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labspagnoli.bsky.social
Spagnoli_Lab.
@labspagnoli.bsky.social
Developmental and stem cell biology lab. @KCLstemcells
@kingscollegelondon.bsky.social‬ www.spagnolilab.org
Unlocking the control of cell identity and plasticity
Also on the otherside: @LabSpagnoli on the bird & @SpagnoliLab@mas.to
November 13, 2025 at 3:56 PM
We built ‘maps’ 👩‍💻 showing that pancreas progenitors with nearby supporting cells form #niches &
used #stemcells to recreate these niches in the lab 🧪🧫
& study how human #betacells develop

🙏Many thanks to the Editor & Reviewers for 👍 insights
🙏 Funding @wellcometrust.bsky.social @ec.europa.eu
November 13, 2025 at 3:56 PM
We used #spatialtranscriptomics at #single-cell resolution to 💡 decode the organization in space of progenitors in the developing #pancreas
🔬 We identified distinct tissue-specific mesenchymal supporting populations from embryonic > adult pancreas

#Dashboard accompanying the paper will be out 🔜 👀📣
November 13, 2025 at 3:56 PM
Massive Congrats Sara! 🎉🎉
November 6, 2025 at 12:17 PM