) and biology. Join us in Dresden! Deadline 13 March.
February 1, 2026 at 7:07 AM
The Elbe Program is offering positions for independent postdocs at the interface between theory (physics, maths, computing) and biology. Join us in Dresden! Deadline 13 March.
Reposted by Spagnoli_Lab.
PhD position in my lab!
January 28, 2026 at 5:25 PM
PhD position in my lab!
Reposted by Spagnoli_Lab.
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
January 27, 2026 at 6:56 PM
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
Reposted by Spagnoli_Lab.
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
January 23, 2026 at 6:41 AM
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
Reposted by Spagnoli_Lab.
Congratulations to Rashmi and Karolina and also to the technology development studio of the MPI-CBG without whom the screen would not have been possible.
If you are interested in high-content screening in organoid models, you may want to take a look.
If you are interested in high-content screening in organoid models, you may want to take a look.
The group of @anne-grapin.bsky.social developed methods to create functional acinar cells, which are involved in the formation of pancreatic cancer. Rashmiparvathi Keshara, Karolina Kuodyte, and the TDS facility used image-based screen & robust analysis pipeline. www.mpi-cbg.de/news-outreac...
Making human pancreatic acinar cells
Dresden researchers develop novel methods to create acinar cells, which are involved in the formation of pancreatic cancer.
www.mpi-cbg.de
January 22, 2026 at 2:04 PM
Congratulations to Rashmi and Karolina and also to the technology development studio of the MPI-CBG without whom the screen would not have been possible.
If you are interested in high-content screening in organoid models, you may want to take a look.
If you are interested in high-content screening in organoid models, you may want to take a look.
Reposted by Spagnoli_Lab.
Few days left to join our ambitious and innovative program using human induced pluripotent stem cells derived hepatocytes for cell based therapies against liver diseases.
We are looking for 2 motivated, ambitious and determined technical assistants.
karriere.charite.de/stellenangeb...
We are looking for 2 motivated, ambitious and determined technical assistants.
karriere.charite.de/stellenangeb...
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
January 14, 2026 at 10:41 AM
Few days left to join our ambitious and innovative program using human induced pluripotent stem cells derived hepatocytes for cell based therapies against liver diseases.
We are looking for 2 motivated, ambitious and determined technical assistants.
karriere.charite.de/stellenangeb...
We are looking for 2 motivated, ambitious and determined technical assistants.
karriere.charite.de/stellenangeb...
Reposted by Spagnoli_Lab.
279 postdoctoral fellowships!
Download freely our database of postdoctoral fellowships and grants. For each entry, we provide eligibility criteria, $ amount, deadline, etc.
Good luck!
Here: research.jhu.edu/rdt/funding-...
Download freely our database of postdoctoral fellowships and grants. For each entry, we provide eligibility criteria, $ amount, deadline, etc.
Good luck!
Here: research.jhu.edu/rdt/funding-...
January 20, 2026 at 1:22 PM
279 postdoctoral fellowships!
Download freely our database of postdoctoral fellowships and grants. For each entry, we provide eligibility criteria, $ amount, deadline, etc.
Good luck!
Here: research.jhu.edu/rdt/funding-...
Download freely our database of postdoctoral fellowships and grants. For each entry, we provide eligibility criteria, $ amount, deadline, etc.
Good luck!
Here: research.jhu.edu/rdt/funding-...
Reposted by Spagnoli_Lab.
Congratulations to Byung Ho for spearheading this work and our HFSP team!
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
January 9, 2026 at 2:31 PM
Congratulations to Byung Ho for spearheading this work and our HFSP team!
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
Reposted by Spagnoli_Lab.
Join us to study developmental cell biology with a focus on cell migration and morphogenesis.
More info about our research:
www.bischofflab.com
Job posting and application details:
focalplane.biologists.com/cell-biology...
#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
More info about our research:
www.bischofflab.com
Job posting and application details:
focalplane.biologists.com/cell-biology...
#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
January 6, 2026 at 12:41 PM
Join us to study developmental cell biology with a focus on cell migration and morphogenesis.
More info about our research:
www.bischofflab.com
Job posting and application details:
focalplane.biologists.com/cell-biology...
#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
More info about our research:
www.bischofflab.com
Job posting and application details:
focalplane.biologists.com/cell-biology...
#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
Reposted by Spagnoli_Lab.
Mesodermal-niche interactions direct specification and differentiation of pancreatic islet cells in human multilineage organoids https://www.biorxiv.org/content/10.64898/2025.12.13.694117v1
December 14, 2025 at 10:30 AM
Mesodermal-niche interactions direct specification and differentiation of pancreatic islet cells in human multilineage organoids https://www.biorxiv.org/content/10.64898/2025.12.13.694117v1
Reposted by Spagnoli_Lab.
From our lab to yours: Happy Holidays and Best wishes for a great start of 2026 !!! 🎄🎆✨🎈🎄
December 24, 2025 at 3:04 PM
From our lab to yours: Happy Holidays and Best wishes for a great start of 2026 !!! 🎄🎆✨🎈🎄
From our lab to yours: Happy Holidays and Best wishes for a great start of 2026 !!! 🎄🎆✨🎈🎄
December 24, 2025 at 3:04 PM
From our lab to yours: Happy Holidays and Best wishes for a great start of 2026 !!! 🎄🎆✨🎈🎄
Reposted by Spagnoli_Lab.
Apply for Development's Pathway to Independence programme
The programme aims to support a small number of researchers in the fields of developmental biology, stem cells and regeneration as they transition from postdoc to group leader. Read more ⬇️
thenode.biologists.com/apply-for-de...
The programme aims to support a small number of researchers in the fields of developmental biology, stem cells and regeneration as they transition from postdoc to group leader. Read more ⬇️
thenode.biologists.com/apply-for-de...
Apply for Development's Pathway to Independence programme - the Node
Development are currently welcoming applications for our Pathway to Independence (PI) programme, which aims to support a small number of researchers in
thenode.biologists.com
December 18, 2025 at 9:22 PM
Apply for Development's Pathway to Independence programme
The programme aims to support a small number of researchers in the fields of developmental biology, stem cells and regeneration as they transition from postdoc to group leader. Read more ⬇️
thenode.biologists.com/apply-for-de...
The programme aims to support a small number of researchers in the fields of developmental biology, stem cells and regeneration as they transition from postdoc to group leader. Read more ⬇️
thenode.biologists.com/apply-for-de...
Reposted by Spagnoli_Lab.
The Company of Biologists Travelling Fellowships programme: a commitment to support the next generation of scientists
Our Reviews Editor Saanjbati Adhikari surveys 35 years of @biologists.bsky.social's Travelling Fellowships programme for #biologists100:
doi.org/10.1242/dev....
Our Reviews Editor Saanjbati Adhikari surveys 35 years of @biologists.bsky.social's Travelling Fellowships programme for #biologists100:
doi.org/10.1242/dev....
December 17, 2025 at 10:40 AM
The Company of Biologists Travelling Fellowships programme: a commitment to support the next generation of scientists
Our Reviews Editor Saanjbati Adhikari surveys 35 years of @biologists.bsky.social's Travelling Fellowships programme for #biologists100:
doi.org/10.1242/dev....
Our Reviews Editor Saanjbati Adhikari surveys 35 years of @biologists.bsky.social's Travelling Fellowships programme for #biologists100:
doi.org/10.1242/dev....
Reposted by Spagnoli_Lab.
📣 New Pre-print from my lab to wrap-up year!!!
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
Mesodermal-niche interactions direct specification and differentiation of pancreatic islet cells in human multilineage organoids https://www.biorxiv.org/content/10.64898/2025.12.13.694117v1
December 14, 2025 at 4:17 PM
📣 New Pre-print from my lab to wrap-up year!!!
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
📣 New Pre-print from my lab to wrap-up year!!!
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
Mesodermal-niche interactions direct specification and differentiation of pancreatic islet cells in human multilineage organoids https://www.biorxiv.org/content/10.64898/2025.12.13.694117v1
December 14, 2025 at 4:17 PM
📣 New Pre-print from my lab to wrap-up year!!!
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
🎉 🎉 led by #GeorginaGoss with support from
@alejotorrescano.bsky.social @heathermwilson.bsky.social & @habkcl.bsky.social
Pairing #spatialtranscriptomics with #stemcell–derived #multilineage-organoids to elucidate human pancreatic islet development 💥
Reposted by Spagnoli_Lab.
Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"
link.springer.com/article/10.1...
#DevBio 🧪
link.springer.com/article/10.1...
#DevBio 🧪
Keeping up with the neighbours: local synchronisation of cell fate decisions during development - EMBO Reports
Even before the advent of multicellular life, unicellular creatures would communicate with their neighbours to coordinate their behaviours. Multicellular organisms have the particular challenge of orc...
link.springer.com
December 11, 2025 at 3:19 PM
Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"
link.springer.com/article/10.1...
#DevBio 🧪
link.springer.com/article/10.1...
#DevBio 🧪
Reposted by Spagnoli_Lab.
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Reposted by Spagnoli_Lab.
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Reposted by Spagnoli_Lab.
Next week, Development Editor James Wells will be attending the @cshlnews.bsky.social meeting 'Assembloids & Complex Cell-Cell Interactions across Tissues & Organs'.
Speak to Jim about submitting your next manuscript to Development.
Meet our team of Editors:
journals.biologists.com/dev/pages/ed...
Speak to Jim about submitting your next manuscript to Development.
Meet our team of Editors:
journals.biologists.com/dev/pages/ed...
December 1, 2025 at 4:17 PM
Next week, Development Editor James Wells will be attending the @cshlnews.bsky.social meeting 'Assembloids & Complex Cell-Cell Interactions across Tissues & Organs'.
Speak to Jim about submitting your next manuscript to Development.
Meet our team of Editors:
journals.biologists.com/dev/pages/ed...
Speak to Jim about submitting your next manuscript to Development.
Meet our team of Editors:
journals.biologists.com/dev/pages/ed...
Reposted by Spagnoli_Lab.
Research from Professor Francesca Spagnoli reveals how different cell types develop, assemble, and communicate to build a functioning pancreas.🧬
www.kcl.ac.uk/news/researc...
Image credit: Alejo Torres-Cano et al. Sci. Adv. 11,eadx5791(2025). DOI: 10.1126/sciadv.adx5791
www.kcl.ac.uk/news/researc...
Image credit: Alejo Torres-Cano et al. Sci. Adv. 11,eadx5791(2025). DOI: 10.1126/sciadv.adx5791
Research reveals how cells organise to build the pancreas | King's College London
New research from King’s College London shows how different cell types develop, assemble and interact to build a functioning pancreas.
www.kcl.ac.uk
December 1, 2025 at 11:44 AM
Research from Professor Francesca Spagnoli reveals how different cell types develop, assemble, and communicate to build a functioning pancreas.🧬
www.kcl.ac.uk/news/researc...
Image credit: Alejo Torres-Cano et al. Sci. Adv. 11,eadx5791(2025). DOI: 10.1126/sciadv.adx5791
www.kcl.ac.uk/news/researc...
Image credit: Alejo Torres-Cano et al. Sci. Adv. 11,eadx5791(2025). DOI: 10.1126/sciadv.adx5791